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References from Novel and disruptive biological strategies for resolving gut health challenges in monogastric food animal production. Local targets link to admitted publications; unresolved targets remain external evidence.
Unresolved reference
2015 · External reference
Probing lipase/esterase libraries for lipid A hydrolasesdiscovery of biocatalysts for the detoxification of bacterially-expressed recombinant protein
10.1039/b312662e · 2004 · External reference
Evolution and ecology of antibiotic resistance genes
10.1111/j.1574-6968.2007.00757.x · 2007 · External reference
Influence of dietary components on development of the microbiota in single-stomached species
10.1079/nrr2006123 · 2006 · External reference
Removal of phosphate from lipid A as a strategy to detoxify lipopolysaccharide
10.1097/00024382-200212000-00013 · 2002 · External reference
Regulation of food intake by inflammatory cytokines in the brain
10.1159/000108280 · 2007 · External reference
The European ban on growth-promoting antibiotics and emerging consequences for human and animal health
10.1093/jac/dkg313 · 2003 · External reference
Zinc resistance of Staphylococcus aureus of animal origin is strongly associated with methicillin resistance
10.1016/j.vetmic.2011.02.014 · 2011 · External reference
Fate and transport of antibiotic residues and antibiotic resistance genes following land application of manure waste
10.2134/jeq2008.0128 · 2009 · External reference
Identification of specific targets for the gut mucosal defense factor intestinal alkaline phosphatase
10.1152/ajpgi.00364.2009 · 2010 · External reference
Evolving enzyme technology: impact on commercial poultry nutrition
10.1079/nrr2006121 · 2006 · External reference
Antimicrobial and promicrobial agents
2001 · External reference
From inflammation to sickness and depression: when the immune system subjugates the brain
10.1038/nrn2297 · 2008 · External reference
Unresolved reference
1999 · External reference
Immune system stimulation reduces the efficiency of tryptophan utilization for body protein deposition in growing pigs
10.2527/jas.2011-4830 · 2012 · External reference
Evolution, consequences and future of plant and animal domestication
10.1038/nature01019 · 2002 · External reference
Structure and function of lipopolysaccharides
10.1016/s1286-4579(02)01604-0 · 2002 · External reference
Unresolved reference
2014 · External reference
Swine nutrition and environment
2013 · External reference
Characterization of brush border membrane-bound alkaline phosphatase activity in different segments of the porcine small intestine
10.1016/s0955-2863(99)00012-1 · 1999 · External reference
Measuring synthesis rates of nitrogen-containing polymers by using stable isotope tracers
10.2527/2006.8413_supple79x · 2006 · External reference
Nonruminant nutrition symposium: understanding protein synthesis and degradation and their pathway regulations
10.2527/jas.2007-0731 · 2008 · External reference
Antimicrobial and heavy metal resistance in commensal enterococci isolated from pigs
10.1016/j.vetmic.2010.09.002 · 2011 · External reference
Country-specific antibiotic use practices impact the human gut resistome
10.1101/gr.155465.113 · 2013 · External reference
Antibiotics as growth promotants: mode of action
10.1081/abio-120005768 · 2002 · External reference
Chylomicrons promote intestinal absorption of lipopolysaccharides
10.1194/jlr.m800156-jlr200 · 2009 · External reference
The use of free amino acids allows formulating very low crude protein diets for piglets
10.2527/jas.2013-6514 · 2014 · External reference
Intestinal alkaline phosphatase is a gut mucosal defense factor maintained by enteral nutrition
10.1073/pnas.0712140105 · 2008 · External reference
Pigs expressing salivary phytase produce low-phosphorus manure
10.1038/90788 · 2001 · External reference
Antimicrobial use in animal feed–time to stop
10.1056/nejm200110183451610 · 2001 · External reference
Analyses of pig genomes provide insight into porcine demography and evolution
10.1038/nature11622 · 2012 · External reference
Antimicrobial resistance profiles of Escherichia coli from common European wild bird species
10.1016/j.vetmic.2009.12.016 · 2010 · External reference
Unresolved reference
2012 · External reference
Gastrointestinal health and function in weaned pigs: a review of feeding strategies to control post-weaning diarrhoea without using in-feed antimicrobial compounds
10.1111/j.1439-0396.2012.01284.x · 2013 · External reference
Synthesis of bacterial polysaccharides via the Wzx/Wzy-dependent pathway
10.1139/cjm-2014-0595 · 2014 · External reference
Antimicrobial-resistant and extraintestinal pathogenic Escherichia coli in retail foods
10.1086/428451 · 2005 · External reference
Immune and endocrine regulation of food intake in sick animals
10.1016/s0739-7240(98)00031-9 · 1998 · External reference
Intestinal alkaline phosphatase prevents metabolic syndrome in mice
10.1073/pnas.1220180110 · 2013 · External reference
Cytokine-induced sickness behavior
10.1016/s0889-1591(02)00077-6 · 2003 · External reference
Whole body protein deposition and plasma amino acid profiles in growing and/or finishing pigs fed increasing levels of sulfur amino acids with and without Escherichia coli lipopolysaccharide challenge
10.2527/jas.53821 · 2012 · External reference
Organic acids as feed additives for young pigs: nutritional and gastrointestinal effects
10.22358/jafs/69953/1998 · 1998 · External reference
Nutritional aspects of leukocytic cytokines
10.1093/jn/118.12.1436 · 1988 · External reference
Monitoring and source tracking of tetracycline resistance genes in lagoons and groundwater adjacent to swine production facilities over a 3-year period
10.1128/aem.00665-07 · 2007 · External reference
Alkaline phosphatases reduce toxicity of lipopolysaccharides in vivo and in vitro through dephosphorylation
10.1016/s0009-9120(02)00330-2 · 2002 · External reference
Biological functions and biogenesis of secreted bacterial outer membrane vesicles
10.1146/annurev.micro.091208.073413 · 2010 · External reference
Early weaning reduces small intestinal alkaline phosphatase expression in pigs
10.3945/jn.109.117267 · 2010 · External reference
Intestinal alkaline phosphatase: multiple biological roles in maintenance of intestinal homeostasis and modulation by diet
10.1111/j.1753-4887.2010.00292.x · 2010 · External reference
Nutritional management of gut health in pigs around weaning
10.1017/s0029665107005484 · 2007 · External reference
Odour from animal production facilities: its relationship to diet
10.1079/nrr200592 · 2005 · External reference
Multidrug resistance – a sign of the times
10.1056/nejm199805073381909 · 1998 · External reference
In-feed antibiotic effects on the swine intestinal microbiome
10.1073/pnas.1120238109 · 2012 · External reference
Evaluation of feed grains with dried skim milk and added carbohydrate sources on weanling pig performance
10.2527/1993.71123376x · 1993 · External reference
Food-borne origins of Escherichia coli causing extraintestinal infections
10.1093/cid/cis502 · 2012 · External reference
Passive protective effect of egg-yolk antibodies against enterotoxigenic Escherichia coli K88+ infection in neonatal and early-weaned piglets
10.1111/j.1574-695x.1999.tb01249.x · 1999 · External reference
Unresolved reference
1979 · External reference
Molecular ecological analysis of dietary and antibiotic-induced alterations of the mouse intestinal microbiota
10.1093/jn/131.6.1862 · 2001 · External reference
Restricting microbial exposure in early life negates the immune benefits associated with gut colonization in environments of high microbial diversity
10.1371/journal.pone.0028279 · 2011 · External reference
Environmentally-acquired bacteria influence microbial diversity and natural innate immune responses at gut surfaces
10.1186/1741-7007-7-79 · 2009 · External reference
Acyloxyacyl hydrolase, a leukocyte enzyme that deacylates bacterial lipopolysaccharides, has phospholipase, lysophospholipase, diacylglycerollipase, and acyltransferase activities in vitro
10.1016/s0021-9258(19)50207-1 · 1992 · External reference
Unresolved reference
1998 · External reference
Unresolved reference
2012 · External reference
Endotoxemia reduces skeletal muscle protein synthesis in neonates
10.1152/ajpendo.00220.2002 · 2002 · External reference
Regulation of muscle protein synthesis in neonatal pigs during prolonged endotoxemia
10.1203/01.pdr.0000110526.02282.f3 · 2004 · External reference
Development aggravates the severity of skeletal muscle catabolism induced by endotoxemia in neonatal pigs
10.1152/ajpregu.00259.2011 · 2012 · External reference
Organic acids for performance enhancement in pig diets
10.1079/095442299108728884 · 1999 · External reference
A high-fat diet is associated with endotoxemia that originates from the gut
10.1053/j.gastro.2012.01.034 · 2012 · External reference
Reduced use of antibiotic growth promoters in diets fed to weanling pigs: dietary tools, part 1
10.1080/10495390600956946 · 2006 · External reference
Weaning is associated with an upregulation of expression of inflammatory cytokines in the intestine of piglets
10.1093/jn/134.3.641 · 2004 · External reference
10.1186/2049-1891-4-1 · 2013 · Admitted local publication
A physiologic function for alkaline phosphatase: endotoxin detoxification
1997 · External reference
Dephosphorylation of endotoxin by alkaline phosphatase in vivo
1997 · External reference
Defective LPS signaling in C3H/HeJ and C57BL/10ScCr mice: mutations in Tlr4 gene
10.1126/science.282.5396.2085 · 1998 · External reference
Of pigs and people
2001 · External reference
Evaluation of chronic immune system stimulation models in growing pigs
10.1017/s1751731111001522 · 2012 · External reference
Bacterial endotoxin: molecular relationships of structure to activity and function
10.1096/fasebj.8.2.8119492 · 1994 · External reference
Endotoxin-induced ileal mucosal hyperpermeability in pigs: role of tissue acidosis
1994 · External reference
Establishment of normal gut microbiota is compromised under excessive hygiene conditions
10.1371/journal.pone.0028284 · 2011 · External reference
A host lipase detoxifies bacterial lipopolysaccharides in the liver and spleen
10.1074/jbc.m609462200 · 2007 · External reference
Nonruminant nutrition Symposium: intestinal glucose sensing and regulation of glucose absorption: implications for swine nutrition
10.2527/jas.2010-3695 · 2011 · External reference
Improvement of phosphorus availability by microbial phytase in broilers and pigs
10.1079/bjn19900052 · 1990 · External reference
Experience of feeding pigs without antibiotics: a European perspective
10.1081/abio-120005772 · 2002 · External reference
Pets and antimicrobial resistance
10.1016/j.cvsm.2008.10.016 · 2009 · External reference
Unresolved reference
2001 · External reference
The mode of growth promotion by antibiotics
10.2527/jas1978.4651447x · 1978 · External reference
Gene expression is altered in piglet small intestine by weaning and dietary glutamine supplementation
10.1093/jn/138.6.1025 · 2008 · External reference
Time course of increased plasma cytokines, cortisol, and urea nitrogen in pigs following intraperitoneal injection of lipopolysaccharide
10.2527/1997.7561514x · 1997 · External reference
Unresolved reference
2014 · External reference
The antibiotic resistome: the nexus of chemical and genetic diversity
10.1038/nrmicro1614 · 2007 · External reference
Dietary glutamine supplementation prevents jejunal atrophy in weaned pigs
10.1093/jn/126.10.2578 · 1996 · External reference