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References from The Golgi-resident protein ACBD3 facilitates the interaction between enteroviral 3A proteins and Exportin-1. Local targets link to admitted publications; unresolved targets remain external evidence.
The life cycle of non-polio enteroviruses and how to target it
10.1038/s41579-018-0005-4 · 2018 · External reference
Structural insights into Acyl-coenzyme A binding domain containing 3 (ACBD3) protein hijacking by picornaviruses
10.1002/pro.3738 · 2019 · External reference
The nuclear pore complex: a target for NS3 protease of Dengue and zika viruses
10.3390/v12060583 · 2020 · External reference
Nucleo-Cytoplasmic transport of ZIKV non-structural 3 protein is mediated by Importin-alpha/beta and exportin CRM-1
10.1128/jvi.01773-22 · 2023 · External reference
KPT-330 inhibitor of CRM1 (XPO1)-mediated nuclear export has selective anti-leukaemic activity in preclinical models of T-cell acute lymphoblastic leukaemia and acute myeloid leukaemia
10.1111/bjh.12231 · 2013 · External reference
The 3A protein from multiple picornaviruses utilizes the golgi adaptor protein ACBD3 to recruit PI4KIIIβ
10.1128/jvi.06778-11 · 2012 · External reference
SARS-CoV-2 ORF6 disrupts innate immune signalling by inhibiting cellular mRNA export
10.1371/journal.ppat.1010349 · 2022 · External reference
Convergent evolution in the mechanisms of ACBD3 recruitment to picornavirus replication sites
10.1371/journal.ppat.1007962 · 2019 · External reference
Picornaviruses: a view from 3A
10.3390/v13030456 · 2021 · External reference
Multiplexed cellular profiling identifies an organoselenium compound as an inhibitor of CRM1-mediated nuclear export
10.1111/tra.12872 · 2022 · External reference
Selinexor, a novel selective inhibitor of nuclear export, reduces SARS-CoV-2 infection and protects the respiratory system in vivo
10.1016/j.antiviral.2021.105115 · 2021 · External reference
Kobuviral Non-structural 3A Proteins Act as molecular harnesses to hijack the host ACBD3 protein
10.1016/j.str.2016.11.021 · 2017 · External reference
Novel anti-enterovirus A71 compounds discovered by repositioning antivirals from the open-source MMV pandemic response box
10.3390/ph17060785 · 2024 · External reference
ACBD3 is an essential pan-enterovirus host factor that mediates the interaction between viral 3A protein and cellular protein PI4KB
10.1128/mbio.02742-18 · 2019 · External reference
The molecular basis of Aichi virus 3A protein activation of phosphatidylinositol 4 kinase IIIbeta, PI4KB, through ACBD3
10.1016/j.str.2016.11.016 · 2017 · External reference
Viral subversion of the chromosome Region maintenance 1 export pathway and its consequences for the cell host
10.3390/v15112218 · 2023 · External reference
CRM1-mediated nuclear export of dengue virus RNA polymerase NS5 modulates interleukin-8 induction and virus production
10.1074/jbc.m808271200 · 2009 · External reference
ACBD3-mediated recruitment of PI4KB to picornavirus RNA replication sites
10.1038/emboj.2011.429 · 2012 · External reference
SARS-CoV 9b protein diffuses into nucleus, undergoes active Crm1 mediated nucleocytoplasmic export and triggers apoptosis when retained in the nucleus
10.1371/journal.pone.0019436 · 2011 · External reference
Structural basis for hijacking of the host ACBD3 protein by bovine and porcine enteroviruses and kobuviruses
10.1007/s00705-019-04490-9 · 2020 · External reference
Picornavirus and enterovirus diversity with associated human diseases
10.1016/j.meegid.2012.10.016 · 2013 · External reference
Exportin 1 inhibition as antiviral therapy
10.1016/j.drudis.2020.06.014 · 2020 · External reference
Structure-function analysis of the coxsackievirus protein 3A: identification of residues important for dimerization, viral rna replication, and transport inhibition
10.1074/jbc.m601122200 · 2006 · External reference
A viral protein that blocks Arf1-Mediated COP-I assembly by inhibiting the guanine Nucleotide Exchange factor GBF1
10.1016/j.devcel.2006.06.005 · 2006 · External reference
CRM1-dependent nuclear export of TRIM28 promotes MAVS K48-linked ubiquitination and suppresses RIG-I-mediated antiviral response
10.3389/fimmu.2026.1744833 · 2026 · External reference