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References from Does cellular iron dysregulation play a causative role in Parkinson’s disease?. Local targets link to admitted publications; unresolved targets remain external evidence.
Oxidative DNA damage in the parkinsonian brain: an apparent selective increase in 8-hydroxyguanine levels in substantia nigra
10.1046/j.1471-4159.1997.69031196.x · 1997 · External reference
T2 relaxation time in patients with Parkinson’s disease
10.1212/wnl.43.4.697 · 1993 · External reference
Ferritin: a cytoprotective antioxidant strategem of endothelium
10.1016/s0021-9258(19)37165-0 · 1992 · External reference
Degeneration of substantia nigra in chronic Parkinson’s disease visualized by transcranial color-coded real-time sonography
10.1212/wnl.45.1.182 · 1995 · External reference
The iron chelator desferrioxamine (Desferal) retards 6-hydroxydopamine-induced degeneration of nigrostriatal dopamine neurons
10.1111/j.1471-4159.1991.tb11444.x · 1991 · External reference
Echogenicity of substantia nigra determined by transcranial ultrasound correlates with severity of parkinsonian symptoms induced by neuroleptic therapy
10.1016/s0006-3223(01)01190-8 · 2001 · External reference
Brain dopamine and the syndromes of Parkinson and Huntington. Clinical, morphological and neurochemical correlations
10.1016/0022-510x(73)90175-5 · 1973 · External reference
Association study between iron-related genes polymorphisms and Parkinson’s disease
10.1007/s00415-002-0704-6 · 2002 · External reference
10.1007/pl00007758
10.1007/pl00007758 · External reference
Clinical, biochemical and molecular genetic correlations in Friedreich’s ataxia
10.1093/hmg/9.2.275 · 2000 · External reference
Iron regulatory proteins in pathobiology
10.1042/0264-6021:3520241 · 2000 · External reference
Sequestration of iron by Lewy bodies in Parkinson’s disease
10.1007/s004010050001 · 2000 · External reference
Abnormal iron deposition associated with lipid peroxidation in transgenic mice expressing interleukin-6 in the brain
10.1097/00005072-199803000-00008 · 1998 · External reference
Iron and iron management proteins in neurobiology
10.1016/s0887-8994(01)00303-4 · 2001 · External reference
Neuroferritinopathy: a window on the role of iron in neurodegeneration
10.1006/bcmd.2002.0589 · 2002 · External reference
Mutation in the gene encoding ferritin light polypeptide causes dominant adult-onset basal ganglia disease
10.1038/ng571 · 2001 · External reference
The genetics of Parkinson’s disease
10.1016/s0959-437x(00)00082-4 · 2000 · External reference
Increased nigral iron content and alterations in other metal ions occurring in brain in Parkinson’s disease
10.1111/j.1471-4159.1989.tb07264.x · 1989 · External reference
Parkinson plus syndrome: diagnosis using high field MR imaging of brain iron
10.1148/radiology.159.2.3961182 · 1986 · External reference
Neuropathology of synuclein aggregates
10.1002/1097-4547(20000715)61:2<121::aid-jnr1>3.0.co;2-4 · 2000 · External reference
Immunohistochemical and biochemical studies demonstrate a distinct profile of alpha-synuclein permutations in multiple system atrophy
10.1093/jnen/59.9.830 · 2000 · External reference
Studies on Parkinson’s disease including X-ray fluorescent spectroscopy of formalin fixed brain tissue
10.1097/00005072-196801000-00001 · 1968 · External reference
Iron regulatory proteins and the molecular control of mammalian iron metabolism
10.1146/annurev.nutr.20.1.627 · 2000 · External reference
Familial aggregation of Parkinson’s disease: a population-based case-control study in Europe. EUROPARKINSON Study Group
10.1212/wnl.52.9.1876 · 1999 · External reference
H-ferritin subunit overexpression in erythroid cells reduces the oxidative stress response and induces multidrug resistance properties
10.1182/blood.v94.10.3593.422k26_3593_3603 · 1999 · External reference
Description of Parkinson’s disease as a clinical syndrome
10.1111/j.1749-6632.2003.tb07458.x · 2003 · External reference
Lack of up-regulation of ferritin is associated with sustained iron regulatory protein-1 binding activity in the substantia nigra of patients with Parkinson’s disease
10.1046/j.1471-4159.2002.01118.x · 2002 · External reference
H ferritin knockout mice: a model of hyperferritinemia in the absence of iron overload
10.1182/blood.v98.3.525 · 2001 · External reference
Neonatal iron potentiates adult MPTP-induced neurodegenerative and functional deficits
10.1016/s1353-8020(00)00028-6 · 2001 · External reference
Controversies about iron in parkinsonian and control substantia nigra
10.55782/ane-1997-1229 · 1997 · External reference
Oxidative damage linked to neurodegeneration by selective alpha-synuclein nitration in synucleinopathy lesions
10.1126/science.290.5493.985 · 2000 · External reference
Nature of inhibition of mitochondrial respiratory complex I by 6-hydroxydopamine
10.1046/j.1471-4159.1996.66052004.x · 1996 · External reference
Distribution of iron in the basal ganglia and neocortex in postmortem tissue in Parkinson’s disease and Alzheimer’s disease
1993 · External reference
Iron in the basal ganglia in Parkinson’s disease. An in vitro study using extended X-ray absorption fine structure and cryo-electron microscopy
10.1093/brain/122.4.667 · 1999 · External reference
Apomorphine protects against MPTP-induced neurotoxicity in mice
10.1002/1531-8257(199907)14:4<612::aid-mds1010>3.0.co;2-6 · 1999 · External reference
MRI, brain iron and experimental Parkinson’s disease
10.1016/0022-510x(92)90247-i · 1992 · External reference
Oxidative stress induces amyloid-like aggregate formation of NACP/alpha-synuclein in vitro
10.1097/00001756-199903170-00011 · 1999 · External reference
Dopaminergic cell death precedes iron elevation in MPTP-injected monkeys
10.1016/s0891-5849(03)00385-x · 2003 · External reference
Molecular control of vertebrate iron metabolism: mRNA-based regulatory circuits operated by iron, nitric oxide, and oxidative stress
10.1073/pnas.93.16.8175 · 1996 · External reference
Alpha-synuclein promotes mitochondrial deficit and oxidative stress
10.1016/s0002-9440(10)64553-1 · 2000 · External reference
Brain iron and ferritin in Parkinson’s and Alzheimer’s diseases
10.1007/bf02252926 · 1990 · External reference
Oxidative stress in Parkinson’s disease
10.1002/ana.10483 · 2003 · External reference
Oxidative stress as a cause of nigral cell death in Parkinson’s disease and incidental Lewy body disease. The Royal Kings and Queens Parkinson’s Disease Research Group
10.1002/ana.410320714 · 1992 · External reference
Genetic or pharmacological iron chelation prevents MPTP-induced neurotoxicity in vivo: a novel therapy for Parkinson’s disease
10.1016/s0896-6273(03)00126-0 · 2003 · External reference
Parkinson’s disease as multifactorial oxidative neurodegeneration: implications for integrative management
2000 · External reference
Ala30Pro mutation in the gene encoding alpha-synuclein in Parkinson’s disease
10.1038/ng0298-106 · 1998 · External reference
Role for NF-kappa B in the regulation of ferritin H by tumor necrosis factor-alpha
10.1074/jbc.270.25.15285 · 1995 · External reference
Excessive iron accumulation in the brain: a possible potential risk of neurodegeneration in Parkinson’s disease
10.1007/bf01291883 · 1997 · External reference
Desferrioxamine and vitamin E protect against iron and MPTP-induced neurodegeneration in mice
10.1007/bf01277665 · 1997 · External reference
Parkinson’s disease. Second of two parts
10.1056/nejm199810153391607 · 1998 · External reference
Parkinson’s disease. First of two parts
10.1056/nejm199810083391506 · 1998 · External reference
Targeted deletion of the gene encoding iron regulatory protein-2 causes misregulation of iron metabolism and neurodegenerative disease in mice
10.1038/84859 · 2001 · External reference
On the occurance of abnormal deposits of iron in the brain in Parkinson’s disease with special reference to its location
10.1136/jnnp.s1-5.19.195 · 1924 · External reference
Attenuation of 6-hydroxydopamine (6-OHDA)-induced nuclear factor-kappaB (NF-kappaB) activation and cell death by tea extracts in neuronal cultures
10.1016/s0006-2952(01)00813-9 · 2002 · External reference
Regulation of the 75-kDa subunit of mitochondrial complex I by iron
10.1074/jbc.m100941200 · 2001 · External reference
Transferrin and iron in normal, Alzheimer’s disease, and Parkinson’s disease brain regions
10.1046/j.1471-4159.1995.65020710.x · 1995 · External reference
Complex I, iron, and ferritin in Parkinson’s disease substantia nigra
10.1002/ana.410360612 · 1994 · External reference
The herbicide paraquat causes up-regulation and aggregation of alpha-synuclein in mice: paraquat and alpha-synuclein
10.1074/jbc.c100560200 · 2002 · External reference
Oxidative stress induces activation of a cytosolic protein responsible for control of iron uptake
10.1006/abbi.1995.1019 · 1995 · External reference
Iron accumulation in the substantia nigra of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced hemiparkinsonian monkeys
10.1016/0304-3940(94)90462-6 · 1994 · External reference
Iron-activated iron uptake: a positive feedback loop mediated by iron regulatory protein 1
10.1023/a:1020743405347 · 2003 · External reference
An oxidative stress-mediated positive-feedback iron uptake loop in neuronal cells
10.1046/j.1471-4159.2002.00971.x · 2002 · External reference
Magnetic resonance imaging in parkinsonism
10.1016/s0733-8619(18)30218-4 · 1992 · External reference
The A53T alpha-synuclein mutation increases iron-dependent aggregation and toxicity
10.1523/jneurosci.20-16-06048.2000 · 2000 · External reference
Copper(II)-induced self-oligomerization of alpha-synuclein
10.1042/0264-6021:3400821 · 1999 · External reference
Actin glutathionylation increases in fibroblasts of patients with Friedreich’s ataxia: a potential role in the pathogenesis of the disease
10.1074/jbc.m301872200 · 2003 · External reference
Iron-mediated generation of the neurotoxin 6-hydroxydopamine quinone by reaction of fatty acid hydroperoxides with dopamine: a possible contributory mechanism for neuronal degeneration in Parkinson’s disease
10.1021/jm970099t · 1997 · External reference
Glutathione in blood of patients with Friedreich’s ataxia
10.1046/j.1365-2362.2001.00922.x · 2001 · External reference
Mutation in the alpha-synuclein gene identified in families with Parkinson’s disease
10.1126/science.276.5321.2045 · 1997 · External reference
Oxidative post-translational modifications of alpha-synuclein in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) mouse model of Parkinson’s disease
10.1046/j.1471-4159.2001.00174.x · 2001 · External reference
Distribution of iron in different brain regions and subcellular compartments in Parkinson’s disease
10.1002/ana.410320717 · 1992 · External reference
Transition metals, ferritin, glutathione, and ascorbic acid in parkinsonian brains
10.1111/j.1471-4159.1989.tb09150.x · 1989 · External reference
Post-transcriptional regulation of human iron metabolism by iron regulatory proteins
10.1006/bcmd.2002.0571 · 2002 · External reference
Infusion of iron into the rat substantia nigra: nigral pathology and dose-dependent loss of striatal dopaminergic markers
10.1002/jnr.490350109 · 1993 · External reference
Increased 8-oxo-dGTPase in the mitochondria of substantia nigral neurons in Parkinson’s disease
10.1002/1531-8249(199912)46:6<920::aid-ana17>3.0.co;2-r · 1999 · External reference
Alterations in glutathione levels in Parkinson’s disease and other neurodegenerative disorders affecting basal ganglia
10.1002/ana.410360305 · 1994 · External reference
Reduced and oxidized glutathione in the substantia nigra of patients with Parkinson’s disease
10.1016/0304-3940(92)90355-b · 1992 · External reference
Selective increase of iron in substantia nigra zona compacta of parkinsonian brains
10.1111/j.1471-4159.1991.tb02017.x · 1991 · External reference
Increased iron (III) and total iron content in post mortem substantia nigra of parkinsonian brain
10.1007/bf01244786 · 1988 · External reference
Manganese: a transition metal protects nigrostriatal neurons from oxidative stress in the iron-induced animal model of parkinsonism
10.1016/s0306-4522(97)00660-x · 1998 · External reference
Characterization of a nonsense mutation in the ceruloplasmin gene resulting in diabetes and neurodegenerative disease
10.1093/hmg/5.1.81 · 1996 · External reference
Iron accumulation in the substantia nigra of autosomal recessive juvenile parkinsonism (ARJP)
10.1016/s1353-8020(00)00050-x · 2001 · External reference
A case of aceruloplasminaemia: abnormal serum ceruloplasmin protein without ferroxidase activity
2002 · External reference
Increased iron in the substantia nigra compacta of the MPTP-lesioned hemiparkinsonian African green monkey: evidence from proton microprobe elemental microanalysis
10.1046/j.1471-4159.1994.62010134.x · 1994 · External reference
Combinatorial mRNA regulation: iron regulatory proteins and iso-iron-responsive elements (Iso-IREs)
10.1074/jbc.r000019200 · 2000 · External reference
Mouse brains deficient in H-ferritin have normal iron concentration but a protein profile of iron deficiency and increased evidence of oxidative stress
10.1002/jnr.10463 · 2003 · External reference
Iron and neurodegenerative disorders
10.1016/s0361-9230(01)00510-x · 2001 · External reference
Nuclear microscopic investigations into the elemental changes in the substantia nigra of unilaterally MPTP-lesioned parkinsonian monkeys
10.1016/s0168-583x(97)00239-5 · 1997 · External reference
Metal-triggered structural transformations, aggregation, and fibrillation of human alpha-synuclein. A possible molecular NK between Parkinson’s disease and heavy metal exposure
10.1074/jbc.m105343200 · 2001 · External reference
Oxidative stress resulting from ultraviolet A irradiation of human skin fibroblasts leads to a heme oxygenase-dependent increase in ferritin
10.1016/s0021-9258(18)82386-9 · 1993 · External reference
Intranigral injected iron progressively reduces striatal dopamine metabolism
10.1007/bf02260941 · 1994 · External reference
Basal ganglia iron content in Parkinson’s disease measured with magnetic resonance
10.1002/mds.870110305 · 1996 · External reference
Immunohistochemical detection of 4-hydroxynonenal protein adducts in Parkinson disease
10.1073/pnas.93.7.2696 · 1996 · External reference
XANES spectroscopy of a single neuron from a patient with Parkinson’s disease
10.1107/s0909049500017726 · 2001 · External reference
The role of monoamine oxidase, iron–melanin interaction, and intracellular calcium in Parkinson’s disease
1990 · External reference
The possible role of iron in the etiopathology of Parkinson’s disease
10.1002/mds.870080102 · 1993 · External reference
