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References from Heme, iron, and the mitochondrial decay of ageing. Local targets link to admitted publications; unresolved targets remain external evidence.
Effect of age on rat liver heme and drug metabolism
10.1016/0531-5565(85)90053-1 · 1985 · External reference
Delaying the mitochondrial decay of ageing-a metabolic tune-up
10.1097/00002093-200304002-00007 · 2003 · External reference
Synthesis of cytochrome c oxidase in the liver of Rana catesbeiana tadpole treated with griseofulvin
10.1016/0167-4781(84)90118-0 · 1984 · External reference
Mutations in COX15 produce a defect in the mitochondrial heme biosynthetic pathway, causing early-onset fatal hypertrophic cardiomyopathy
10.1086/345489 · 2003 · External reference
Heme deficiency selectively interrupts assembly of mitochondrial complex IV in human fibroblasts: revelance to ageing
10.1074/jbc.m108362200 · 2001 · External reference
The role of heme and iron-sulfur clusters in mitochondrial biogenesis, maintenance, and decay with age
10.1006/abbi.2001.2671 · 2002 · External reference
Heme deficiency may be a factor in the mitochondrial and neuronal decay of ageing
10.1073/pnas.192585799 · 2002 · External reference
Biliverdin reductase: a major physiologic cytoprotectant
10.1073/pnas.252626999 · 2002 · External reference
Involvement of mitochondrial ferredoxin and Cox15p in hydroxylation of heme O
10.1016/s0014-5793(01)02249-9 · 2001 · External reference
Aberration of heme and hemoprotein in aged female rats
10.1016/0047-6374(87)90078-9 · 1987 · External reference
Brain metabolism and brain disease: is metabolic deficiency the proximate cause of Alzheimer dementia?
10.1002/jnr.10087 · 2001 · External reference
Quantitative determination of porphyrins in rat and human urine and evaluation of urinary porphyrin profiles during mercury and lead exposures
1992 · External reference
Effects of a single injection of estradiol valerate on the hypothalamic arcuate nucleus and on reproductive function in the female rat
10.1210/endo-103-2-501 · 1978 · External reference
Identification of novel hemes generated by heme A synthase: evidence for two successive monooxygenase reactions
10.1021/bi0203536 · 2002 · External reference
Iron supplementation improves progressive fatigue resistance during dynamic knee extensor exercise in iron-depleted, nonanemic women
10.1093/ajcn/77.2.441 · 2003 · External reference
The metallobiology of Alzheimer’s disease
10.1016/s0166-2236(03)00067-5 · 2003 · External reference
Evidence for a novel heme-binding protein, HasAh, in Alzheimer disease
10.1089/ars.2000.2.1-137 · 2000 · External reference
Ferrochelatase at the millennium: structures, mechanisms and [2Fe-2S] clusters
10.1007/pl00000672 · 2000 · External reference
Identification of an FAD superfamily containing protoporphyrinogen oxidases, monoamine oxidases, and phytoene desaturase. Expression and characterization of phytoene desaturase of Myxococcus xanthus
10.1074/jbc.273.22.13658 · 1998 · External reference
Environmental chemical exposures and disturbances of heme synthesis
10.2307/3433396 · 1997 · External reference
Perinatal iron deficiency decreases cytochrome c oxidase (CytOx) activity in selected regions of neonatal rat brain
10.1203/00006450-200008000-00009 · 2000 · External reference
Inactivation of the human brain muscarinic acetylcholine receptor by oxidative damage catalyzed by a low molecular weight endogenous inhibitor from Alzheimer’s brain is prevented by pyrophosphate analogs, bioflavonoids and other antioxidants
10.1016/s0006-8993(02)02981-5 · 2002 · External reference
Heme and iron metabolism in ageing
1987 · External reference
Nitric oxide-mediated inactivation of mammalian ferrochelatase in vivo and in vitro: possible involvement of the iron-sulphur cluster of the enzyme
10.1042/bj3100533 · 1995 · External reference
Interaction between succinyl CoA synthetase and the heme-biosynthetic enzyme ALAS-E is disrupted in sideroblastic anemia
10.1172/jci6816 · 2000 · External reference
Abnormal iron distribution in infants of diabetic mothers: spectrum and maternal antecedents
10.1016/s0022-3476(05)81097-2 · 1990 · External reference
The alpha-ketoglutarate dehydrogenase complex in neurodegeneration
10.1016/s0197-0186(99)00114-x · 2000 · External reference
Involvement of heme in the degradation of iron-regulatory protein 2
10.1074/jbc.273.20.12555 · 1998 · External reference
Regulation of the mevalonate pathway
10.1038/343425a0 · 1990 · External reference
Formation and disposition of newly synthesized heme in adult rat hepatocytes in primary culture
10.1016/s0021-9258(19)68459-0 · 1981 · External reference
Intravenous iron supplementation effect on tissue iron and hemoproteins in chronically phlebotomized lambs
1997 · External reference
The steady state concentrations of coenzyme A-SH and coenzyme A thioester, citrate, and isocitrate during tricarboxylate cycle oxidations in rabbit heart mitochondria
10.1016/s0021-9258(19)40767-9 · 1975 · External reference
Hemin and related porphyrins inhibit beta-amyloid aggregation
10.1016/s0014-5793(97)01290-8 · 1997 · External reference
Early childhood anemia and mild or moderate mental retardation
10.1093/ajcn/69.1.115 · 1999 · External reference
Effects of low doses of dietary lead on red blood cell production in male and female mice
10.1016/s0378-4274(02)00404-6 · 2003 · External reference
The regulation of heme turnover and carbon monoxide biosynthesis in cultured primary rat olfactory receptor neurons
10.1523/jneurosci.16-18-05621.1996 · 1996 · External reference
Physiological roles of animal succinate thiokinases. Specific association of the guanine nucleotide-linked enzyme with haem biosynthesis
10.1016/0014-5793(88)80629-x · 1988 · External reference
Genetic evidence for the expression of ATP- and GTP-specific succinyl-CoA synthetases in multicellular eucaryotes
10.1074/jbc.273.42.27580 · 1998 · External reference
Hepatic heme metabolism in rats with fever induced by interleukin 1beta
1999 · External reference
Iron accumulation during cellular senescence in human fibroblasts in vitro
10.1089/152308603770310158 · 2003 · External reference
Hemin-induced activation of the thioredoxin gene by Nrf2. A differential regulation of the antioxidant responsive element by a switch of its binding factors
10.1074/jbc.m100103200 · 2001 · External reference
Increased bilirubins and their derivatives in cerebrospinal fluid in Alzheimer’s disease
10.1016/s0197-4580(00)00128-7 · 2000 · External reference
Mechanism of iron transport to the site of heme synthesis inside yeast mitochondria
10.1074/jbc.274.27.18989 · 1999 · External reference
Control of heme synthesis during Friend cell differentiation: role of iron and transferrin
10.1002/jcp.1041290209 · 1986 · External reference
Maturation of cellular Fe-S proteins: an essential function of mitochondria
10.1016/s0968-0004(00)01589-9 · 2000 · External reference
Poorer behavioral and developmental outcome more than 10 years after treatment for iron deficiency in infancy
10.1542/peds.105.4.e51 · 2000 · External reference
Heme oxygenase: function, multiplicity, regulatory mechanisms, and clinical applications
10.1096/fasebj.2.10.3290025 · 1988 · External reference
A selective defect of cytochrome c oxidase is present in brain of Alzheimer disease patients
10.1016/s0197-4580(00)00112-3 · 2000 · External reference
Heme oxygenase-2 is a hemoprotein and binds heme through heme regulatory motifs that are not involved in heme catalysis
10.1074/jbc.272.19.12568 · 1997 · External reference
Evidence for association of anaemia with vascular dementia
10.1097/00001756-199908020-00029 · 1999 · External reference
Unresolved reference
External reference
Biosynthesis and functional role of haem O and haem A
10.1111/j.1365-2958.1994.tb02174.x · 1994 · External reference
Heme deficiency in erythroid lineage causes differentiation arrest and cytoplasmic iron overload
10.1093/emboj/18.22.6282 · 1999 · External reference
Changes in the mitochondrial enzyme activity in striatal projection areas after unilateral excitotoxic striatal lesions: partial restoration by embryonic striatal transplants
10.1006/exnr.1998.6883 · 1998 · External reference
Assembly of cytochrome-c oxidase in cultured human cells
10.1046/j.1432-1327.1998.2540389.x · 1998 · External reference
Cdk5 is a key factor in tau aggregation and tangle formation in vivo
10.1016/s0896-6273(03)00259-9 · 2003 · External reference
Heme mediates derepression of Maf recognition element through direct binding to transcription repressor Bach1
10.1093/emboj/20.11.2835 · 2001 · External reference
The key role of anaplerosis and cataplerosis for citric acid cycle function
10.1074/jbc.r200006200 · 2002 · External reference
Lead induced oxidative damage and its response to combined administration of alpha-lipoic acid and succimers in rats
10.1016/s0300-483x(02)00223-8 · 2002 · External reference
Electron transport chain defects in Alzheimer’s disease brain
10.1212/wnl.44.6.1090 · 1994 · External reference
Unresolved reference
External reference
Cell biology of heme
10.1097/00000441-199910000-00004 · 1999 · External reference
Treatment of rats with glucagon or mannoheptulose increases mitochondrial 3-hydroxy-3-methylglutaryl-CoA synthase activity and decreases succinyl-CoA content in liver
10.1042/bj2620159 · 1989 · External reference
Heme oxygenase-1: role in brain ageing and neurodegeneration
10.1016/s0531-5565(00)00148-0 · 2000 · External reference
Role of porphyrin sequestration in the biogenesis of iron-laden astrocytic inclusions in primary culture
10.1159/000065692 · 2002 · External reference
Function of the [2FE-2S] cluster in mammalian ferrochelatase: a possible role as a nitric oxide sensor
10.1021/bi952631p · 1996 · External reference
10.1089/15230860050192198 · 2000 · Admitted local publication
Nitric oxide and carbon monoxide: parallel roles as neural messengers
10.1016/s0165-0173(97)00032-5 · 1998 · External reference
Defining iron-deficiency anemia in public health terms: a time for reflection
10.1093/jn/131.2.565s · 2001 · External reference
Amyloid precursor proteins inhibit heme oxygenase activity and augment neurotoxicity in Alzheimer’s disease
10.1016/s0896-6273(00)00125-2 · 2000 · External reference
Regulation of the expression of human ferrochelatase by intracellular iron levels
10.1046/j.1432-1327.2000.01519.x · 2000 · External reference
Haem can bind to and inhibit mammalian calcium-dependent Slo1 BK channels
10.1038/nature02003 · 2003 · External reference
Iron and neurodegenerative disorders
10.1016/s0361-9230(01)00510-x · 2001 · External reference
Liver haem metabolism in adjuvant-induced arthritic rats
10.3109/00498259609046720 · 1996 · External reference
Unresolved reference
External reference
Energy hypometabolism in posterior cingulate cortex of Alzheimer’s patients: superficial laminar cytochrome oxidase associated with disease duration
10.1523/jneurosci.21-13-04923.2001 · 2001 · External reference
Adaptive changes in the expression of nuclear and mitochondrial encoded subunits of cytochrome c oxidase and the catalytic activity during hypoxia
10.1046/j.1432-1033.2003.03447.x · 2003 · External reference
A protein kinase associated with paired helical filaments in Alzheimer disease
10.1073/pnas.89.7.2878 · 1992 · External reference
A possible role of copper in the regulation of heme biosynthesis through ferrochelatase
10.1007/978-1-4615-9026-2_24 · 1975 · External reference
Dietary intake, dietary patterns, and changes with age: an epidemiological perspective
10.1093/gerona/56.suppl_2.65 · 2001 · External reference
Iron deficiency and iron excess damage mitochondria and mitochondrial DNA in rats
10.1073/pnas.261708798 · 2002 · External reference
Studies on porphyrin-heme biosynthesis in organotypic cultures of chick dorsal root ganglion. I. Observations on neuronal and non-neuronal elements
10.1097/00005072-197809000-00005 · 1978 · External reference
Heme a induces assembly of rat liver cytochrome c oxidase subunits I–III in isolated mitochondria
10.1016/0014-5793(84)81302-2 · 1984 · External reference
The effect of iron substrate on mitochondrial haem synthesis in copper deficiency
10.1079/bjn19850017 · 1985 · External reference
Studies on the role of heme in the regulation of delta-aminolevulinic acid synthetase during fetal hepatic development
1974 · External reference
Developmental aspects of hepatic heme biosynthetic capability and hematotoxicity
10.1016/0006-2952(76)90126-x · 1976 · External reference
Oxidative damage during ageing targets mitochondrial aconitase
10.1073/pnas.94.21.11168 · 1997 · External reference
Heme binds to a short sequence that serves a regulatory function in diverse proteins
10.1002/j.1460-2075.1995.tb07005.x · 1995 · External reference
Heme initiates changes in the expression of a wide array of genes during the early erythroid differentiation stage
10.1006/bbrc.1999.0586 · 1999 · External reference
Heme deficiency interferes with the Ras-mitogen-activated protein kinase signaling pathway and expression of a subset of neuronal genes
2002 · External reference
