Research graph
References from What can narcolepsy teach us about hypocretin and dementia?. Local targets link to admitted publications; unresolved targets remain external evidence.
Neuronal activity regulates the regional vulnerability to amyloid-β deposition
10.1038/nn.2801 · 2011 · External reference
Ambulatory 24 h sleep-wake monitoring in narcolepsy-cataplexy compared to matched controls
10.1016/0013-4694(88)90145-9 · 1988 · External reference
Association of excessive daytime sleepiness with longitudinal β-amyloid accumulation in elderly persons without dementia
10.1001/jamaneurol.2018.0049 · 2018 · External reference
Synaptic activity regulates interstitial fluid amyloid-β levels in vivo
10.1016/j.neuron.2005.10.028 · 2005 · External reference
Decreased concentration of klotho and increased concentration of FGF23 in the cerebrospinal fluid of patients with narcolepsy
10.1016/j.sleep.2020.11.037 · 2021 · External reference
Delayed orexin signaling consolidates wakefulness and sleep: physiology and modeling
10.1152/jn.01243.2007 · 2008 · External reference
Reduced brain amyloid burden in elderly patients with narcolepsy type 1
10.1002/ana.25373 · 2019 · External reference
The sleep-wake cycle regulates brain interstitial fluid tau in mice and CSF tau in humans
10.1126/science.aav2546 · 2019 · External reference
Cerebrospinal fluid biomarkers of neurodegeneration are decreased or normal in narcolepsy
2017 · External reference
Amyloid-β dynamics are regulated by orexin and the sleep-wake cycle
10.1126/science.1180962 · 2009 · External reference
Effects of oveporexton, an orexin receptor 2-selective agonist, on cognition in narcolepsy type 1
10.1001/jamaneurol.2025.4825 · 2026 · External reference
Using actigraphy to assess sleep and wake rhythms of narcolepsy type 1 patients: a comparison with primary insomniacs and healthy controls
10.1016/j.sleep.2018.07.024 · 2018 · External reference
CSF beta-amyloid levels are altered in narcolepsy: a link with the inflammatory hypothesis?
10.1111/jsr.12130 · 2014 · External reference
Orexinergic system dysregulation, sleep impairment, and cognitive decline in Alzheimer disease
10.1001/jamaneurol.2014.2510 · 2014 · External reference
Implications from proteomic studies investigating circadian rhythm disorder-regulated neurodegenerative disease pathology
10.1016/j.smrv.2023.101789 · 2023 · External reference
CSF dynamics of orexin and β-amyloid42 levels in narcolepsy and Alzheimer’s disease patients: a controlled study
10.1016/j.neulet.2024.137914 · 2024 · External reference
Effect of sleep on overnight cerebrospinal fluid amyloid β kinetics
10.1002/ana.25117 · 2018 · External reference
Potential role of orexin and sleep modulation in the pathogenesis of Alzheimer’s disease
10.1084/jem.20141788 · 2014 · External reference
Coexistence of narcolepsy and Alzheimer’s disease
10.1016/j.neurobiolaging.2010.12.008 · 2012 · External reference
Narcolepsy with long sleep time: a specific entity?
10.1093/sleep/32.9.1229 · 2009 · External reference
Neuronal activity regulates extracellular tau in vivo
10.1084/jem.20131685 · 2014 · External reference
The orexin/hypocretin system in dementia-related neurological disorders: a double-edged sword in cognitive impairment
10.1007/s00213-025-06839-2 · 2025 · External reference
