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References from GNG7 attenuates inflammation and modulates macrophage function via the NF-κB/NLRP3 inflammasome pathways in Poly I:C-induced acute lung injury. Local targets link to admitted publications; unresolved targets remain external evidence.
Comparison of clinical features and outcomes between SARS-CoV-2 and non-SARS-CoV-2 respiratory viruses associated acute respiratory distress syndrome: retrospective analysis
10.3390/jcm11082246 · 2022 · External reference
Acute respiratory distress syndrome
10.1038/s41572-019-0069-0 · 2019 · External reference
Deep insight into cytokine storm: from pathogenesis to treatment
10.1038/s41392-025-02178-y · 2025 · External reference
Single-cell spatiotemporal analysis of the lungs reveals Slamf9+ macrophages involved in viral clearance and inflammation resolution
10.1038/s41421-024-00734-4 · 2024 · External reference
Cannabinoids alleviate the LPS-induced cytokine storm via attenuating NLRP3 inflammasome signaling and TYK2-mediated STAT3 signaling pathways in vitro
10.3390/cells11091391 · 2022 · External reference
A functionally distinct neutrophil landscape in severe COVID-19 reveals opportunities for adjunctive therapies
10.1172/jci.insight.152291 · 2022 · External reference
The role of macrophages polarization in sepsis-induced acute lung injury
2023 · External reference
Unraveling the functional significance of unstructured regions in G protein-coupled receptors
10.3390/biom13101431 · 2023 · External reference
G protein-coupled receptors and heterotrimeric G proteins as cancer drivers
10.1002/1873-3468.14017 · 2020 · External reference
GNG7 as a tumor-suppressor gene in lung adenocarcinoma: implications for prognosis and immune-based therapies
2025 · External reference
Long non-coding RNA LINC00472 inhibits oral squamous cell carcinoma via miR-4311/GNG7 axis
10.1080/21655979.2022.2040768 · 2022 · External reference
Osthole inhibits breast cancer progression through upregulating tumor suppressor GNG7
10.1155/2021/6610511 · 2021 · External reference
Transcriptional profiles of peripheral eosinophils in chronic obstructive pulmonary disease and asthma-an exploratory study
10.1111/jcmm.70110 · 2024 · External reference
An epigenome-wide DNA methylation study of patients with COVID-19
10.1111/ahg.12440 · 2021 · External reference
PolyI:C upregulated CCR5 and promoted THP-1-derived macrophage chemotaxis via TLR3/JMJD1A signalling
2020 · External reference
GPR40 activation alleviates pulmonary fibrosis by repressing M2 macrophage polarization through the PKD1/CD36/TGF-β1 pathway
10.1038/s41401-025-01558-y · 2025 · External reference
Lumican is elevated in the lung in human and experimental acute respiratory distress syndrome and promotes early fibrotic responses to lung injury
10.1186/s12967-022-03597-z · 2022 · External reference
An official American Thoracic Society workshop report: features and measurements of experimental acute lung injury in animals
10.1165/rcmb.2009-0210st · 2011 · External reference
Macrophages as multifaceted orchestrators of tissue repair: bridging inflammation, regeneration, and therapeutic innovation
10.2147/jir.s527764 · 2025 · External reference
Sanzi Yangqin decoction improved acute lung injury by regulating the TLR2-mediated NF-κB/NLRP3 signaling pathway and inhibiting the activation of NLRP3 inflammasome
10.1016/j.phymed.2025.156438 · 2025 · External reference
Establishment of a lncRNA-miRNA-mRNA network in a rat model of atrial fibrosis by whole transcriptome sequencing
10.1007/s10840-022-01120-4 · 2022 · External reference
Polygala tenuifolia willd. Extract alleviates LPS-induced acute lung injury in rats via TLR4/NF-κB pathway and NLRP3 inflammasome suppression
10.1016/j.phymed.2024.155859 · 2024 · External reference
Updated insights into the molecular networks for NLRP3 inflammasome activation
10.1038/s41423-025-01284-9 · 2025 · External reference
Triclosan induces liver injury in long-life exposed mice via activation of TLR4/NF-κB/NLRP3 pathway
10.1016/j.ecoenv.2024.116115 · 2024 · External reference
Hypoxic preconditioning attenuates Neuroinflammation via inhibiting NF-κB/NLRP3 Axis mediated by p-MLKL after transient global cerebral ischemia
10.1007/s12035-023-03628-w · 2024 · External reference
In vitro and in vivo evidence on the association of pregnant PM2.5 exposure with preterm birth and potential role of placental miRNA-21 regulating TLR4/NF-κB and activating NLRP3 inflammasome
10.1016/j.jhazmat.2025.138376 · 2025 · External reference
5-deoxy-rutaecarpine protects against LPS-induced acute lung injury via inhibiting NLRP3 inflammasome-related inflammation
2025 · External reference
Exploring immune-related pathogenesis in lung injury: providing new insights into ALI/ARDS
10.1016/j.biopha.2024.116773 · 2024 · External reference
Molecular mechanisms of emerging inflammasome complexes and their activation and signaling in inflammation and pyroptosis
10.1111/imr.13406 · 2025 · External reference
TRPM2 links oxidative stress to NLRP3 inflammasome activation
10.1038/ncomms2608 · 2013 · External reference
Hydrogen attenuates cognitive impairment in rat models of vascular dementia by inhibiting oxidative stress and NLRP3 inflammasome activation
10.1002/adhm.202400400 · 2024 · External reference
The NOX2-ROS-NLRP3 inflammasome axis in traumatic brain injury
10.1186/s12974-025-03535-y · 2025 · External reference
TLR4-NOX2 axis regulates the phagocytosis and killing of mycobacterium tuberculosis by macrophages
10.1186/s12890-017-0517-0 · 2017 · External reference
Light-powered phagocytic macrophage microrobot (phagobot): both in vitro and in vivo
10.1038/s41377-025-01881-3 · 2025 · External reference
The role of immunometabolism in macrophage polarization and its impact on acute lung injury/acute respiratory distress syndrome
2023 · External reference
Macrophage polarization and its role in the pathogenesis of acute lung injury/acute respiratory distress syndrome
10.1007/s00011-020-01378-2 · 2020 · External reference
Overcoming adaptive resistance in AML by synergistically targeting FOXO3A-GNG7-mTOR axis with gardenoside and rapamycin
10.1016/j.gendis.2023.01.002 · 2023 · External reference
Non-canonical signaling initiated by hormone-responsive G protein-coupled receptors from subcellular compartments
10.1016/j.pharmthera.2024.108788 · 2025 · External reference
Gβγ subunits-different spaces, different faces
10.1016/j.phrs.2016.06.026 · 2016 · External reference
Macrophages in immunoregulation and therapeutics
10.1038/s41392-023-01452-1 · 2023 · External reference
The prognostic value of GNG7 in colorectal cancer and its relationship with immune infiltration
10.3389/fgene.2022.833013 · 2022 · External reference
