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References from Limiting the intracellular calcium accumulation alleviates fibroblast senescence and pulmonary fibrosis. Local targets link to admitted publications; unresolved targets remain external evidence.
Cellular senescence and senolytics: the path to the clinic
10.1038/s41591-022-01923-y · 2022 · External reference
Senescence in health and disease
10.1016/j.cell.2017.05.015 · 2017 · External reference
Cellular senescence and its effector programs
10.1101/gad.235184.113 · 2014 · External reference
Biomarkers of aging
10.1007/s11427-023-2305-0 · 2023 · External reference
Hesperidin inhibits lung fibroblast senescence via IL-6/STAT3 signaling pathway to suppress pulmonary fibrosis
2023 · External reference
Risk factors for interstitial lung disease: a 9-year Nationwide population-based study
10.1186/s12890-018-0660-2 · 2018 · External reference
Natural senotherapeutics in respiratory health: addressing cellular senescence, inflammaging, and immunosenescence in the aging lung
10.1016/j.ejphar.2026.178620 · 2026 · External reference
Calcium overload and mitochondrial metabolism
10.3390/biom12121891 · 2022 · External reference
Regulation and role of calcium in cellular senescence
10.1016/j.ceca.2023.102701 · 2023 · External reference
Calcium transferring from ER to mitochondria via miR-129/ITPR2 axis controls cellular senescence in vitro and in vivo
10.1016/j.mad.2024.111902 · 2024 · External reference
The effects of artificial calcium buffers on calcium responses and glutamate-mediated excitotoxicity in cultured hippocampal neurons
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Pharmaceutical targeting of succinate dehydrogenase in fibroblasts controls bleomycin-induced lung fibrosis
10.1016/j.redox.2021.102082 · 2021 · External reference
Endoplasmic reticulum calcium release through ITPR2 channels leads to mitochondrial calcium accumulation and senescence
10.1038/ncomms4792 · 2014 · External reference
Calcium channel ITPR2 and mitochondria-ER contacts promote cellular senescence and aging
10.1038/s41467-021-20993-z · 2021 · External reference
TRPC1 links calcium signaling to cellular senescence in the protection against posttraumatic osteoarthritis
10.1172/jci.insight.182103 · 2024 · External reference
Fibroblast senescence in idiopathic pulmonary fibrosis
10.3389/fcell.2020.593283 · 2020 · External reference
Fibrosis: from mechanisms to medicines
10.1038/s41586-020-2938-9 · 2020 · External reference
Pathogenic mechanisms underlying idiopathic pulmonary fibrosis
10.1146/annurev-pathol-042320-030240 · 2022 · External reference
Raised intracellular calcium contributes to ischemia-induced depression of evoked synaptic transmission
10.1371/journal.pone.0148110 · 2016 · External reference
Calcium alterations signal either to senescence or to autophagy induction in stem cells upon oxidative stress
10.18632/aging.101130 · 2016 · External reference
A biomarker that identifies senescent human cells in culture and in aging skin in vivo
10.1073/pnas.92.20.9363 · 1995 · External reference