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References from Caffeic acid phenethyl ester inhibits adipogenic differentiation in association with INSR suppression and AMPK activation. Local targets link to admitted publications; unresolved targets remain external evidence.
Novel insights into regulators and functional modulators of adipogenesis
10.1016/j.biopha.2024.117073 · 2024 · External reference
Inhibition of fatty acid synthase prevents preadipocyte differentiation
10.1016/j.bbrc.2005.01.067 · 2005 · External reference
Differential roles of insulin receptor in adipocyte progenitor cells in mice
10.1016/j.mce.2023.111968 · 2023 · External reference
Muscle conditional medium reduces intramuscular adipocyte differentiation and lipid accumulation through regulating insulin signaling
10.3390/ijms18081799 · 2017 · External reference
Small-molecule COH-SR4 inhibits adipocyte differentiation via AMPK activation
10.3892/ijmm.2013.1313 · 2013 · External reference
A novel peptide suppresses adipogenic differentiation through activation of the AMPK pathway
10.1016/j.bbrc.2019.01.112 · 2019 · External reference
Signaling networks in immunometabolism
10.1038/s41422-020-0301-1 · 2020 · External reference
Insulin inhibits AMPK activity and phosphorylates AMPK Ser485/491 through Akt in hepatocytes, myotubes and incubated rat skeletal muscle
10.1016/j.abb.2014.08.013 · 2014 · External reference
Caffeic acid phenethyl ester improves metabolic syndrome by activating PPAR-γ and inducing adipose tissue remodeling in diet-induced obese mice
10.1002/mnfr.201700701 · 2018 · External reference
Caffeic acid phenethyl ester, a major component of propolis, suppresses high fat diet-induced obesity through inhibiting adipogenesis at the mitotic clonal expansion stage
10.1021/jf405088f · 2014 · External reference
Caffeic acid phenethyl ester regulates PPAR'S levels in stem cells-derived adipocytes
10.1155/2016/7359521 · 2016 · External reference
CAPE (caffeic acid phenethyl ester) stimulates glucose uptake through AMPK (AMP-activated protein kinase) activation in skeletal muscle cells
10.1016/j.bbrc.2007.07.068 · 2007 · External reference
Effect of CAPE-pNO(2) against type 2 diabetes mellitus via the AMPK/GLUT4/GSK3β/PPARα pathway in HFD/STZ-induced diabetic mice
10.1016/j.ejphar.2019.03.027 · 2019 · External reference
Alpha-glucosidase inhibitor 1-Deoxynojirimycin promotes beige remodeling of 3T3-L1 preadipocytes via activating AMPK
10.1016/j.bbrc.2019.01.023 · 2019 · External reference
Tschimganidine reduces lipid accumulation through AMPK activation and alleviates high-fat diet-induced metabolic diseases
10.5483/bmbrep.2022-0211 · 2023 · External reference
Dihydro-resveratrol attenuates oxidative stress, adipogenesis and insulin resistance in in vitro models and high-fat diet-induced mouse model via AMPK activation
10.3390/nu15133006 · 2023 · External reference
3D-QSAR and molecular docking studies of aminopyrimidine derivatives as novel three-targeted Lck/Src/KDR inhibitors
10.1016/j.molstruc.2019.02.071 · 2019 · External reference
Latexin deficiency attenuates adipocyte differentiation and protects mice against obesity and metabolic disorders induced by high-fat diet
10.1038/s41419-022-04636-9 · 2022 · External reference
Chapter 6 - caffeic acid phenethyl ester (CAPE): an active component of propolis: a review on its therapeutic potentials
10.1016/b978-0-443-22214-6.00008-9 · 2024 · External reference
Caffeic acid phenethyl ester inhibits basal lipolysis by activating PPAR-gamma and increasing lipid droplet-associated perilipin in mature rat adipocytes
10.1155/2022/6007233 · 2022 · External reference
Caffeic acid phenethyl ester inhibits differentiation to adipocytes in 3T3-L1 mouse fibroblasts
10.1248/bpb.33.1484 · 2010 · External reference
Caffeic acid phenethyl ester suppresses the production of adipocytokines, leptin, tumor necrosis factor -alpha and resistin, during differentiation to adipocytes in 3T3-L1 cells
10.1248/bpb.34.490 · 2011 · External reference
AMP-activated protein kinase: an energy sensor that regulates all aspects of cell function
10.1101/gad.17420111 · 2011 · External reference
Equisetin inhibits adiposity through AMPK-dependent regulation of brown adipocyte differentiation
10.1016/j.heliyon.2024.e25458 · 2024 · External reference
L-Fucose suppresses lipid accumulation via the AMPK pathway in 3T3-L1 adipocytes
10.3390/nu15030503 · 2023 · External reference
Targeting adipocyte differentiation with CRT0066101: activation of AMPK signaling in 3T3-L1 cells
10.3389/fphar.2025.1645587 · 2025 · External reference
Ursolic acid inhibits adipogenesis in 3T3-L1 adipocytes through LKB1/AMPK pathway
10.1371/journal.pone.0070135 · 2013 · External reference
Inhibition effect of adipogenesis and lipogenesis via activation of AMPK in preadipocytes treated with Canavalia gladiata extract
10.3390/ijms24032108 · 2023 · External reference
Role of AMP-activated protein kinase in mechanism of metformin action
10.1172/jci13505 · 2001 · External reference
Dorsomorphin inhibits AMPK, upregulates Wnt and Foxo genes and promotes the activation of dormant follicles
10.1038/s42003-024-06418-9 · 2024 · External reference
AMPK inhibition sensitizes acute leukemia cells to BH3 mimetic-induced cell death
10.1038/s41418-024-01283-9 · 2024 · External reference
Galactose-NlGr11 inhibits AMPK phosphorylation by activating the PI3K-AKT-PKF-ATP signaling cascade via insulin receptor and Gβγ
10.1111/1744-7917.12795 · 2021 · External reference
Metabolomics reveals that chronic restraint stress alleviates carbon tetrachloride-induced hepatic fibrosis through the INSR/PI3K/AKT/AMPK pathway
10.1007/s00109-023-02395-4 · 2024 · External reference
CAPE activates AMPK and Foxo3 signaling to induce growth inhibition and ferroptosis in triple-negative breast cancer
10.1371/journal.pone.0315037 · 2024 · External reference
CAPE (caffeic acid phenethyl ester) stimulates glucose uptake through AMPK (AMP-activated protein kinase) activation in skeletal muscle cells
10.1016/j.bbrc.2007.07.068 · 2007 · External reference
A guide to the Simulium damnosum complex (Diptera: Simuliidae) in Nigeria, with a cytotaxonomic key for the identification of the sibling species
10.1179/136485911x12987676649700 · 2011 · External reference
Differential roles of insulin and IGF-1 receptors in adipose tissue development and function
10.2337/db16-0212 · 2016 · External reference
Insulin signaling in Alzheimer's disease: association with brain insulin resistance
10.3390/ijms27031222 · 2026 · External reference
The insulin signalling network
10.1038/s42255-025-01349-z · 2025 · External reference
Phosphorylation by Akt within the ST loop of AMPK-α1 down-regulates its activation in tumour cells
10.1042/bj20131344 · 2014 · External reference
Accumulation of succinate controls activation of adipose tissue thermogenesis
10.1038/s41586-018-0353-2 · 2018 · External reference
Folate supplementation modifies CCAAT/enhancer-binding protein alpha methylation to mediate differentiation of preadipocytes in chickens
10.3382/ps.2014-04027 · 2014 · External reference