Research graph
References from The development of BioID: A tool for proximity proteomics in living cells. Local targets link to admitted publications; unresolved targets remain external evidence.
Illuminating the dark protein-protein interactome
2022 · External reference
Affinity-purification coupled to mass spectrometry: basic principles and strategies
10.1002/pmic.201100523 · 2012 · External reference
Dual proteome-scale networks reveal cell-specific remodeling of the human interactome
10.1016/j.cell.2021.04.011 · 2021 · External reference
A reference map of the human binary protein interactome
10.1038/s41586-020-2188-x · 2020 · External reference
Transient protein-protein interactions
10.1093/protein/gzr025 · 2011 · External reference
Meet the neighbors: mapping local protein interactomes by proximity-dependent labeling with BioID
10.1002/pmic.201600123 · 2016 · External reference
Protein interaction network of the mammalian hippo pathway reveals mechanisms of kinase-phosphatase interactions
10.1126/scisignal.2004712 · 2013 · External reference
Improving yeast two-hybrid screening systems
10.1093/bfgp/elm035 · 2008 · External reference
A proximity-dependent biotinylation map of a human cell
10.1038/s41586-021-03592-2 · 2021 · External reference
The development of proximity labeling technology and its applications in mammals, plants, and microorganisms
10.1186/s12964-023-01310-1 · 2023 · External reference
Proximity dependent biotinylation: key enzymes and adaptation to proteomics approaches
10.1074/mcp.r120.001941 · 2020 · External reference
A promiscuous biotin ligase fusion protein identifies proximal and interacting proteins in mammalian cells
10.1083/jcb.201112098 · 2012 · External reference
An improved smaller biotin ligase for BioID proximity labeling
10.1091/mbc.e15-12-0844 · 2016 · External reference
In planta proximity dependent biotin identification (BioID)
10.1038/s41598-018-27500-3 · 2018 · External reference
Screening of proximal and interacting proteins in rice protoplasts by proximity-dependent biotinylation
10.3389/fpls.2017.00749 · 2017 · External reference
Proximity-dependent biotin identification (BioID) in Dictyostelium amoebae
2016 · External reference
Novel components of the Toxoplasma inner membrane complex revealed by BioID
10.1128/mbio.02357-14 · 2015 · External reference
Capturing the Asc1p/receptor for activated C kinase 1 (RACK1) microenvironment at the head region of the 40S ribosome with quantitative BioID in yeast
10.1074/mcp.m116.066654 · 2017 · External reference
Proximity-dependent biotinylation by TurboID to identify protein-protein interaction networks in yeast
10.1242/jcs.232249 · 2019 · External reference
Efficient proximity labeling in living cells and organisms with TurboID
10.1038/nbt.4201 · 2018 · External reference
Highly effective proximate labeling in Drosophila
2021 · External reference
Interactome analysis of Caenorhabditis elegans synapses by TurboID-based proximity labeling
10.1016/j.jbc.2021.101094 · 2021 · External reference
A toolbox for efficient proximity-dependent Biotinylation in zebrafish embryos
10.1016/j.mcpro.2021.100128 · 2021 · External reference
In vivo proteomic mapping through GFP-directed proximity-dependent biotin labelling in zebrafish
10.7554/elife.64631 · 2021 · External reference
Deconstructing sarcomeric structure–function relations in titin-BioID knock-in mice
10.1038/s41467-020-16929-8 · 2020 · External reference
In vivo proximity proteomics of nascent synapses reveals a novel regulator of cytoskeleton-mediated synaptic maturation
10.1038/s41467-019-08288-w · 2019 · External reference
Claudin-4 localization in epithelial ovarian cancer
10.1016/j.heliyon.2022.e10862 · 2022 · External reference
Protein proximity networks and functional evaluation of the casein kinase 1 gamma family reveal unique roles for CK1γ3 in WNT signaling
10.1016/j.jbc.2022.101986 · 2022 · External reference
A BioID-derived proximity interactome for SARS-CoV-2 proteins
10.3390/v14030611 · 2022 · External reference
Proteomic analysis of the plasmodium berghei gametocyte egressome and vesicular bioID of osmiophilic body proteins identifies Merozoite TRAP-like protein (MTRAP) as an essential factor for parasite transmission
10.1074/mcp.m116.058263 · 2016 · External reference
In vivo biotinylation of the Toxoplasma parasitophorous vacuole reveals novel dense granule proteins important for parasite growth and pathogenesis
10.1128/mbio.00808-16 · 2016 · External reference
Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies
10.1016/j.celrep.2022.111678 · 2022 · External reference
A proximity biotinylation-based approach to identify protein-E3 ligase interactions induced by PROTACs and molecular glues
10.1038/s41467-021-27818-z · 2022 · External reference
Rice vitamins
2019 · External reference
Mechanisms governing precise protein biotinylation
10.1016/j.tibs.2017.02.001 · 2017 · External reference
Structure and function of biotin-dependent carboxylases
10.1007/s00018-012-1096-0 · 2013 · External reference
Structural and functional studies of the biotin protein ligase from Aquifex aeolicus reveal a critical role for a conserved residue in target specificity
10.1016/j.jmb.2008.12.086 · 2009 · External reference
Ligand specificity of group I biotin protein ligase of Mycobacterium tuberculosis
10.1371/journal.pone.0002320 · 2008 · External reference
Crystal structures of biotin protein ligase from Pyrococcus horikoshii OT3 and its complexes: structural basis of biotin activation
10.1016/j.jmb.2005.08.032 · 2005 · External reference
Nucleotide sequence of the birA gene encoding the biotin operon represser and biotin holoenzyme synthetase functions of Escherichia coli
10.1016/0378-1119(85)90011-3 · 1985 · External reference
The atypical occurrence of two biotin protein ligases in Francisella novicida is due to distinct roles in virulence and biotin metabolism
10.1128/mbio.00591-15 · 2015 · External reference
Structural characterization of Staphylococcus aureus biotin protein ligase and interaction partners: an antibiotic target
10.1002/pro.2262 · 2013 · External reference
Cloning and characterization of the Bacillus subtilis birA gene encoding a repressor of the biotin operon
10.1128/jb.177.9.2572-2575.1995 · 1995 · External reference
Molecular biology of biotin attachment to proteins
10.1093/jn/129.2.477s · 1999 · External reference
Mutational analysis of protein substrate presentation in the post-translational attachment of biotin to biotin domains
10.1074/jbc.m003968200 · 2001 · External reference
Corepressor-induced organization and assembly of the biotin repressor: a model for allosteric activation of a transcriptional regulator
10.1073/pnas.111128198 · 2001 · External reference
Co-repressor induced order and biotin repressor dimerization: a case for divergent followed by convergent evolution
10.1016/j.jmb.2005.12.066 · 2006 · External reference
The enzymatic synthesis of holotranscarboxylase from apotranscarboxylase and (+)-biotin
10.1016/s0021-9258(18)93826-3 · 1964 · External reference
Acetyl-CoA carboxylase from Escherichia coli exhibits a pronounced hysteresis when inhibited by palmitoyl-acyl carrier protein
10.1016/j.abb.2017.10.016 · 2017 · External reference
Multi-subunit acetyl-CoA carboxylases
10.1016/s0163-7827(02)00007-3 · 2002 · External reference
Biotination of proteins in vivo. A post-translational modification to label, purify, and study proteins
10.1016/s0021-9258(18)86949-6 · 1990 · External reference
Isolation of a cDNA encoding human holocarboxylase synthetase by functional complementation of a biotin auxotroph of Escherichia coli
10.1073/pnas.92.10.4626 · 1995 · External reference
Substrate specificity of archaeon Sulfolobus tokodaii biotin protein ligase
10.1016/j.bbrc.2006.03.118 · 2006 · External reference
A unique biotin carboxyl carrier protein in archaeon Sulfolobus tokodaii
10.1016/j.febslet.2006.01.083 · 2006 · External reference
Use of peptide libraries to map the substrate specificity of a peptide-modifying enzyme: a 13 residue consensus peptide specifies biotinylation in Escherichia coli
10.1038/nbt1093-1138 · 1993 · External reference
A minimal peptide substrate in biotin holoenzyme synthetase-catalyzed biotinylation
10.1110/ps.8.4.921 · 1999 · External reference
Protein−protein interaction detection in vitro and in cells by proximity biotinylation
10.1021/ja801445p · 2008 · External reference
The switch regulating transcription of the Escherichia coli biotin operon does not require extensive protein-protein interactions
10.1016/j.chembiol.2009.12.007 · 2010 · External reference
A mutant of Escherichia coli that requires high concentrations of biotin
10.1073/pnas.69.3.676 · 1972 · External reference
Use of bio-lac fusion strains to study regulation of biotin biosynthesis in Escherichia coli
10.1128/jb.143.2.789-800.1980 · 1980 · External reference
The birA gene of Escherichia coli encodes a biotin holoenzyme synthetase
10.1016/0022-2836(81)90042-5 · 1981 · External reference
DNA-binding and enzymatic domains of the bifunctional biotin operon repressor (BirA) of Escherichia
10.1016/0378-1119(86)90189-7 · 1986 · External reference
Function of a conserved sequence motif in biotin holoenzyme synthetases
10.1110/ps.9.8.1530 · 2000 · External reference
Competing protein:protein interactions are proposed to control the biological switch of the E coli biotin repressor
10.1110/ps.32701 · 2001 · External reference
Multiple disordered loops function in corepressor-induced dimerization of the biotin repressor
10.1006/jmbi.2000.4249 · 2000 · External reference
Promiscuous protein biotinylation by Escherichia coli biotin protein ligase
10.1110/ps.04911804 · 2004 · External reference
10.1073/pnas.1406459111
10.1073/pnas.1406459111 · External reference
Getting to know the neighborhood: using proximity-dependent biotinylation to characterize protein complexes and map organelles
10.1016/j.cbpa.2018.10.017 · 2019 · External reference
In vivo identification of GTPase interactors by mitochondrial relocalization and proximity biotinylation
10.7554/elife.45916 · 2019 · External reference
Protein neighbors and proximity proteomics
10.1074/mcp.r115.052902 · 2015 · External reference
Recent advances in proximity-based labeling methods for interactome mapping
10.12688/f1000research.16903.1 · 2019 · External reference
Interaction network of human early embryonic transcription factors
10.1038/s44319-024-00074-0 · 2024 · External reference
Human transcription factor protein interaction networks
10.1038/s41467-022-28341-5 · 2022 · External reference
Nuclear factor I family members are key transcription factors regulating gene expression
10.1016/j.mcpro.2024.100890 · 2025 · External reference
Identification of in vivo DNA targets of chromatin proteins using tethered Dam methyltransferase
10.1038/74487 · 2000 · External reference
Proximity interactions among centrosome components identify regulators of centriole duplication
10.1016/j.cub.2014.01.067 · 2014 · External reference
Proximity-dependent biotinylation (BioID) of integrin interaction partners
2021 · External reference
Proteomic analysis of proteins surrounding Occludin and Claudin-4 reveals their proximity to signaling and trafficking networks
10.1371/journal.pone.0117074 · 2015 · External reference
High-density proximity mapping reveals the subcellular organization of mRNA-associated granules and bodies
10.1016/j.molcel.2017.12.020 · 2018 · External reference
Proximity biotinylation identifies a set of conformation-specific interactions between Merlin and cell junction proteins
10.1126/scisignal.aau8749 · 2019 · External reference
Proximity-dependent biotinylation approaches to explore the dynamic compartmentalized proteome
10.3389/fmolb.2022.852911 · 2022 · External reference
Subcellular proteomics
10.1038/s43586-021-00029-y · 2021 · External reference
Interactomes of glycogen synthase Kinase-3 isoforms
10.1021/acs.jproteome.2c00825 · 2023 · External reference
Comparative application of BioID and TurboID for protein-proximity biotinylation
10.3390/cells9051070 · 2020 · External reference
RNA–protein interaction detection in living cells
10.1038/nmeth.4601 · 2018 · External reference
AirID, a novel proximity biotinylation enzyme, for analysis of protein–protein interactions
10.7554/elife.54983 · 2020 · External reference
Engineering of ultraID, a compact and hyperactive enzyme for proximity-dependent biotinylation in living cells
10.1038/s42003-022-03604-5 · 2022 · External reference
MicroID2: a novel biotin ligase enables rapid proximity-dependent proteomics
10.1016/j.mcpro.2022.100256 · 2022 · External reference
Novel bilobe components in Trypanosoma brucei identified using proximity-dependent biotinylation
10.1128/ec.00326-12 · 2013 · External reference
BioID reveals novel proteins of the Plasmodium parasitophorous vacuole membrane
10.1128/msphere.00522-17 · 2018 · External reference
Benchmarking of proximity-dependent biotinylation enzymes across cellular compartments and time windows
2025 · External reference
In vivo proximity labeling identifies cardiomyocyte protein networks during zebrafish heart regeneration
10.7554/elife.66079 · 2021 · External reference
Characterization of BioID tagging systems in budding yeast and exploring the interactome of the Ccr4-not complex
10.1093/g3journal/jkae221 · 2024 · External reference
TurboID-based proximity labeling reveals that UBR7 is a regulator of N NLR immune receptor-mediated immunity
10.1038/s41467-019-11202-z · 2019 · External reference
Proximity labeling of protein complexes and cell-type-specific organellar proteomes in Arabidopsis enabled by TurboID
10.7554/elife.47864 · 2019 · External reference
AirID-based proximity labeling for protein-protein interaction in plants
10.3791/64428 · 2022 · External reference
Unresolved reference
2024 · External reference
Diffusion and retention are major determinants of protein targeting to the inner nuclear membrane
10.1083/jcb.201409127 · 2015 · External reference
10.4161/nucl.2.2.14637 · 2011 · Admitted local publication
Deciphering molecular interactions by proximity labeling
10.1038/s41592-020-01010-5 · 2021 · External reference
Filling the void: proximity-based labeling of proteins in living cells
10.1016/j.tcb.2016.09.004 · 2016 · External reference
Split-BioID: a proximity biotinylation assay for dimerization-dependent protein interactions
10.1002/1873-3468.12548 · 2017 · External reference
Context-specific and proximity-dependent labeling for the proteomic analysis of spatiotemporally defined protein complexes with Split-BioID
2021 · External reference
Split-BioID a conditional proteomics approach to monitor the composition of spatiotemporally defined protein complexes
10.1038/ncomms15690 · 2017 · External reference
Insights into RNA biology from an atlas of mammalian mRNA-binding proteins
10.1016/j.cell.2012.04.031 · 2012 · External reference
The STAT3-binding long noncoding RNA lnc-DC controls human dendritic cell differentiation
10.1126/science.1251456 · 2014 · External reference
Evidence for reassociation of RNA-binding proteins after cell lysis: implications for the interpretation of immunoprecipitation analyses
10.1261/rna.7151404 · 2004 · External reference
Successful conversion of the Bacillus subtilis BirA group II biotin protein ligase into a group I ligase
10.1371/journal.pone.0096757 · 2014 · External reference
Evidence for Interdomain interaction in the Escherichia coli repressor of biotin biosynthesis from studies of an N-terminal domain deletion mutant
10.1021/bi952269e · 1996 · External reference
The wing of a winged Helix-turn-helix transcription factor organizes the active site of BirA, a bifunctional repressor/ligase
10.1074/jbc.m113.525618 · 2013 · External reference
RNA-protein interaction analysis of SARS-CoV-2 5′ and 3′ untranslated regions reveals a role of lysosome-associated membrane protein-2a during viral infection
10.1128/msystems.00643-21 · 2021 · External reference
ChromID identifies the protein interactome at chromatin marks
10.1038/s41587-020-0434-2 · 2020 · External reference
A novel class of ER membrane proteins regulates ER-associated endosome fission
10.1016/j.cell.2018.08.030 · 2018 · External reference
Proximity labeling in mammalian cells with TurboID and split-TurboID
10.1038/s41596-020-0399-0 · 2020 · External reference
In vivo profiling of the Alk Proximitome in the developing Drosophila brain
10.1016/j.jmb.2021.167282 · 2021 · External reference
Identifying protein-protein interactions by proximity Biotinylation with AirID and splitAirID
10.1002/cpz1.702 · 2023 · External reference
When less is more – a fast TurboID knock-in approach for high-sensitivity endogenous interactome mapping
10.1242/jcs.261952 · 2024 · External reference
Integrating endogenous TurboID and data-independent acquisition mass spectrometry for in vivo proximity labeling
10.1038/s44318-025-00660-5 · 2025 · External reference
BioID: a screen for protein-protein interactions
2018 · External reference
Proximity biotinylation and affinity purification are complementary approaches for the interactome mapping of chromatin-associated protein complexes
10.1016/j.jprot.2014.09.011 · 2015 · External reference
The CRAPome: a contaminant repository for affinity purification–mass spectrometry data
10.1038/nmeth.2557 · 2013 · External reference
Control of TurboID-dependent biotinylation intensity in proximity ligation screens
10.1016/j.jprot.2023.104886 · 2023 · External reference
Structural origins of high-affinity biotin binding to streptavidin
10.1126/science.2911722 · 1989 · External reference
Antibodies to biotin enable large-scale detection of biotinylation sites on proteins
10.1038/nmeth.4465 · 2017 · External reference
BioSITe: a method for direct detection and quantitation of site-specific biotinylation
10.1021/acs.jproteome.7b00775 · 2018 · External reference
Directed evolution of the substrate specificity of biotin ligase
10.1002/bit.25176 · 2014 · External reference
Thiol-cleavable biotin for chemical and enzymatic biotinylation and its application to mitochondrial TurboID proteomics
10.1021/jasms.1c00079 · 2021 · External reference
Comparing SILAC- and stable isotope dimethyl-labeling approaches for quantitative proteomics
10.1021/pr500630a · 2014 · External reference
Overcoming analytical challenges in proximity labeling proteomics
10.1002/jms.5134 · 2025 · External reference
SAINTexpress: improvements and additional features in significance analysis of INTeractome software
10.1016/j.jprot.2013.10.023 · 2014 · External reference
SAINT: probabilistic scoring of affinity purification–mass spectrometry data
10.1038/nmeth.1541 · 2011 · External reference
SAINTq: scoring protein-protein interactions in affinity purification – mass spectrometry experiments with fragment or peptide intensity data
10.1002/pmic.201500499 · 2016 · External reference
ProHits-viz: a suite of web tools for visualizing interaction proteomics data
10.1038/nmeth.4330 · 2017 · External reference
Combined proximity labeling and affinity purification−mass spectrometry workflow for mapping and visualizing protein interaction networks
10.1038/s41596-020-0365-x · 2020 · External reference
An AP-MS- and BioID-compatible MAC-tag enables comprehensive mapping of protein interactions and subcellular localizations
10.1038/s41467-018-03523-2 · 2018 · External reference
Proximity ligation assay for detecting protein-protein interactions and protein modifications in cells and tissues in situ
10.1002/cpcb.115 · 2020 · External reference
Luciferase complementation for cellular assays beyond protein–protein interactions
10.1007/s44211-025-00730-y · 2025 · External reference
