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References from The role of CD4+ T cell differentiation in cytomegalovirus-associated parahippocampal volume reduction and depressive symptoms: a dual-sample study. Local targets link to admitted publications; unresolved targets remain external evidence.
Purine metabolism is dysregulated in patients with major depressive disorder
10.1016/j.psyneuen.2016.04.017 · 2016 · External reference
Cytomegalovirus infection associated with smaller dentate gyrus in men with severe mental illness
10.1016/j.bbi.2021.05.009 · 2021 · External reference
Cytomegalovirus infection associated with smaller total cortical surface area in Schizophrenia spectrum disorders
10.1093/schbul/sbac036 · 2022 · External reference
The bidirectional relationship of depression and inflammation: double trouble
10.1016/j.neuron.2020.06.002 · 2020 · External reference
Variation in the human immune system is largely driven by non-heritable influences
10.1016/j.cell.2014.12.020 · 2015 · External reference
Large-scale study of Toxoplasma and Cytomegalovirus shows an association between infection and serious psychiatric disorders
10.1016/j.bbi.2019.01.026 · 2019 · External reference
Validation of FreeSurfer-estimated brain cortical thickness: comparison with histologic measurements
10.1007/s12021-014-9229-2 · 2014 · External reference
Cortical surface-based analysis. I. Segmentation and Surface Reconstruction
10.1006/nimg.1998.0395 · 1999 · External reference
From inflammation to sickness and depression: when the immune system subjugates the brain
10.1038/nrn2297 · 2008 · External reference
Interaction between the amygdala and the medial temporal lobe memory system predicts better memory for emotional events
10.1016/s0896-6273(04)00289-2 · 2004 · External reference
Unresolved reference
External reference
A natural experiment on the effect of herpes zoster vaccination on dementia
10.1038/s41586-025-08800-x · 2025 · External reference
Stress-induced metabolic disorder in peripheral CD4(+) T cells leads to anxiety-like behavior
2019 · External reference
Diagnosis-independent loss of T-cell costimulatory molecules in individuals with cytomegalovirus infection
10.1016/j.bbi.2020.03.013 · 2020 · External reference
Reduced immunity to measles in adults with major depressive disorder
10.1017/s0033291718000661 · 2019 · External reference
Microglia activation orchestrates CXCL10-mediated CD8(+) T cell recruitment to promote aging-related white matter degeneration
10.1038/s41593-025-01955-w · 2025 · External reference
Accumulation of cytotoxic T cells in the aged CNS leads to axon degeneration and contributes to cognitive and motor decline
10.1038/s43587-021-00049-z · 2021 · External reference
Time for united action on depression: a lancet-world psychiatric association commission
10.1016/s0140-6736(21)02141-3 · 2022 · External reference
Cytomegalovirus seropositivity and serointensity are associated with hippocampal volume and verbal memory in schizophrenia and bipolar disorder
10.1016/j.pnpbp.2013.09.003 · 2014 · External reference
Inflammation and depressive phenotypes: evidence from medical records from over 12 000 patients and brain morphology
10.1017/s0033291719002940 · 2020 · External reference
Test-retest reliability of freesurfer measurements within and between sites: effects of visual approval process
10.1002/hbm.22856 · 2015 · External reference
CD8(+) T cells induce interferon-responsive oligodendrocytes and microglia in white matter aging
10.1038/s41593-022-01183-6 · 2022 · External reference
CD4+CD25+ regulatory T cell depletion modulates anxiety and depression-like behaviors in mice
2012 · External reference
T cell responses to cytomegalovirus
10.1038/nri.2016.38 · 2016 · External reference
Social stressors associated with age-related T lymphocyte percentages in older US adults: evidence from the US Health and Retirement Study
10.1073/pnas.2202780119 · 2022 · External reference
IL-1beta is an essential mediator of the antineurogenic and anhedonic effects of stress
10.1073/pnas.0708092105 · 2008 · External reference
Genetic variants associated with psychiatric disorders are enriched at epigenetically active sites in lymphoid cells
10.1038/s41467-022-33885-7 · 2022 · External reference
Peripheral Blood Cell-Stratified Subgroups of Inflamed Depression
10.1016/j.biopsych.2019.11.017 · 2020 · External reference
Standardizing immunophenotyping for the human immunology project
10.1038/nri3158 · 2012 · External reference
The role of inflammation in depression: from evolutionary imperative to modern treatment target
10.1038/nri.2015.5 · 2016 · External reference
Inflammatory blockade restores adult hippocampal neurogenesis
10.1126/science.1088417 · 2003 · External reference
Primary immune responses are negatively impacted by persistent herpesvirus infections in older people: results from an observational study on healthy subjects and a vaccination trial on subjects aged more than 70 years old
10.1016/j.ebiom.2022.103852 · 2022 · External reference
The Enigmatic temporal pole: a review of findings on social and emotional processing
10.1093/brain/awm052 · 2007 · External reference
T cell activation and deficits in T regulatory cells are associated with major depressive disorder and severity of depression
10.1038/s41598-024-61865-y · 2024 · External reference
The CES-D scale: a self-report depression scale for research in the general population
10.1177/014662167700100306 · 1977 · External reference
CD4+ but not CD8+ T cells revert the impaired emotional behavior of immunocompromised RAG-1-deficient mice
10.1038/tp.2013.54 · 2013 · External reference
Putative neuroprotective and neurotoxic kynurenine pathway metabolites are associated with hippocampal and amygdalar volumes in subjects with major depressive disorder
10.1038/npp.2014.194 · 2015 · External reference
Cohort profile: the health and retirement study (HRS)
10.1093/ije/dyu067 · 2014 · External reference
10.7826/isr-um.06.585031.001.05.0005.2000
10.7826/isr-um.06.585031.001.05.0005.2000 · External reference
Broadly targeted human cytomegalovirus-specific CD4+ and CD8+ T cells dominate the memory compartments of exposed subjects
10.1084/jem.20050882 · 2005 · External reference
The recombinant shingles vaccine is associated with lower risk of dementia
10.1038/s41591-024-03201-5 · 2024 · External reference
Unresolved reference
External reference
CD4-positive T lymphocytes provide a neuroimmunological link in the control of adult hippocampal neurogenesis
10.4049/jimmunol.0801218 · 2009 · External reference
The indirect effects of cytomegalovirus infection-mechanisms and consequences
10.1098/rstb.2024.0398 · 2025 · External reference
Replicable association between human cytomegalovirus infection and reduced white matter fractional anisotropy in major depressive disorder
10.1038/s41386-021-00971-1 · 2021 · External reference
A hidden menace? Cytomegalovirus infection is associated with reduced cortical gray matter volume in major depressive disorder
10.1038/s41380-020-00932-y · 2020 · External reference
Association between cytomegalovirus infection, reduced gray matter volume, and resting-state functional hypoconnectivity in major depressive disorder: a replication and extension
10.1038/s41398-021-01558-6 · 2021 · External reference
Effect of cytomegalovirus infection on the central nervous system: implications for psychiatric disorders
10.1007/7854_2022_361 · 2022 · External reference
Herpesviruses and neuropsychiatric disorders: overlooked adversaries or innocent bystanders?
10.1038/s41386-023-01674-5 · 2023 · External reference
Cytomegalovirus antibodies are associated with mood disorders, suicide, markers of neuroinflammation, and microglia activation in postmortem brain samples
10.1038/s41380-023-02162-4 · 2023 · External reference
Estimation of the worldwide seroprevalence of cytomegalovirus: a systematic review and meta-analysis
10.1002/rmv.2034 · 2019 · External reference
Test-retest reliability of freesurfer measurements within and between sites: effects of visual approval process
10.1002/hbm.22856 · ExternalCitation · doi-reference
Estimation of the worldwide seroprevalence of cytomegalovirus: a systematic review and meta-analysis
10.1002/rmv.2034 · ExternalCitation · doi-reference
Cortical surface-based analysis. I. Segmentation and Surface Reconstruction
10.1006/nimg.1998.0395 · ExternalCitation · doi-reference
Effect of cytomegalovirus infection on the central nervous system: implications for psychiatric disorders
10.1007/7854_2022_361 · ExternalCitation · doi-reference
Validation of FreeSurfer-estimated brain cortical thickness: comparison with histologic measurements
10.1007/s12021-014-9229-2 · ExternalCitation · doi-reference
Large-scale study of Toxoplasma and Cytomegalovirus shows an association between infection and serious psychiatric disorders
10.1016/j.bbi.2019.01.026 · ExternalCitation · doi-reference
Diagnosis-independent loss of T-cell costimulatory molecules in individuals with cytomegalovirus infection
10.1016/j.bbi.2020.03.013 · ExternalCitation · doi-reference
Cytomegalovirus infection associated with smaller dentate gyrus in men with severe mental illness
10.1016/j.bbi.2021.05.009 · ExternalCitation · doi-reference
Peripheral Blood Cell-Stratified Subgroups of Inflamed Depression
10.1016/j.biopsych.2019.11.017 · ExternalCitation · doi-reference
Variation in the human immune system is largely driven by non-heritable influences
10.1016/j.cell.2014.12.020 · ExternalCitation · doi-reference
Primary immune responses are negatively impacted by persistent herpesvirus infections in older people: results from an observational study on healthy subjects and a vaccination trial on subjects aged more than 70 years old
10.1016/j.ebiom.2022.103852 · ExternalCitation · doi-reference
The bidirectional relationship of depression and inflammation: double trouble
10.1016/j.neuron.2020.06.002 · ExternalCitation · doi-reference
Cytomegalovirus seropositivity and serointensity are associated with hippocampal volume and verbal memory in schizophrenia and bipolar disorder
10.1016/j.pnpbp.2013.09.003 · ExternalCitation · doi-reference
Purine metabolism is dysregulated in patients with major depressive disorder
10.1016/j.psyneuen.2016.04.017 · ExternalCitation · doi-reference
Time for united action on depression: a lancet-world psychiatric association commission
10.1016/s0140-6736(21)02141-3 · ExternalCitation · doi-reference
Interaction between the amygdala and the medial temporal lobe memory system predicts better memory for emotional events
10.1016/s0896-6273(04)00289-2 · ExternalCitation · doi-reference
Reduced immunity to measles in adults with major depressive disorder
10.1017/s0033291718000661 · ExternalCitation · doi-reference
Inflammation and depressive phenotypes: evidence from medical records from over 12 000 patients and brain morphology
10.1017/s0033291719002940 · ExternalCitation · doi-reference
Putative neuroprotective and neurotoxic kynurenine pathway metabolites are associated with hippocampal and amygdalar volumes in subjects with major depressive disorder
10.1038/npp.2014.194 · ExternalCitation · doi-reference
The role of inflammation in depression: from evolutionary imperative to modern treatment target
10.1038/nri.2015.5 · ExternalCitation · doi-reference
T cell responses to cytomegalovirus
10.1038/nri.2016.38 · ExternalCitation · doi-reference
Standardizing immunophenotyping for the human immunology project
10.1038/nri3158 · ExternalCitation · doi-reference
From inflammation to sickness and depression: when the immune system subjugates the brain
10.1038/nrn2297 · ExternalCitation · doi-reference
A hidden menace? Cytomegalovirus infection is associated with reduced cortical gray matter volume in major depressive disorder
10.1038/s41380-020-00932-y · ExternalCitation · doi-reference
Cytomegalovirus antibodies are associated with mood disorders, suicide, markers of neuroinflammation, and microglia activation in postmortem brain samples
10.1038/s41380-023-02162-4 · ExternalCitation · doi-reference
Replicable association between human cytomegalovirus infection and reduced white matter fractional anisotropy in major depressive disorder
10.1038/s41386-021-00971-1 · ExternalCitation · doi-reference
Herpesviruses and neuropsychiatric disorders: overlooked adversaries or innocent bystanders?
10.1038/s41386-023-01674-5 · ExternalCitation · doi-reference
Association between cytomegalovirus infection, reduced gray matter volume, and resting-state functional hypoconnectivity in major depressive disorder: a replication and extension
10.1038/s41398-021-01558-6 · ExternalCitation · doi-reference
Genetic variants associated with psychiatric disorders are enriched at epigenetically active sites in lymphoid cells
10.1038/s41467-022-33885-7 · ExternalCitation · doi-reference
A natural experiment on the effect of herpes zoster vaccination on dementia
10.1038/s41586-025-08800-x · ExternalCitation · doi-reference
The recombinant shingles vaccine is associated with lower risk of dementia
10.1038/s41591-024-03201-5 · ExternalCitation · doi-reference
CD8(+) T cells induce interferon-responsive oligodendrocytes and microglia in white matter aging
10.1038/s41593-022-01183-6 · ExternalCitation · doi-reference
Microglia activation orchestrates CXCL10-mediated CD8(+) T cell recruitment to promote aging-related white matter degeneration
10.1038/s41593-025-01955-w · ExternalCitation · doi-reference
T cell activation and deficits in T regulatory cells are associated with major depressive disorder and severity of depression
10.1038/s41598-024-61865-y · ExternalCitation · doi-reference
Accumulation of cytotoxic T cells in the aged CNS leads to axon degeneration and contributes to cognitive and motor decline
10.1038/s43587-021-00049-z · ExternalCitation · doi-reference
CD4+ but not CD8+ T cells revert the impaired emotional behavior of immunocompromised RAG-1-deficient mice
10.1038/tp.2013.54 · ExternalCitation · doi-reference
IL-1beta is an essential mediator of the antineurogenic and anhedonic effects of stress
10.1073/pnas.0708092105 · ExternalCitation · doi-reference
Social stressors associated with age-related T lymphocyte percentages in older US adults: evidence from the US Health and Retirement Study
10.1073/pnas.2202780119 · ExternalCitation · doi-reference
Broadly targeted human cytomegalovirus-specific CD4+ and CD8+ T cells dominate the memory compartments of exposed subjects
10.1084/jem.20050882 · ExternalCitation · doi-reference
The Enigmatic temporal pole: a review of findings on social and emotional processing
10.1093/brain/awm052 · ExternalCitation · doi-reference
Cohort profile: the health and retirement study (HRS)
10.1093/ije/dyu067 · ExternalCitation · doi-reference
Cytomegalovirus infection associated with smaller total cortical surface area in Schizophrenia spectrum disorders
10.1093/schbul/sbac036 · ExternalCitation · doi-reference
The indirect effects of cytomegalovirus infection-mechanisms and consequences
10.1098/rstb.2024.0398 · ExternalCitation · doi-reference
Inflammatory blockade restores adult hippocampal neurogenesis
10.1126/science.1088417 · ExternalCitation · doi-reference
The CES-D scale: a self-report depression scale for research in the general population
10.1177/014662167700100306 · ExternalCitation · doi-reference
CD4-positive T lymphocytes provide a neuroimmunological link in the control of adult hippocampal neurogenesis
10.4049/jimmunol.0801218 · ExternalCitation · doi-reference
10.7826/isr-um.06.585031.001.05.0005.2000
10.7826/isr-um.06.585031.001.05.0005.2000 · ExternalCitation · doi-reference