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References from Mitochondrial respiratory capacity modulates LPS-induced inflammatory signatures in human blood. Local targets link to admitted publications; unresolved targets remain external evidence.
Blood contains circulating cell-free respiratory competent mitochondria
10.1096/fj.201901917rr · 2020 · External reference
Transient 100 nM dexamethasone treatment reduces inter- and intraindividual variations in osteoblastic differentiation of bone marrow-derived human mesenchymal stem cells
10.1089/ten.tec.2011.0675 · 2012 · External reference
Immune-inflammatory pathways and clinical changes in fibromyalgia patients treated with Mindfulness-Based Stress Reduction (MBSR): a randomized, controlled clinical trial
10.1016/j.bbi.2019.02.030 · 2019 · External reference
Macrophage cytokines: involvement in immunity and infectious diseases
10.3389/fimmu.2014.00491 · 2014 · External reference
Sex differences in the neuro-immune consequences of stress: focus on depression and anxiety
10.1016/j.bbi.2017.02.006 · 2018 · External reference
Mitochondrial dysfunction prevents repolarization of inflammatory macrophages
10.1016/j.celrep.2016.09.008 · 2016 · External reference
The association between cortisol, oxytocin, and immune cell mitochondrial oxygen consumption in postpartum women with childhood maltreatment
10.1016/j.psyneuen.2018.05.040 · 2018 · External reference
Advances in the understanding of mitochondrial DNA as a pathogenic factor in inflammatory diseases
10.12688/f1000research.10397.1 · 2017 · External reference
Mitochondria as central hub of the immune system
10.1016/j.redox.2019.101255 · 2019 · External reference
Pretreatment of low-dose and super-low-dose LPS on the production of in vitro LPS-induced inflammatory mediators
10.5487/tr.2018.34.1.065 · 2018 · External reference
Evolution of mitochondria as signaling organelles
10.1016/j.cmet.2015.05.013 · 2015 · External reference
Metabolic coordination of T cell quiescence and activation
10.1038/s41577-019-0203-y · 2020 · External reference
CNS inflammation and neurodegeneration
10.1172/jci90609 · 2017 · External reference
Dynamic balance of pro- and anti-inflammatory signals controls disease and limits pathology
10.1111/imr.12671 · 2018 · External reference
Unresolved reference
1988 · External reference
Acute inflammatory response to endotoxin in mice and humans
2005 · External reference
Whole-blood culture is a valid low-cost method to measure monocytic cytokines - a comparison of cytokine production in cultures of human whole-blood, mononuclear cells and monocytes
10.1016/j.jim.2008.10.005 · 2009 · External reference
Dynamic regulation of mitochondrial function by glucocorticoids
10.1073/pnas.0812671106 · 2009 · External reference
Functional analysis via standardized whole-blood stimulation systems defines the boundaries of a healthy immune response to complex stimuli
10.1016/j.immuni.2014.03.002 · 2014 · External reference
Metabolic adaptations of CD4(+) T cells in inflammatory disease
10.3389/fimmu.2018.00540 · 2018 · External reference
Cell-permeable succinate prodrugs bypass mitochondrial complex I deficiency
10.1038/ncomms12317 · 2016 · External reference
Cause of death in children with mitochondrial diseases
10.1016/j.pediatrneurol.2016.10.006 · 2017 · External reference
Inflammageing: chronic inflammation in ageing, cardiovascular disease, and frailty
10.1038/s41569-018-0064-2 · 2018 · External reference
Fuel feeds function: energy metabolism and the T-cell response
10.1038/nri1710 · 2005 · External reference
Mitochondrial respiratory-chain adaptations in macrophages contribute to antibacterial host defense
10.1038/ni.3509 · 2016 · External reference
Measurement of fatigue in cancer patients: development and validation of the Fatigue Symptom Inventory
10.1023/a:1008842517972 · 1998 · External reference
Inflammation, metaflammation and immunometabolic disorders
10.1038/nature21363 · 2017 · External reference
Cell-intrinsic lysosomal lipolysis is essential for alternative activation of macrophages
10.1038/ni.2956 · 2014 · External reference
Impairment of mitochondrial respiration following ex vivo cyanide exposure in peripheral blood mononuclear cells
10.3109/15563650.2016.1139712 · 2016 · External reference
Development and pilot testing of a psychoeducational intervention for oral cancer patients
10.1002/pon.767 · 2004 · External reference
Mitochondrial membrane potential is required for MAVS-mediated antiviral signaling
10.1126/scisignal.2001147 · 2011 · External reference
Cytochrome c oxidase subunit IV is essential for assembly and respiratory function of the enzyme complex
10.1007/s10863-006-9052-z · 2006 · External reference
A functional genomics approach to understand variation in cytokine production in humans
10.1016/j.cell.2016.10.017 · 2016 · External reference
Increased plasma levels of circulating cell-free mitochondrial DNA in suicide attempters: associations with HPA-axis hyperactivity
10.1038/tp.2016.236 · 2016 · External reference
Circulating cell-free mitochondrial DNA, but not leukocyte mitochondrial DNA copy number, is elevated in major depressive disorder
10.1038/s41386-017-0001-9 · 2018 · External reference
High-dose IL-2 skews a glucocorticoid-driven IL-17(+)IL-10(+) memory CD4(+) T cell response towards a single IL-10-producing phenotype
10.4049/jimmunol.1800697 · 2019 · External reference
The effects of acute psychological stress on circulating and stimulated inflammatory markers: a systematic review and meta-analysis
10.1016/j.bbi.2017.01.011 · 2017 · External reference
Mitochondria: an organelle of bacterial origin controlling inflammation
10.3389/fimmu.2018.00536 · 2018 · External reference
Glucocorticoid receptor isoforms direct distinct mitochondrial programs to regulate ATP production
10.1038/srep26419 · 2016 · External reference
Post-traumatic growth and psychosocial adjustment of daughters of breast cancer survivors
10.1188/06.onf.543-551 · 2006 · External reference
Corticosterone production during repeated social defeat causes monocyte mobilization from the bone marrow, glucocorticoid resistance, and neurovascular adhesion molecule expression
10.1523/jneurosci.2568-17.2018 · 2018 · External reference
A cytokine protein-protein interaction network for identifying key molecules in rheumatoid arthritis
10.1371/journal.pone.0199530 · 2018 · External reference
Glucocorticoid resistance: is it a requisite for increased cytokine production in depression? A systematic review and meta-analysis
10.3389/fpsyt.2019.00423 · 2019 · External reference
Distinctive roles of age, sex, and genetics in shaping transcriptional variation of human immune responses to microbial challenges
10.1073/pnas.1714765115 · 2018 · External reference
A mitochondrial health index sensitive to mood and caregiving stress
10.1016/j.biopsych.2018.01.012 · 2018 · External reference
The immunopathology of sepsis and potential therapeutic targets
10.1038/nri.2017.36 · 2017 · External reference
Glucocorticoid receptor isoforms in human hepatocarcinoma HepG2 and SaOS-2 osteosarcoma cells: presence of glucocorticoid receptor alpha in mitochondria and of glucocorticoid receptor beta in nucleoli
10.1016/j.biocel.2005.06.015 · 2005 · External reference
Mitochondrial membrane potential in human neutrophils is maintained by complex III activity in the absence of supercomplex organisation
10.1371/journal.pone.0002013 · 2008 · External reference
Deciphering sex differences in the immune system and depression
10.1016/j.yfrne.2017.12.004 · 2018 · External reference
Age and age-related diseases: role of inflammation triggers and cytokines
10.3389/fimmu.2018.00586 · 2018 · External reference
Stimulation of systemic low-grade inflammation by psychosocial stress
10.1097/psy.0000000000000049 · 2014 · External reference
Aerobic exercise training and inducible inflammation- results of a randomized controlled trial in healthy, young adults
2018 · External reference
Existence of circulating mitochondria in human and animal peripheral blood
10.3390/ijms21062122 · 2020 · External reference
Stability of individual LPS-induced ex vivo cytokine release in a whole blood assay over a five-year interval
10.1016/j.jim.2018.06.018 · 2018 · External reference
Acute psychosocial stress induces differential short-term changes in catecholamine sensitivity of stimulated inflammatory cytokine production
10.1016/j.bbi.2014.07.014 · 2015 · External reference
Sex hormones determine immune response
10.3389/fimmu.2018.01931 · 2018 · External reference
Succinate is an inflammatory signal that induces IL-1β through HIF-1α
10.1038/nature11986 · 2013 · External reference
Cytochrome c oxidase activity is a metabolic checkpoint that regulates cell fate decisions during T cell activation and differentiation
10.1016/j.cmet.2017.05.007 · 2017 · External reference
Predictors of ccf-mtDNA reactivity to acute psychological stress identified using machine learning classifiers: a proof-of-concept
10.1016/j.psyneuen.2019.05.001 · 2019 · External reference
Acute psychological stress increases serum circulating cell-free mitochondrial DNA
10.1016/j.psyneuen.2019.03.026 · 2019 · External reference
Mitochondria: a central target for sex differences in pathologies
10.1042/cs20160485 · 2017 · External reference
Development of glucocorticoid resistance over one year among mothers of children newly diagnosed with cancer
10.1016/j.bbi.2017.12.011 · 2018 · External reference
Mitochondria in the regulation of innate and adaptive immunity
10.1016/j.immuni.2015.02.002 · 2015 · External reference
Mitochondrial Dysfunction Is Associated with an Immune Paralysis Phenotype in Pediatric Sepsis
2019 · External reference
Mitochondria in innate immune responses
10.1038/nri2975 · 2011 · External reference
Inhibition of neuronal cell mitochondrial complex I with rotenone increases lipid beta-oxidation, supporting acetyl-coenzyme A levels
10.1074/jbc.m114.591354 · 2014 · External reference
Identification of high and low responders to lipopolysaccharide in normal subjects: an unbiased approach to identify modulators of innate immunity
10.4049/jimmunol.175.4.2570 · 2005 · External reference
Using MetaboAnalyst 3.0 for comprehensive metabolomics data analysis
10.1002/cpbi.11 · 2016 · External reference
COX5B regulates MAVS-mediated antiviral signaling through interaction with ATG5 and repressing ROS production
10.1371/journal.ppat.1003086 · 2012 · External reference