Research graph
References from PIST couples actin cytoskeleton dynamics through a WH2-like actin-binding domain. Local targets link to admitted publications; unresolved targets remain external evidence.
Molecular mechanism of parallel fiber-Purkinje cell synapse formation
2012 · External reference
Glutamate-Receptor-Like molecule GluRδ2 involved in synapse Formation at parallel fiber-purkinje neuron synapses
10.1007/s12311-010-0170-0 · 2012 · External reference
Differential regulation of synaptic plasticity and cerebellar motor learning by the C-Terminal PDZ-Binding motif of GluRδ2
10.1523/jneurosci.2553-07.2008 · 2008 · External reference
A novel protein complex linking the δ2 glutamate receptor and autophagy: implications for neurodegeneration in lurcher mice
10.1016/s0896-6273(02)00861-9 · 2002 · External reference
Identification of a PDZ protein, PIST, as a binding partner for Rho effector Rhotekin: biochemical and cell-biological characterization of Rhotekin–PIST interaction
10.1042/bj20052015 · 2006 · External reference
AMPA receptor synaptic targeting regulated by Stargazin interactions with the golgi-resident PDZ protein nPIST
10.1523/jneurosci.1255-04.2004 · 2004 · External reference
The golgi-associated PDZ domain protein Gopc/PIST is required for synaptic targeting of mGluR5
10.1007/s12035-021-02504-9 · 2021 · External reference
PIST (GOPC) modulates the oncogenic voltage-gated potassium channel KV10.1
10.3389/fphys.2013.00201 · 2013 · External reference
The scaffolding protein GOPC regulates tight junction structure
10.1007/s00441-014-2088-1 · 2015 · External reference
The Golgi-associated PDZ domain protein PIST/GOPC stabilizes the β1-Adrenergic receptor in intracellular compartments after internalization
10.1074/jbc.m114.605725 · 2015 · External reference
Role of macrophage PIST protein in regulating Leishmania major infection
10.1021/acsinfecdis.4c00156 · 2024 · External reference
The ARFRP1-dependent Golgi scaffolding protein GOPC is required for insulin secretion from pancreatic β-cells
2020 · External reference
Role of actin cytoskeleton in the organization and function of ionotropic glutamate receptors
10.1016/j.crstbi.2021.10.001 · 2021 · External reference
Delphilin: a novel PDZ and formin homology domain-containing protein that synaptically colocalizes and interacts with glutamate receptor δ2 Subunit
10.1523/jneurosci.22-03-00803.2002 · 2002 · External reference
Emerging insights into the structure and function of ionotropic glutamate delta receptors
10.1111/bph.15313 · 2022 · External reference
Interaction of the C-terminal domain of δ glutamate receptor with spectrin in the dendritic spines of cultured Purkinje cells
10.1016/s0168-0102(99)00061-9 · 1999 · External reference
Direct interaction of GluRδ2 with Shank scaffold proteins in cerebellar Purkinje cells
10.1016/j.mcn.2004.02.007 · 2004 · External reference
Non diaphanous formin delphilin acts as a barbed end capping protein
10.1016/j.yexcr.2017.05.014 · 2017 · External reference
Kaptin functions as a barbed-end binding protein to control actin filament dynamics
10.1016/j.jmb.2025.169554 · 2026 · External reference
10.64898/2026.01.05.697755
10.64898/2026.01.05.697755 · External reference
Connectingthe puzzle pieces between cytoskeleton andsecretory pathway
10.1016/j.cub.2014.05.033 · 2014 · External reference
Nuclear protein FNBP4: a novel inhibitor of non-diaphanous formin FMN1-mediated actin cytoskeleton dynamics
10.1016/j.jbc.2025.108550 · 2025 · External reference
WH2 domain: a small, versatile adapter for actin monomers
10.1016/s0014-5793(01)03242-2 · 2002 · External reference
Highly accurate protein structure prediction with AlphaFold
10.1038/s41586-021-03819-2 · 2021 · External reference
Protein structure prediction on the Web: a case study using the Phyre server
10.1038/nprot.2009.2 · 2009 · External reference
The WH2 domain and actin nucleation – necessary but insufficient
10.1016/j.tibs.2016.03.004 · 2016 · External reference
Structure of a longitudinal actin dimer assembled by Tandem W domains – implications for actin filament nucleation
10.1016/j.jmb.2010.08.040 · 2010 · External reference
Rosetta FlexPepDock web server—high resolution modeling of peptide–protein interactions
10.1093/nar/gkr431 · 2011 · External reference
Structure of a filament-like actin trimer bound to the bacterial effector VopL
10.1016/j.cell.2013.09.019 · 2013 · External reference
Presence of actin binding motif in VgrG-1 toxin of Vibrio cholerae reveals the molecular mechanism of actin cross-linking
10.1016/j.ijbiomac.2019.04.026 · 2019 · External reference
Actin microfilaments are essential for the cytological positioning and morphology of the Golgi complex
10.1016/s0171-9335(98)80012-5 · 1998 · External reference
Biochemical and mechanical regulation of actin dynamics
10.1038/s41580-022-00508-4 · 2022 · External reference
Actin binding proteins: regulation of cytoskeletal microfilaments
10.1152/physrev.00026.2002 · 2003 · External reference
Actin acting at the Golgi
10.1007/s00418-013-1115-8 · 2013 · External reference
10.1016/b978-0-12-378630-2.00415-1
10.1016/b978-0-12-378630-2.00415-1 · External reference
WHAMM is an Arp2/3 complex activator that binds microtubules and functions in ER to Golgi transport
10.1016/j.cell.2008.05.032 · 2008 · External reference
Actin dynamics coupled to clathrin-coated vesicle formation at the trans-Golgi network
10.1083/jcb.200403120 · 2004 · External reference
Myosin 1b promotes the formation of post-Golgi carriers by regulating actin assembly and membrane remodelling at the trans-Golgi network
10.1038/ncb2262 · 2011 · External reference
Actin- and microtubule-dependent regulation of Golgi morphology by FHDC1
10.1091/mbc.e15-02-0070 · 2016 · External reference
STK16 regulates actin dynamics to control Golgi organization and cell cycle
2017 · External reference
JMY is involved in anterograde vesicle trafficking from the trans-Golgi network
10.1016/j.ejcb.2014.06.001 · 2014 · External reference
The Arp2/3 activator WASH controls the fission of endosomes through a large multiprotein complex
10.1016/j.devcel.2009.09.010 · 2009 · External reference
Expression of multiple formins in adult tissues and during developmental stages of mouse brain
10.1016/j.gep.2015.07.003 · 2015 · External reference
The Amber biomolecular simulation programs
10.1002/jcc.20290 · 2005 · External reference
KFC2: a knowledge-based hot spot prediction method based on interface solvation, atomic density, and plasticity features
10.1002/prot.23094 · 2011 · External reference
Unresolved reference
External reference
10.7554/elife.98363
10.7554/elife.98363 · External reference
The Amber biomolecular simulation programs
10.1002/jcc.20290 · ExternalCitation · doi-reference
KFC2: a knowledge-based hot spot prediction method based on interface solvation, atomic density, and plasticity features
10.1002/prot.23094 · ExternalCitation · doi-reference
Actin acting at the Golgi
10.1007/s00418-013-1115-8 · ExternalCitation · doi-reference
The scaffolding protein GOPC regulates tight junction structure
10.1007/s00441-014-2088-1 · ExternalCitation · doi-reference
The golgi-associated PDZ domain protein Gopc/PIST is required for synaptic targeting of mGluR5
10.1007/s12035-021-02504-9 · ExternalCitation · doi-reference
Glutamate-Receptor-Like molecule GluRδ2 involved in synapse Formation at parallel fiber-purkinje neuron synapses
10.1007/s12311-010-0170-0 · ExternalCitation · doi-reference
10.1016/b978-0-12-378630-2.00415-1
10.1016/b978-0-12-378630-2.00415-1 · ExternalCitation · doi-reference
WHAMM is an Arp2/3 complex activator that binds microtubules and functions in ER to Golgi transport
10.1016/j.cell.2008.05.032 · ExternalCitation · doi-reference
Structure of a filament-like actin trimer bound to the bacterial effector VopL
10.1016/j.cell.2013.09.019 · ExternalCitation · doi-reference
Role of actin cytoskeleton in the organization and function of ionotropic glutamate receptors
10.1016/j.crstbi.2021.10.001 · ExternalCitation · doi-reference
Connectingthe puzzle pieces between cytoskeleton andsecretory pathway
10.1016/j.cub.2014.05.033 · ExternalCitation · doi-reference
The Arp2/3 activator WASH controls the fission of endosomes through a large multiprotein complex
10.1016/j.devcel.2009.09.010 · ExternalCitation · doi-reference
JMY is involved in anterograde vesicle trafficking from the trans-Golgi network
10.1016/j.ejcb.2014.06.001 · ExternalCitation · doi-reference
Expression of multiple formins in adult tissues and during developmental stages of mouse brain
10.1016/j.gep.2015.07.003 · ExternalCitation · doi-reference
Presence of actin binding motif in VgrG-1 toxin of Vibrio cholerae reveals the molecular mechanism of actin cross-linking
10.1016/j.ijbiomac.2019.04.026 · ExternalCitation · doi-reference
Nuclear protein FNBP4: a novel inhibitor of non-diaphanous formin FMN1-mediated actin cytoskeleton dynamics
10.1016/j.jbc.2025.108550 · ExternalCitation · doi-reference
Structure of a longitudinal actin dimer assembled by Tandem W domains – implications for actin filament nucleation
10.1016/j.jmb.2010.08.040 · ExternalCitation · doi-reference
Kaptin functions as a barbed-end binding protein to control actin filament dynamics
10.1016/j.jmb.2025.169554 · ExternalCitation · doi-reference
Direct interaction of GluRδ2 with Shank scaffold proteins in cerebellar Purkinje cells
10.1016/j.mcn.2004.02.007 · ExternalCitation · doi-reference
The WH2 domain and actin nucleation – necessary but insufficient
10.1016/j.tibs.2016.03.004 · ExternalCitation · doi-reference
Non diaphanous formin delphilin acts as a barbed end capping protein
10.1016/j.yexcr.2017.05.014 · ExternalCitation · doi-reference
WH2 domain: a small, versatile adapter for actin monomers
10.1016/s0014-5793(01)03242-2 · ExternalCitation · doi-reference
Interaction of the C-terminal domain of δ glutamate receptor with spectrin in the dendritic spines of cultured Purkinje cells
10.1016/s0168-0102(99)00061-9 · ExternalCitation · doi-reference
Actin microfilaments are essential for the cytological positioning and morphology of the Golgi complex
10.1016/s0171-9335(98)80012-5 · ExternalCitation · doi-reference
A novel protein complex linking the δ2 glutamate receptor and autophagy: implications for neurodegeneration in lurcher mice
10.1016/s0896-6273(02)00861-9 · ExternalCitation · doi-reference
Role of macrophage PIST protein in regulating Leishmania major infection
10.1021/acsinfecdis.4c00156 · ExternalCitation · doi-reference
Myosin 1b promotes the formation of post-Golgi carriers by regulating actin assembly and membrane remodelling at the trans-Golgi network
10.1038/ncb2262 · ExternalCitation · doi-reference
Protein structure prediction on the Web: a case study using the Phyre server
10.1038/nprot.2009.2 · ExternalCitation · doi-reference
Biochemical and mechanical regulation of actin dynamics
10.1038/s41580-022-00508-4 · ExternalCitation · doi-reference
Highly accurate protein structure prediction with AlphaFold
10.1038/s41586-021-03819-2 · ExternalCitation · doi-reference
Identification of a PDZ protein, PIST, as a binding partner for Rho effector Rhotekin: biochemical and cell-biological characterization of Rhotekin–PIST interaction
10.1042/bj20052015 · ExternalCitation · doi-reference
The Golgi-associated PDZ domain protein PIST/GOPC stabilizes the β1-Adrenergic receptor in intracellular compartments after internalization
10.1074/jbc.m114.605725 · ExternalCitation · doi-reference
Actin dynamics coupled to clathrin-coated vesicle formation at the trans-Golgi network
10.1083/jcb.200403120 · ExternalCitation · doi-reference
Actin- and microtubule-dependent regulation of Golgi morphology by FHDC1
10.1091/mbc.e15-02-0070 · ExternalCitation · doi-reference
Rosetta FlexPepDock web server—high resolution modeling of peptide–protein interactions
10.1093/nar/gkr431 · ExternalCitation · doi-reference
Emerging insights into the structure and function of ionotropic glutamate delta receptors
10.1111/bph.15313 · ExternalCitation · doi-reference
Actin binding proteins: regulation of cytoskeletal microfilaments
10.1152/physrev.00026.2002 · ExternalCitation · doi-reference
AMPA receptor synaptic targeting regulated by Stargazin interactions with the golgi-resident PDZ protein nPIST
10.1523/jneurosci.1255-04.2004 · ExternalCitation · doi-reference
Delphilin: a novel PDZ and formin homology domain-containing protein that synaptically colocalizes and interacts with glutamate receptor δ2 Subunit
10.1523/jneurosci.22-03-00803.2002 · ExternalCitation · doi-reference
Differential regulation of synaptic plasticity and cerebellar motor learning by the C-Terminal PDZ-Binding motif of GluRδ2
10.1523/jneurosci.2553-07.2008 · ExternalCitation · doi-reference
PIST (GOPC) modulates the oncogenic voltage-gated potassium channel KV10.1
10.3389/fphys.2013.00201 · ExternalCitation · doi-reference
10.64898/2026.01.05.697755
10.64898/2026.01.05.697755 · ExternalCitation · doi-reference
10.7554/elife.98363
10.7554/elife.98363 · ExternalCitation · doi-reference