Research graph
References from Model of ribosomal translocation coupled with intra- and inter-subunit rotations. Local targets link to admitted publications; unresolved targets remain external evidence.
tRNA dynamics on the ribosome during translation
10.1073/pnas.0403884101 · 2004 · External reference
Spontaneous intersubunit rotation in single ribosomes
10.1016/j.molcel.2008.05.004 · 2008 · External reference
Coupling of ribosomal L1 stalk and tRNA dynamics during translation elongation
10.1016/j.molcel.2008.03.012 · 2008 · External reference
Intermediate states in the movement of transfer RNA in the ribosome
10.1038/342142a0 · 1989 · External reference
Locking and unlocking of ribosomal motions
10.1016/s0092-8674(03)00476-8 · 2003 · External reference
Peptidyl-tRNA regulates the GTPase activity of translation factors
10.1016/s0092-8674(03)00478-1 · 2003 · External reference
Hydrolysis of GTP by elongation factor G drives tRNA movement on the ribosome
10.1038/385037a0 · 1997 · External reference
Distinct functions of elongation factor G in ribosome recycling and translocation
10.1261/rna.1592509 · 2009 · External reference
mRNA translocation occurs during the second step of ribosomal intersubunit rotation
10.1038/nsmb.2011 · 2011 · External reference
Structures of modified eEF2 80S ribosome complexes reveal the role of GTP hydrolysis in translocation
10.1038/sj.emboj.7601677 · 2007 · External reference
Head swivel on the ribosome facilitates translocation by means of intra-subunit tRNA hybrid sites
10.1038/nature09547 · 2010 · External reference
10.1073/pnas.1320387110
10.1073/pnas.1320387110 · 2013 · External reference
Crystal structures of EF-G-ribosome complexes trapped in intermediate states of translocation
10.1126/science.1236086 · 2013 · External reference
Rotation of the head of the 30S ribosomal subunit during mRNA translocation
10.1073/pnas.1218999109 · 2012 · External reference
An explanation of biphasic characters of mRNA translocation in the ribosome
10.1016/j.biosystems.2014.01.009 · 2014 · External reference
Excited states of ribosome translocation revealed through integrative molecular modeling
10.1073/pnas.1108363108 · 2011 · External reference
Conformational changes of elongation factor G on the ribosome during tRNA translocation
10.1016/j.cell.2014.11.049 · 2015 · External reference
Single-molecule fluorescence measurements of ribosomal translocation dynamics
10.1016/j.molcel.2011.03.024 · 2011 · External reference
Coordinated conformational and compositional dynamics drive ribosome translocation
10.1038/nsmb.2567 · 2013 · External reference
Role of hybrid tRNA-binding states in ribosomal translocation
10.1073/pnas.0710146105 · 2008 · External reference
Conformational changes of the small ribosomal subunit during elongation factor G-dependent tRNA–mRNA translocation
10.1016/j.jmb.2004.08.097 · 2004 · External reference
Bases in 16S rRNA important for subunit association, tRNA binding, and translocation
10.1021/bi900472a · 2009 · External reference
Contribution of intersubunit bridges to the energy barrier of ribosomal translocation
10.1093/nar/gks1074 · 2013 · External reference
Control of ribosomal subunit rotation by elongation factor G
10.1126/science.1235970 · 2013 · External reference
Structures of the ribosome in intermediate states of ratcheting
10.1126/science.1175275 · 2009 · External reference
A steric block in translation caused by the antibiotic spectinomycin
10.1021/cb700100n · 2007 · External reference
Structural basis for hygromycin B inhibition of protein biosynthesis
10.1261/rna.1076908 · 2008 · External reference
Structures of the bacterial ribosome at 3.5Å resolution
10.1126/science.1117230 · 2005 · External reference
Structural analysis of kasugamycin inhibition of translation
10.1038/nsmb1150 · 2006 · External reference
The structure of the eukaryotic ribosome at 3.0Å resolution
10.1126/science.1212642 · 2011 · External reference
Structure of the 70S ribosome complexed with mRNA and tRNA
10.1126/science.1131127 · 2006 · External reference
Structures of the bacterial ribosome in classical and hybrid states of tRNA binding
10.1126/science.1202692 · 2011 · External reference
Structural aspects of messenger RNA reading frame maintenance by the ribosome
10.1038/nsmb.1790 · 2010 · External reference
The structures of the anti-tuberculosis antibiotics viomycin and capreomycin bound to the 70S ribosome
10.1038/nsmb.1755 · 2010 · External reference
Crystal structure of 70S ribosome with both cognate tRNAs in the E and P sites representing an authentic elongation complex
10.1371/journal.pone.0058829 · 2013 · External reference
The structure of the ribosome with elongation factor G trapped in the posttranslocational state
10.1126/science.1179709 · 2009 · External reference
Crystal structure of the ribosome at 5.5Å resolution
10.1126/science.1060089 · 2001 · External reference
Structural basis for translation termination on the 70S ribosome
10.1038/nature07115 · 2008 · External reference
Crystal structure of a translation termination complex formed with release factor RF2
10.1073/pnas.0810953105 · 2008 · External reference
Elongation factor G bound to the ribosome in an intermediate state of translocation
10.1126/science.1235490 · 2013 · External reference
Dynamics of forward and backward translocation of mRNA in the ribosome
10.1371/journal.pone.0070789 · 2013 · External reference
An elongation factor G-induced ribosome rearrangement precedes tRNA–mRNA translocation
10.1016/s1097-2765(03)00230-2 · 2003 · External reference
A ratchet-like inter-subunit reorganization of the ribosome during translocation
10.1038/35018597 · 2000 · External reference
Codondependent conformational change of elongation factor Tu preceding GTP hydrolysis on the ribosome
10.1002/j.1460-2075.1995.tb07259.x · 1995 · External reference
Effects of nucleotide- and aurodox-induced changes in elongation factor Tu conformation upon its interactions with aminoacyl tranfer RNA. A fluorescence study
10.1021/bi00459a014 · 1990 · External reference
An α to β conformational switch in EF-Tu
10.1016/s0969-2126(96)00123-2 · 1996 · External reference
Helix unwinding in the effector region of elongation factor EF-Tu–GDP
10.1016/s0969-2126(96)00122-0 · 1996 · External reference
Complete kinetic mechanism of elongation factor Tu-dependent binding of aminoacyl-tRNA to the A site of the E. coli ribosome
10.1093/emboj/17.24.7490 · 1998 · External reference
Induced fit in initial selection and proofreading of aminocyl-tRNA on the ribosome
10.1093/emboj/18.13.3800 · 1999 · External reference
Ribosome interactions of aminoacyl-tRNA and elongation factor Tu in the codon-recognition complex
2002 · External reference
Mechanisms of elongation on the ribosome: dynamics of a macromolecular machine
10.1042/bst0320733 · 2004 · External reference
Role and timing of GTP binding and hydrolysis during EF-G-dependent tRNA translocation on the ribosome
10.1073/pnas.0606099103 · 2006 · External reference
How ribosomes make peptide bonds
10.1016/j.tibs.2006.11.007 · 2007 · External reference
The ribosome uses two active mechanisms to unwind messenger RNA during translation
10.1038/nature10126 · 2011 · External reference
Molecular mechanics of 30S subunit head rotation
10.1073/pnas.1413731111 · 2014 · External reference
Crystal structure of release factor RF3 trapped in the GTP state on a rotated conformation of the ribosome
10.1261/rna.031187.111 · 2012 · External reference
Deducing the kinetics of protein synthesis in vivo from the transition rates measured in vitro
10.1371/journal.pcbi.1003909 · 2014 · External reference
Identification of two distinct hybrid state intermediates on the ribosome
10.1016/j.molcel.2007.01.022 · 2007 · External reference
Biphasic character of ribosomal translocation and non-Michaelis–Menten kinetics of translation
10.1103/physreve.90.062703 · 2014 · External reference
Elongation factor G stabilizes the hybrid-state conformation of the 70S ribosome
10.1261/rna.601507 · 2007 · External reference
Real-time tRNA transit on single translating ribosomes at codon resolution
10.1038/nature08925 · 2010 · External reference
Dynamics of tRNA occupancy and dissociation during translation by the ribosome
10.1016/j.jtbi.2012.09.023 · 2013 · External reference
