Research graph
References from Oxidative stress-mediated antitumor activity of erythorbic acid in high doses. Local targets link to admitted publications; unresolved targets remain external evidence.
Regulation of collagen synthesis by ascorbic acid. Ascorbic acid increases type I procollagen mRNA
10.1016/0006-291x(82)91157-3 · 1982 · External reference
Ascorbic acid and hepatic drug metabolism
10.1016/s0022-3565(25)30596-3 · 1976 · External reference
Effect of ascorbic acid on iron absorption from different types of meals. Studies with ascorbic-acid-rich foods and synthetic ascorbic acid given in different amounts with different meals
1986 · External reference
Biology of free radical scavengers: an evaluation of ascorbate
10.1096/fasebj.7.12.8375611 · 1993 · External reference
Resveratrol-Cu(II) induced DNA breakage in human peripheral lymphocytes: implications for anticancer properties
10.1016/j.febslet.2005.04.077 · 2005 · External reference
Electrochemical behavior and antioxidant and prooxidant activity of natural phenolics
10.3390/12102327 · 2007 · External reference
Prooxidant activity of curcumin: copper-dependent formation of 8-hydroxy-2′-deoxyguanosine in DNA and induction of apoptotic cell death
10.1016/j.tiv.2004.03.009 · 2004 · External reference
Ascorbic acid: chemistry, biology and the treatment of cancer
1826 · External reference
Supplemental ascorbate in the supportive treatment of cancer: reevaluation of prolongation of survival times in terminal human cancer
10.1073/pnas.75.9.4538 · 1978 · External reference
Phase I clinical trial of i.v. ascorbic acid in advanced malignancy
10.1093/annonc/mdn377 · 2008 · External reference
Parenteral ascorbate as a cancer therapeutic: a reassessment based on pharmacokinetics
10.1089/ars.2013.5372 · 2013 · External reference
Vitamin C pharmacokinetics: implications for oral and intravenous use
10.7326/0003-4819-140-7-200404060-00010 · 2004 · External reference
Pharmacologic ascorbic acid concentrations selectively kill cancer cells: action as a pro-drug to deliver hydrogen peroxide to tissues
10.1073/pnas.0506390102 · 2005 · External reference
Ascorbate in pharmacologic concentrations selectively generates ascorbate radical and hydrogen peroxide in extracellular fluid in vivo
10.1073/pnas.0702854104 · 2007 · External reference
Pharmacologic doses of ascorbate act as a prooxidant and decrease growth of aggressive tumor xenografts in mice
10.1073/pnas.0804226105 · 2008 · External reference
Mitochondrial O2.- and H2O2 mediate glucose deprivation-induced stress in human cancer cells
10.1074/jbc.m411662200 · 2005 · External reference
Mechanisms of oxidant-mediated cell injury. The glycolytic and mitochondrial pathways of ADP phosphorylation are major intracellular targets inactivated by hydrogen peroxide
10.1016/s0021-9258(19)77928-9 · 1988 · External reference
Dual regulation of caspase activity by hydrogen peroxide: implications for apoptosis
10.1016/s0014-5793(97)01068-5 · 1997 · External reference
Vitamin C activity of erythorbic acid in ascorbic acid-deficient guinea pigs
10.3177/jnsv.41.17 · 1995 · External reference
Effectiveness of isoascorbate versus ascorbate as an inducer of collagen synthesis in primary avian tendon cells
10.1093/jn/120.2.185 · 1990 · External reference
Erythorbic acid is a potent enhancer of nonheme-iron absorption
10.1093/ajcn/79.1.99 · 2004 · External reference
Inhibiting effect of ascorbic acid on the growth of human mammary tumor xenografts
10.1093/ajcn/54.6.1274s · 1991 · External reference
Determination of ascorbic acid and its related compounds in foods and beverages by hydrophilic interaction liquid chromatography
10.1016/j.jchromb.2007.03.024 · 2007 · External reference
Pharmacologic concentrations of ascorbate are achieved by parenteral administration and exhibit antitumoral effects
10.1016/j.freeradbiomed.2009.02.016 · 2009 · External reference
Intravenously administered vitamin C as cancer therapy: three cases
10.1503/cmaj.050346 · 2006 · External reference
Intravenous vitamin C as a chemotherapy agent: a report on clinical cases
2004 · External reference
6-Deoxy-6-[131I]iodo-l-ascorbic acid for the in vivo study of ascorbate: autoradiography, biodistribution in normal and hypolipidemic rats, and in tumor-bearing nude mice
10.1248/bpb.32.1906 · 2009 · External reference
Stromal cell oxidation: a mechanism by which tumors obtain vitamin C
1999 · External reference
Ascorbic acid intake and plasma levels in healthy elderly people
10.1093/ajcn/46.2.290 · 1987 · External reference
Ascorbic acid and dehydroascorbic acid measurements in human plasma and serum
10.1093/ajcn/54.4.712 · 1991 · External reference
Persistent oxidative stress in colorectal carcinoma patients
10.1002/ijc.10610 · 2002 · External reference
