Research graph
References from Enzymatic attributes of an l-isoaspartyl methyltransferase from Candida utilis and its role in cell survival. Local targets link to admitted publications; unresolved targets remain external evidence.
Unresolved reference
1999 · External reference
Isoaspartate in peptides and proteins: formation, significance, and analysis
10.1016/s0731-7085(99)00230-7 · 2000 · External reference
Deamidation destabilizes and triggers aggregation of a lens protein, βA3-crystallin
10.1110/ps.035410.108 · 2008 · External reference
Structural elements affecting the recognition of l-isoaspartyl residues by the l-isoaspartyl/d-aspartyl protein methyltransferase. Implications for the repair hypothesis
10.1016/s0021-9258(18)55010-9 · 1991 · External reference
The role of protein l-Isoaspartyl/d-aspartyl O-methyltransferase (PIMT) in intracellular signal transduction
10.1002/cbdv.200900273 · 2010 · External reference
Protein repair in the brain, proteomic analysis of endogenous substrates for Protein l-Isoaspartyl Methyltransferase in mouse brain
10.1074/jbc.m606958200 · 2006 · External reference
Regulation of enzymatic activity by deamidation and their subsequent repair by Protein l-isoaspartyl Methyl transferase
10.1007/s12010-012-9942-y · 2012 · External reference
Molecular phylogenetics of a protein repair methyltransferase
10.1016/s0305-0491(96)00333-1 · 1997 · External reference
Distribution of an l-isoaspartyl protein methyltransferase in eubacteria
10.1128/jb.174.2.355-361.1992 · 1992 · External reference
Distinct patterns of expression but similar biochemical properties of protein l-Isoaspartyl Methyltransferase in higher plants
10.1104/pp.125.2.1023 · 2001 · External reference
Protein l-isoaspartyl methyltransferase from the nematode Caenorhabditis elegans: genomic structure and substrate specificity
10.1021/bi00034a012 · 1995 · External reference
Structural organization and developmental expression of the protein l-isoaspartyl methyltransferase gene from Drosophila melanogaster
10.1016/s0965-1748(96)00071-9 · 1997 · External reference
Purification of homologous protein carboxyl methyltransferase isozymes from human and bovine erythrocytes
10.1021/bi00414a042 · 1988 · External reference
Transgenic expression of the protein-l-isoaspartyl methyltransferase (PIMT) gene in the brain rescues mice from the fatal epilepsy of PIMT deficiency
10.1002/jnr.10301 · 2002 · External reference
Overexpression of l-isoaspartate O-methyltransferase in Escherichia coli increases heat shock survival by a mechanism independent of methyltransferase activity
10.1074/jbc.m308423200 · 2003 · External reference
The interplay between protein l-isoaspartyl methyltransferase activity and insulin-like signaling to extend lifespan in Caenorhabditis elegans
10.1371/journal.pone.0020850 · 2011 · External reference
Life with 6000 genes
10.1126/science.274.5287.546 · 1996 · External reference
Non-repair pathways for minimizing protein isoaspartyl damage in the yeast Saccharomyces cerevisiae
10.1074/jbc.m114.564385 · 2014 · External reference
ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe
10.1038/nbt1222 · 2006 · External reference
Correlation between stationary phase survival and acid trehalase activity in yeast
10.1016/s0167-4889(97)00156-0 · 1998 · External reference
Additional modules for versatile and economical PCR-based gene deletion and modification in Saccharomyces cerevisiae
10.1002/(sici)1097-0061(199807)14:10<953::aid-yea293>3.0.co;2-u · 1998 · External reference
Transformation of yeast by lithium acetate/single-stranded carrier DNA/polyethylene glycol method
10.1016/s0076-6879(02)50957-5 · 2002 · External reference
Protein measurement with the Folin phenol reagent
10.1016/s0021-9258(19)52451-6 · 1951 · External reference
Unresolved reference
1974 · External reference
Rabbit red blood cell hexokinase. Purification and properties
10.1016/s0021-9258(19)86096-9 · 1980 · External reference
Purification and characterization of glutamate dehydrogenase as another isoprotein binding to the membrane of rough endoplasmic reticulum
10.1002/(sici)1097-4644(20000201)76:2<244::aid-jcb8>3.0.co;2-k · 1999 · External reference
Cleavage of structural proteins during the assembly of the head of bacteriophage T4
10.1038/227680a0 · 1970 · External reference
Evaluation of secondary structure of proteins from UV circular dichroism spectra using an unsupervised learning neural network
10.1093/protein/6.4.383 · 1993 · External reference
Unresolved reference
External reference
The graphical determination of Km and Ki
10.1042/bj1290197 · 1972 · External reference
Preparation of proteins and peptides for mass spectrometry analysis in a bottom-up proteomics workflow
2009 · External reference
A new bioinformatics analysis tools framework at EMBL-EBI
10.1093/nar/gkq313 · 2010 · External reference
Basic local alignment search tool
10.1016/s0022-2836(05)80360-2 · 1990 · External reference
The genome portal of the department of energy joint genome institute: 2014 updates
10.1093/nar/gkt1069 · 2014 · External reference
Unresolved reference
External reference
Unresolved reference
External reference
Protein secondary structure prediction based on position-specific scoring matrices
10.1006/jmbi.1999.3091 · 1999 · External reference
CDD: a conserved domain database for the functional annotation of proteins
10.1093/nar/gkq1189 · 2011 · External reference
Fast, scalable generation of high-quality protein multiple sequence alignments using Clustal Omega
10.1038/msb.2011.75 · 2011 · External reference
EvolView, an online tool for visualizing, annotating and managing phylogenetic trees
10.1093/nar/gks576 · 2012 · External reference
Comparative proteome analysis of Saccharomyces cerevisiae grown in chemostat cultures limited for glucose or ethanol
10.1074/mcp.m400087-mcp200 · 2005 · External reference
Considerations in the Identification of Endogenous Substrates for Protein l-Isoaspartyl Methyltransferase: The Case of Synuclein
10.1371/journal.pone.0043288 · 2012 · External reference
Phylogenetic analysis of five medically important Candida species as deduced on the basis of small ribosomal subunit RNA sequences 7
1991 · External reference
The nucleotide sequences of the 5 S rRNAs of seven molds and a yeast and their use in studying ascomycete phylogeny
1984 · External reference
From Saccharomyces cerevisiae to Candida glabrata in a few easy steps: important adaptations for an opportunistic pathogen
10.1111/j.1574-6968.2010.02102.x · 2011 · External reference
Purification and characterization of a trehalase–invertase enzyme with dual activity from Candida utilis
10.1016/j.abb.2012.03.026 · 2012 · External reference
Arginine mediated purification of trehalose-6-phosphate synthase (TPS) from Candida utilis: Its characterization and regulation
10.1016/j.bbagen.2011.06.025 · 2011 · External reference
Metabolic responses of Saccharomyces cerevisiae CBS 8066 and Candida utilis CBS 621 upon transition from glucose limitation to glucose excess
10.1002/yea.320040406 · 1988 · External reference
Competition for glucose between the yeasts Saccharomyces cerevisiae and Candida utilis
10.1128/aem.55.12.3214-3220.1989 · 1989 · External reference
Limited accumulation of damaged proteins in l-isoaspartyl (d-aspartyl) O-methyltransferase-deficient mice
10.1074/jbc.m100987200 · 2001 · External reference
Do damaged proteins accumulate in Caenorhabditis elegans l-isoaspartate methyltransferase (pcm-1) deletion mutants?
10.1006/abbi.1999.1114 · 1999 · External reference
Integrated proteomic analysis of major isoaspartyl-containing proteinsin the urine of wild type and protein l-isoaspartate O-methyltransferase-deficient mice
10.1021/ac303428h · 2013 · External reference
Impact of antibody aggregation on a flow through anion-exchange membrane process
10.1002/btpr.483 · 2010 · External reference
Expression, purification, and characterization of the protein repair l-Isoaspartyl Methyltransferase from Arabidopsis thaliana
10.1006/prep.2000.1311 · 2000 · External reference
Cloning, Expression and Purification of Rat Brain Protein l-isoaspartyl Methyltransferase
10.1006/prep.1995.1041 · 1995 · External reference
A highly active protein repair enzyme from an extreme thermophile: the L-isoaspartyl methyltransferase from Thermotoga maritima
10.1006/abbi.1998.0830 · 1998 · External reference
Protein repair methyltransferase from the hyperthermophilic archaeon Pyrococcus furiosus: unusual methyl-accepting affinity for d-aspartyl and N-succinyl-containing peptides
10.1074/jbc.m108261200 · 2002 · External reference
Fungal-bacterial interactions and their relevance to oral health: linking the clinic and the bench
10.3389/fcimb.2014.00101 · 2014 · External reference
Thermally induced changes in the structure and activity of yeast hexokinase B
10.1016/j.bpc.2008.07.004 · 2008 · External reference
Spontaneous chemical reversion of an active site mutation: deamidation of an asparagine residue replacing thecatalytic aspartic acid of glutamate dehydrogenase
10.1021/bi047679u · 2005 · External reference
Effect of protein structure on deamidation rate in the Fc fragment of an IgG1 monoclonal antibody
10.1002/pro.173 · 2009 · External reference
Prediction of protein deamidation rates from primary and three-dimensional structure
10.1073/pnas.071066498 · 2001 · External reference
Structural integrity of histone H2B in vivo requires the activity of protein l-isoaspartyl methyltransferase, a putative protein repair enzyme
10.1074/jbc.m106682200 · 2001 · External reference
Effects of adenosine dialdehyde on S-adenosylhomocysteine hydrolase and S-adenosylmethionine-dependent transmethylations in mouse L929 cells
10.1016/s0026-895x(25)15050-5 · 1984 · External reference
Up-regulation of protein l-isoaspartyl methyltransferase expression by lithium is mediated by glycogen synthase kinase-3 inactivation and beta-catenin stabilization
10.1016/j.neuropharm.2008.05.033 · 2008 · External reference
Reactive oxygen species generated by thiol-modifying phenylarsine oxide stimulate the expression of protein l-isoaspartyl methyltransferase
10.1016/j.bbrc.2008.04.009 · 2008 · External reference
The protein l-isoaspartyl (d-aspartyl) methyltransferase protects against dopamine-induced apoptosis in neuroblastoma SH-SY5Y cells
10.1016/j.neuroscience.2015.03.026 · 2015 · External reference
Proteomic identification of novel substrates of a protein isoaspartyl methyltransferase repair enzyme
10.1074/jbc.m605421200 · 2006 · External reference
Yeast as a model system for anticancer drug discovery
10.1038/nrc1372 · 2004 · External reference
Yeast models of human mitochondrial diseases
10.1002/tbmb.718540876 · 2003 · External reference
Integrating genetic approaches into the discovery of anticancer drugs
10.1126/science.278.5340.1064 · 1997 · External reference
