References

The value of fecal tumor M2 pyruvate kinase as a diagnostic tool for colorectal cancer screening

2012 · External reference

The function of the respiratory supercomplexes: The plasticity model

10.1016/j.bbabio.2013.12.009 · 2014 · External reference

Genes of glycolysis are ubiquitously overexpressed in 24 cancer classes

10.1016/j.ygeno.2004.08.010 · 2004 · External reference

Mitochondria: are mitochondria accessory to metastasis?

10.1016/j.biocel.2014.03.009 · 2014 · External reference

Different kinetics of the regulation of respiration in permeabilized cardiomyocytes and in HL-1 cardiac cells. Importance of cell structure/organization for respiration regulation

10.1016/j.bbabio.2006.09.008 · 2006 · External reference

Possible role of cytoskeleton in intracellular arrangement and regulation of mitochondria

10.1113/eph8802511 · 2003 · External reference

Functional significance of mitochondrial bound hexokinase in tumor cell metabolism. Evidence for preferential phosphorylation of glucose by intramitochondrially generated ATP

10.1016/s0021-9258(19)77853-3 · 1988 · External reference

Role of angiogenesis inhibitors in colorectal cancer: sensitive and insensitive tumors

10.2174/156800912800190929 · 2012 · External reference

Enzymes of creatine biosynthesis, arginine and methionine metabolism in normal and malignant cells

10.1111/j.1742-4658.2008.06718.x · 2008 · External reference

Mitochondrial mutations in cancer

10.1038/sj.onc.1209607 · 2006 · External reference

Vascular endothelial growth factor-B in physiology and disease

10.1152/physrev.00028.2013 · 2014 · External reference

Mitochondrial hexokinase of rat hepatoma cells in culture: solubilization and kinetic properties

10.1021/bi00563a006 · 1980 · External reference

Dependency of Colorectal Cancer on a TGF-β-Driven Program in Stromal Cells for Metastasis Initiation

10.1016/j.ccr.2012.08.013 · 2012 · External reference

Expression of HIF-1alpha and VEGF in colorectal cancer: association with clinical outcomes and prognostic implications

10.1186/1471-2407-9-432 · 2009 · External reference

Evaluation of metastatic and angiogenic potentials of human colon carcinoma cells in chick embryo model systems

10.1007/s10585-009-9293-4 · 2009 · External reference

Aspirin use and survival after diagnosis of colorectal cancer

10.1001/jama.2009.1112 · 2009 · External reference

Genetic insights into OXPHOS defect and its role in cancer

10.1016/j.bbabio.2010.10.023 · 2011 · External reference

Mitochondrial DNA mutations in human cancer

10.1038/sj.onc.1209604 · 2006 · External reference

Role of mitochondria-associated hexokinase II in cancer cell death induced by 3-bromopyruvate

10.1016/j.bbabio.2009.03.003 · 2009 · External reference

ANT2 isoform required for cancer cell glycolysis

10.1007/s10863-005-8642-5 · 2005 · External reference

Adenine nucleotide translocase 2 is a key mitochondrial protein in cancer metabolism

10.1016/j.bbabio.2010.10.008 · 2011 · External reference

Mechanisms related to [18F]fluorodeoxyglucose uptake of human colon cancers transplanted in nude mice

1999 · External reference

Understanding the mechanisms of action of antiangiogenic agents in metastatic colorectal cancer: a clinician's perspective

10.1016/j.ctrv.2014.07.001 · 2014 · External reference

Functional polarization of tumour-associated macrophages by tumour-derived lactic acid

10.1038/nature13490 · 2014 · External reference

Cancer metabolism, stemness and tumor recurrence: MCT1 and MCT4 are functional biomarkers of metabolic symbiosis in head and neck cancer

10.4161/cc.24092 · 2013 · External reference

Metabolic reprogramming in cancer: Unraveling the role of glutamine in tumorigenesis

10.1016/j.semcdb.2012.02.002 · 2012 · External reference

HIF-1alpha/GPER signaling mediates the expression of VEGF induced by hypoxia in breast cancer associated fibroblasts (CAFs)

10.1186/bcr3458 · 2013 · External reference

Defining the molecular basis of tumor metabolism: a continuing challenge since Warburg's discovery

10.1159/000335792 · 2011 · External reference

Beyond aerobic glycolysis: Transformed cells can engage in glutamine metabolism that exceeds the requirement for protein and nucleotide synthesis

10.1073/pnas.0709747104 · 2007 · External reference

Pyruvate fuels mitochondrial respiration and proliferation of breast cancer cells: effect of monocarboxylate transporter inhibition

10.1042/bj20120294 · 2012 · External reference

Adenylate kinase and AMP signaling networks: Metabolic monitoring, signal communication and body energy sensing

10.3390/ijms10041729 · 2009 · External reference

Phosphotransfer networks and cellular energetics

10.1242/jeb.00426 · 2003 · External reference

Adenylate kinase-catalyzed phosphotransfer in the myocardium: increased contribution in heart failure

10.1161/01.res.84.10.1137 · 1999 · External reference

Tumor angiogenesis: therapeutic implications

10.1056/nejm197111182852108 · 1971 · External reference

The mitochondrial ATPase inhibitory factor 1 triggers a ROS-mediated retrograde prosurvival and proliferative response

10.1016/j.molcel.2012.01.008 · 2012 · External reference

Tumor glycolysis as a target for cancer therapy: progress and prospects

10.1186/1476-4598-12-152 · 2013 · External reference

Oxygen solubility in experimental media

2001 · External reference

The CpG island methylator phenotype and chromosomal instability are inversely correlated in sporadic colorectal cancer

10.1053/j.gastro.2006.09.018 · 2007 · External reference

Mitochondria as targets for cancer chemotherapy

10.1016/j.semcancer.2008.11.007 · 2009 · External reference

Studies of the role of tubulin beta II isotype in regulation of mitochondrial respiration in intracellular energetic units in cardiac cells

10.1016/j.yjmcc.2011.07.027 · 2012 · External reference

Uridine kinase, adenylate kinase, and guanase in human lung tumors

1980 · External reference

MicroRNA-143 down-regulates Hexokinase 2 in colon cancer cells

10.1186/1471-2407-12-232 · 2012 · External reference

Oxidative phosphorylation and its coupling to mitochondrial creatine and adenylate kinases in human gastric mucosa

10.1152/ajpregu.00162.2006 · 2006 · External reference

Isoenzyme pattern and subcellular localization of hexokinases in human breast cancer and nonpathological breast tissue

10.1002/ijc.2910340111 · 1984 · External reference

Regulation of respiration in muscle cells in vivo by VDAC through interaction with the cytoskeleton and MtCK within Mitochondrial Interactosome

10.1016/j.bbamem.2011.12.034 · 2012 · External reference

Modular organization of cardiac energy metabolism: energy conversion, transfer and feedback regulation

10.1111/apha.12287 · 2015 · External reference

Mitochondria-cytoskeleton interaction: distribution of beta-tubulins in cardiomyocytes and HL-1 cells

10.1016/j.bbabio.2011.01.010 · 2011 · External reference

GLUT1 glucose transporter expression in colorectal carcinoma: a marker for poor prognosis

10.1002/(sici)1097-0142(19980701)83:1<34::aid-cncr5>3.0.co;2-e · 1998 · External reference

Hallmarks of cancer: the next generation

10.1016/j.cell.2011.02.013 · 2011 · External reference

Hypoxia--a key regulatory factor in tumour growth

10.1038/nrc704 · 2002 · External reference

Sphingolipids and lifespan regulation

2014 · External reference

Molecular mechanism underlying the detection of colorectal cancer by 18F-2-fluoro-2-deoxy-d-glucose positron emission tomography

10.1007/s11605-011-1727-z · 2012 · External reference

Post-translational regulation of the microtubule cytoskeleton: mechanisms and functions

10.1038/nrm3227 · 2011 · External reference

1H HR-MAS NMR spectroscopy of tumor-induced local metabolic “field-effects” enables colorectal cancer staging and prognostication

10.1021/pr3010106 · 2013 · External reference

Creatine kinase activity and isoenzymes in lung, colon and liver carcinomas

10.1038/bjc.1997.432 · 1997 · External reference

Metabolic control analysis of cellular respiration in situ in intraoperational samples of human breast cancer

10.1007/s10863-012-9457-9 · 2012 · External reference

Metabolic control analysis of respiration in human cancer tissue

10.3389/fphys.2013.00151 · 2013 · External reference

An in situ study of bioenergetic properties of human colorectal cancer: the regulation of mitochondrial respiration and distribution of flux control among the components of ATP synthasome

10.1016/j.biocel.2014.09.004 · 2014 · External reference

31P Magnetic Resonance Spectroscopy of Human Colon Cancer

1990 · External reference

Comparative analysis of some aspects of mitochondrial metabolism in differentiated and undifferentiated neuroblastoma cells

10.1007/s10863-013-9529-5 · 2014 · External reference

Glucose catabolism in the rabbit VX2 tumor model for liver cancer: characterization and targeting hexokinase

10.1016/s0304-3835(01)00667-x · 2001 · External reference

Lactate dehydrogenase 5 (LDH5) relates to up-regulated hypoxia inducible factor pathway and metastasis in colorectal cancer

10.1007/s10585-005-2343-7 · 2005 · External reference

Cytoskeleton and regulation of mitochondrial function: the role of beta-tubulin II

10.3389/fphys.2013.00082 · 2013 · External reference

Striking differences between the kinetics of regulation of respiration by ADP in slow-twitch and fast-twitch muscles in vivo

10.1111/j.1432-1033.1996.00909.x · 1996 · External reference

Analysis of mitochondrial function in situ in permeabilized muscle fibers, tissues and cells

10.1038/nprot.2008.61 · 2008 · External reference

Tumoral and tissue-specific expression of the major human β-tubulin isotypes

10.1002/cm.20436 · 2010 · External reference

Macrophages regulate the angiogenic switch in a mouse model of breast cancer

10.1158/0008-5472.can-06-1278 · 2006 · External reference

Oncogenes induce the cancer-associated fibroblast phenotype: Metabolic symbiosis and “fibroblast addiction” are new therapeutic targets for drug discovery

10.4161/cc.25695 · 2013 · External reference

Enzymatically inactive adenylate kinase 4 interacts with mitochondrial ADP/ATP translocase

10.1016/j.biocel.2008.12.002 · 2009 · External reference

Inhibitive effect of 3-bromopyruvic acid on human breast cancer MCF-7 cells involves cell cycle arrest and apoptotic induction

2009 · External reference

Analysis of relative gene expression data using real-time quantitative PCR and the 2−ΔΔCT Method

10.1006/meth.2001.1262 · 2001 · External reference

Voltage-dependent anion channels modulate mitochondrial metabolism in cancer cells: regulation by free tubulin and erastin

10.1074/jbc.m112.433847 · 2013 · External reference

Cancer cells metabolically “fertilize” the tumor microenvironment with hydrogen peroxide, driving the Warburg effect: implications for PET imaging of human tumors

10.4161/cc.10.15.16585 · 2011 · External reference

Hexokinase II: cancer’s double-edged sword acting as both facilitator and gatekeeper of malignancy when bound to mitochondria

10.1038/sj.onc.1209603 · 2006 · External reference

Hexokinase-2 bound to mitochondria: cancer’s stygian link to the “Warburg Effect” and a pivotal target for effective therapy

10.1016/j.semcancer.2008.11.006 · 2009 · External reference

Mitochondrial function and energy metabolism in cancer cells: Past overview and future perspectives

10.1016/j.mito.2009.01.009 · 2009 · External reference

Succinate dehydrogenase deficient gastrointestinal stromal tumors (GISTs) – a review

10.1016/j.biocel.2014.05.033 · 2014 · External reference

Comparative analysis of the bioenergetics of adult cardiomyocytes and nonbeating HL-1 cells: respiratory chain activities, glycolytic enzyme profiles, and metabolic fluxes

10.1139/y09-018 · 2009 · External reference

Mitochondrial interactosome in health and disease: structural and functional aspects of molecular system bioenergetics of muscle and neuronal cells

2010 · External reference

Creatine kinase brain overexpression protects colorectal cells from various metabolic and non-metabolic stresses

10.1002/jcb.23020 · 2011 · External reference

Who controls the ATP supply in cancer cells? Biochemistry lessons to understand cancer energy metabolism

10.1016/j.biocel.2014.01.025 · 2014 · External reference

Energy metabolism in tumor cells

10.1111/j.1742-4658.2007.05686.x · 2007 · External reference

The bioenergetics of cancer: Is glycolysis the main ATP supplier in all tumor cells?

10.1002/biof.31 · 2009 · External reference

Class III beta-tubulin overexpression is a prominent mechanism of paclitaxel resistance in ovarian cancer patients

10.1158/1078-0432.298.11.1 · 2005 · External reference

Adipocytes promote ovarian cancer metastasis and provide energy for rapid tumor growth

10.1038/nm.2492 · 2011 · External reference

HIF-1 mediates adaptation to hypoxia by actively downregulating mitochondrial oxygen consumption

10.1016/j.cmet.2006.01.012 · 2006 · External reference

Regulation of hexokinase binding to VDAC

10.1007/s10863-008-9148-8 · 2008 · External reference

Progressive decrease of phosphocreatine, creatine and creatine kinase in skeletal muscle upon transformation to sarcoma

10.1111/j.1742-4658.2008.06475.x · 2008 · External reference

3-bromopyruvate (3BP) a fast acting, promising, powerful, specific, and effective “small molecule” anti-cancer agent taken from labside to bedside: introduction to a special issue

10.1007/s10863-012-9425-4 · 2012 · External reference

Glycolysis inhibition for anticancer treatment

10.1038/sj.onc.1209597 · 2006 · External reference

Cooperation and competition in the evolution of ATP-producing pathways

10.1126/science.1058079 · 2001 · External reference

Deficiency of the complex I of the mitochondrial respiratory chain but improved adenylate control over succinate-dependent respiration are human gastric cancer-specific phenomena

10.1007/s11010-012-1399-3 · 2012 · External reference

Mutant ras oncogenes upregulate VEGF/VPF expression: implications for induction and inhibition of tumor angiogenesis

1995 · External reference

Thrombin is a novel regulator of hexokinase activity in mesangial cells

10.1046/j.1523-1755.2000.00091.x · 2000 · External reference

Oxidative phosphorylation is impaired by prolonged hypoxia in breast and possibly in cervix carcinoma

10.1016/j.biocel.2010.07.010 · 2010 · External reference

Oxidative phosphorylation as a target to arrest malignant neoplasias

10.2174/092986711796391561 · 2011 · External reference

Substrate oxidation and ATP supply in AS-30D hepatoma cells

10.1006/abbi.1999.1582 · 2000 · External reference

On the role of VDAC in apoptosis: fact and fiction

10.1007/s10863-005-6566-8 · 2005 · External reference

Structure-function relationships in feedback regulation of energy fluxes in vivo in health and disease: mitochondrial interactosome

10.1016/j.bbabio.2010.01.011 · 2010 · External reference

Heterogeneity of ADP diffusion and regulation of respiration in cardiac cells

10.1016/s0006-3495(03)70065-4 · 2003 · External reference

Permeabilized cell and skinned fiber techniques in studies of mitochondrial function in vivo

10.1023/a:1006834912257 · 1998 · External reference

Up-regulation of the ATPase inhibitory factor 1 (IF1) of the mitochondrial H+-ATP synthase in human tumors mediates the metabolic shift of cancer cells to a Warburg phenotype

10.1074/jbc.m110.146480 · 2010 · External reference

Regulation of cancer cell metabolism by hypoxia-inducible factor 1

10.1016/j.semcancer.2008.11.009 · 2009 · External reference

Intracellular energetic units in healthy and diseased hearts

2005 · External reference

Characterization of porin isoforms expressed in tumor cells

10.1046/j.1432-1327.2000.01687.x · 2000 · External reference

The reverse warburg effect in osteosarcoma

10.18632/oncotarget.2352 · 2014 · External reference

Understanding the Warburg effect and the prognostic value of stromal caveolin-1 as a marker of a lethal tumor microenvironment

10.1186/bcr2892 · 2011 · External reference

Mitochondrial metabolism in cancer metastasis: visualizing tumor cell mitochondria and the “reverse Warburg effect” in positive lymph node tissue

10.4161/cc.19841 · 2012 · External reference

HIF-1 inhibits mitochondrial biogenesis and cellular respiration in VHL-deficient renal cell carcinoma by repression of C-MYC activity

10.1016/j.ccr.2007.04.001 · 2007 · External reference

Intracellular ATP Levels Are a Pivotal Determinant of Chemoresistance in Colon Cancer Cells

10.1158/0008-5472.can-11-1674 · 2012 · External reference

Cancer metabolism: facts, fantasy, and fiction

10.1016/j.bbrc.2003.11.136 · 2004 · External reference

The role of tubulin in the mitochondrial metabolism and arrangement in muscle cells

10.1007/s10863-014-9579-3 · 2014 · External reference

High efficiency of energy flux controls within mitochondrial interactosome in cardiac intracellular energetic units

10.1016/j.bbabio.2011.08.005 · 2011 · External reference

Direct measurement of energy fluxes from mitochondria into cytoplasm in permeabilized cardiac cells in situ: some evidence for mitochondrial interactosome

10.1007/s10863-009-9224-8 · 2009 · External reference

The Warburg effect: insights from the past decade

10.1016/j.pharmthera.2012.11.003 · 2013 · External reference

Understanding the warburg effect: the metabolic requirements of cell proliferation

10.1126/science.1160809 · 2009 · External reference

The metabolism of tumors in the body

10.1085/jgp.8.6.519 · 1927 · External reference

Role of mitochondria-cytoskeleton interactions in respiration regulation and mitochondrial organization in striated muscles

10.1016/j.bbabio.2013.10.011 · 2014 · External reference

Coomassie staining as loading control in western blot analysis

10.1021/pr1011476 · 2011 · External reference

Evidence for a stromal-epithelial “lactate shuttle” in human tumors: MCT4 is a marker of oxidative stress in cancer-associated fibroblasts.

10.4161/cc.10.11.15659 · 2011 · External reference

Oncogene ablation-resistant pancreatic cancer cells depend on mitochondrial function

10.1038/nature13611 · 2014 · External reference

Selective inhibition of beta-F1-ATPase mRNA translation in human tumours

10.1042/bj20091570 · 2010 · External reference

Using the “reverse Warburg effect” to identify high-risk breast cancer patients: Stromal MCT4 predicts poor clinical outcome in triple-negative breast cancers

10.4161/cc.11.6.19530 · 2012 · External reference

Colorectal Cancer Cells Refractory to Anti-VEGF Treatment Are Vulnerable to Glycolytic Blockade due to Persistent Impairment of Mitochondria

10.1158/1535-7163.mct-12-1016-t · 2013 · External reference