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References from Fluvoxamine alleviates paclitaxel-induced neurotoxicity. Local targets link to admitted publications; unresolved targets remain external evidence.
Neuropsychologic impact of standard-dose systemic chemotherapy in long-term survivors of breast cancer and lymphoma
10.1200/jco.2002.20.2.485 · 2002 · External reference
Cognitive function in breast cancer patients receiving adjuvant chemotherapy
10.1200/jco.2000.18.14.2695 · 2000 · External reference
Cognitive dysfunction and cancer: which consequences in terms of disease management?
10.1002/pon.1903 · 2011 · External reference
Cognitive deficits after postoperative adjuvant chemotherapy for breast carcinoma
10.1002/(sici)1097-0142(19990201)85:3<640::aid-cncr14>3.0.co;2-g · 1999 · External reference
Cognitive side effects of cancer therapy demonstrate a functional role for adult neurogenesis
10.1016/j.bbr.2011.05.012 · 2012 · External reference
2-Mercaptoethane sulfonate prevents doxorubicin-induced plasma protein oxidation and TNF-alpha release: implications for the reactive oxygen species-mediated mechanisms of chemobrain
10.1016/j.freeradbiomed.2011.03.009 · 2011 · External reference
The possible role of cytokines in chemotherapy-induced cognitive deficits
10.1007/978-1-4419-6306-2_15 · 2010 · External reference
White matter changes in patients with breast cancer treated with high-dose chemotherapy and autologous bone marrow support
1994 · External reference
Longitudinal assessment of chemotherapy-induced structural changes in cerebral white matter and its correlation with impaired cognitive functioning
10.1200/jco.2011.36.8571 · 2012 · External reference
Altered frontocortical, cerebellar, and basal ganglia activity in adjuvant-treated breast cancer survivors 5–10 years after chemotherapy
10.1007/s10549-006-9380-z · 2007 · External reference
Microtubules and actin filaments: dynamic targets for cancer chemotherapy
10.1016/s0955-0674(98)80095-1 · 1998 · External reference
Delayed emotional recovery after taxane-based chemotherapy
10.1002/cncr.23589 · 2008 · External reference
Estimation of paclitaxel biodistribution and uptake in human-derived xenografts in vivo with (18)F-fluoropaclitaxel
2005 · External reference
Activation of the unfolded protein response in Parkinson’s disease
10.1016/j.bbrc.2007.01.043 · 2007 · External reference
Activation of the unfolded protein response is an early event in Alzheimer’s and Parkinson’s disease
10.1159/000334536 · 2012 · External reference
Presenilin-1 mutations downregulate the signalling pathway of the unfolded-protein response
10.1038/70265 · 1999 · External reference
Altered localization of amyloid precursor protein under endoplasmic reticulum stress
10.1016/j.bbrc.2006.03.173 · 2006 · External reference
Involvement of endoplasmic reticulum stress in tauopathy
10.1016/j.bbrc.2012.12.007 · 2013 · External reference
Paclitaxel induces neurotoxicity through endoplasmic reticulum stress
10.1016/j.bbrc.2013.06.057 · 2013 · External reference
A molecular chaperone inducer protects neurons from ER stress
10.1038/sj.cdd.4402276 · 2008 · External reference
Induction of BiP, an ER-resident protein, prevents the neuronal death induced by transient forebrain ischemia in gerbil
10.1016/j.brainres.2008.02.068 · 2008 · External reference
Effect of an inducer of BiP, a molecular chaperone, on endoplasmic reticulum (ER) stress-induced retinal cell death
10.1167/iovs.08-2123 · 2009 · External reference
Regulation of ER molecular chaperone prevents bone loss in a murine model for osteoporosis
10.1007/s00774-009-0117-z · 2010 · External reference
Post-treatment of a BiP inducer prevents cell death after middle cerebral artery occlusion in mice
10.1016/j.neulet.2010.08.015 · 2010 · External reference
Role of endoplasmic reticulum stress in light-induced photoreceptor degeneration in mice
10.1111/jnc.12116 · 2013 · External reference
Fluvoxamine alleviates ER stress via induction of Sigma-1 receptor
10.1038/cddis.2014.301 · 2014 · External reference
Interactions of selective serotonin reuptake inhibitors with subtypes of sigma receptors in rat brain
10.1016/0014-2999(96)00254-3 · 1996 · External reference
Fluoxetine induces apoptosis in ovarian carcinoma cell line OVCAR-3 through reactive oxygen species-dependent activation of nuclear factor-kappaB
10.1111/j.1742-7843.2009.00509.x · 2010 · External reference
Differential induction of apoptosis by antidepressants in glioma and neuroblastoma cell lines: evidence for p-c-Jun, cytochrome c, and caspase-3 involvement
10.1385/jmn:27:1:029 · 2005 · External reference
Antiproliferative effects of fluoxetine on colon cancer cells and in a colonic carcinogen mouse model
10.1371/journal.pone.0050043 · 2012 · External reference
Fluvoxamine attenuated endoplasmic reticulum stress-induced leptin resistance
10.3389/fendo.2012.00012 · 2012 · External reference
Ca(2+) signaling via sigma(1)-receptors: novel regulatory mechanism affecting intracellular Ca(2+) concentration
10.1016/s0022-3565(24)39299-7 · 2000 · External reference
The sigma receptor: evolution of the concept in neuropsychopharmacology
10.2174/157015905774322516 · 2005 · External reference
Regulating ankyrin dynamics: Roles of sigma-1 receptors
10.1073/pnas.98.2.491 · 2001 · External reference
Sigma-1 receptor chaperones at the ER-mitochondrion interface regulate Ca(2+) signaling and cell survival
10.1016/j.cell.2007.08.036 · 2007 · External reference
Sigma receptor ligands: possible application as therapeutic drugs and as radiopharmaceuticals
2006 · External reference
Targeting ligand-operated chaperone sigma-1 receptors in the treatment of neuropsychiatric disorders
10.1517/14728222.2011.560837 · 2011 · External reference
Sigma-1 receptor agonists as therapeutic drugs for cognitive impairment in neuropsychiatric diseases
10.2174/138161212799436476 · 2012 · External reference
The sigma enigma: can sigma receptors provide a novel target for disorders of mood and cognition?
10.4088/jcp.v69n1101 · 2008 · External reference
Effects of repeated milnacipran and fluvoxamine treatment on mechanical allodynia in a mouse paclitaxel-induced neuropathic pain model
10.2220/biomedres.34.105 · 2013 · External reference
Cerebral ischemia and the unfolded protein response
10.1111/j.1471-4159.2004.02703.x · 2004 · External reference