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References from Limited impact of NLRP3 inflammasome deficiency on diet-induced metabolic dysfunction-associated steatohepatitis in mice. Local targets link to admitted publications; unresolved targets remain external evidence.
European association for the Study of Diabetes (EASD), European Association for the Study of Obesity (EASO). EASL-EASD-EASO Clinical Practice Guidelines on the management of metabolic dysfunction-associated steatotic liver disease (MASLD)
10.1016/j.jhep.2024.04.031 · 2024 · External reference
Prevalence, incidence, and outcome of non-alcoholic fatty liver disease in Asia, 1999-2019: a systematic review and meta-analysis
10.1016/s2468-1253(19)30039-1 · 2019 · External reference
Prevalence and associated metabolic factors of nonalcoholic fatty liver disease in the general population from 2014 to 2018 in Japan: a large-scale multicenter retrospective study
10.1111/hepr.13947 · 2023 · External reference
Usefulness of health checkup-based indices in identifying metabolic dysfunction-associated steatotic liver disease
10.1002/jgh3.13110 · 2024 · External reference
Hepatic inflammation and fibrosis are profiles related to mid-term mortality in biopsy-proven MASLD: a multicenter study in Japan
10.1111/apt.17995 · 2024 · External reference
Long-term clinical outcomes in steatotic liver disease and incidence of liver-related events, cardiovascular events and all-cause mortality
10.1111/apt.18015 · 2024 · External reference
Evidence-based clinical practice guidelines for nonalcoholic fatty liver disease/nonalcoholic steatohepatitis 2020
10.1007/s00535-021-01796-x · 2021 · External reference
Evidence-based clinical practice guidelines for nonalcoholic fatty liver disease/nonalcoholic steatohepatitis 2020
10.1111/hepr.13688 · 2021 · External reference
The effectiveness and acceptability of Mediterranean diet and calorie restriction in non-alcoholic fatty liver disease (NAFLD): a systematic review and meta-analysis
10.1016/j.clnu.2022.06.037 · 2022 · External reference
Usefulness of a questionnaire for assessing the relationship between eating behavior and steatotic liver disease among Japanese male young adults
10.1038/s41598-024-52797-8 · 2024 · External reference
Metabolic dysfunction-associated steatotic liver disease and the gut microbiome: pathogenic insights and therapeutic innovations
10.1172/jci186423 · 2025 · External reference
NLRP3 inflammasome in hepatic diseases: a pharmacological target
10.1016/j.bcp.2023.115861 · 2023 · External reference
Fatty acid and endotoxin activate inflammasomes in mouse hepatocytes that release danger signals to stimulate immune cells
10.1002/hep.24341 · 2011 · External reference
Inflammasome-mediated dysbiosis regulates progression of NAFLD and obesity
10.1038/nature10809 · 2012 · External reference
Lack of NLRP3-inflammasome leads to gut-liver axis derangement, gut dysbiosis and a worsened phenotype in a mouse model of NAFLD
2017 · External reference
NLRP3 deficiency did not attenuate NASH development under high fat calorie diet plus high fructose and glucose in drinking water
10.1038/s41374-021-00535-3 · 2021 · External reference
Genetic deletion or pharmacologic inhibition of the Nlrp3 inflammasome did not ameliorate experimental NASH
10.1016/j.jlr.2023.100330 · 2023 · External reference
NLRP3 inflammasome blockade reduces liver inflammation and fibrosis in experimental NASH in mice
10.1016/j.jhep.2017.01.022 · 2017 · External reference
NLRP3 deficiency reprograms hepatic glucose metabolism but fails to ameliorate hepatic inflammation and fibrosis in the MCD model
2026 · External reference
An improved mouse model that rapidly develops fibrosis in non-alcoholic steatohepatitis
10.1111/iep.12008 · 2013 · External reference
Establishment of a general NAFLD scoring system for rodent models and comparison to human liver pathology
10.1371/journal.pone.0115922 · 2014 · External reference
Skeletal muscle atrophy is exacerbated by steatotic and fibrotic liver-derived TNF-α in senescence-accelerated mice
10.1111/jgh.16171 · 2023 · External reference
Inhibitory effects of a selective prostaglandin E2 receptor antagonist RQ-15986 on inflammation-related colon tumorigenesis in APC-mutant rats
10.1371/journal.pone.0251942 · 2021 · External reference
Inhibitory effects of astaxanthin on azoxymethane-induced colonic preneoplastic lesions in C57/BL/KsJ-db/db mice
10.1186/s12876-014-0212-z · 2014 · External reference
Liver acid sphingomyelinase inhibits growth of metastatic colon cancer
2013 · External reference
ASK1 inhibition reduces cell death and hepatic fibrosis in an Nlrp3 mutant liver injury model
10.1172/jci.insight.123294 · 2020 · External reference
NOD-like receptor protein 3 activation causes spontaneous inflammation and fibrosis that mimics human NASH
10.1002/hep.32320 · 2022 · External reference
Cell-specific deletion of NLRP3 inflammasome identifies myeloid cells as key drivers of liver inflammation and fibrosis in Murine steatohepatitis
10.1016/j.jcmgh.2022.06.007 · 2022 · External reference
NLRP3 deletion inhibits the non-alcoholic steatohepatitis development and inflammation in kupffer cells induced by palmitic acid
10.1007/s10753-017-0628-z · 2017 · External reference
An overview of the non-canonical inflammasome
10.1016/j.mam.2020.100924 · 2020 · External reference
Matrix metalloproteinases induce extracellular matrix degradation through various pathways to alleviate hepatic fibrosis
10.1016/j.biopha.2023.114472 · 2023 · External reference
Inflammasome activation and function in liver disease
10.1038/nrgastro.2015.94 · 2015 · External reference
Inflammasomes and fibrosis
2021 · External reference
