Research graph
References from Cyclooxygenase-1-sensitive oxidative responses to thromboxane-prostanoid receptor activation during vascular aging and experimental menopause. Local targets link to admitted publications; unresolved targets remain external evidence.
Vascular aging in women
2024 · External reference
From sex hormone decrease to hormonal treatment: impacts on cardiovascular risk with ageing
10.1093/cvr/cvaf086 · 2025 · External reference
Characterizing vascular and hormonal changes in women across the life span: a cross-sectional analysis
10.1152/ajpheart.00373.2024 · 2024 · External reference
Gathering of aging and estrogen withdrawal in vascular dysfunction of senescent accelerated mice
10.1016/j.exger.2010.07.007 · 2010 · External reference
Estrogen and the vascular endothelium: the unanswered questions
10.1210/endocr/bqad079 · 2023 · External reference
Decreased bioavailability of nitric oxide in aorta from ovariectomized senescent mice: role of cyclooxygenase
10.1016/j.exger.2016.01.006 · 2016 · External reference
Estrogen actions in the cardiovascular system
10.1080/13697130903020291 · 2009 · External reference
Mechanisms underlying the influence of oestrogen on cardiovascular physiology in women
10.1113/jp278063 · 2019 · External reference
Estrogen receptor and vascular aging
10.3389/fragi.2021.727380 · 2021 · External reference
Mechanisms involved in the aging-induced vascular dysfunction
10.3389/fphys.2012.00132 · 2012 · External reference
Pharmacological modulation of vascular ageing: a review from VascAgeNet
10.1016/j.arr.2023.102122 · 2023 · External reference
Endothelium-mediated control of vascular tone: COX-1 and COX-2 products
10.1111/j.1476-5381.2011.01276.x · 2011 · External reference
Endothelium-dependent contractions in SHR: a tale of prostanoid TP and IP receptors
10.1111/j.1476-5381.2008.00060.x · 2009 · External reference
Gene expression changes of prostanoid synthases in endothelial cells and prostanoid receptors in vascular smooth muscle cells caused by aging and hypertension
10.1152/physiolgenomics.00136.2007 · 2008 · External reference
Cyclo-oxygenase-1 and -2 contribution to endothelial dysfunction in ageing
10.1038/sj.bjp.0703632 · 2000 · External reference
Pathophysiology of isoprostanes in the cardiovascular system: implications of isoprostane-mediated thromboxane A receptor activation
10.1111/bph.12677 · 2014 · External reference
17β-estradiol decreases vascular tone in cerebral arteries by shifting COX-dependent vasoconstriction to vasodilation
10.1152/ajpheart.00018.2003 · 2003 · External reference
Vascular endothelial estrogen receptor alpha is modulated by estrogen status and related to endothelial function and endothelial nitric oxide synthase in healthy women
10.1210/jc.2009-0278 · 2009 · External reference
Vascular consequences of menopause and hormone therapy: importance of timing of treatment and type of estrogen
10.1016/j.cardiores.2004.12.012 · 2005 · External reference
Vascular effects of estrogenic menopausal hormone therapy
10.2174/157488712799363253 · 2012 · External reference
Hormone replacement therapy and cardiovascular risk in postmenopausal women
10.1093/ehjopen/oeag054 · 2026 · External reference
Endocrine therapy use and cardiovascular risk in postmenopausal breast cancer survivors
10.1136/heartjnl-2020-317510 · 2021 · External reference
Thromboembolic, cardiovascular and overall mortality risks of aromatase inhibitors, compared with tamoxifen treatment: an outpatient-register-based retrospective cohort study
10.1177/1758835920909660 · 2020 · External reference
Role of thromboxane A signaling in endothelium-dependent contractions of arteries
10.1016/j.prostaglandins.2017.11.004 · 2018 · External reference
Thromboxane A: physiology/pathophysiology, cellular signal transduction and pharmacology
10.1016/j.pharmthera.2008.01.001 · 2008 · External reference
Thromboxane and the thromboxane receptor in cardiovascular disease
10.2217/clp.10.11 · 2010 · External reference
Iloprost inhibits superoxide formation and gp91phox expression induced by the thromboxane A analogue U46619, 8-isoprostane Fα, prostaglandin Fα, cytokines and endotoxin in the pig pulmonary artery
10.1038/sj.bjp.0705626 · 2004 · External reference
Thromboxane receptor activates the AMP-activated protein kinase in vascular smooth muscle cells via hydrogen peroxide
10.1161/circresaha.107.163253 · 2008 · External reference
Cyclooxygenases and the cardiovascular system
10.1016/j.pharmthera.2020.107624 · 2021 · External reference
COX-1 and vascular disease
10.1038/clpt.2009.108 · 2009 · External reference
Carotid dysfunction in senescent female mice is mediated by increased α1A-adrenoceptor activity and COX-derived vasoconstrictor prostanoids
10.1152/ajpheart.00495.2022 · 2023 · External reference
The senescence-accelerated mouse (SAM-P8) as a model for the study of vascular functional alterations during aging
10.1007/s10522-007-9108-4 · 2007 · External reference
Aging-related endothelial dysfunction in the aorta from female senescence-accelerated mice is associated with decreased nitric oxide synthase expression
10.1016/j.exger.2013.08.003 · 2013 · External reference
Western-type diet induces senescence, modifies vascular function in non-senescence mice and triggers adaptive mechanisms in senescent ones
10.1016/j.exger.2013.09.004 · 2013 · External reference
Aging enhances contraction to thromboxane A in aorta from female senescence-accelerated mice
10.1007/s11357-011-9337-y · 2013 · External reference
Pharmacological analysis of cyclooxygenase-1 in inflammation
10.1073/pnas.95.22.13313 · 1998 · External reference
The protective effects of estrogen on the cardiovascular system
10.1056/nejm199906103402306 · 1999 · External reference
Vascular actions of estrogens: functional implications
10.1124/pr.107.08002 · 2008 · External reference
Estrogen replacement suppresses a prostaglandin H synthase-dependent vasoconstrictor in rat mesenteric arteries
10.1161/01.res.83.4.388 · 1998 · External reference
Aging negatively affects estrogens-mediated effects on nitric oxide bioavailability by shifting ERα/ERβ balance in female mice
10.1371/journal.pone.0025335 · 2011 · External reference
Endothelial dysfunction and vascular disease – a 30th anniversary update
10.1111/apha.12646 · 2017 · External reference
Vascular NADPH oxidases as drug targets for novel antioxidant strategies
10.1016/j.drudis.2006.04.003 · 2006 · External reference
Role of oxidative stress in atherosclerosis
10.1016/s0002-9149(02)03144-2 · 2003 · External reference
Guidelines for measuring reactive oxygen species and oxidative damage in cells and in vivo
10.1038/s42255-022-00591-z · 2022 · External reference
