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References from Barcoded oligonucleotide system (BOLT) for targeted organ delivery. Local targets link to admitted publications; unresolved targets remain external evidence.
Recent progress in non-native nucleic acid modifications
10.1039/d0cs01430c · 2021 · External reference
Chemistry, structure and function of approved oligonucleotide therapeutics
10.1093/nar/gkad067 · 2023 · External reference
RNAi-based drug design: considerations and future directions
10.1038/s41573-024-00912-9 · 2024 · External reference
Quantifying and mitigating motor phenotypes induced by antisense oligonucleotides in the central nervous system
10.1016/j.ymthe.2024.10.024 · 2024 · External reference
Delivery of oligonucleotides to the liver with GalNAc: from research to registered therapeutic drug
10.1016/j.ymthe.2020.06.015 · 2020 · External reference
RNA therapeutics on the rise
10.1038/d41573-020-00078-0 · 2020 · External reference
Selective tissue targeting of synthetic nucleic acid drugs
10.1172/jci125228 · 2019 · External reference
Expanding RNAi therapeutics to extrahepatic tissues with lipophilic conjugates
10.1038/s41587-022-01334-x · 2022 · External reference
A divalent siRNA chemical scaffold for potent and sustained modulation of gene expression throughout the central nervous system
10.1038/s41587-019-0205-0 · 2019 · External reference
Cholesterol-functionalized DNA/RNA heteroduplexes cross the blood-brain barrier and knock down genes in the rodent CNS
10.1038/s41587-021-00972-x · 2021 · External reference
Targeting the transferrin receptor to transport antisense oligonucleotides across the mammalian blood-brain barrier
10.1126/scitranslmed.adi2245 · 2024 · External reference
Biomolecular coronas provide the biological identity of nanosized materials
10.1038/nnano.2012.207 · 2012 · External reference
Small-molecule discovery through DNA-encoded libraries
10.1038/s41573-023-00713-6 · 2023 · External reference
Encoded combinatorial chemistry
10.1073/pnas.89.12.5381 · 1992 · External reference
Generation and screening of an oligonucleotide-encoded synthetic peptide library
10.1073/pnas.90.22.10700 · 1993 · External reference
DNA-encoded chemical libraries: a comprehensive review with successful stories and future challenges
10.1021/acsptsci.1c00118 · 2021 · External reference
Challenges and prospects of DNA-encoded library data interpretation
10.1021/acs.chemrev.4c00284 · 2024 · External reference
Barcoded nanoparticles for high throughput in vivo discovery of targeted therapeutics
10.1073/pnas.1620874114 · 2017 · External reference
Theranostic barcoded nanoparticles for personalized cancer medicine
10.1038/ncomms13325 · 2016 · External reference
Placenta-tropic VEGF mRNA lipid nanoparticles ameliorate murine pre-eclampsia
10.1038/s41586-024-08291-2 · 2025 · External reference
Assessing the cost-effectiveness of next-generation sequencing as a biomarker testing approach in oncology and policy implications: a literature review
10.1016/j.jval.2024.04.023 · 2024 · External reference
Intravenous administration of blood-brain barrier-crossing conjugates facilitate biomacromolecule transport into central nervous system
2024 · External reference
Advances in oligonucleotide drug delivery
10.1038/s41573-020-0075-7 · 2020 · External reference
Small RNA or oligonucleotide drugs and challenges in evaluating drug-drug interactions
10.3389/fphar.2025.1720361 · 2025 · External reference
Aptamers as targeted therapeutics: current potential and challenges
10.1038/nrd.2016.199 · 2017 · External reference
Clinical trial to compare safety and tolerability between intravenous infusion and bolus intravenous injection of ApTOLL in healthy volunteers
10.1016/j.omtn.2024.102435 · 2025 · External reference
Disposition and pharmacology of a GalNAc3-conjugated ASO targeting human lipoprotein (a) in mice
10.1038/mtna.2016.26 · 2016 · External reference
Statistics corner: a guide to appropriate use of correlation coefficient in medical research
2012 · External reference
Biostatistics primer: part 2
10.1177/011542650802300176 · 2008 · External reference
Potent and durable gene modulation in heart and muscle with chemically defined lipophilic siRNAs
10.1093/nar/gkaf1374 · 2025 · External reference
Mechanisms of palmitic acid-conjugated antisense oligonucleotide distribution in mice
10.1093/nar/gkaa164 · 2020 · External reference
Tau-targeting antisense oligonucleotide MAPT(Rx) in mild Alzheimer's disease: a phase 1b, randomized, placebo-controlled trial
10.1038/s41591-023-02326-3 · 2023 · External reference
Lipid nanoparticle screening in nonhuman primates with minimal loss of life
2025 · External reference
Conjugation of hydrophobic moieties enhances potency of antisense oligonucleotides in the muscle of rodents and non-human primates
2019 · External reference