Research graph
References from Micellar LYTAC-engineered bionic coatings abrogate RANK-dependent osteocatabolism and boost fibrillogenesis-mimetic mineral accretion for empowering osteoporotic osseointegration. Local targets link to admitted publications; unresolved targets remain external evidence.
Bridging research and application: Zn-Based alloys as next-generation biodegradable orthopedic implants
2025 · External reference
Additive manufacturing for biomedical bone implants: shaping the future of bones
10.1016/j.mser.2025.100931 · 2025 · External reference
Recent advances in biopolymeric composite materials: future sustainability of bone-implant
10.1016/j.rser.2021.111505 · 2021 · External reference
Static topographical cue combined with dynamic fluid stimulation enhances the macrophage extracellular vesicle yield and therapeutic potential for bone defects
10.1021/acsnano.4c15201 · 2025 · External reference
Advanced surface engineering of titanium materials for biomedical applications: from static modification to dynamic responsive regulation
2023 · External reference
Fishnet-Inspired 3D scaffold fabricated from mesh-like electrospun membranes promoted osteoporotic bone regeneration
10.1007/s42765-024-00451-3 · 2025 · External reference
Osteoclasts recycle via osteomorphs during RANKL-stimulated bone resorption
10.1016/j.cell.2021.03.010 · 2021 · External reference
RANKL-responsive epigenetic mechanism reprograms macrophages into bone-resorbing osteoclasts
10.1038/s41423-022-00959-x · 2022 · External reference
Mapping RANKL- and OPG-expressing cells in bone tissue: the bone surface cells as activators of osteoclastogenesis and promoters of the denosumab rebound effect
10.1038/s41413-024-00362-4 · 2024 · External reference
The role of bone in whole-body energy metabolism
10.1038/s41574-025-01162-4 · 2025 · External reference
Effects of targeted therapies on bone in rheumatic and musculoskeletal diseases
10.1038/s41584-022-00764-w · 2022 · External reference
Targeting Msx2 as a brake in the fusion fate of osteoclasts and an anabolic therapy in pre-clinical models of osteoporosis
2025 · External reference
Mechanisms of bone development and repair
10.1038/s41580-020-00279-w · 2020 · External reference
Binding-induced fibrillogenesis peptide inhibits RANKL-mediated osteoclast activation against osteoporosis
10.1016/j.biomaterials.2023.122331 · 2023 · External reference
Receptor activator of nuclear factor Kappa-B-Expressing mesenchymal stem cells-derived extracellular vesicles for osteoporosis therapy
10.1021/acsnano.4c12064 · 2024 · External reference
Bench to bedside: elucidation of the OPG–RANK–RANKL pathway and the development of denosumab
10.1038/nrd3705 · 2012 · External reference
Osteoporosis treatment: recent developments and ongoing challenges
10.1016/s2213-8587(17)30188-2 · 2017 · External reference
Mechanisms underlying the long-term and withdrawal effects of denosumab therapy on bone
10.1038/s41584-023-00935-3 · 2023 · External reference
Denosumab discontinuation in the clinic: implications of rebound bone turnover and emerging strategies to prevent bone loss and fractures
10.1093/jbmr/zjaf037 · 2025 · External reference
Long-term and sequential treatment for osteoporosis
10.1038/s41574-023-00866-9 · 2023 · External reference
PROTACs: past, present and future
10.1039/d2cs00193d · 2022 · External reference
Chemistries of bifunctional PROTAC degraders
10.1039/d2cs00220e · 2022 · External reference
Lysosome-targeting chimaeras for degradation of extracellular proteins
10.1038/s41586-020-2545-9 · 2020 · External reference
LYTACs that engage the asialoglycoprotein receptor for targeted protein degradation
10.1038/s41589-021-00770-1 · 2021 · External reference
Elucidating the cellular determinants of targeted membrane protein degradation by lysosome-targeting chimeras
10.1126/science.adf6249 · 2023 · External reference
Development of integrin-facilitated bispecific aptamer Chimeras for membrane protein degradation
10.1021/jacs.4c04794 · 2024 · External reference
Covalent LYTAC enabled by DNA aptamers for immune checkpoint degradation therapy
2023 · External reference
Aptamer-LYTACs for targeted degradation of extracellular and membrane proteins
2023 · External reference
PDGF-BB secreted by preosteoclasts induces angiogenesis during coupling with osteogenesis
10.1038/nm.3668 · 2014 · External reference
Endocytosis-Independent and cancer-selective cytosolic protein delivery via reversible tagging with LAT1 substrate
10.1002/adma.202110560 · 2022 · External reference
Strong, spontaneous, and self-healing Poly(Ionic liquid) elastomer underwater adhesive with borate ester dynamic crosslinking
10.1002/adma.202413901 · 2024 · External reference
Dynamic borate ester bond-based 3D printing fluorescence polysiloxane with self-healing, antimicrobial, and shape memory
10.1016/j.cej.2024.149850 · 2024 · External reference
Decoupling the effects of nanopore size and surface roughness on the attachment, spreading and differentiation of bone marrow-derived stem cells
10.1016/j.biomaterials.2020.120014 · 2020 · External reference
The synergistic effect of 3D-printed microscale roughness surface and nanoscale feature on enhancing osteogenic differentiation and rapid osseointegration
10.1016/j.jmst.2019.12.030 · 2021 · External reference
Mechanically adaptive mg-ti composites guided by single-cell insights accelerate load-bearing bone regeneration via dual modulation of osteogenesis and osteoclastogenesis
2026 · External reference
Bone-targeted pH-responsive cerium nanoparticles for anabolic therapy in osteoporosis
2021 · External reference
Unresolved reference
External reference
Regulating obesity-induced osteoarthritis by targeting p53-FOXO3, osteoclast ferroptosis, and mesenchymal stem cell adipogenesis
2025 · External reference
Constructions of ROS-responsive titanium-hydroxyapatite implant for mesenchymal stem cell recruitment in peri-implant space and bone formation in osteoporosis microenvironment
2022 · External reference
Piezocatalytically-induced controllable mineralization scaffold with bone-like microenvironment to achieve endogenous bone regeneration
10.1016/j.scib.2024.04.002 · 2024 · External reference
Self-Strengthening adhesive force promotes cell mechanotransduction
10.1002/adma.202006986 · 2020 · External reference
Biomaterial design for regenerating aged bone: materiobiological advances and paradigmatic shifts
10.1093/nsr/nwae076 · 2024 · External reference
