Research graph
References from A dual-responsive hydrogel enables integrated regulation of the neuro-osseous axis by geniposide and strontium ions for bone defect repair. Local targets link to admitted publications; unresolved targets remain external evidence.
Accelerated bone healing via electrical stimulation
2025 · External reference
Osteoking promotes bone formation and bone defect repair through Zbp1-Stat1-Pkr-Mlkl-mediated necroptosis
10.1186/s13020-024-00883-4 · 2024 · External reference
Convergence of scaffold-guided bone regeneration principles and microvascular tissue transfer surgery
10.1126/sciadv.add6071 · 2023 · External reference
Selective promotion of sensory innervation-mediated immunoregulation for tissue repair
10.1126/sciadv.ads9581 · 2025 · External reference
Glycoprotein injectable hydrogels promote accelerated bone regeneration through angiogenesis and innervation
2023 · External reference
Dual-metal-organic framework and gallic acid incorporated 3D-printed scaffolds: revolutionizing refractory bone defect repair through immune-angiogenic-neurogenic synergy
2025 · External reference
Mild photothermal-mediated neuroimmunomodulatory composite hydrogel ameliorates bone healing microenvironment for enhanced osteoporotic bone defect regeneration
2025 · External reference
Nanoarchitecture-integrated hydrogel boosts angiogenesis-osteogenesis-neurogenesis tripling for infected bone fracture healing
2024 · External reference
Copper ion-modified germanium phosphorus Nanosheets integrated with an electroactive and biodegradable hydrogel for neuro-vascularized bone regeneration
10.1002/adhm.202301151 · 2023 · External reference
Injectable dual drug-loaded thermosensitive liposome-hydrogel composite scaffold for vascularised and innervated bone regeneration
10.1016/j.colsurfb.2024.114203 · 2025 · External reference
Biomimetic bone-periosteum scaffold for spatiotemporal regulated innervated bone regeneration and therapy of osteosarcoma
10.1186/s12951-024-02430-7 · 2024 · External reference
Neuropharmacological insights into Gardenia Jasminoides Ellis: harnessing therapeutic potential for central nervous system disorders
10.1016/j.phymed.2024.155374 · 2024 · External reference
Therapeutic potential of catalpol and geniposide in Alzheimer’s and Parkinson’s diseases: a snapshot of their underlying mechanisms
10.1016/j.brainresbull.2021.06.020 · 2021 · External reference
Optimized processing of Gardenia fruits with ginger juice: unveiling therapeutic mechanisms for cholestatic liver injury through Tlr4/Nf-Κb, Fxr/Ppar-α, and Pi3K/Akt/Gsk-3β
10.1371/journal.pone.0330189 · 2025 · External reference
Geniposide ameliorates glucocorticoid-induced osteoblast apoptosis by activating autophagy
10.1016/j.biopha.2022.113829 · 2022 · External reference
Brake-drive osteo system: sequential modulation of the inflammatory microenvironment and osteogenesis for osteoporotic bone defect regeneration
10.1002/adma.72909 · 2026 · External reference
Synthesis and biological evaluation of geniposide derivatives as inhibitors of hyperuricemia, inflammatory and fibrosis
10.1016/j.ejmech.2022.114379 · 2022 · External reference
A multi-herb-combined remedy to overcome hyper-inflammatory response by reprogramming transcription factor profile and shaping monocyte subsets
10.1016/j.phrs.2021.105617 · 2021 · External reference
Microrna-146a-loaded magnesium silicate nanospheres promote bone regeneration in an inflammatory microenvironment
10.1038/s41413-023-00299-0 · 2024 · External reference
Local H(2) release remodels senescence microenvironment for improved repair of injured bone
10.1038/s41467-023-43618-z · 2023 · External reference
Acceleration of bone repairation by Bmscs overexpressing Ngf combined with Nsa and allograft bone scaffolds
10.1186/s13287-024-03807-z · 2024 · External reference
Gelma-based bioactive hydrogel scaffolds with multiple bone defect repair functions: therapeutic strategies and recent advances
10.1186/s40824-023-00422-6 · 2023 · External reference
Three-dimensional bioprinted scaffolds loaded with multifunctional magnesium-based metal-organic frameworks improve the senescence microenvironment prompting aged bone defect repair
10.1021/acsnano.5c03023 · 2025 · External reference
A composite hydrogel functionalized by borosilicate bioactive glasses and Vegf for critical-size bone regeneration
2024 · External reference
Osteoblastic and anti-osteoclastic activities of strontium-substituted silicocarnotite ceramics: in vitro and in vivo studies
2020 · External reference
Sr-incorporated bioactive glass remodels the immunological microenvironment by enhancing the mitochondrial function of macrophage via the Pi3K/Akt/Mtor signaling pathway
10.1021/acsbiomaterials.4c00228 · 2024 · External reference
Black phosphorus tagged responsive strontium hydrogel particles for bone defect repair
2025 · External reference
3D-printed functionalized strontium-silk fibroin-hydroxyapatite scaffolds facilitate bone regeneration via immunomodulatory and sequential Angiogenic-osteogenic coupling
2026 · External reference
Engineering immunomodulatory and osteoinductive implant surfaces via mussel adhesion-mediated ion coordination and molecular clicking
10.1038/s41467-021-27816-1 · 2022 · External reference
Injectable cellular vesicle-based bone meal for inflammatory bone defect repair through restoring immune homeostasis
10.7150/thno.110795 · 2025 · External reference
Decorated polyetheretherketone implants with antibacterial and antioxidative effects through layer-by-layer nanoarchitectonics facilitate diabetic bone integration with infection
10.1021/acsami.2c11574 · 2022 · External reference
Indole-3-propionic acid promotes Schwann cell proliferation following peripheral nerve injury by activating the Pi3K/Akt pathway
10.1016/j.neurot.2025.e00578 · 2025 · External reference
Partial reprogramming in senescent Schwann cells enhances peripheral nerve regeneration via restoration of stress granule homeostasis
10.4028/b-xdtcg5 · 2025 · External reference
Osteoimmunity-regulating biomimetically hierarchical scaffold for augmented bone regeneration
2022 · External reference
Engineered sensory nerve guides self-adaptive bone healing via Ngf-Trka signaling pathway
2023 · External reference
Micro/nanobiomimetic iron-based scaffold induces vascularized bone regeneration to repair large segmental bone defect in load-bearing sites
10.1021/acsnano.4c11960 · 2025 · External reference
Prp-related biomaterials enhance bone and nerve repair
2026 · External reference
Novel “hot spring”-mimetic scaffolds for sequential neurovascular network reconstruction and osteoporosis reversion
10.1016/j.biomaterials.2025.123191 · 2025 · External reference
Photosensitive and conductive hydrogel induced innerved bone regeneration for infected bone defect repair
2023 · External reference
Sensory nerve regulation via H3K27 demethylation revealed in Akermanite composite microspheres repairing maxillofacial bone defect
10.1002/advs.202400242 · 2024 · External reference
Advances of Schwann cells in peripheral nerve regeneration: from mechanism to cell therapy
10.1016/j.biopha.2024.116645 · 2024 · External reference
Multifunctional hydrogel loaded with 4-Octyl Itaconate and exosomes to induce bone regeneration for diabetic infected bone defect via Keap1-Nrf2 pathway
2025 · External reference
Gene delivery of chitosan-graft-polyethyleneimine vectors loaded on scaffolds for nerve regeneration
10.1016/j.carbpol.2022.119499 · 2022 · External reference
Self-assembling peptide hydrogels functionalized with ln- and Bdnf- mimicking epitopes synergistically enhance peripheral nerve regeneration
10.7150/thno.44276 · 2020 · External reference
Myokines and osteokines in aging-related degenerative diseases: regulatory networks in the muscle-bone-brain axis
10.1016/j.cytogfr.2025.09.001 · 2025 · External reference
High-strength gelatin hydrogel scaffold with drug loading remodels the inflammatory microenvironment to enhance osteoporotic bone repair
10.1002/adma.202501051 · 2025 · External reference
Activating macrophage continual efferocytosis via microenvironment biomimetic short fibers for reversing inflammation in bone repair
10.1002/adma.202402968 · 2024 · External reference
Calcium phosphate nanoparticle-immobilized macrophage-derived extracellular vesicle nanohybrid facilitates diabetic bone regeneration
10.1002/adma.202509410 · 2026 · External reference
Lutein-loaded multifunctional hydrogel dressing based on carboxymethyl chitosan for chronic wound healing
10.1016/j.ijbiomac.2025.140219 · 2025 · External reference
New insights into heavy metal sequestration through metal-phenolic network-confined Nano-Hfo: overlooking iron utilization and modulating electron density
2025 · External reference
Microenvironment-responsive metal-phenolic network release platform with Ros scavenging, anti-pyroptosis, and Ecm regeneration for intervertebral disc degeneration
2024 · External reference
Punch shear test for quantitative evaluation of bone defect repair in Wistar rat tibia
10.1016/j.injury.2021.02.015 · 2021 · External reference
Composite biomaterial as a carrier for bone-active substances for metaphyseal tibial bone defect reconstruction in rats
10.1089/ten.tea.2017.0040 · 2017 · External reference
