Research graph
References from Mesenchymal stem cells and their exosomes modulate sebocyte fate and lipid-associated proteomic–lipidomic remodeling. Local targets link to admitted publications; unresolved targets remain external evidence.
The sebaceous gland: a key player in the balance between homeostasis and inflammatory skin diseases
10.3390/cells14100747 · 2025 · External reference
Sebaceous immunobiology-skin homeostasis, pathophysiology, coordination of innate immunity and inflammatory response and disease associations
10.3389/fimmu.2022.1029818 · 2022 · External reference
Acne vulgaris (Primer)
10.1038/nrdp.2015.29 · 2015 · External reference
Seborrheic dermatitis: etiology, risk factors, and treatments:: facts and controversies
10.1016/j.clindermatol.2013.01.001 · 2013 · External reference
Spatial transcriptomics reveals altered lipid metabolism and inflammation-related gene expression of sebaceous glands in psoriasis and atopic dermatitis
10.3389/fimmu.2024.1334844 · 2024 · External reference
Use of lipidomics to investigate sebum dysfunction in juvenile acne
10.1194/jlr.m067942 · 2016 · External reference
Comprehensive analysis of the major lipid classes in sebum by rapid resolution high-performance liquid chromatography and electrospray mass spectrometry
10.1194/jlr.d008391 · 2010 · External reference
Lipidomics of facial sebum in the comparison between acne and non-acne adolescents with dark skin
2021 · External reference
Mesenchymal stem cells in treating human diseases: molecular mechanisms and clinical studies
10.1038/s41392-025-02313-9 · 2025 · External reference
The role and prospects of mesenchymal stem cells in skin repair and regeneration
10.3390/biomedicines12040743 · 2024 · External reference
Polyethylene glycol (PEG)-based precipitation for exosome enrichment: a review on recent developments, current challenges, and future perspectives
2025 · External reference
Extracellular vesicle isolation as an analytical determinant in mass spectrometry-based omics: a review
2026 · External reference
Clinical applications of stem cell-derived exosomes
10.1038/s41392-023-01704-0 · 2024 · External reference
Nanotherapeutics in cancer therapy: targeted delivery-based diagnosis and treatment of cancers
2026 · External reference
Exosomes from adipose-derived stem cells activate sebocytes through the PI3K/AKT/SREBP-1 pathway to accelerate wound healing
10.1007/s00441-024-03872-z · 2024 · External reference
Human mesenchymal stem cell-derived exosomes promote the proliferation and melanogenesis of primary melanocytes by attenuating the H2O2-related cytotoxicity in vitro
10.2147/ccid.s446676 · 2024 · External reference
Topical moisturizer with rose stem cell-derived exosomes (RSCEs) for recalcitrant seborrheic dermatitis: a case report with 6 months of follow-up
10.1111/jocd.16389 · 2024 · External reference
Adipose-derived stem cells attenuate acne-related inflammation via suppression of NLRP3 inflammasome
10.1186/s13287-022-03007-7 · 2022 · External reference
Comprehensive phosphoproteomic profiling of the signaling network in mesenchymal stem cells upon dimethyl fumarate treatment
10.1186/s40543-025-00493-1 · 2025 · External reference
Adjusting batch effects in microarray expression data using empirical Bayes methods
10.1093/biostatistics/kxj037 · 2007 · External reference
Lipid extraction by methyl-tert-butyl ether for high-throughput lipidomics
10.1194/jlr.d700041-jlr200 · 2008 · External reference
Long-chain ceramides are cell non-autonomous signals linking lipotoxicity to endoplasmic reticulum stress in skeletal muscle
10.1038/s41467-022-29363-9 · 2022 · External reference
The sphingolipids change in exosomes from cancer patients and association between exosome release and sphingolipids level based on a pseudotargeted lipidomics method
10.1016/j.aca.2024.342527 · 2024 · External reference
The secretion profile of mesenchymal stem cells and potential applications in treating human diseases
10.1038/s41392-022-00932-0 · 2022 · External reference
Effects of mesenchymal stem cell-derived paracrine signals and their delivery strategies
10.1002/adhm.202001689 · 2021 · External reference
Mesenchymal stem cell-derived exosomes: toward cell-free therapeutic strategies in regenerative medicine
10.4252/wjsc.v12.i8.814 · 2020 · External reference
The crosstalk: exosomes and lipid metabolism
10.1186/s12964-020-00581-2 · 2020 · External reference
Mesenchymal stem cell secreted-extracellular vesicles are involved in chondrocyte production and reduce adipogenesis during stem cell differentiation
10.1007/s13770-022-00490-0 · 2022 · External reference
PLIN2, the major perilipin regulated during sebocyte differentiation, controls sebaceous lipid accumulation in vitro and sebaceous gland size in vivo
10.1016/j.bbagen.2013.05.016 · 2013 · External reference
TGFβ signaling regulates lipogenesis in human sebaceous glands cells
10.1186/1471-5945-13-2 · 2013 · External reference
The role of specific retinoid receptors in sebocyte growth and differentiation in culture
10.1046/j.1523-1747.2000.00868.x · 2000 · External reference
Organizing the cell cortex: the role of ERM proteins
10.1038/nrm2866 · 2010 · External reference
Focal adhesions: what’s new inside
10.1016/j.ydbio.2006.03.029 · 2006 · External reference
The role of palladin in actin organization and cell motility
10.1016/j.ejcb.2008.01.010 · 2008 · External reference
Non-muscle myosin II takes centre stage in cell adhesion and migration
10.1038/nrm2786 · 2009 · External reference
The perilipin family of lipid droplet proteins: gatekeepers of intracellular lipolysis
2017 · External reference
Thematic review series: skin lipids. Sebaceous gland lipids: friend or foe?
10.1194/jlr.r700015-jlr200 · 2008 · External reference
A century of cholesterol and coronaries: from plaques to genes to statins
10.1016/j.cell.2015.01.036 · 2015 · External reference
Exosome/microvesicle-mediated epigenetic reprogramming of cells
2010 · External reference
Mesenchymal stem cell exosomes
2015 · External reference
Concise review: MSC-derived exosomes for cell-free therapy
10.1002/stem.2575 · 2017 · External reference
Mesenchymal stem cell-derived exosomes increase ATP levels, decrease oxidative stress and activate PI3K/Akt pathway to enhance myocardial viability and prevent adverse remodeling after myocardial ischemia/reperfusion injury
10.1016/j.scr.2013.01.002 · 2013 · External reference
Mammalian wax biosynthesis: I. Identification of two fatty acyl-coenzyme A reductases with different substrate specificities and tissue distributions
10.1074/jbc.m406225200 · 2004 · External reference
Peroxisomal disorders: the single peroxisomal enzyme deficiencies
10.1016/j.bbamcr.2006.08.010 · 2006 · External reference
Structure and function of focal adhesions
10.1016/j.ceb.2011.11.001 · 2012 · External reference
Diverse functions of Tim50, a component of the mitochondrial inner membrane protein translocase
10.3390/ijms22157779 · 2021 · External reference
Caveolin-1 expression and cavin stability regulate caveolae dynamics in adipocyte lipid store fluctuation
10.2337/db13-1961 · 2014 · External reference
Cavin family proteins and the assembly of caveolae
10.1242/jcs.167866 · 2015 · External reference
Exosome: a novel and safer therapeutic refinement of mesenchymal stem cell
2013 · External reference
Loss of Sec-1 family domain-containing 1 (Scfd1) causes severe cardiac defects and endoplasmic reticulum stress in zebrafish
10.3390/jcdd10100408 · 2023 · External reference
Utilizing untargeted lipidomics technology to elucidate differences in lipid compositions among sensitive dry, sensitive oily and healthy skin types
10.3390/metabo15050292 · 2025 · External reference
Ferrocene-based glycan labeling for advanced glycomics and mass spectrometry
2025 · External reference