Research graph
References from Harnessing ultrasound-stimulated phase change contrast agents to improve antibiotic efficacy against methicillin-resistant Staphylococcus aureus biofilms. Local targets link to admitted publications; unresolved targets remain external evidence.
Vital signs: epidemiology and recent trends in methicillin-resistant and in methicillin-susceptible Staphylococcus aureus bloodstream infections - United States
10.15585/mmwr.mm6809e1 · 2019 · External reference
Epidemiology of methicillin-resistant Staphylococcus aureus
10.1086/533590 · 2008 · External reference
Changes in prevalence of health care-associated infections in U.S. Hospitals
10.1056/nejmoa1801550 · 2018 · External reference
Staphylococcus aureus-associated skin and soft tissue infections: anatomical localization, epidemiology, therapy and potential prophylaxis
2017 · External reference
The in vivo biofilm
10.1016/j.tim.2013.06.002 · 2013 · External reference
Pseudomonas aeruginosa biofilms in the respiratory tract of cystic fibrosis patients
10.1002/ppul.21011 · 2009 · External reference
The consequences of being in an infectious biofilm: microenvironmental conditions governing antibiotic tolerance
10.3390/ijms18122688 · 2017 · External reference
Physiological heterogeneity in biofilms
10.1038/nrmicro1838 · 2008 · External reference
Antibiotic resistance of bacteria in biofilms
10.1016/s0140-6736(01)05321-1 · 2001 · External reference
Riddle of biofilm resistance
10.1128/aac.45.4.999-1007.2001 · 2001 · External reference
Mechanisms of biofilm resistance to antimicrobial agents
10.1016/s0966-842x(00)01913-2 · 2001 · External reference
Antimicrobial tolerance and metabolic adaptations in microbial biofilms
10.1016/j.tim.2019.05.003 · 2019 · External reference
Persister cells
10.1146/annurev.micro.112408.134306 · 2010 · External reference
How antibiotics kill bacteria: from targets to networks
10.1038/nrmicro2333 · 2010 · External reference
Convergence of Staphylococcus aureus persister and biofilm Research: can biofilms Be defined as communities of adherent persister cells?
10.1371/journal.ppat.1006012 · 2016 · External reference
Bacterial persister cell formation and dormancy
10.1128/aem.02636-13 · 2013 · External reference
Multidrug tolerance of biofilms and persister cells
2008 · External reference
Strategies for combating persister cell and biofilm infections
10.1111/1751-7915.12774 · 2017 · External reference
Activated ClpP kills persisters and eradicates a chronic biofilm infection
10.1038/nature12790 · 2013 · External reference
Chemical induction of aminoglycoside uptake overcomes antibiotic tolerance and resistance in Staphylococcus aureus
10.1016/j.chembiol.2019.07.009 · 2019 · External reference
A combined pharmacodynamic quantitative and qualitative model reveals the potent activity of daptomycin and delafloxacin against Staphylococcus aureus biofilms
10.1128/aac.00181-13 · 2013 · External reference
Pseudomonas aeruginosa exoproducts determine antibiotic efficacy against Staphylococcus aureus
10.1371/journal.pbio.2003981 · 2017 · External reference
Penetration of antibiotics through Staphylococcus aureus and Staphylococcus epidermidis biofilms
10.1093/jac/dkq257 · 2010 · External reference
Penetration barrier contributes to bacterial biofilm-associated resistance against only select antibiotics, and exhibits genus-, strain- and antibiotic-specific differences
10.1093/femspd/ftw056 · 2016 · External reference
Importance of the exopolysaccharide matrix in antimicrobial tolerance of Pseudomonas aeruginosa aggregates
10.1128/aac.02696-16 · 2017 · External reference
The extracellular matrix protects Pseudomonas aeruginosa biofilms by limiting the penetration of tobramycin
10.1111/1462-2920.12155 · 2013 · External reference
Ultrasound-enhanced transdermal delivery: recent advances and future challenges
10.4155/tde.14.32 · 2014 · External reference
Ultrasound-induced blood-brain barrier opening
10.2174/138920112800624364 · 2012 · External reference
“Stable” inertial cavitation
10.1016/s0301-5629(01)00441-0 · 2001 · External reference
Ultrasound and microbubble guided drug delivery: mechanistic understanding and clinical implications
2013 · External reference
Liposome-mediated gentamicin delivery: development and activity against resistant strains of Pseudomonas aeruginosa isolated from cystic fibrosis patients
10.1093/jac/dkh518 · 2005 · External reference
Biofilm penetration, triggered release and in vivo activity of inhaled liposomal amikacin in chronic Pseudomonas aeruginosa lung infections
10.1093/jac/dkn059 · 2008 · External reference
A comparison of sonothrombolysis in aged clots between low-boiling-point phase-change nanodroplets and microbubbles of the same composition
10.1016/j.ultrasmedbio.2020.07.008 · 2020 · External reference
Investigating the accumulation of submicron phase-change droplets in tumors
10.1016/j.ultrasmedbio.2020.06.021 · 2020 · External reference
Accelerated clearance of ultrasound contrast agents containing polyethylene glycol is associated with the generation of anti-polyethylene glycol antibodies
10.1016/j.ultrasmedbio.2018.02.006 · 2018 · External reference
Acoustic cavitation-mediated delivery of small interfering ribonucleic acids with phase-shift nano-emulsions
10.1016/j.ultrasmedbio.2015.04.002 · 2015 · External reference
Characterization of submicron phase-change perfluorocarbon droplets for extravascular ultrasound imaging of cancer
10.1016/j.ultrasmedbio.2012.10.004 · 2013 · External reference
An evaluation of the sonoporation potential of low-boiling point phase-change ultrasound contrast agents in vitro
10.1186/s40349-017-0085-z · 2017 · External reference
Design of ultrasonically-activatable nanoparticles using low boiling point perfluorocarbons
10.1016/j.biomaterials.2012.01.021 · 2012 · External reference
In vivo assessment of the potential for renal bio-effects from the vaporization of perfluorocarbon phase-change contrast agents
10.1016/j.ultrasmedbio.2017.10.016 · 2018 · External reference
Extracellular DNA shields against aminoglycosides in Pseudomonas aeruginosa biofilms
10.1128/aac.00001-13 · 2013 · External reference
Effect of low-intensity ultrasound upon biofilm structure from confocal scanning laser microscopy observation
10.1016/0142-9612(96)00022-1 · 1996 · External reference
Macrophage responsiveness to therapeutic ultrasound
10.1016/0301-5629(90)90045-e · 1990 · External reference
Low intensity pulsed ultrasound accelerates macrophage phagocytosis by a pathway that requires actin polymerization, Rho, and Src/MAPKs activity
10.1016/j.cellsig.2007.12.005 · 2008 · External reference
Ultrasound-stimulated phase-change contrast agents for transepithelial delivery of macromolecules, toward gastrointestinal drug delivery
10.1016/j.ultrasmedbio.2019.02.004 · 2019 · External reference
Interaction of pseudomonic acid A with Escherichia coli B isoleucyl-tRNA synthetase
10.1042/bj1910209 · 1980 · External reference
Vancomycin resistance in enterococci: reprogramming of the D-ala-D-Ala ligases in bacterial peptidoglycan biosynthesis
10.1016/s1074-5521(00)00116-2 · 2000 · External reference
Evaluation of the extracellular and intracellular activities (human THP-1 macrophages) of telavancin versus vancomycin against methicillin-susceptible, methicillin-resistant, vancomycin-intermediate and vancomycin-resistant Staphylococcus aureus
10.1093/jac/dkl424 · 2006 · External reference
Clinical outcome with oral linezolid and rifampin following recurrent methicillin-resistant Staphylococcus aureus bacteremia despite prolonged vancomycin treatment
2004 · External reference
Effect of coadministration of rifampicin on the pharmacokinetics of linezolid: clinical and animal studies
10.1186/s40780-018-0123-1 · 2018 · External reference
Ca(2+)-Daptomycin targets cell wall biosynthesis by forming a tripartite complex with undecaprenyl-coupled intermediates and membrane lipids
10.1038/s41467-020-15257-1 · 2020 · External reference
Staphylococcus aureus persisters tolerant to bactericidal antibiotics
2012 · External reference
Comparative activities of daptomycin, linezolid, and tigecycline against catheter-related methicillin-resistant Staphylococcus bacteremic isolates embedded in biofilm
10.1128/aac.00350-06 · 2007 · External reference
Clinical practice guidelines by the infectious diseases society of America for the treatment of methicillin-resistant Staphylococcus aureus infections in adults and children: executive summary
10.1093/cid/cir034 · 2011 · External reference
Role of daptomycin in the induction and persistence of the viable but non-culturable state of Staphylococcus aureus biofilms
10.3390/pathogens3030759 · 2014 · External reference
Antibiotic pressure can induce the viable but non-culturable state in Staphylococcus aureus growing in biofilms
10.1093/jac/dkt086 · 2013 · External reference
Treatment strategies for infected wounds
10.3390/molecules23092392 · 2018 · External reference
Antibiotics and bacterial resistance in the 21st century
2014 · External reference
Seven ways to preserve the miracle of antibiotics
10.1093/cid/cit070 · 2013 · External reference
Sonobactericide: an emerging treatment strategy for bacterial infections
10.1016/j.ultrasmedbio.2019.09.011 · 2020 · External reference
USMB-induced synergistic enhancement of aminoglycoside antibiotics in biofilms
10.1016/j.ultras.2016.03.017 · 2016 · External reference
The synergistic bactericidal effect of vancomycin on UTMD treated biofilm involves damage to bacterial cells and enhancement of metabolic activities
10.1038/s41598-017-18496-3 · 2018 · External reference
Stimulated phase-shift acoustic nanodroplets enhance vancomycin efficacy against methicillin-resistant Staphylococcus aureus biofilms
10.2147/ijn.s134525 · 2017 · External reference
Low-frequency ultrasound debridement in chronic wound healing: a systematic review of current evidence
10.1177/2292550317693813 · 2017 · External reference
Low-frequency ultrasound-mediated cytokine transfection enhances T cell recruitment at local and distant tumor sites
10.1073/pnas.1914906117 · 2020 · External reference
Enhanced microbubble contrast agent oscillation following 250 kHz insonation
10.1038/s41598-018-34494-5 · 2018 · External reference
Epidemic community-associated methicillin-resistant Staphylococcus aureus: recent clonal expansion and diversification
10.1073/pnas.0710217105 · 2008 · External reference
Pharmacokinetics and pharmacodynamics of levofloxacin injection in healthy Chinese volunteers and dosing regimen optimization
10.1111/jcpt.12074 · 2013 · External reference
Pharmacokinetic basis for the use of extended interval dosage regimens of gentamicin in neonates
10.1093/jac/dkh261 · 2004 · External reference
Once-daily tobramycin in cystic fibrosis: better for clinical outcome than thrice-daily tobramycin but more resistance development?
10.1093/jac/dkl328 · 2006 · External reference
Pharmacokinetic and pharmacodynamic profile of linezolid in healthy volunteers and patients with Gram-positive infections
2003 · External reference
Population pharmacokinetic modeling of isoniazid, rifampin, and pyrazinamide
10.1128/aac.41.12.2670 · 1997 · External reference
Pharmacokinetics and tolerability of daptomycin at doses up to 12 milligrams per kilogram of body weight once daily in healthy volunteers
10.1128/aac.00247-06 · 2006 · External reference
Formulation and acoustic studies of a new phase-shift agent for diagnostic and therapeutic ultrasound
10.1021/la2013705 · 2011 · External reference
