Research graph
References from Protoporphyrin IX derived from dual-species anaerobic biofilms of Fusobacterium necrophorum and Porphyromonas levii attenuates bovine neutrophil function. Local targets link to admitted publications; unresolved targets remain external evidence.
Biofilms as complex differentiated communities
10.1146/annurev.micro.56.012302.160705 · 2002 · External reference
The biofilm matrix
10.1038/nrmicro2415 · 2010 · External reference
Chapter 67 - biofilm and biofilm control
2020 · External reference
Biofilms: microbial life on surfaces
10.3201/eid0809.020063 · 2002 · External reference
Bacterial biofilms: a common cause of persistent infections
10.1126/science.284.5418.1318 · 1999 · External reference
The neutrophil: constant defender and first responder
10.3389/fimmu.2020.571085 · 2020 · External reference
Destruction of bacterial biofilms by polymorphonuclear neutrophils: relative contribution of phagocytosis, DNA release, and degranulation
10.1177/039139881003300906 · 2010 · External reference
Phagocytosis of staphylococci biofilms by polymorphonuclear neutrophils: S. aureus and S. epidermidis differ with regard to their susceptibility towards the host defense
10.1177/039139880903200905 · 2009 · External reference
Neutrophil extracellular traps confine Pseudomonas aeruginosa ocular biofilms and restrict Brain invasion
10.1016/j.chom.2019.02.007 · 2019 · External reference
The exopolysaccharide alginate protects Pseudomonas aeruginosa biofilm bacteria from IFN-gamma-mediated macrophage killing
10.4049/jimmunol.175.11.7512 · 2005 · External reference
Dynamic interactions of neutrophils and biofilms
10.3402/jom.v6.26102 · 2014 · External reference
Biofilms: an emergent form of bacterial life
10.1038/nrmicro.2016.94 · 2016 · External reference
A crucial role for exopolysaccharide modification in bacterial biofilm formation, immune evasion, and virulence
10.1074/jbc.m411374200 · 2004 · External reference
Exopolysaccharide-repressing small molecules with antibiofilm and antivirulence activity against Pseudomonas aeruginosa
10.1128/aac.01997-16 · 2017 · External reference
Pseudomonas aeruginosa Psl polysaccharide reduces neutrophil phagocytosis and the oxidative response by limiting complement-mediated opsonization
10.1111/j.1462-5822.2011.01704.x · 2012 · External reference
The extracellular polymer substance of Pseudomonas aeruginosa: too slippery for neutrophils to migrate on?
10.1177/039139880803100907 · 2008 · External reference
Antibiotic resistance of bacteria in biofilms
10.1016/s0140-6736(01)05321-1 · 2001 · External reference
Identification and quantification of bovine digital dermatitis-associated microbiota across lesion stages in feedlot beef cattle
10.1128/msystems.00708-21 · 2021 · External reference
Detection of antibodies against Fusobacterium necrophorum and Porphyromonas levii-like species in dairy cattle with papillomatous digital dermatitis
10.1111/j.1348-0421.2010.00220.x · 2010 · External reference
Fusobacterium necrophorum infections in animals: pathogenesis and pathogenic mechanisms
10.1016/j.anaerobe.2005.01.007 · 2005 · External reference
Fusobacterium nucleatum enhances invasion of human gingival epithelial and aortic endothelial cells by Porphyromonas gingivalis
10.1111/j.1574-695x.2008.00481.x · 2008 · External reference
Stimulation of Fusobacterium nucleatum biofilm formation by Porphyromonas gingivalis
10.1111/j.1399-302x.2007.00380.x · 2008 · External reference
Fusobacterium nucleatum supports the growth of Porphyromonas gingivalis in oxygenated and carbon-dioxide-depleted environments
10.1099/00221287-148-2-467 · 2002 · External reference
Coaggregation of Porphyromonas gingivalis and Fusobacterium nucleatum PK 1594 is mediated by capsular polysaccharide and lipopolysaccharide
10.1111/j.1574-6968.2006.00131.x · 2006 · External reference
Synergistic pathogenicity of Porphyromonas gingivalis and Fusobacterium nucleatum in the mouse subcutaneous chamber model
10.1016/j.joen.2008.10.015 · 2009 · External reference
Synergistic biofilm formation by Parvimonas micra and Fusobacterium nucleatum
10.1016/j.anaerobe.2019.102100 · 2020 · External reference
Evidence of mutualism between two periodontal pathogens: Co-operative haem acquisition by the HmuY haemophore of Porphyromonas gingivalis and the cysteine protease interpain A (InpA) of Prevotella intermedia
10.1111/omi.12018 · 2013 · External reference
Pyocycanin, a contributory factor in haem acquisition and virulence enhancement of Porphyromonas gingivalis in the lung
10.1371/journal.pone.0118319 · 2015 · External reference
The periodontopathogen Porphyromonas gingivalis binds iron protoporphyrin IX in the μ-oxo dimeric form: an oxidative buffer and possible pathogenic mechanism
1998 · External reference
Heme acquisition mechanisms of Porphyromonas gingivalis – strategies used in a polymicrobial community in a heme-limited host environment
10.1111/omi.12149 · 2017 · External reference
Hypoxia arising from concerted oxygen consumption by neutrophils and microorganisms in biofilms
10.1093/femspd/fty043 · 2018 · External reference
Antimicrobial resistance determinants among anaerobic bacteria isolated from footrot
10.1016/j.vetmic.2011.11.029 · 2012 · External reference
The Calgary Biofilm Device: new technology for rapid determination of antibiotic susceptibilities of bacterial biofilms
10.1128/jcm.37.6.1771-1776.1999 · 1999 · External reference
Microtiter dish biofilm formation assay
2011 · External reference
Tilmicosin induces apoptosis in bovine peripheral neutrophils in the presence or in the absence of Pasteurella haemolytica and promotes neutrophil phagocytosis by macrophages
10.1128/aac.44.9.2465-2470.2000 · 2000 · External reference
In vitro cell migration and invasion assays
2014 · External reference
Red-light excitation of protoporphyrin IX fluorescence for subsurface tumor detection
10.3171/2017.1.jns162061 · 2018 · External reference
Quantification of protoporphyrin IX accumulation in glioblastoma cells: a new technique
2014 · External reference
Techniques for fluorescence detection of protoporphyrin IX in skin cancers associated with photodynamic therapy
10.1515/plm-2013-0030 · 2013 · External reference
Mixed species biofilms of Fusobacterium necrophorum and Porphyromonas levii impair the oxidative response of bovine neutrophils in vitro
10.1016/j.anaerobe.2017.05.008 · 2017 · External reference
Flavourzyme, an enzyme preparation with industrial relevance: automated nine-step purification and partial characterization of eight enzymes
10.1021/acs.jafc.5b01665 · 2015 · External reference
Characterization of commercially available peptidases in respect of the production of protein hydrolysates with defined compositions using a three-step methodology
10.1016/j.molcatb.2016.02.002 · 2016 · External reference
Human polymorphonuclear leukocyte response to Pseudomonas aeruginosa grown in biofilms
10.1128/iai.58.7.2383-2385.1990 · 1990 · External reference
Some bacterial parameters influencing the neutrophil oxidative burst response to Pseudomonas aeruginosa biofilms
10.1111/j.1699-0463.1992.tb03991.x · 1992 · External reference
Phorbol myristate acetate induction of chemotactic migration of human polymorphonuclear neutrophils
10.1007/bf00916591 · 1993 · External reference
Host defense function in neutrophils from the American bison (Bison bison)
10.1016/s1095-6433(00)00264-6 · 2000 · External reference
IL8 and PMA trigger the regulation of different biological processes in granulocyte activation
10.3389/fimmu.2019.03064 · 2020 · External reference
Leukotoxin operon and differential expressions of the leukotoxin gene in bovine Fusobacterium necrophorum subspecies
10.1016/j.anaerobe.2007.09.001 · 2008 · External reference
Cloning, sequencing, and expression of the leukotoxin gene from Fusobacterium necrophorum
10.1128/iai.69.9.5447-5455.2001 · 2001 · External reference
Biological and biochemical characterization of Fusobacterium necrophorum leukotoxin
10.2460/ajvr.1994.55.04.515 · 1994 · External reference
Fusobacterium necrophorum leukotoxin induces activation and apoptosis of bovine leukocytes
10.1128/iai.70.8.4609-4620.2002 · 2002 · External reference
Comparative gene expression analysis of planktonic Porphyromonas gingivalis ATCC 33277 in the presence of a growing biofilm versus planktonic cells
10.1186/s12866-019-1423-9 · 2019 · External reference
Switch from planktonic to sessile life: a major event in pneumococcal pathogenesis
10.1111/j.1365-2958.2006.05310.x · 2006 · External reference
Pseudomonas aeruginosa displays multiple phenotypes during development as a biofilm
10.1128/jb.184.4.1140-1154.2002 · 2002 · External reference
Dispersed cells represent a distinct stage in the transition from bacterial biofilm to planktonic lifestyles
10.1038/ncomms5462 · 2014 · External reference
Regulation of biofilm exopolysaccharide production by cyclic di-guanosine monophosphate
10.3389/fmicb.2021.730980 · 2021 · External reference
Sensory perception in bacterial cyclic diguanylate signal transduction
10.1128/jb.00433-21 · 2022 · External reference
Extracellular DNA, cell surface proteins and c-di-GMP promote biofilm formation in Clostridioides difficile
10.1038/s41598-020-78437-5 · 2021 · External reference
Identification of novel peptides that stimulate human neutrophils
10.3858/emm.2012.44.2.008 · 2012 · External reference
NADPH-oxidase activation in murine neutrophils via formyl peptide receptors
10.1016/s0014-4827(02)00010-1 · 2003 · External reference
Species variation in neutrophil biochemistry and function
10.1002/jlb.46.1.63 · 1989 · External reference
Oleic and linoleic acids induce the release of neutrophil extracellular traps via pannexin 1-dependent ATP release and P2X1 receptor activation
10.3389/fvets.2020.00260 · 2020 · External reference
Bacterial DNA activates human neutrophils by a CpG-independent pathway
10.1002/eji.200324334 · 2003 · External reference
Induction of reactive oxygen species in bovine neutrophils is CD11b, but not dectin-1-dependent
10.1016/j.vetimm.2010.10.021 · 2011 · External reference
The periodontal pathogen Porphyromonas gingivalis harnesses the chemistry of the μ-oxo bishaem of iron protoporphyrin IX to protect against hydrogen peroxide
2000 · External reference
Protoporphyrin IX: the good, the bad, and the ugly
10.1124/jpet.115.228130 · 2016 · External reference
Heme-induced neutrophil extracellular traps contribute to the pathogenesis of sickle cell disease
10.1182/blood-2013-10-529982 · 2014 · External reference
Heme induces significant neutrophil adhesion in vitro via an nfκb-dependent pathway
10.1182/blood-2018-99-118974 · 2018 · External reference
Neutrophil activation by heme: implications for inflammatory processes
10.1182/blood.v99.11.4160 · 2002 · External reference
Quantitative analysis of hemin-induced neutrophil extracellular trap formation and effects of hydrogen peroxide on this phenomenon
2017 · External reference
Revisiting the putative role of heme as a trigger of inflammation
10.1002/prp2.392 · 2018 · External reference
Hemin inhibits NLRP3 inflammasome activation in sepsis-induced acute lung injury, involving heme oxygenase-1
10.1016/j.intimp.2014.02.017 · 2014 · External reference
Protoporphyrin IX induces a necrotic cell death in human THP-1 macrophages through activation of reactive oxygen species/c-jun N-terminal protein kinase pathway and opening of mitochondrial permeability transition pore
10.1159/000366383 · 2014 · External reference
Determination of porphyrins in oral bacteria by liquid chromatography electrospray ionization tandem mass spectrometry
10.1007/s00216-015-8864-2 · 2015 · External reference
Unresolved reference
2022 · External reference
