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References from In vitro bacterial vaginosis biofilm community manipulation using endolysin therapy. Local targets link to admitted publications; unresolved targets remain external evidence.
The global epidemiology of bacterial vaginosis: a systematic review
10.1016/j.ajog.2013.05.006 · 2013 · External reference
High global burden and costs of bacterial vaginosis: a systematic review and meta-analysis
10.1097/olq.0000000000000972 · 2019 · External reference
Diversity of vaginal microbiome and metabolome during genital infections
10.1038/s41598-019-50410-x · 2019 · External reference
Bacterial vaginosis biofilms: challenges to current therapies and emerging solutions
2015 · External reference
Association of Mobiluncus curtisii with recurrence of bacterial vaginosis
10.1097/olq.0b013e318167b105 · 2008 · External reference
Emended description of Gardnerella vaginalis and description of Gardnerella leopoldii sp. nov., Gardnerella piotii sp. nov. and Gardnerella swidsinskii sp. nov., with delineation of 13 genomic species within the genus Gardnerella
10.1099/ijsem.0.003200 · 2019 · External reference
Recurrent bacterial vaginosis
10.1097/01.npr.0000696904.36628.0a · 2020 · External reference
Host-vaginal microbiota interactions in the pathogenesis of bacterial vaginosis
10.1097/qco.0000000000000620 · 2020 · External reference
Bacterial vaginosis: a review of treatment, recurrence, and disparities
10.1016/j.nurpra.2019.03.010 · 2019 · External reference
Unresolved reference
External reference
Bacteriophage endolysins as novel antimicrobials
10.2217/fmb.12.97 · 2012 · External reference
Identification and characterization of novel endolysins targeting Gardnerella vaginalis biofilms to treat bacterial vaginosis
10.1038/s41522-022-00285-0 · 2022 · External reference
Bacteriophage endolysins: a novel anti-infective to control Gram-positive pathogens
10.1016/j.ijmm.2010.04.002 · 2010 · External reference
Engineered phage endolysin eliminates Gardnerella biofilm without damaging beneficial bacteria in bacterial vaginosis ex vivo
10.3390/pathogens10010054 · 2021 · External reference
Isolation of phage lysins that effectively kill Pseudomonas aeruginosa in mouse models of lung and skin infection
10.1128/aac.00024-19 · 2019 · External reference
Gardnerella vaginalis has a gram-positive cell-wall ultrastructure and lacks classical cell-wall lipopolysaccharide
10.1099/00222615-29-3-229 · 1989 · External reference
Preclinical data on the gardnerella-specific endolysin PM-477 indicate its potential to improve the treatment of bacterial vaginosis through enhanced biofilm removal and avoidance of resistance
10.1128/aac.02319-21 · 2022 · External reference
Exploiting the anti-biofilm effect of the engineered phage endolysin PM-477 to disrupt in vitro single- and dual-species biofilms of vaginal pathogens associated with bacterial vaginosis
10.3390/antibiotics11050558 · 2022 · External reference
Evaluation of different culture media to support in vitro growth and biofilm formation of bacterial vaginosis-associated anaerobes
10.7717/peerj.9917 · 2020 · External reference
Atopobium vaginae and Prevotella bivia are able to incorporate and influence gene expression in a pre-formed Gardnerella vaginalis biofilm
10.3390/pathogens10020247 · 2021 · External reference
Recurrent vulvovaginal candidiasis: a dynamic interkingdom biofilm disease of
10.1128/msystems.00622-21 · 2021 · External reference
Candida albicans as an essential “keystone” component within polymicrobial oral biofilm models?
10.3390/microorganisms9010059 · 2020 · External reference
Agar and broth dilution methods to determine the minimal inhibitory concentration (MIC) of antimicrobial substances
10.1038/nprot.2007.521 · 2008 · External reference
The estimation of the bactericidal power of the blood
1938 · External reference
Unveiling the role of Gardnerella vaginalis in polymicrobial Bacterial Vaginosis biofilms: the impact of other vaginal pathogens living as neighbors
10.1038/s41396-018-0337-0 · 2019 · External reference
Interactions between Lactobacillus crispatus and bacterial vaginosis (BV)-associated bacterial species in initial attachment and biofilm formation
10.3390/ijms140612004 · 2013 · External reference
Assessing the inflammatory response to in vitro polymicrobial wound biofilms in a skin epidermis model
10.1038/s41522-022-00286-z · 2022 · External reference
Viable compositional analysis of an eleven species oral polymicrobial biofilm
2016 · External reference
Candida albicans mycofilms support Staphylococcus aureus colonization and enhances miconazole resistance in dual-species interactions
10.3389/fmicb.2017.00258 · 2017 · External reference
Quantitative PCR assessments of bacterial species in women with and without bacterial vaginosis
10.1128/jcm.00851-09 · 2010 · External reference
High-resolution visualization of the microbial glycocalyx with low-voltage scanning electron microscopy: dependence on cationic dyes
10.1369/jhc.4a6428.2004 · 2004 · External reference
In vitro interactions within a biofilm containing three species found in bacterial vaginosis (BV) support the higher antimicrobial tolerance associated with BV recurrence
10.1093/jac/dkac155 · 2022 · External reference
Etiology of bacterial vaginosis and polymicrobial biofilm formation
10.1080/1040841x.2017.1291579 · 2017 · External reference
Influence of biofilm formation by Gardnerella vaginalis and other anaerobes on bacterial vaginosis
10.1093/infdis/jiv338 · 2015 · External reference
Bacterial vaginosis: drivers of recurrence and challenges and opportunities in partner treatment
10.1186/s12916-021-02077-3 · 2021 · External reference
High recurrence rates of bacterial vaginosis over the course of 12 months after oral metronidazole therapy and factors associated with recurrence
10.1086/503780 · 2006 · External reference
Long-term follow-up of patients with bacterial vaginosis treated with oral metronidazole and topical clindamycin
10.1093/infdis/167.3.783 · 1993 · External reference
Development and characterisation of a novel three-dimensional inter-kingdom wound biofilm model
10.1080/08927014.2016.1252337 · 2016 · External reference
Bacterial vaginosis and health-associated bacteria modulate the immunometabolic landscape in 3D model of human cervix
10.1038/s41522-021-00259-8 · 2021 · External reference
Phage cocktail development for bacteriophage therapy: toward improving spectrum of activity breadth and depth
10.3390/ph14101019 · 2021 · External reference
Current status of endolysin-based treatments against gram-negative bacteria
10.3390/antibiotics10101143 · 2021 · External reference
Biofilm-stimulated epithelium modulates the inflammatory responses in co-cultured immune cells
10.1038/s41598-019-52115-7 · 2019 · External reference
Interkingdom interactions on the denture surface: implications for oral hygiene
2019 · External reference
Optimization of propidium monoazide qPCR (viability-qPCR) to quantify the killing by the gardnerella-specific endolysin PM-477, directly in vaginal samples from women with bacterial vaginosis
10.3390/antibiotics11010111 · 2022 · External reference
A New PNA-FISH probe targeting Fannyhessea vaginae
10.3389/fcimb.2021.779376 · 2021 · External reference
Fluorescence in situ Hybridization method using Peptide Nucleic Acid probes for rapid detection of Lactobacillus and Gardnerella spp
10.1186/1471-2180-13-82 · 2013 · External reference
Six bacterial vaginosis-associated species can form an in vitro and ex vivo polymicrobial biofilm that is susceptible to Thymbra capitata essential oil
10.3389/fcimb.2022.824860 · 2022 · External reference