Research graph
References from Engineering extracellular vesicles for multi-cargo co-delivery in silicosis and related fibrotic diseases: design strategies and translational prospects. Local targets link to admitted publications; unresolved targets remain external evidence.
Silicosis
10.1016/s0140-6736(12)60235-9 · 2012 · External reference
Integration of apaQTL and eQTL analysis reveals novel SNPs associated with occupational pulmonary fibrosis risk
10.1007/s00204-024-03734-1 · 2024 · External reference
Multi-omics and multi-stages integration identified a novel variant associated with silicosis risk
10.1007/s00204-024-03795-2 · 2024 · External reference
Burden of silicosis based on the global burden of disease study 2021: trend analysis of incidence, mortality, and disability-adjusted life years, and projections for the next 30 years
2025 · External reference
A review of silicosis and other silica-related diseases in the engineered stone countertop processing industry
10.1186/s12995-025-00455-8 · 2025 · External reference
From basic research to clinical practice: considerations for treatment drugs for silicosis
2023 · External reference
Silicosis: from pathogenesis to therapeutics
2025 · External reference
The role of inflammation in silicosis
2024 · External reference
Updated insights into the molecular networks for NLRP3 inflammasome activation
10.1038/s41423-025-01284-9 · 2025 · External reference
Mechanistic insights into gasdermin-mediated pyroptosis
10.1038/s41580-025-00837-0 · 2025 · External reference
Inhibition of gasdermin D-dependent pyroptosis attenuates the progression of silica-induced pulmonary inflammation and fibrosis
10.1016/j.apsb.2021.10.006 · 2022 · External reference
Redox regulation: mechanisms, biology and therapeutic targets in diseases
10.1038/s41392-024-02095-6 · 2025 · External reference
The KEAP1-Cullin3-RBX1-Nrf2 axis in redox homeostasis: molecular mechanisms, pathophysiological roles, and precision therapeutic opportunities
10.1007/s12035-025-05313-6 · 2025 · External reference
Cellular and molecular genetic mechanisms of lung fibrosis development and the role of vitamin D: a review
10.3390/ijms25168946 · 2024 · External reference
The impact of oxidative stress and the NRF2-KEAP1-ARE signaling pathway on anticancer drug resistance
10.32604/or.2025.065755 · 2025 · External reference
Targeting TGF-β signal transduction for fibrosis and cancer therapy
10.1186/s12943-022-01569-x · 2022 · External reference
TGF-β signaling: critical nexus of fibrogenesis and cancer
10.1186/s12967-024-05411-4 · 2024 · External reference
The role of macrophage polarization and cellular crosstalk in the pulmonary fibrotic microenvironment: a review
10.1186/s12964-024-01557-2 · 2024 · External reference
TGF-β signaling in health, disease and therapeutics
10.1038/s41392-024-01764-w · 2024 · External reference
Pulmonary fibrosis through the prism of NLRP3 inflammasome: mechanistic pathways and prospective therapeutic innovations
2025 · External reference
Combined therapy with pirfenidone and nintedanib counteracts fibrotic silicosis in mice
10.1111/bph.17390 · 2025 · External reference
The role of inflammasomes in human diseases and their potential as therapeutic targets
10.1038/s41392-023-01687-y · 2024 · External reference
Molecular mechanisms responsible for the therapeutic potential of mesenchymal stem cell-derived exosomes in the treatment of lung fibrosis
10.3390/ijms25084378 · 2024 · External reference
Pulmonary fibrosis and exosomes: pathways to treatment
10.1007/s11033-025-10855-y · 2025 · External reference
The dual role of exosomes in the tumor microenvironment: from pro-tumorigenic signaling to immune modulation
2025 · External reference
10.2174/0929867327666200130103206
10.2174/0929867327666200130103206 · External reference
Immunogenicity of extracellular vesicles
10.1002/adma.202403199 · 2024 · External reference
Engineering exosomes for targeted neurodegenerative therapy: innovations in biogenesis, drug loading, and clinical translation
10.7150/thno.117143 · 2026 · External reference
Leveraging nature's nanocarriers: translating insights from extracellular vesicles to biomimetic synthetic vesicles for biomedical applications
2025 · External reference
Exosomal miRNAs as biomarkers and therapeutic targets in silicosis-related lung fibrosis
10.1007/s11033-025-10687-w · 2025 · External reference
Unpacking the anti-fibrotic arsenal: molecular mechanisms and therapeutic translation of MSC-derived exosomes in pulmonary fibrosis
10.3389/fimmu.2025.1725041 · 2025 · External reference
Engineerable mesenchymal stem cell-derived extracellular vesicles as promising therapeutic strategies for pulmonary fibrosis
10.1186/s13287-025-04490-4 · 2025 · External reference
Linking NLRP3 inflammasome and pulmonary fibrosis: mechanistic insights and promising therapeutic avenues
10.1007/s10787-023-01389-5 · 2024 · External reference
Cryo-EM structures of the active NLRP3 inflammasome disc
10.1038/s41586-022-05570-8 · 2023 · External reference
Structural basis for the oligomerization-facilitated NLRP3 activation
10.1038/s41467-024-45396-8 · 2024 · External reference
Oxidized DNA fragments exit mitochondria via mPTP- and VDAC-dependent channels to activate NLRP3 inflammasome and interferon signaling
10.1016/j.immuni.2022.06.007 · 2022 · External reference
The adaptor ASC has extracellular and “prionoid” activities that propagate inflammation
10.1038/ni.2913 · 2014 · External reference
Suppression of NOX2-derived reactive oxygen species (ROS) reduces epithelial-to-mesenchymal transition through blocking SiO2-regulated JNK activation
10.3390/toxics13050365 · 2025 · External reference
Structure-guided conformational restriction leading to high-affinity, selective, and cell-active tetrahydroisoquinoline-based noncovalent Keap1-Nrf2 inhibitors
10.1021/acs.jmedchem.4c01221 · 2024 · External reference
CH7450924, a KEAP1-NRF2 interaction inhibitor, ameliorates LPS-induced multiple organ dysfunction via inflammatory pathway inhibition
10.1038/s41598-025-20350-w · 2025 · External reference
TXNIP: a key protein in the cellular stress response pathway and a potential therapeutic target
10.1038/s12276-023-01019-8 · 2023 · External reference
Activation of the ROS/TXNIP/NLRP3 pathway disrupts insulin-dependent glucose uptake in skeletal muscle of insulin-resistant obese mice
10.1016/j.freeradbiomed.2024.06.011 · 2024 · External reference
Bicyclol attenuates pulmonary fibrosis with silicosis via both canonical and non-canonical TGF-β1 signaling pathways
10.1186/s12967-024-05399-x · 2024 · External reference
Nerandomilast, a PDE4B inhibitor, alleviates silica-induced lung inflammation and fibrosis by inhibition of NLRP3 inflammasome and TGF-β/smad signalling
10.1111/bph.70240 · 2026 · External reference
Emerging roles of ferroptosis in pulmonary fibrosis: current perspectives, opportunities and challenges
10.1038/s41420-024-02078-0 · 2024 · External reference
Coenzyme Q10 alleviates silicosis fibrosis via inhibiting ferroptosis in mice
10.21873/invivo.13816 · 2025 · External reference
The pivotal role of TGF-β/smad pathway in fibrosis pathogenesis and treatment
2025 · External reference
Modulation of TGF-β signaling new approaches toward kidney disease and fibrosis therapy
10.7150/ijbs.101548 · 2025 · External reference
TGF-β inhibitors: the future for prevention and treatment of liver fibrosis?
2025 · External reference
Structures of TGF-β with betaglycan and signaling receptors reveal mechanisms of complex assembly and signaling
10.1038/s41467-025-56796-9 · 2025 · External reference
Recent advances in therapeutic use of transforming growth factor-beta inhibitors in cancer and fibrosis
10.3389/fonc.2025.1489701 · 2025 · External reference
Structural impact, ligand–protein interactions, and molecular phenotypic effects of TGF-β1 gene variants: in silico analysis with implications for idiopathic pulmonary fibrosis
10.1016/j.gene.2024.148565 · 2024 · External reference
GAMG ameliorates silica-induced pulmonary inflammation and fibrosis via the regulation of EMT and NLRP3/TGF-β1/smad signaling pathway
2024 · External reference
GLP-1R activation attenuates the progression of pulmonary fibrosis via disrupting NLRP3 inflammasome/PFKFB3-driven glycolysis interaction and histone lactylation
10.1186/s12967-024-05753-z · 2024 · External reference
Reciprocal regulation of TGF-β and reactive oxygen species: a perverse cycle for fibrosis
10.1016/j.redox.2015.09.009 · 2015 · External reference
Pulmonary osteoclast-like cells in silica induced pulmonary fibrosis
10.1126/sciadv.adl4913 · 2024 · External reference
Mechanics-activated fibroblasts promote pulmonary group 2 innate lymphoid cell plasticity propelling silicosis progression
10.1038/s41467-024-54174-5 · 2024 · External reference
NLRP3 deficiency abrogates silica-induced neutrophil infiltration, pulmonary damage and fibrosis
10.1186/s12931-025-03192-y · 2025 · External reference
New insights into crosstalk between Nrf2 pathway and ferroptosis in lung disease
10.1038/s41419-024-07224-1 · 2024 · External reference
Nrf2 protects against pulmonary fibrosis by regulating the lung oxidant level and Th1/Th2 balance
10.1186/1465-9921-11-31 · 2010 · External reference
The transcription factor NRF2 protects against pulmonary fibrosis
10.1096/fj.03-1127fje · 2004 · External reference
Prednisone, azathioprine, and N-acetylcysteine for pulmonary fibrosis
10.1056/nejmoa1113354 · 2012 · External reference
The artemis-Ipf Investigators, Treatment of idiopathic pulmonary fibrosis with ambrisentan
10.7326/0003-4819-158-9-201305070-00003 · 2013 · External reference
Inhibition of epithelial cell YAP-TEAD/LOX signaling attenuates pulmonary fibrosis in preclinical models
10.1038/s41467-025-61795-x · 2025 · External reference
Spatial transcriptomic validation of a biomimetic model of fibrosis enables re-evaluation of a therapeutic antibody targeting LOXL2
2024 · External reference
Mapping spatially resolved transcriptomes in human and mouse pulmonary fibrosis
10.1038/s41588-024-01819-2 · 2024 · External reference
Single-cell RNA-seq reveals ectopic and aberrant lung-resident cell populations in idiopathic pulmonary fibrosis
10.1126/sciadv.aba1983 · 2020 · External reference
Spatial transcriptomics identifies molecular niche dysregulation associated with distal lung remodeling in pulmonary fibrosis
10.1038/s41588-025-02080-x · 2025 · External reference
Extracellular matrix anchored neutrophils drive pulmonary fibrosis in mice
2025 · External reference
Exosomal miRNA reprogramming in pyroptotic macrophage drives silica-induced fibroblast-to-myofibroblast transition and pulmonary fibrosis
10.1016/j.jhazmat.2024.136629 · 2025 · External reference
Multi-omics integration reveals a nonlinear signature that precedes progression of lung fibrosis
10.1002/cti2.1485 · 2024 · External reference
Pulmonary fibrosis: pathogenesis and therapeutic strategies
10.1002/mco2.744 · 2024 · External reference
Robustness and resilience of complex networks
10.1038/s42254-023-00676-y · 2024 · External reference
Robustness and lethality in multilayer biological molecular networks
10.1038/s41467-020-19841-3 · 2020 · External reference
Network robustness and fragility: percolation on random graphs
10.1103/physrevlett.85.5468 · 2000 · External reference
Unraveling the priming phase of NLRP3 inflammasome activation: molecular insights and clinical relevance
10.1016/j.intimp.2024.113821 · 2025 · External reference
TXNIP regulates NLRP3 inflammasome-induced pyroptosis related to aging via cAMP/PKA and PI3K/akt signaling pathways
10.1007/s12035-024-04089-5 · 2024 · External reference
A novel crosstalk between Nrf2 and Smad2/3 bridged by two nuanced Keap1 isoforms with their divergent effects on these distinct family transcription factors
10.1016/j.freeradbiomed.2024.01.025 · 2024 · External reference
TXNIP regulates pulmonary inflammation induced by Asian sand dust
10.1016/j.redox.2024.103421 · 2024 · External reference
Targeting epigenetic and post-translational modifications of NRF2: key regulatory factors in disease treatment
10.1038/s41420-025-02491-z · 2025 · External reference
Synergistic regulation of TGF-β1/Smad2/3 signaling and inflammatory pathways via SA/NAC-based nanoplatforms: a novel strategy to enhance anti-fibrotic therapeutic outcomes in idiopathic pulmonary fibrosis
10.1186/s12951-026-04071-4 · 2026 · External reference
Role of TGF-β/SMAD/YAP/TAZ signaling in skeletal muscle fibrosis
10.1152/ajpcell.00541.2024 · 2025 · External reference
NLRP3 inflammasome in health and disease
10.3892/ijmm.2025.5489 · 2025 · External reference
Cellular crosstalk in fibrosis: insights into macrophage and fibroblast dynamics
10.1016/j.jbc.2025.110203 · 2025 · External reference
Regulation of cargo selection in exosome biogenesis and its biomedical applications in cancer
10.1038/s12276-024-01209-y · 2024 · External reference
Extracellular vesicles as tools and targets in therapy for diseases
10.1038/s41392-024-01735-1 · 2024 · External reference
Biology and therapeutic potential of extracellular vesicle targeting and uptake
2026 · External reference
The ins-and-outs of exosome biogenesis, secretion, and internalization
10.1016/j.tcb.2023.06.006 · 2024 · External reference
The role of exosomes in immunopathology and potential therapeutic implications
10.1038/s41423-025-01323-5 · 2025 · External reference
Small molecule inhibitors of hnRNPA2B1–RNA interactions reveal a predictable sorting of RNA subsets into extracellular vesicles
10.1093/nar/gkaf176 · 2025 · External reference
Minimal information for studies of extracellular vesicles (MISEV2023): from basic to advanced approaches
10.1002/jev2.12404 · 2024 · External reference
Macrophage-derived exosomal HMGB3 regulates silica-induced pulmonary inflammation by promoting M1 macrophage polarization and recruitment
10.1186/s12989-024-00568-8 · 2024 · External reference
Exosomes: efficient macrophage-related immunomodulators in chronic lung diseases
10.3389/fcell.2024.1271684 · 2024 · External reference
Macrophage-derived exosomes mediate silica-induced pulmonary fibrosis by activating fibroblast in an endoplasmic reticulum stress-dependent manner
10.1111/jcmm.16524 · 2021 · External reference
Exposure to micron-grade silica particles triggers pulmonary fibrosis through cell-to-cell delivery of exosomal miR-107
10.1016/j.ijbiomac.2024.131058 · 2024 · External reference
The aggravate role of exosomal circRNA11:120406118|12040782 on macrophage pyroptosis through miR-30b-5p/NLRP3 axis in silica-induced lung fibrosis
10.1016/j.intimp.2022.109476 · 2023 · External reference
Immune mechanisms in fibrotic interstitial lung disease
10.1016/j.cell.2024.05.015 · 2024 · External reference
NLRP3 inflammasome mediates abnormal epithelial regeneration and distal lung remodeling in silica-induced lung fibrosis
10.3892/ijmm.2024.5349 · 2024 · External reference
Epithelium-derived exosomes promote silica nanoparticles-induced pulmonary fibroblast activation and collagen deposition via modulating fibrotic signaling pathways and their epigenetic regulations
10.1186/s12951-024-02609-y · 2024 · External reference
Exosome miRNA profile and mitigating effect of miR-23a-3p/Cul3 axis on apoptosis in the pathogenesis of SiO2 dust-induced lung fibrosis
2024 · External reference
Effect of macrophage-to-myofibroblast transition on silicosis
10.1002/ame2.12470 · 2025 · External reference
The novel insights of epithelial-derived exosomes in various fibrotic diseases
2024 · External reference
Engineering macrophage-derived exosome to deliver pirfenidone: a novel approach to combat silicotic pulmonary fibrosis
2025 · External reference
Tumour exosome integrins determine organotropic metastasis
10.1038/nature15756 · 2015 · External reference
Applications of liposomes and lipid nanoparticles in cancer therapy: current advances and prospects
10.1186/s40164-025-00602-1 · 2025 · External reference
Polymeric nanoparticles for drug delivery
10.1021/acs.chemrev.3c00705 · 2024 · External reference
The nanocarrier landscape─evaluating key drug delivery vehicles and their capabilities: a translational perspective
10.1021/acsami.5c07366 · 2025 · External reference
Can therapeutic potency of a cancer nanomedicine be predicted by pain-related behavioral test in subcutaneous tumor model?
2026 · External reference
Exosomes─nature's lipid nanoparticles, a rising star in drug delivery and diagnostics
10.1021/acsnano.2c08774 · 2022 · External reference
Lung single-cell transcriptomics offers insights into the pulmonary interstitial toxicity caused by silica nanoparticles
10.1021/envhealth.4c00052 · 2024 · External reference
Emerging delivery approaches for targeted pulmonary fibrosis treatment
2024 · External reference
Inhalable siRNA targeting IL-11 nanoparticles significantly inhibit bleomycin-induced pulmonary fibrosis
10.1021/acsnano.4c15130 · 2025 · External reference
Inhalable myofibroblast targeting nanoparticles for synergistic treatment of pulmonary fibrosis
2025 · External reference
Extracellular matrix limits nanoparticle diffusion and cellular uptake in a tissue-specific manner
10.1021/acsnano.4c10381 · 2024 · External reference
Realveolarization with inhalable mucus-penetrating lipid nanoparticles for the treatment of pulmonary fibrosis in mice
10.4028/b-wjqrp6 · 2024 · External reference
Polyethylene glycol immunogenicity in nanomedicine
10.1038/s44222-025-00321-6 · 2025 · External reference
mRNA-carrying lipid nanoparticles that induce lysosomal rupture activate NLRP3 inflammasome and reduce mRNA transfection efficiency
10.1039/d2bm00883a · 2022 · External reference
Beyond lipids: exploring advances in polymeric gene delivery in the lipid nanoparticles era
10.1002/adma.202404608 · 2024 · External reference
Biotransformation and biological fate of magnetic iron oxide nanoparticles for biomedical research and clinical applications
10.1039/d5na00195a · 2025 · External reference
Engineering exosomes as refined biological nanoplatforms for drug delivery
10.1038/aps.2017.12 · 2017 · External reference
The biology of endosomal escape: strategies for enhanced delivery of therapeutics
10.1021/acsnano.5c18112 · 2026 · External reference
Clinical investigation on nebulized human umbilical cord MSC-derived extracellular vesicles for pulmonary fibrosis treatment
10.1038/s41392-025-02262-3 · 2025 · External reference
A comprehensive review of challenges and advances in exosome-based drug delivery systems
10.1039/d4na00501e · 2024 · External reference
Dysregulation of Nrf2 in hepatocellular carcinoma: role in cancer progression and chemoresistance
10.3390/cancers10120481 · 2018 · External reference
Huc-MSCs-derived exosomes attenuate inflammatory pain by regulating microglia pyroptosis and autophagy via the miR-146a-5p/TRAF6 axis
10.1186/s12951-022-01522-6 · 2022 · External reference
Engineering macrophage-derived exosome to deliver pirfenidone: a novel approach to combat silicotic pulmonary fibrosis
2025 · External reference
Extracellular vesicle-based drug overview: research landscape, quality control and nonclinical evaluation strategies
10.1038/s41392-025-02312-w · 2025 · External reference
Optimizing exosome lipid hybrid nanoparticles for enhanced siRNA delivery and improved therapeutic anticancer efficacy in vivo
10.1021/acsnano.5c16991 · 2025 · External reference
Exosomes in cancer nanomedicine: biotechnological advancements and innovations
10.1186/s12943-025-02372-0 · 2025 · External reference
Human umbilical cord mesenchymal stem cell-derived exosomes prevent and alleviate experimental pulmonary fibrosis by modulating the cytoskeleton of macrophages
10.1186/s13287-025-04646-2 · 2025 · External reference
Targeting senescent alveolar epithelial cells using engineered mesenchymal stem cell-derived extracellular vesicles to treat pulmonary fibrosis
10.1021/acsnano.3c10547 · 2024 · External reference
Exosome-based therapeutics for musculoskeletal disorders: advances in engineering, targeting, and biomaterial integration
10.1021/acsnano.5c05416 · 2025 · External reference
Recent advances in modern extracellular vesicle isolation and separation techniques
2026 · External reference
Encapsulation and assessment of therapeutic cargo in engineered exosomes: a systematic review
10.1186/s12951-023-02259-6 · 2024 · External reference
Exosome theranostics: biology and translational medicine
10.7150/thno.21945 · 2018 · External reference
Emerging role of exosomes in cancer therapy: progress and challenges
10.1186/s12943-024-02215-4 · 2025 · External reference
Engineered exosomes in emerging cell-free therapy
10.3389/fonc.2024.1382398 · 2024 · External reference
Engineered exosomes from different sources for cancer-targeted therapy
10.1038/s41392-023-01382-y · 2023 · External reference
MiR-146a-5p engineered hucMSC-derived extracellular vesicles attenuate dermatophagoides farinae-induced allergic airway epithelial cell inflammation
2024 · External reference
MSC-derived exosome ameliorates pulmonary fibrosis by modulating NOD 1/NLRP3-mediated epithelial-mesenchymal transition and inflammation
2025 · External reference
Nrf2 mediates the effects of shionone on silica-induced pulmonary fibrosis
10.1186/s13020-024-00947-5 · 2024 · External reference
SiO2 particles induce pulmonary fibrosis by modulating NLRP3 through the ROS/Keap1/Nrf2 signaling pathway in rats
10.1016/j.fct.2025.115520 · 2025 · External reference
Exosomal let-7i-5p from three-dimensional cultured human umbilical cord mesenchymal stem cells inhibits fibroblast activation in silicosis through targeting TGFBR1
10.1016/j.ecoenv.2022.113302 · 2022 · External reference
Mesenchymal stem cell-exosomal miR-99a attenuate silica-induced lung fibrosis by inhibiting pulmonary fibroblast transdifferentiation
10.3390/ijms252312626 · 2024 · External reference
Cell–cell interactions and communication dynamics in lung fibrosis
10.1016/j.pccm.2024.04.001 · 2024 · External reference
Electroporation-induced siRNA precipitation obscures the efficiency of siRNA loading into extracellular vesicles
10.1016/j.jconrel.2013.08.014 · 2013 · External reference
A scalable platform for EPSC-induced MSC extracellular vesicles with therapeutic potential
10.1186/s13287-025-04507-y · 2025 · External reference
ADSCs-derived exosomes suppress macrophage ferroptosis via the SIRT1/NRF2 signaling axis to alleviate acute lung injury in sepsis
2025 · External reference
Human umbilical cord mesenchymal stem cell-derived extracellular vesicles alleviated silica induced lung inflammation and fibrosis in mice via circPWWP2A/miR-223–3p/NLRP3 axis
10.1016/j.ecoenv.2023.114537 · 2023 · External reference
MiR-146a engineered extracellular vesicles derived from mesenchymal stromal cells more potently attenuate ischaemia–reperfusion injury in lung transplantation
10.1002/ctm2.70298 · 2025 · External reference
Neutrophil membrane-engineered panax ginseng root-derived exosomes loaded miRNA 182-5p targets NOX4/drp-1/NLRP3 signal pathway to alleviate acute lung injury in sepsis: experimental studies
10.1097/js9.0000000000000789 · 2024 · External reference
Lung-penetrating biomimetic extracellular vesicle spherical nucleic acids for pulmonary fibrosis therapy through ROS scavenging and anti-inflammatory effects
2025 · External reference
Melatonin alleviates hyperoxia-induced lung injury through elevating MSC exosomal miR-18a-5p expression to repress PUM2 signaling
10.1096/fj.202400374r · 2024 · External reference
Triptolide-loaded mesenchymal stem cell–derived exosomes ameliorates lipopolysaccharide-induced acute lung injury via induction of nrf-2/HO-1 signaling pathway–dependent autophagy and mitigation of MAPK signaling pathway
2024 · External reference
Nebulized milk exosomes loaded with siTGF-β1 ameliorate pulmonary fibrosis by inhibiting EMT pathway and enhancing collagen permeability
10.1186/s12951-024-02721-z · 2024 · External reference
Engineered exosomes for targeted microRNA delivery to reverse liver fibrosis
10.1016/j.biomaterials.2025.123510 · 2026 · External reference
Engineered exosomes: a promising drug delivery platform with therapeutic potential
10.3389/fmolb.2025.1583992 · 2025 · External reference
Relationship between cumulative silica exposure and silicosis: a systematic review and dose-response meta-analysis
10.1136/thorax-2024-221447 · 2024 · External reference
Microfluidic devices for manufacture of therapeutic extracellular vesicles: advances and opportunities
10.1002/jev2.70132 · 2025 · External reference
Advancements in extracellular vesicles biomanufacturing: a comprehensive overview of large-scale production and clinical research
2025 · External reference
Recent advances in extracellular vesicles for therapeutic cargo delivery
10.1038/s12276-024-01201-6 · 2024 · External reference
Assessment of vault particles in cancer cell line-derived extracellular vesicle preparations
10.1002/jev2.70142 · 2025 · External reference
A critical systematic review of extracellular vesicle clinical trials
10.1002/jev2.12510 · 2024 · External reference
A systematic review and meta-analysis of clinical trials assessing safety and efficacy of human extracellular vesicle-based therapy
10.1002/jev2.12458 · 2024 · External reference
Surface charge engineering shields extracellular vesicles from plasma protein corona to enable systemic extrahepatic targeting
2026 · External reference
Different storage and freezing protocols for extracellular vesicles: a systematic review
10.1186/s13287-024-04005-7 · 2024 · External reference
Enhancing the stabilization potential of lyophilization for extracellular vesicles
10.1002/adhm.202100538 · 2022 · External reference
Rab27a and Rab27b control different steps of the exosome secretion pathway
10.1038/ncb2000 · 2010 · External reference
Direct cytosolic delivery of siRNA via cell membrane fusion using cholesterol-enriched exosomes
10.1038/s41565-024-01785-0 · 2024 · External reference
Designer exosomes produced by implanted cells intracerebrally deliver therapeutic cargo for parkinson's disease treatment
10.1038/s41467-018-03733-8 · 2018 · External reference
A platform for actively loading cargo RNA to elucidate limiting steps in EV-mediated delivery
10.3402/jev.v5.31027 · 2016 · External reference
Engineering hybrid exosomes by membrane fusion with liposomes
2016 · External reference
Modification of extracellular vesicles by fusion with liposomes for the design of personalized biogenic drug delivery systems
10.1021/acsnano.8b02053 · 2018 · External reference
Exosome–liposome hybrid nanoparticles deliver CRISPR/Cas9 system in MSCs
10.1002/advs.201700611 · 2018 · External reference
Multi-omics study of silicosis reveals the potential therapeutic targets PGD2 and TXA2
10.7150/thno.47627 · 2021 · External reference
Applications of matrix metalloproteinase-9-related nanomedicines in tumors and vascular diseases
10.3390/pharmaceutics17040479 · 2025 · External reference
Unlocking pH-responsive dual payload release through hydrazone linkage chemistry
10.1016/j.bmc.2025.118172 · 2025 · External reference
Design of pH-responsive nanomaterials based on the tumor microenvironment
10.2147/ijn.s504629 · 2025 · External reference
Harnessing endogenous stimuli for responsive materials in theranostics
10.1021/acsnano.0c09115 · 2021 · External reference
Delivery strategies to improve the pharmacological efficacy of NRF2 modulators: a review
10.1039/d5md00571j · 2025 · External reference
Advancing polyphenol-based nanomedicine for inflammatory bowel disease: challenges and opportunities
10.2147/jir.s487942 · 2024 · External reference
Advances in Nrf2 signaling pathway by targeted nanostructured-based drug delivery systems
10.3390/biomedicines12020403 · 2024 · External reference
