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References from Dual-target chemical profiling of anti-influenza multi-components from Isatidis Radix via direct binding to neuraminidase and hemagglutinin. Local targets link to admitted publications; unresolved targets remain external evidence.
Isatidis Radix and Isatidis folium: a systematic review on ethnopharmacology, phytochemistry and pharmacology
10.1016/j.jep.2021.114648 · 2022 · External reference
The dirigent multigene family in Isatis indigotica: gene discovery and differential transcript abundance
10.1186/1471-2164-15-388 · 2014 · External reference
Radix Isatidis polysaccharides inhibit influenza a virus and influenza a virus-induced inflammation via suppression of host TLR3 signaling in vitro
10.3390/molecules22010116 · 2017 · External reference
Lariciresinol: a potent natural compound with diverse therapeutic and health benefits
10.1080/14786419.2025.2611424 · 2026 · External reference
Anti-tumor alkaloids from Peganum harmala
10.1016/j.phytochem.2022.113107 · 2022 · External reference
A systemic review for ethnopharmacological studies on fortune: bioactive compounds and their therapeutic insights
10.1142/s0192415x22500069 · 2022 · External reference
Analysis of research status and industrialization prospect of Isatidis Radix based on bibliometrics and patents
2024 · External reference
Antiviral activities against influenza virus (FM1) of bioactive fractions and representative compounds extracted from Banlangen (Radix Isatidis)
10.1016/s0254-6272(16)30051-6 · 2016 · External reference
Antiviral activity of Isatidis Radix derived glucosinolate isomers and their breakdown products against influenza a in vitro/ovo and mechanism of action
10.1016/j.jep.2020.112550 · 2020 · External reference
Discovery and molecular elucidation of the anti-influenza material basis of Banlangen granules based on biological activities and ultra-high performance liquid chromatography coupled with quadrupole-orbitrap mass spectrometry
10.1016/j.jep.2022.115683 · 2022 · External reference
The evolution and future of influenza pandemic preparedness
10.1038/s12276-021-00603-0 · 2021 · External reference
Novel influenza D virus: epidemiology, pathology, evolution and biological characteristics
10.1080/21505594.2017.1365216 · 2017 · External reference
Influenza neuraminidase inhibitors: antiviral action and mechanisms of resistance
10.1111/irv.12047 · 2013 · External reference
Oseltamivir: a review of its use in influenza
10.2165/00003495-200161020-00011 · 2001 · External reference
Development of antiviral drugs for influenza
10.2169/internalmedicine.5157-24 · 2026 · External reference
Biological evaluation of Radix Isatidis based on neuraminidase activity assay
2009 · External reference
Establishment of a quality grading standard of Isatidis Radix decoction pieces based on appearance traits and internal quality indexes
2024 · External reference
Development of a thin-layer chromatography bioautographic assay for neuraminidase inhibitors hyphenated with electrostatic field induced spray ionisation-mass spectrometry for identification of active Isatis indigotica root compounds
10.1016/j.chroma.2020.461597 · 2021 · External reference
Influenza A: understanding the viral life cycle
2009 · External reference
Influenza A virus cell entry, replication, virion assembly and movement
10.3389/fimmu.2018.01581 · 2018 · External reference
Influenza hemagglutinin and neuraminidase membrane glycoproteins
10.1074/jbc.r110.129809 · 2010 · External reference
The indole alkaloids from the roots of Isatidis Radix
10.1016/j.fitote.2021.104950 · 2021 · External reference
Inhibits influenza A virus (H1N1) virulent protein production and autophagosome accumulation
2024 · External reference
Chemoreactive-inspired discovery of influenza a virus dual inhibitor to block hemagglutinin-mediated adsorption and membrane fusion
10.1021/acs.jmedchem.0c00312 · 2020 · External reference
Novel benzamide derivatives with indole moiety as dual-target antiviral agents: rational design, efficient synthesis, and potent anti-influenza activity through concurrent binding to PAC terminal domain and viral nucleoprotein
10.1016/j.ejmech.2025.117681 · 2025 · External reference
Aspversols A-H, monomeric and dimeric phenolic bisabolane sesquiterpenoids with antiviral and cytotoxic activities from polar moss-derived fungus Aspergillus sp. CPCC 401664
10.1016/j.phytochem.2025.114515 · 2025 · External reference
In vivo effect of quantified flavonoids-enriched extract of Scutellaria baicalensis root on acute lung injury induced by influenza a virus
10.1016/j.phymed.2018.12.009 · 2019 · External reference
Comparative analysis of the chemical composition and cytotoxic activity of broccoli by-products as an alternative source of bioactive compounds
2025 · External reference
Two new alkaloids isolated from tetraploidy Banlangen
2000 · External reference
Alkaloids from the root of Isatis indigotica
10.1021/np3002833 · 2012 · External reference
Antiviral glycosidic bisindole alkaloids from the roots of Isatis indigotica
10.1080/10286020.2015.1055729 · 2015 · External reference
Four pairs of alkaloid enantiomers from Isatis indigotica Fortune Ex Lindl. with neuroprotective effects against H2O2-induced SH-SY5Y cell injury
10.1016/j.bioorg.2020.103650 · 2020 · External reference
Structure elucidation and synthesis of (2S)-4-oxo-1-azabicyclo[3.3.0]octa-5,7-diene-2-carboxylic acid, a new metabolite isolated from Streptomyces olivaceus
10.1016/s0040-4039(01)81888-8 · 1981 · External reference
Aromatic compounds from endophytic fungus Colletotrichum sp. L10 of Cephalotaxus hainanensis Li
10.1016/j.fitote.2012.02.012 · 2012 · External reference
The behavior of inososes in neutral and basic aqueous solution
10.1016/0008-6215(79)80012-9 · 1979 · External reference
Unresolved reference
1978 · External reference
Isatis indigotica: from (ethno) botany, biochemistry to synthetic biology
2021 · External reference
Alkaloids in Isatis indigotica and their chemotaxonomic significance
10.1016/j.bse.2024.104800 · 2024 · External reference
Anti-influenza activity of betulinic acid from Zizyphus jujuba on influenza a/PR/8 virus
10.4062/biomolther.2015.019 · 2015 · External reference
Isatis indigotica: a review of phytochemistry, pharmacological activities and clinical applications
10.1093/jpp/rgab014 · 2021 · External reference
Indole alkaloid sulfonic acids from an aqueous extract of Isatis indigotica roots and their antiviral activity
10.1016/j.apsb.2017.04.003 · 2017 · External reference
Sulfur-enriched alkaloids from the root of Isatis indigotica
10.1016/j.apsb.2018.08.005 · 2018 · External reference
Antiviral activity of Isatis indigotica root-derived clemastanin B against human and avian influenza a and B viruses in vitro
10.3892/ijmm.2013.1274 · 2013 · External reference
Lariciresinol-4-O-β-d-glucopyranoside from the root of Isatis indigotica inhibits influenza a virus-induced pro-inflammatory response
10.1016/j.jep.2015.08.037 · 2015 · External reference
Phenolic compounds from Limonium densiflorum: a multifaceted approach to antioxidant, anti-inflammatory, anticancer, and anti-influenza activities
10.1080/09603123.2024.2342572 · 2025 · External reference
(+)-Pinoresinol-O-β-d-glucopyranoside from Eucommia ulmoides Oliver and its anti-inflammatory and antiviral effects against influenza a (H1N1) virus infection
2019 · External reference
In vitro anti-influenza virus activities of a new lignan glycoside from the latex of Calotropis gigantea
10.1371/journal.pone.0104544 · 2014 · External reference
The genus Isatis L.: a review on its flavonoid and phenolic compound profile
10.25135/rfac.12.2207.2505 · 2022 · External reference
In vitro antiviral activity of catechins and their analogs against H1N1 and their structure-activity relationship
2023 · External reference
Chemical constituents from root of Isatis indigotica
2013 · External reference
Research progress on the determination methods of main chemical components in Radix Isatidis
2020 · External reference
Research progress of antiviral active ingredients of Isatidis Radix
2016 · External reference
Study progress on antiviral activities and mechanisms of flavonoids in traditional Chinese medicine and natural medicines
2018 · External reference
A study on catalytic and non-catalytic sites of H5N1 and H1N1 neuraminidase as the target for chalcone inhibitors
10.1186/s13765-021-00639-w · 2021 · External reference
Inhibition of influenza hemagglutinin with the antiviral inhibitor arbidol using a proteomics based approach and mass spectrometry
10.1016/j.antiviral.2013.08.021 · 2013 · External reference
Construction of information bank of chemical components in Isatidis Radix
2022 · External reference