Research graph
References from Design and synthesis of new 2-aminopyrimidine-thiazolidinone hybrids with enhanced antimicrobial activity: in-vitro evaluation and multiscale computational studies. Local targets link to admitted publications; unresolved targets remain external evidence.
Recent insights into synthesis, biological activities, structure activity relationship and molecular interactions of thiazolidinone hybrids: a systematic review
10.1080/00397911.2023.2269582 · 2024 · External reference
Heterocycle compounds with antimicrobial activity
10.2174/1381612826666200206093815 · 2020 · External reference
Design, synthesis, spectroscopic characterization of new pyrazole carbothioamides as antifungal and antibacterial candidates
2021 · External reference
Synthesis and antimicrobial activity of thiophene-based heterocycles derived from thiophene-2-carbohydrazide
10.4155/fmc-2023-0304 · 2024 · External reference
Synthetic and medicinal perspective of thiazolidinones: a review
10.1016/j.bioorg.2017.10.014 · 2017 · External reference
Synthesis and in silico evaluation of thiazole, thiazolidinone, and pyrimidinethione candidates bearing a benzo [h] quinoline scaffold as potential antiproliferative agents
10.1080/10406638.2025.2552424 · 2026 · External reference
Straightforward synthesis and in silico evaluation of pyrazolylthiazolidinone derivatives as prospective antiproliferative agents
10.1016/j.bioorg.2025.109036 · 2025 · External reference
Novel 4-thiazolidinone derivatives as anti-infective agents: synthesis, characterization, and antimicrobial evaluation
10.1155/2016/8086762 · 2016 · External reference
Design, synthesis and in vitro antimicrobial activity of furan-based pyrimidine-thiazolidinones as potential bioactive molecules
2023 · External reference
Identification of CH2-linked quinolone-aminopyrimidine hybrids as potent anti-MRSA agents: low resistance potential and lack of cross-resistance with fluoroquinolone antibiotics
10.1016/j.ejmech.2024.116399 · 2024 · External reference
Antibacterial activity and DNA gyrase inhibitory potency of some novel pyrazolo [1, 5-a] pyrimidine-based thiazolidin-4-one hybrids linked to aryl units
10.1080/00397911.2026.2634260 · 2026 · External reference
Synthesis, characterization, DFT, antibacterial, ADME-T properties, and molecular docking of new N-functionalized thiazolidinones
10.1016/j.molstruc.2024.138004 · 2024 · External reference
Synthesis and antibiofilm evaluation of N-acyl-2-aminopyrimidine derivatives against Acinetobacter baumannii
10.1016/j.bmc.2022.117095 · 2022 · External reference
Design, synthesis, molecular dynamic simulation studies, and antibacterial evaluation of new spirocyclic aminopyrimidines
10.1016/j.molstruc.2023.134912 · 2023 · External reference
Folate biosynthesis pathway: mechanisms and insights into drug design for infectious diseases
10.4155/fmc-2017-0168 · 2018 · External reference
Dihydrofolate reductase inhibitors as antibacterial agents
10.1016/j.bcp.2005.10.052 · 2006 · External reference
Trimethoprim and other nonclassical antifolates an excellent template for searching modifications of dihydrofolate reductase enzyme inhibitors
10.1038/s41429-019-0240-6 · 2020 · External reference
Inhibitory properties and X-ray crystallographic study of the binding of AR-101, AR-102 and iclaprim in ternary complexes with NADPH and dihydrofolate reductase from Staphylococcus aureus
10.1107/s0907444909013936 · 2009 · External reference
Propargyl-linked antifolates are dual inhibitors of Candida albicans and Candida glabrata
10.1021/jm401916j · 2014 · External reference
Unveiling the antimicrobial activity of some new Quinazolindione-anchored pyrazole, chromene and/or furo [2, 3-b] indole hybrids through acylthiourea conjugate: synthesis, molecular docking, Semiempirical calculations and ADMET prediction
10.1016/j.rechem.2025.102175 · 2025 · External reference
Hybrids of thiazolidinone with 1, 2, 3-triazole derivatives: design, synthesis, biological evaluation, in silico studies, molecular docking, molecular dynamics simulations, and ADMET profiling
10.1080/07391102.2022.2164357 · 2023 · External reference
Thiazolidin-4-ones as potential antimicrobial agents: experimental and in silico evaluation
10.3390/molecules27061930 · 2022 · External reference
Design, synthesis, and biological evaluation of novel thiazolidinone-containing quinoxaline-1, 4-di-N-oxides as antimycobacterial and antifungal agents
2020 · External reference
4-Thiazolidinone derivatives as potent antimicrobial agents: microwave-assisted synthesis, biological evaluation and docking studies
10.1039/c4md00399c · 2015 · External reference
N-terminally modified linear and branched spermine backbone dipeptidomimetics against planktonic and sessile methicillin-resistant Staphylococcus aureus
10.1128/aac.03391-14 · 2014 · External reference
Design, synthesis and molecular modelling of novel 4-thiazolidinones of potential activity against gram positive bacteria
10.1007/s00044-012-0115-x · 2013 · External reference
Synthesis and evaluation of antibacterial and antifungal activities of 4-thiazolidinones and 2-azetidinones derivatives from chalcone
10.1007/s00044-017-1837-6 · 2017 · External reference
Synthesis, characterization and biological evaluation of thioureas, acylthioureas and 4-thiazolidinones as anticancer and antiviral agents
2017 · External reference
Synthesis, in-vitro and in-silico study of novel thiazoles as potent antibacterial agents and MurB inhibitors
10.1002/ardp.201900309 · 2020 · External reference
Design, synthesis and biological evaluation of new substituted 5-benzylideno-2-adamantylthiazol [3, 2-b][1, 2, 4] triazol-6 (5H) ones. Pharmacophore models for antifungal activity
2016 · External reference
Computational analysis of novel 4-thiazolidinone derivatives as potential anti-breast cancer agents: docking, pharmacokinetics, and molecular dynamics study
2024 · External reference
Identification of catechin as main protease inhibitor of SARS-CoV-2 omicron variant using molecular docking, molecular dynamics, PCA, DCCM, MM/GBSA and ADMET profiling
10.1080/14786419.2024.2421907 · 2026 · External reference
Molecular dynamics simulation, free energy landscape and binding free energy computations in exploration the anti-invasive activity of amygdalin against metastasis
10.1016/j.cmpb.2020.105660 · 2020 · External reference