Research graph
References from Pinnatifolin from Syringa pinnatifolia protects against myocardial ischemic injury in mice by targeting GPX4 to suppress ferroptosis. Local targets link to admitted publications; unresolved targets remain external evidence.
Phytochemical and chemotaxonomic study of Syringa pinnatifolia Hemsl.(Oleaceae)
10.1016/j.bse.2018.09.006 · 2018 · External reference
Unresolved reference
1998 · External reference
Unresolved reference
1987 · External reference
Chemical and pharmacological research progress on Mongolian folk medicine Syringa pinnatifolia
2025 · External reference
Anti-myocardial ischemia effect of Syringa pinnatifolia Hemsl. By inhibiting expression of cyclooxygenase-1 and -2 in myocardial tissues of mice
10.1016/j.jep.2016.04.039 · 2016 · External reference
Syringa pinnatifolia Hemsl. Fraction protects against myocardial ischemic injury by targeting the p53-mediated apoptosis pathway
10.1016/j.phymed.2018.09.188 · 2019 · External reference
Pharmacological evaluation of Mongolian medicine Syringa pinnatifolia fraction I against acute myocardial ischemia in mice
2019 · External reference
Equivalent evaluation and biological ingredients of Syringa pinnatifolia against acute myocardial ischemia in mice
10.1016/j.jep.2023.116904 · 2024 · External reference
Syringa pinnatifolia lignans contribute to the cardioprotective effect against ischemic injury through the Nrf2/HO-1 signaling pathway in vitro and in vivo
10.1002/cbdv.202502483 · 2025 · External reference
Ferroptosis in heart failure
10.1016/j.yjmcc.2022.10.004 · 2022 · External reference
Broadening horizons: the role of ferroptosis in cancer
10.1038/s41571-020-00462-0 · 2021 · External reference
ACSL4 dictates ferroptosis sensitivity by shaping cellular lipid composition
10.1038/nchembio.2239 · 2017 · External reference
Protosappanin a protects DOX-induced myocardial injury and cardiac dysfunction by targeting ACSL4/FTH1 axis-dependent ferroptosis
10.1002/advs.202310227 · 2024 · External reference
Quantitative proteomic analyses reveal that GPX4 downregulation during myocardial infarction contributes to ferroptosis in cardiomyocytes
10.1038/s41419-019-2061-8 · 2019 · External reference
Ferroptosis: a regulated cell death nexus linking metabolism, redox biology, and disease
10.1016/j.cell.2017.09.021 · 2017 · External reference
The cell biology of ferroptosis
10.1038/s41580-024-00703-5 · 2024 · External reference
A cold-inducible coactivator of nuclear receptors linked to adaptive thermogenesis
10.1016/s0092-8674(00)81410-5 · 1998 · External reference
Mitochondrial dynamics reveal potential to facilitate axonal regeneration after spinal cord injury
10.1186/s12967-025-06611-2 · 2025 · External reference
New curcumin derivative induces ferroptosis in MCF-7 cells through activating SLC7A11/GPX4 axis
10.1016/j.bmc.2025.118078 · 2025 · External reference
Sesquiterpenoids and lignans from the roots of Syringa pinnatifolia
10.1248/cpb.c14-00320 · 2014 · External reference
9,9′-epoxylignans from Syringa pinnatifolia: a typical case of stereochemical assignment by a quantum chemical calculation with MAEΔΔδ parameter
10.1016/j.phytochem.2024.113978 · 2024 · External reference
Construction of an equal mass for equivalent effect transmission strategy based on the analgesic substance research of Syringa pinnatifolia
2026 · External reference
Synergy and antagonism in natural product extracts: when 1 + 1 does not equal 2
10.1039/c9np00011a · 2019 · External reference
The power of lignans: plant compounds with multifaceted health-promoting effects
10.3390/metabo15090589 · 2025 · External reference
The multifaceted regulation of mitochondria in ferroptosis
10.3390/life11030222 · 2021 · External reference
Cardioprotective effects of the jiming formula on myocardial metabolism in mice with myocardial infarction via the AMPK/SIRT1/PGC-1α pathway
10.1016/j.phymed.2025.156727 · 2025 · External reference
Lipid peroxidation and ferroptosis: the role of GSH and GPx4
10.1016/j.freeradbiomed.2020.02.027 · 2020 · External reference
Research progress on GPX4 targeted compounds
10.1016/j.ejmech.2024.116548 · 2024 · External reference