Research graph
References from Research progress on plant-derived exosome-like nanovesicles in regulating and promoting tissue repair. Local targets link to admitted publications; unresolved targets remain external evidence.
Bio-Inspired lipid nanovesicles (iNVs) incorporating membrane proteins from healthy tendon stem cells for targeted protein restoration in tendinopathic in vitro model
10.1080/21691401.2025.2599071 · 2026 · External reference
Lithium chloride-treated human umbilical cord mesenchymal stem cells-derived exsomes promote hair growth by regulating miR-146a-5p-wnt pathway
10.1093/stcltm/szaf049 · 2025 · External reference
Mechanisms and therapeutic potential of stem cell-derived extracellular vesicles as nanocarriers in musculoskeletal disorders
10.1002/biot.70172 · 2026 · External reference
The emerging role of plant-derived exosomes-like nanoparticles in immune regulation and periodontitis treatment
2022 · External reference
Advances in plant-derived vesicle like nanoparticles-based therapies for inflammatory diseases
2025 · External reference
Research status and challenges of plant-derived exosome-like nanoparticles
10.1016/j.biopha.2024.116543 · 2024 · External reference
The dual role of extracellular vesicles derived from animal and human immune cells: A systematic review
10.5455/javar.2025.l915 · 2025 · External reference
Extracellular vesicle-integrated core-shell nanofibers synergize multi-target healing mechanisms for accelerated repair of large-volume skin defects
2026 · External reference
3D hESC exosomes enriched with miR-6766-3p ameliorates liver fibrosis by attenuating activated stellate cells through targeting the TGFbetaRII-SMADS pathway
10.1186/s12951-021-01138-2 · 2021 · External reference
miR-19b-3p engineered adipose-derived stem cell exosomes attenuate acute liver failure via promoting tissue repair and microenvironment remodeling
2026 · External reference
Salidroside-loaded stem cell-derived artificial nanovesicles in hydrogel microneedles alleviate inflammation and enhance diabetic wound regeneration
2026 · External reference
Plant-derived exosomes: Unveiling the similarities and disparities between conventional extract and innovative form
10.1016/j.phymed.2025.157087 · 2025 · External reference
Plant-derived exosomes in therapeutic nanomedicine, paving the path toward precision medicine
10.1016/j.phymed.2024.156087 · 2024 · External reference
Natural Nanoparticles for Drug Delivery: Proteomic Insights and Anticancer Potential of Doxorubicin-Loaded Avocado Exosomes
2025 · External reference
Purposing plant-derived exosomes-like nanovesicles for drug delivery: patents and literature review
10.1080/13543776.2023.2195093 · 2023 · External reference
Aloe vera-derived extracellular vesicle-like particles suppress pancreatic carcinoma progression through triggering pyroptosis via ROS-GSDMD/E signaling pathway
10.1186/s13020-025-01153-7 · 2025 · External reference
Ginger-Derived Exosome-Like Nanoparticles: The Effect of Extraction Methods on Metabolites and in vitro Anti-Lung Cancer Activity
10.2147/ijn.s541948 · 2025 · External reference
Olea europaea leaf exosome-like nanovesicles encapsulated in a hyaluronic acid / tannic acid hydrogel dressing with dual "defense-repair" effects for treating skin photoaging
2024 · External reference
Garlic-Derived Exosome-like Nanovesicles-Based Wound Dressing for Staphylococcus aureus Infection Visualization and Treatment
10.1021/acsabm.3c01256 · 2024 · External reference
Pueraria lobata-derived exosome-like nanovesicles alleviate osteoporosis by enhacning autophagy
10.1016/j.jconrel.2023.11.020 · 2023 · External reference
Oral administration of cranberry-derived exosomes attenuates murine premature ovarian failure in association with changes in the specific gut microbiota and diminution in ovarian granulosa cell PANoptosis
10.1039/d4fo03468f · 2024 · External reference
Novel plant-derived exosome-like nanovesicles from Catharanthus roseus: preparation, characterization, and immunostimulatory effect via TNF-alpha/NF-kappaB/PU.1 axis
10.1186/s12951-023-01919-x · 2023 · External reference
The potential of plant-derived exosome-like nanovesicles from Centella asiatica leaves (CA-PDENs) for anti-inflammation and prevention of UVB-induced photoaging
10.1080/20565623.2026.2654777 · 2026 · External reference
Perilla frutescens Leaf-Derived Extracellular Vesicle-Like Particles Carry Pab-miR-396a-5p to Alleviate Psoriasis by Modulating IL-17 Signaling
2025 · External reference
Plant-based Exosome Injections for Skin Wound Healing: Experimental Study
2025 · External reference
Topical Application of Centella asiatica in Wound Healing: Recent Insights into Mechanisms and Clinical Efficacy
10.3390/pharmaceutics16101252 · 2024 · External reference
Garlic-Derived Exosome-Like Nanovesicles: A Promising Natural Nanotherapy for Periodontitis via PHGDH/PI3K/AKT-Mediated Metabolic and Inflammatory Regulation
10.2147/ijn.s510417 · 2025 · External reference
Garlic-derived exosome-like nanovesicle core-shell platform for sequential infection treatment and tissue repair
10.1186/s12951-026-04227-2 · 2026 · External reference
Asiaticoside alleviated NAFLD by activating Nrf2 and inhibiting the NF-kappaB pathway
10.1016/j.phymed.2024.156317 · 2025 · External reference
Biosynthesis and bioactivities of triterpenoids from Centella asiatica: Challenges and opportunities
10.1016/j.biotechadv.2025.108541 · 2025 · External reference
Lemon-derived nanovesicles achieve antioxidant and anti-inflammatory effects activating the AhR/Nrf2 signaling pathway
10.1016/j.isci.2023.107041 · 2023 · External reference
Lemon-derived nanoparticle-functionalized hydrogels regulate macrophage reprogramming to promote diabetic wound healing
10.1186/s12951-025-03138-y · 2025 · External reference
A pH-responsive hydrogel based on polysaccharides incorporated with honeysuckle-derived exosome-like nanovesicles for the management of infected wound
10.1016/j.ijbiomac.2026.152976 · 2026 · External reference
Aloe vera peel-derived nanovesicles display anti-inflammatory properties and prevent myofibroblast differentiation
10.1016/j.phymed.2023.155108 · 2024 · External reference
Morinda Officinalis-Derived Extracellular Vesicle-like Particles Promote Wound Healing via Angiogenesis
10.1021/acsami.5c01640 · 2025 · External reference
Exosome-like nanoparticles derived from Salvia miltiorrhiza promote diabetic wound healing by reducing oxidative stress and inflammation
10.1016/j.bbrc.2026.154115 · 2026 · External reference
Activating the cellular scavenger: A bioactive hydrogel promotes diabetic wounds via plant exosome-like nanovesicles enhanced macrophage efferocytosis
2026 · External reference
Ginseng-derived nanoparticles accelerate diabetic wound healing by modulating macrophage polarization and restoring endothelial cell function
2025 · External reference
EGF-loaded, bioactive-rich Panax notoginseng-derived nanovesicles accelerate skin wound healing
10.3389/fcell.2026.1737435 · 2026 · External reference
Restoration of tendon repair microenvironment by grapefruit exosome-loaded microneedle system for tendinopathy therapy
2025 · External reference
Microenvironment-responsive collagen hydrogel with Houttuynia cordata Thunb vesicles for diabetic wound repair
2025 · External reference
Adaptive ROS-Responsive Dual-Layered Hydrogel with Ginkgo biloba-Derived Exosome-Like Nanovesicles for Diabetic Wound Healing
10.1002/adhm.202505954 · 2026 · External reference
Plant-derived nanovesicles from Ginkgo biloba seeds mitigate LPS-induced endothelial dysfunction and promote vascular homeostasis
2025 · External reference
Current progress of plant-derived exosome-like nanovesicles on the regulation of osteoporosis and osteoarthritis
10.1080/07853890.2025.2549524 · 2025 · External reference
Epimedium brevicornu Maxim.-derived extracellular vesicle-like particles stimulate VEGF-mediated angiogenesis to alleviate postmenopausal osteoporosis
10.1016/j.phymed.2025.157259 · 2025 · External reference
Gouqi-derived Nanovesicles (GqDNVs) promoted MC3T3-E1 cells proliferation and improve fracture healing
10.1016/j.phymed.2025.156755 · 2025 · External reference
Morinda Officinalis-derived extracellular vesicle-like particles: Anti-osteoporosis effect by regulating MAPK signaling pathway
10.1016/j.phymed.2024.155628 · 2024 · External reference
Therapeutic potential of Panax ginseng-derived nanovesicles in osteoporosis through enhanced osteoblast
10.1016/j.jgr.2026.101016 · 2026 · External reference
Garlic-derived Exosomes Alleviate Osteoarthritis Through Inhibiting the MAPK Signaling Pathway
10.1007/s12010-024-05047-6 · 2025 · External reference
Nanogel Loaded with Perilla frutescens Leaf-Derived Exosome-like Nanovesicles and Indomethacin for the Treatment of Inflammatory Arthritis
2025 · External reference
Lotus-derived protein-rich nanoparticles relieve inflammatory bowel disease by modulating gut microbiota and bile acid metabolism
10.1016/j.ijbiomac.2026.152946 · 2026 · External reference
Natural Broccoli Sprout-Derived Exosomes Encapsulating Bioactive Molecules as a Novel Nanomedicine for Repair of Intestinal Inflammation
10.1208/s12248-026-01241-y · 2026 · External reference
Garlic-derived exosome-like nanovesicles alleviate dextran sulphate sodium-induced mouse colitis via the TLR4/MyD88/NF-kappaB pathway and gut microbiota modulation
10.1039/d3fo01094e · 2023 · External reference
MicroRNA-Enriched Plant-Derived Exosomes Alleviate Colitis by Modulating Systemic Immunity, Metabolic Homeostasis, and Gut Microbiota
2025 · External reference
Blueberry-derived exosome like nanovesicles carry RNA cargo into HIEC-6 cells and down-regulate LPS-induced inflammatory gene expression: A proof-of-concept study
10.1016/j.abb.2024.110266 · 2025 · External reference
Chinese bayberry exosome-like nanoparticles attenuate DSS-induced colitis via immunomodulation, barrier restoration, and microbiota remodeling
2026 · External reference
Edible Pueraria lobata-Derived Exosomes Promote M2 Macrophage Polarization
10.3390/molecules27238184 · 2022 · External reference
Edible pueraria lobata-derived exosome-like nanovesicles ameliorate dextran sulfate sodium-induced colitis associated lung inflammation through modulating macrophage polarization
10.1016/j.biopha.2023.116098 · 2024 · External reference
Ginger-derived vesicle-like nanoparticles loaded with curcumin to alleviate ionizing radiation-induced intestinal damage via gut microbiota regulation
10.1080/19490976.2025.2531210 · 2025 · External reference
Plum-derived exosome-like nanovesicles alleviate DSS-induced colitis through gut and liver protection
10.1039/d5fo04597e · 2026 · External reference
Blueberry-derived exosomes-like nanoparticles ameliorate nonalcoholic fatty liver disease by attenuating mitochondrial oxidative stress
10.1038/s41401-021-00681-w · 2022 · External reference
Endothelial-targeted modification of ginseng-derived exosomes for IL-6 SiRNA delivery ameliorates hepatic ischemia-reperfusion injury
10.1186/s12951-025-03954-2 · 2026 · External reference
Turmeric-derived exosome-coated ZIF-8 nanoplatform for targeted delivery of TGF-beta1 siRNA in the treatment of liver fibrosis
10.1186/s12951-026-04430-1 · 2026 · External reference
Garlic-derived exosome-like nanovesicles as a hepatoprotective agent alleviating acute liver failure by inhibiting CCR2/CCR5 signaling and inflammation
10.1016/j.bioadv.2023.213592 · 2023 · External reference
Neuroprotective effect of lemon-derived exosome-like nanovesicles on transient global cerebral ischemia/reperfusion injury in rat
10.1007/s12010-026-05605-0 · 2026 · External reference
Houttuynia cordata Thunb-derived extracellular vesicle-like particles alleviate ischemic brain injury by miR159a targeting ACSL4 to suppress ferroptosis
10.1186/s13020-025-01193-z · 2025 · External reference
Plant-derived exosomes extracted from Lycium barbarum L. loaded with isoliquiritigenin to promote spinal cord injury repair based on 3D printed bionic scaffold
10.1002/btm2.10646 · 2024 · External reference
Neuroprotective Effects of Salvia Miltiorrhiza-Derived Extracellular Nanovesicles in Traumatic Brain Injury
10.1177/08977151251383549 · 2026 · External reference
A natural derivative from exosome of Inula japonica Thunb.: Preventing acute lung injury through the gut microbiota-metabolites axis
10.1016/j.colsurfb.2026.115654 · 2026 · External reference
Houttuynia cordata-derived exosome-like nanovesicles attenuate acute lung injury with concomitant changes in CXCL10 and p38 MAPK/ATF2 signaling
10.1016/j.bioadv.2026.214901 · 2026 · External reference
Ginger exosome-like nanoparticle-derived miRNA therapeutics: A strategic inhibitor of intestinal inflammation
10.1016/j.jare.2024.04.001 · 2025 · External reference
Whitening and anti-inflammatory activities of exosomes derived from leuconostoc mesenteroides subsp. db-21 strain isolated from camellia japonica flower
10.3390/molecules30051124 · 2025 · External reference
Light modulates plant-derived extracellular vesicle properties: a photosensitive-responsive nanodelivery system
10.1186/s11671-025-04266-y · 2025 · External reference
Adaptive ROS-Responsive Dual-Layered Hydrogel with Ginkgo biloba-Derived Exosome-Like Nanovesicles for Diabetic Wound Healing
10.1002/adhm.202505954 · ExternalCitation · doi-reference
Mechanisms and therapeutic potential of stem cell-derived extracellular vesicles as nanocarriers in musculoskeletal disorders
10.1002/biot.70172 · ExternalCitation · doi-reference
Plant-derived exosomes extracted from Lycium barbarum L. loaded with isoliquiritigenin to promote spinal cord injury repair based on 3D printed bionic scaffold
10.1002/btm2.10646 · ExternalCitation · doi-reference
Garlic-derived Exosomes Alleviate Osteoarthritis Through Inhibiting the MAPK Signaling Pathway
10.1007/s12010-024-05047-6 · ExternalCitation · doi-reference
Neuroprotective effect of lemon-derived exosome-like nanovesicles on transient global cerebral ischemia/reperfusion injury in rat
10.1007/s12010-026-05605-0 · ExternalCitation · doi-reference
Blueberry-derived exosome like nanovesicles carry RNA cargo into HIEC-6 cells and down-regulate LPS-induced inflammatory gene expression: A proof-of-concept study
10.1016/j.abb.2024.110266 · ExternalCitation · doi-reference
Exosome-like nanoparticles derived from Salvia miltiorrhiza promote diabetic wound healing by reducing oxidative stress and inflammation
10.1016/j.bbrc.2026.154115 · ExternalCitation · doi-reference
Garlic-derived exosome-like nanovesicles as a hepatoprotective agent alleviating acute liver failure by inhibiting CCR2/CCR5 signaling and inflammation
10.1016/j.bioadv.2023.213592 · ExternalCitation · doi-reference
Houttuynia cordata-derived exosome-like nanovesicles attenuate acute lung injury with concomitant changes in CXCL10 and p38 MAPK/ATF2 signaling
10.1016/j.bioadv.2026.214901 · ExternalCitation · doi-reference
Edible pueraria lobata-derived exosome-like nanovesicles ameliorate dextran sulfate sodium-induced colitis associated lung inflammation through modulating macrophage polarization
10.1016/j.biopha.2023.116098 · ExternalCitation · doi-reference
Research status and challenges of plant-derived exosome-like nanoparticles
10.1016/j.biopha.2024.116543 · ExternalCitation · doi-reference
Biosynthesis and bioactivities of triterpenoids from Centella asiatica: Challenges and opportunities
10.1016/j.biotechadv.2025.108541 · ExternalCitation · doi-reference
A natural derivative from exosome of Inula japonica Thunb.: Preventing acute lung injury through the gut microbiota-metabolites axis
10.1016/j.colsurfb.2026.115654 · ExternalCitation · doi-reference
Lotus-derived protein-rich nanoparticles relieve inflammatory bowel disease by modulating gut microbiota and bile acid metabolism
10.1016/j.ijbiomac.2026.152946 · ExternalCitation · doi-reference
A pH-responsive hydrogel based on polysaccharides incorporated with honeysuckle-derived exosome-like nanovesicles for the management of infected wound
10.1016/j.ijbiomac.2026.152976 · ExternalCitation · doi-reference
Lemon-derived nanovesicles achieve antioxidant and anti-inflammatory effects activating the AhR/Nrf2 signaling pathway
10.1016/j.isci.2023.107041 · ExternalCitation · doi-reference
Ginger exosome-like nanoparticle-derived miRNA therapeutics: A strategic inhibitor of intestinal inflammation
10.1016/j.jare.2024.04.001 · ExternalCitation · doi-reference
Pueraria lobata-derived exosome-like nanovesicles alleviate osteoporosis by enhacning autophagy
10.1016/j.jconrel.2023.11.020 · ExternalCitation · doi-reference
Therapeutic potential of Panax ginseng-derived nanovesicles in osteoporosis through enhanced osteoblast
10.1016/j.jgr.2026.101016 · ExternalCitation · doi-reference
Aloe vera peel-derived nanovesicles display anti-inflammatory properties and prevent myofibroblast differentiation
10.1016/j.phymed.2023.155108 · ExternalCitation · doi-reference
Morinda Officinalis-derived extracellular vesicle-like particles: Anti-osteoporosis effect by regulating MAPK signaling pathway
10.1016/j.phymed.2024.155628 · ExternalCitation · doi-reference
Plant-derived exosomes in therapeutic nanomedicine, paving the path toward precision medicine
10.1016/j.phymed.2024.156087 · ExternalCitation · doi-reference
Asiaticoside alleviated NAFLD by activating Nrf2 and inhibiting the NF-kappaB pathway
10.1016/j.phymed.2024.156317 · ExternalCitation · doi-reference
Gouqi-derived Nanovesicles (GqDNVs) promoted MC3T3-E1 cells proliferation and improve fracture healing
10.1016/j.phymed.2025.156755 · ExternalCitation · doi-reference
Plant-derived exosomes: Unveiling the similarities and disparities between conventional extract and innovative form
10.1016/j.phymed.2025.157087 · ExternalCitation · doi-reference
Epimedium brevicornu Maxim.-derived extracellular vesicle-like particles stimulate VEGF-mediated angiogenesis to alleviate postmenopausal osteoporosis
10.1016/j.phymed.2025.157259 · ExternalCitation · doi-reference
Garlic-Derived Exosome-like Nanovesicles-Based Wound Dressing for Staphylococcus aureus Infection Visualization and Treatment
10.1021/acsabm.3c01256 · ExternalCitation · doi-reference
Morinda Officinalis-Derived Extracellular Vesicle-like Particles Promote Wound Healing via Angiogenesis
10.1021/acsami.5c01640 · ExternalCitation · doi-reference
Blueberry-derived exosomes-like nanoparticles ameliorate nonalcoholic fatty liver disease by attenuating mitochondrial oxidative stress
10.1038/s41401-021-00681-w · ExternalCitation · doi-reference
Garlic-derived exosome-like nanovesicles alleviate dextran sulphate sodium-induced mouse colitis via the TLR4/MyD88/NF-kappaB pathway and gut microbiota modulation
10.1039/d3fo01094e · ExternalCitation · doi-reference
Oral administration of cranberry-derived exosomes attenuates murine premature ovarian failure in association with changes in the specific gut microbiota and diminution in ovarian granulosa cell PANoptosis
10.1039/d4fo03468f · ExternalCitation · doi-reference
Plum-derived exosome-like nanovesicles alleviate DSS-induced colitis through gut and liver protection
10.1039/d5fo04597e · ExternalCitation · doi-reference
Current progress of plant-derived exosome-like nanovesicles on the regulation of osteoporosis and osteoarthritis
10.1080/07853890.2025.2549524 · ExternalCitation · doi-reference
Purposing plant-derived exosomes-like nanovesicles for drug delivery: patents and literature review
10.1080/13543776.2023.2195093 · ExternalCitation · doi-reference
Ginger-derived vesicle-like nanoparticles loaded with curcumin to alleviate ionizing radiation-induced intestinal damage via gut microbiota regulation
10.1080/19490976.2025.2531210 · ExternalCitation · doi-reference
The potential of plant-derived exosome-like nanovesicles from Centella asiatica leaves (CA-PDENs) for anti-inflammation and prevention of UVB-induced photoaging
10.1080/20565623.2026.2654777 · ExternalCitation · doi-reference
Bio-Inspired lipid nanovesicles (iNVs) incorporating membrane proteins from healthy tendon stem cells for targeted protein restoration in tendinopathic in vitro model
10.1080/21691401.2025.2599071 · ExternalCitation · doi-reference
Lithium chloride-treated human umbilical cord mesenchymal stem cells-derived exsomes promote hair growth by regulating miR-146a-5p-wnt pathway
10.1093/stcltm/szaf049 · ExternalCitation · doi-reference
Neuroprotective Effects of Salvia Miltiorrhiza-Derived Extracellular Nanovesicles in Traumatic Brain Injury
10.1177/08977151251383549 · ExternalCitation · doi-reference
Light modulates plant-derived extracellular vesicle properties: a photosensitive-responsive nanodelivery system
10.1186/s11671-025-04266-y · ExternalCitation · doi-reference
3D hESC exosomes enriched with miR-6766-3p ameliorates liver fibrosis by attenuating activated stellate cells through targeting the TGFbetaRII-SMADS pathway
10.1186/s12951-021-01138-2 · ExternalCitation · doi-reference
Novel plant-derived exosome-like nanovesicles from Catharanthus roseus: preparation, characterization, and immunostimulatory effect via TNF-alpha/NF-kappaB/PU.1 axis
10.1186/s12951-023-01919-x · ExternalCitation · doi-reference
Lemon-derived nanoparticle-functionalized hydrogels regulate macrophage reprogramming to promote diabetic wound healing
10.1186/s12951-025-03138-y · ExternalCitation · doi-reference
Endothelial-targeted modification of ginseng-derived exosomes for IL-6 SiRNA delivery ameliorates hepatic ischemia-reperfusion injury
10.1186/s12951-025-03954-2 · ExternalCitation · doi-reference
Garlic-derived exosome-like nanovesicle core-shell platform for sequential infection treatment and tissue repair
10.1186/s12951-026-04227-2 · ExternalCitation · doi-reference
Turmeric-derived exosome-coated ZIF-8 nanoplatform for targeted delivery of TGF-beta1 siRNA in the treatment of liver fibrosis
10.1186/s12951-026-04430-1 · ExternalCitation · doi-reference
Aloe vera-derived extracellular vesicle-like particles suppress pancreatic carcinoma progression through triggering pyroptosis via ROS-GSDMD/E signaling pathway
10.1186/s13020-025-01153-7 · ExternalCitation · doi-reference
Houttuynia cordata Thunb-derived extracellular vesicle-like particles alleviate ischemic brain injury by miR159a targeting ACSL4 to suppress ferroptosis
10.1186/s13020-025-01193-z · ExternalCitation · doi-reference
Natural Broccoli Sprout-Derived Exosomes Encapsulating Bioactive Molecules as a Novel Nanomedicine for Repair of Intestinal Inflammation
10.1208/s12248-026-01241-y · ExternalCitation · doi-reference
Garlic-Derived Exosome-Like Nanovesicles: A Promising Natural Nanotherapy for Periodontitis via PHGDH/PI3K/AKT-Mediated Metabolic and Inflammatory Regulation
10.2147/ijn.s510417 · ExternalCitation · doi-reference
Ginger-Derived Exosome-Like Nanoparticles: The Effect of Extraction Methods on Metabolites and in vitro Anti-Lung Cancer Activity
10.2147/ijn.s541948 · ExternalCitation · doi-reference
EGF-loaded, bioactive-rich Panax notoginseng-derived nanovesicles accelerate skin wound healing
10.3389/fcell.2026.1737435 · ExternalCitation · doi-reference
Edible Pueraria lobata-Derived Exosomes Promote M2 Macrophage Polarization
10.3390/molecules27238184 · ExternalCitation · doi-reference
Whitening and anti-inflammatory activities of exosomes derived from leuconostoc mesenteroides subsp. db-21 strain isolated from camellia japonica flower
10.3390/molecules30051124 · ExternalCitation · doi-reference
Topical Application of Centella asiatica in Wound Healing: Recent Insights into Mechanisms and Clinical Efficacy
10.3390/pharmaceutics16101252 · ExternalCitation · doi-reference
The dual role of extracellular vesicles derived from animal and human immune cells: A systematic review
10.5455/javar.2025.l915 · ExternalCitation · doi-reference
