Research graph
References from Sleep and Drug Use: Neuroimaging Evidence for a Multidimensional Brain Framework. Local targets link to admitted publications; unresolved targets remain external evidence.
Unresolved reference
External reference
10.15620/cdc/174639
10.15620/cdc/174639 · External reference
Neurobiology of addiction: a neurocircuitry analysis
10.1016/s2215-0366(16)00104-8 · 2016 · External reference
10.1016/b978-0-12-815501-1.00015-6
10.1016/b978-0-12-815501-1.00015-6 · External reference
Rest-Activity Rhythms, Their Modulators, and Brain-Clinical Correlates in Opioid Use Disorder
10.1001/jamanetworkopen.2024.57976 · 2025 · External reference
Multidimensional sleep health domains in older men and women: an actigraphy factor analysis
10.1093/sleep/zsaa181 · 2021 · External reference
An Aggregate Measure of Sleep Health Is Associated With Prevalent and Incident Clinically Significant Depression Symptoms Among Community-Dwelling Older Women
10.1093/sleep/zsw075 · 2017 · External reference
Unresolved reference
External reference
A continuous approach to explain insomnia and subjective-objective sleep discrepancy
10.1038/s42003-025-07794-6 · 2025 · External reference
Intraindividual variability in sleep among people with insomnia and its relationship with sleep, health and lifestyle factors: an exploratory study
10.1016/j.sleep.2021.12.006 · 2022 · External reference
Association between insomnia symptoms and chronotype—A systematic review and meta-analysis
10.1016/j.sleh.2025.06.011 · 2025 · External reference
Sleep changes in the disorder of insomnia: A meta-analysis of polysomnographic studies
10.1016/j.smrv.2013.04.001 · 2014 · External reference
Insomnia Subtypes Have Differentiating Deviations in Brain Structural Connectivity
10.1016/j.biopsych.2024.06.014 · 2025 · External reference
Local modulation of human brain responses by circadian rhythmicity and sleep debt
10.1126/science.aad2993 · 2016 · External reference
Human Sleep: Its Duration and Organization Depend on Its Circadian Phase
10.1126/science.7434029 · 1980 · External reference
Brain mechanisms of insomnia: new perspectives on causes and consequences
10.1152/physrev.00046.2019 · 2021 · External reference
Sleep disturbance and psychiatric disorders: A longitudinal epidemiological study of young Adults
10.1016/0006-3223(95)00188-3 · 1996 · External reference
Adolescent Insomnia as a Risk Factor for Early Adult Depression and Substance Abuse
2008 · External reference
Prospective Relationship Between Poor Sleep and Substance-Related Problems in a National Sample of Adolescents
10.1111/acer.12618 · 2015 · External reference
Changes in Rest-Activity Rhythms in Adolescents as They Age: Associations With Brain and Behavioral Changes in the ABCD Study
10.1016/j.jaac.2024.11.005 · 2025 · External reference
Self-reported sleep and circadian characteristics predict alcohol and cannabis use: A longitudinal analysis of the National Consortium on Alcohol and Neurodevelopment in Adolescence study
10.1111/acer.14808 · 2022 · External reference
Relationships between hours of sleep and health-risk behaviors in US adolescent students
10.1016/j.ypmed.2011.06.020 · 2011 · External reference
Sleep and use of alcohol and drug in adolescence. A large population-based study of Norwegian adolescents aged 16 to 19 years
10.1016/j.drugalcdep.2015.01.045 · 2015 · External reference
Sleep regularity in adolescents: Associations with sleep, rest-activity indices, and prospective substance use and depression
10.1111/jsr.14468 · 2025 · External reference
Adolescent substance use and its association to sleep disturbances: A systematic review
10.1016/j.sleh.2019.06.001 · 2019 · External reference
Clinical characterization of insomnia in adolescents – an integrated approach to psychopathology
10.1016/j.sleep.2022.03.010 · 2022 · External reference
Chronotype and Mental Health: Are Late Sleepers More Vulnerable?
10.1007/s11920-025-01626-4 · 2025 · External reference
Restless Sleep and Variable Sleep Timing During Late Childhood Accelerate the Onset of Alcohol and Other Drug Involvement
10.15288/jsad.2016.77.649 · 2016 · External reference
Effects of sleep on substance use in adolescents: a longitudinal perspective
10.1111/adb.12519 · 2018 · External reference
Prior sleep-wake behaviors are associated with mental health outcomes during the COVID-19 pandemic among adult users of a wearable device in the United States
10.1016/j.sleh.2022.03.001 · 2022 · External reference
Dopamine D1 and D2 receptors are distinctly associated with rest-activity rhythms and drug reward
10.1172/jci149722 · 2021 · External reference
Brain charts for the human lifespan
10.1038/s41586-022-04554-y · 2022 · External reference
Insomnia is Associated with Cortical Hyperarousal as Early as Adolescence
10.5665/sleep.5746 · 2016 · External reference
Functional Neuroimaging Evidence for Hyperarousal in Insomnia
10.1176/appi.ajp.161.11.2126 · 2004 · External reference
Unresolved reference
External reference
How Late Nights Influence Brain Cortical Structures: Distinct Neuroanatomical Measures Associated With Late Chronotype in Young Adults
10.1007/s10548-024-01085-9 · 2024 · External reference
Multimodal population study reveals the neurobiological underpinnings of chronotype
10.1038/s41562-025-02182-w · 2025 · External reference
Functional brain connectivity predicts sleep duration in youth and adults
10.1002/hbm.26488 · 2023 · External reference
Effects of sleep duration on neurocognitive development in early adolescents in the USA: a propensity score matched, longitudinal, observational study
10.1016/s2352-4642(22)00188-2 · 2022 · External reference
Decreased sleep is linked longitudinally and directionally to alterations in the brain’s intrinsic functional architecture
10.1016/j.dcn.2025.101668 · 2026 · External reference
Neuroimaging subtypes of adolescent sleep insufficiency stratify natural short sleepers from comorbidity or environment driven insufficiency
2026 · External reference
No phenotypic or genotypic evidence for a link between sleep duration and brain atrophy
10.1038/s41562-023-01707-5 · 2023 · External reference
Impact of sleep duration on executive function and brain structure
10.1038/s42003-022-03123-3 · 2022 · External reference
Dynamic mapping of human cortical development during childhood through early adulthood
10.1073/pnas.0402680101 · 2004 · External reference
Sleep and Human Aging
10.1016/j.neuron.2017.02.004 · 2017 · External reference
Patterns of brain-wide associations reflect socioeconomics
10.1126/science.aee6213 · 2026 · External reference
Mapping the Neural Basis of Wake Onset Regularity and Its Effects on Sleep Quality and Positive Affect
10.3390/clockssleep7010015 · 2025 · External reference
Sleep/Wake Regularity Associated with Default Mode Network Structure among Healthy Adolescents and Young Adults
10.1038/s41598-019-57024-3 · 2020 · External reference
Irregular sleep habits, regional grey matter volumes, and psychological functioning in adolescents
10.1371/journal.pone.0243720 · 2021 · External reference
Sleep inconsistency between weekends and weekdays is associated with changes in brain function during task and rest
2020 · External reference
Orbitofrontal volumes in early adolescence predict initiation of cannabis use: a 4-year longitudinal and prospective study
10.1016/j.biopsych.2011.10.029 · 2012 · External reference
Multi-level patterns predict cannabis use onset among youth
10.1016/j.dcn.2025.101639 · 2025 · External reference
Neuroanatomical Variability and Substance Use Initiation in Late Childhood and Early Adolescence
10.1001/jamanetworkopen.2024.52027 · 2024 · External reference
Functional Brain Connectivity Predictors of Prospective Substance Use Initiation and Their Environmental Correlates
2025 · External reference
In the face of ambiguity: intrinsic brain organization in development predicts one’s bias toward positivity or negativity
10.1093/cercor/bhae102 · 2024 · External reference
Task and Resting-State Functional Magnetic Resonance Imaging Modeling of Brain-Behavior Relationships in Developmental Cohorts
10.1016/j.biopsych.2025.09.012 · 2026 · External reference
Multimodal neural correlates of childhood psychopathology
10.7554/elife.87992 · 2024 · External reference
Sensitive periods of substance abuse: Early risk for the transition to dependence
10.1016/j.dcn.2016.10.004 · 2017 · External reference
Brain lesions disrupting addiction map to a common human brain circuit [no. 6]
10.1038/s41591-022-01834-y · 2022 · External reference
Insomnia symptoms and neurofunctional correlates among adults receiving buprenorphine for opioid use disorder
10.1371/journal.pone.0304461 · 2024 · External reference
Assessment and treatment of insomnia in adult patients with alcohol use disorders
10.1016/j.alcohol.2014.12.003 · 2015 · External reference
Insomnia, self-medication, and relapse to alcoholism
10.1176/appi.ajp.158.3.399 · 2001 · External reference
Sleep Regularity Index in Patients with Alcohol Dependence: Daytime Napping and Mood Disorders as Correlates of Interest
10.3390/ijerph17010331 · 2020 · External reference
A lower sleep regularity index (SRI) is associated with relapse in individuals with alcohol use disorder following inpatient treatment
10.1038/s41598-022-26019-y · 2022 · External reference
Sleep abnormalities associated with alcohol, cannabis, cocaine, and opiate use: a comprehensive review
10.1186/s13722-016-0056-7 · 2016 · External reference
Increased Pressure for Rapid Eye Movement Sleep at Time of Hospital Admission Predicts Relapse in Nondepressed Patients With Primary Alcoholism at 3-Month Follow-up
10.1001/archpsyc.1994.03950030025003 · 1994 · External reference
Slow wave sleep: a predictor of individual differences in response to drinking?
1980 · External reference
Effect of detoxification on N3 sleep correlates with brain functional but not structural changes in alcohol use disorder
10.1016/j.drugalcdep.2022.109545 · 2022 · External reference
Actigraphy-based sleep outcomes in substance use disorders: A systematic review and meta-analysis
10.1016/j.smrv.2026.102297 · 2026 · External reference
Sleep alterations in substance use disorders: a systematic review and meta-analysis
10.1016/j.eclinm.2025.103723 · 2026 · External reference
Brain glutamate and sleep efficiency associations following a ketogenic diet intervention in individuals with Alcohol Use Disorder
10.1016/j.dadr.2022.100092 · 2022 · External reference
Sleepiness and sleep state on a 90-min schedule
10.1111/j.1469-8986.1977.tb03362.x · 1977 · External reference
Circadian clues to sleep onset mechanisms
10.1016/s0893-133x(01)00315-3 · 2001 · External reference
The hyperarousal model of insomnia: a review of the concept and its evidence
10.1016/j.smrv.2009.04.002 · 2010 · External reference
Spectral characteristics of sleep EEG in chronic insomnia
10.1046/j.1460-9568.1998.00189.x · 1998 · External reference
Human data at odds and in confirmation of the two-process model of sleep regulation—a perspective
10.1038/s44323-026-00083-3 · 2026 · External reference
10.1073/pnas.2016732119
10.1073/pnas.2016732119 · External reference
Development of a Large-Scale Functional Brain Network during Human Non-Rapid Eye Movement Sleep
10.1523/jneurosci.2015-10.2010 · 2010 · External reference
Regulation of cortical activity and arousal by the matrix cells of the ventromedial thalamic nucleus
10.1038/s41467-018-04497-x · 2018 · External reference
The sleep switch: hypothalamic control of sleep and wakefulness
10.1016/s0166-2236(00)02002-6 · 2001 · External reference
Sleep disturbances are associated with cortical and subcortical atrophy in alcohol use disorder
10.1038/s41398-021-01534-0 · 2021 · External reference
Cortical hierarchy underlying homeostatic sleep pressure alleviation
10.1038/s41467-025-64989-5 · 2025 · External reference
Regional Cerebral Blood Flow Changes as a Function of Delta and Spindle Activity during Slow Wave Sleep in Humans
10.1523/jneurosci.17-12-04800.1997 · 1997 · External reference
Simultaneous EEG-PET-MRI identifies temporally coupled and spatially structured brain dynamics across wakefulness and NREM sleep
10.1038/s41467-025-64414-x · 2025 · External reference
Impact of Alcoholism on Sleep Architecture and EEG Power Spectra in Men and Women
10.1093/sleep/32.10.1341 · 2009 · External reference
Human Regional Cerebral Blood-Flow During Rapid-Eye-Movement Sleep
10.1038/jcbfm.1991.94 · 1991 · External reference
Localized and Lateralized Cerebral Glucose Metabolism Associated With Eye Movements During REM Sleep and Wakefulness: A Positron Emission Tomography (PET) Study
10.1093/sleep/18.7.570 · 1995 · External reference
Functional neuroanatomy of human rapid-eye-movement sleep and dreaming
10.1038/383163a0 · 1996 · External reference
Forebrain activation in REM sleep: an FDG PET study
10.1016/s0006-8993(97)00807-x · 1997 · External reference
The impact of REM sleep loss on human brain connectivity
10.1038/s41398-024-02985-x · 2024 · External reference
Gray and white matter morphology in substance use disorders: a neuroimaging systematic review and meta-analysis
10.1038/s41398-020-01128-2 · 2021 · External reference
Mega-Analysis of Gray Matter Volume in Substance Dependence: General and Substance-Specific Regional Effects
10.1176/appi.ajp.2018.17040415 · 2019 · External reference
Heterogeneous neuroimaging findings across substance use disorders localize to a common brain network [no. 10]
10.1038/s44220-023-00128-7 · 2023 · External reference
Brain Function Outcomes of Recent and Lifetime Cannabis Use
10.1001/jamanetworkopen.2024.57069 · 2025 · External reference
Common and separable neural alterations in substance use disorders: A coordinate-based meta-analyses of functional neuroimaging studies in humans
10.1002/hbm.25085 · 2020 · External reference
Associations of thalamocortical networks with reduced mindfulness in alcohol use disorder
10.3389/fpsyt.2023.1123204 · 2023 · External reference
Reduced thalamic resting‐state functional connectivity and impaired cognition in acute abstinent heroin users
10.1002/hbm.25346 · 2021 · External reference
Brain default-mode network dysfunction in addiction
10.1016/j.neuroimage.2019.06.036 · 2019 · External reference
Substance-Specific and Shared Gray Matter Signatures in Alcohol, Opioid, and Polysubstance Use Disorder
10.3389/fpsyt.2021.795299 · 2022 · External reference
Mega-analysis of the brain-age gap in substance use disorder: An ENIGMA Addiction working group study
10.1111/add.16621 · 2024 · External reference
The effect of alcohol withdrawal syndrome severity on sleep, brain and cognition
10.1093/braincomms/fcaa123 · 2020 · External reference
Alcohol use disorder and sleep disturbances: a feed-forward allostatic framework
2019 · External reference
