Research graph
References from Mathematical modeling and intelligent methods in systems biology and medicine applied to complex diseases: An overview. Local targets link to admitted publications; unresolved targets remain external evidence.
Detection of haplotype-dependent allele-specific dna methylation in wgbs data
10.1038/s41467-020-19077-1 · 2020 · External reference
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2026 · External reference
Boolean modeling of genetic regulatory networks
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Unresolved reference
2024 · External reference
Unresolved reference
1964 · External reference
Network medicine: A network-based approach to human disease
10.1038/nrg2918 · 2011 · External reference
Cancer growth and metastasis as a metaphor of go gaming: An ising model approach
2018 · External reference
Cancer growth and metastasis as a metaphor of go gaming: An ising model approach
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The nested assembly of plant-animal mutualistic networks
10.1073/pnas.1633576100 · 2003 · External reference
Higher-order interactions in statistical physics and machine learning: A model-independent solution to the inverse problem at equilibrium
10.1103/physreve.102.053314 · 2020 · External reference
Classical mathematical models for description and prediction of experimental tumor growth
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Quantitative laws in metabolism and growth
10.1086/401873 · 1957 · External reference
Cellular automata microsimulation for modeling bi-directional pedestrian walkways
10.1016/s0191-2615(99)00052-1 · 2001 · External reference
Cellular potts model: Applications to vasculogenesis and angiogenesis
2018 · External reference
Random forests
10.1023/a:1010933404324 · 2001 · External reference
Radial basis functions, multi-variable functional interpolation and adaptive networks
1988 · External reference
Ising-like model for tumor growth
1997 · External reference
Support vector machine applications in bioinformatics
2003 · External reference
A comprehensive survey on support vector machine classification: Applications, challenges and trends
10.1016/j.neucom.2019.10.118 · 2020 · External reference
Deep learning tools to accelerate antibiotic discovery
10.1080/17460441.2023.2250721 · 2023 · External reference
Challenges and applications of artificial intelligence in infectious diseases and antimicrobial resistance
2025 · External reference
Random forests for genomic data analysis
2019 · External reference
Violent behavior and the network properties of psychopathological symptoms and real-life functioning in patients with schizophrenia
10.3389/fpsyt.2023.1324911 · 2024 · External reference
A self-organizing model for forest fire spread
1997 · External reference
A practical method for numerical evaluation of solutions of partial differential equations
10.1017/s0305004100023197 · 1947 · External reference
Cloud mapreduce for monte carlo bootstrap applied to metabolic flux analysis
10.1016/j.future.2011.10.007 · 2013 · External reference
Functional and transcriptional connectivity of communities in breast cancer co-expression networks
10.1007/s41109-019-0129-0 · 2019 · External reference
Multiscale cancer modeling
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Statistical field theory of the transmission of nerve impulses
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Machine learning in medicine
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Unresolved reference
2000 · External reference
Cancer immunoediting: from immunosurveillance to tumor escape
10.1038/ni1102-991 · 2002 · External reference
Is symptom connectivity really the most important issue in depression? depression as a dynamic system of interconnected symptoms revisited
10.1016/j.jpsychires.2021.08.004 · 2021 · External reference
Gene regulatory network modeling of the central dogma of molecular biology: A review
2017 · External reference
Dermatologist-level classification of skin cancer with deep neural networks
10.1038/nature21056 · 2017 · External reference
Stochastic modeling of tumor-immune interactions reveals critical transitions in immune evasion
2022 · External reference
Network analysis of multimorbidity and health outcomes among persons with spinal cord injury in Canada
10.3389/fneur.2023.1286143 · 2024 · External reference
Application of artificial intelligence-based computer vision methods in liver diseases: A bibliometric analysis
10.1016/j.imed.2024.09.008 · 2025 · External reference
Incretin-based drugs as potential therapy for neurodegenerative diseases: current status and perspectives
10.1016/j.pharmthera.2022.108277 · 2022 · External reference
Fibroblast-specific protein-protein interactions for myocardial fibrosis from metacore network
10.3390/biom14111395 · 2024 · External reference
Using bayesian networks to analyze expression data
10.1089/106652700750050961 · 2000 · External reference
Unresolved reference
2009 · External reference
The impact of cellular characteristics on the evolution of tumor shape
2013 · External reference
The role of artificial intelligence in cardio-oncology
2025 · External reference
Unresolved reference
2003 · External reference
Evolutionary game theory approach to resource-consumer dynamics in economic systems
2020 · External reference
Shaping the future of healthcare: Ethical clinical challenges and pathways to trustworthy ai
10.3390/jcm14051605 · 2025 · External reference
Unresolved reference
2016 · External reference
Stochastic dynamics of predator–prey systems with random environmental fluctuations
2020 · External reference
Unresolved reference
2024 · External reference
Unresolved reference
2020 · External reference
Unresolved reference
1996 · External reference
Hallmarks of cancer: New dimensions
10.1158/2159-8290.cd-21-1059 · 2022 · External reference
The hallmarks of cancer
10.1016/s0092-8674(00)81683-9 · 2000 · External reference
Hallmarks of cancer: the next generation
10.1016/j.cell.2011.02.013 · 2011 · External reference
Future of artificial intelligence - machine learning trends in pathology and medicine
10.1016/j.modpat.2025.100705 · 2025 · External reference
A comprehensive review of artificial intelligence models for screening major retinal diseases
10.1007/s10462-024-10736-z · 2024 · External reference
Unresolved reference
1997 · External reference
The mathematics of infectious diseases
10.1137/s0036144500371907 · 2000 · External reference
Tumour-mediated upregulation of chemoattractants and recruitment of myeloid cells predetermines lung metastasis
10.1038/ncb1507 · 2006 · External reference
Some characteristics of simple types of predation and parasitism
1959 · External reference
Systems biology and p4 medicine: past, present, and future
2012 · External reference
Unresolved reference
2013 · External reference
A review of artificial intelligence for predicting climate driven infectious disease outbreaks to enhance global health resilience
2025 · External reference
Phase transition in tumor growth: I avascular development
10.1016/j.physa.2013.08.010 · 2013 · External reference
Use of artificial intelligence including multimodal systems to improve the management of cardiovascular disease
2024 · External reference
Unresolved reference
2013 · External reference
Emergent behaviors from a cellular automaton model for invasive tumor growth in heterogeneous microenvironments
10.1371/journal.pcbi.1002314 · 2011 · External reference
Diversity of dynamics and morphologies of invasive solid tumors
10.1063/1.3697959 · 2012 · External reference
Physics-informed machine learning
10.1038/s42254-021-00314-5 · 2021 · External reference
Metabolic stability and epigenesis in randomly constructed genetic nets
10.1016/0022-5193(69)90015-0 · 1969 · External reference
Unresolved reference
2008 · External reference
A contribution to the mathematical theory of epidemics
10.1098/rspa.1927.0118 · 1927 · External reference
Artificial intelligence in the care of children and adolescents with chronic diseases: A systematic review
2024 · External reference
The impact of artificial intelligence on allergy diagnosis and treatment
10.1007/s11882-024-01152-y · 2024 · External reference
Unresolved reference
2018 · External reference
Reliability of energy landscape analysis of resting-state functional mri data
10.1111/ejn.16390 · 2024 · External reference
Control analysis of metabolic systems involving quasi-equilibrium reactions
10.1016/s0304-4165(97)00114-1 · 1998 · External reference
Regular and irregular patterns in semiarid vegetation
10.1126/science.284.5421.1826 · 1999 · External reference
Unresolved reference
2009 · External reference
Stochastic modeling of cellular colonies with quiescence: An application to drug treatment
2004 · External reference
Reaction–diffusion model as a framework for understanding biological pattern formation
10.1126/science.1179047 · 2010 · External reference
Cancer systems biology: A network modeling perspective
10.1093/carcin/bgp261 · 2010 · External reference
A modified ising model of barabasi-albert network with gene-type spins
10.1007/s00285-020-01518-6 · 2020 · External reference
Can local heating and molecular crowders disintegrate amyloid aggregates?
10.1039/d4sc00103f · 2024 · External reference
Demographic models of the northern spotted owl
10.1007/bf00776426 · 1988 · External reference
Deep learning
10.1038/nature14539 · 2015 · External reference
Microscopic simulation of the stock market: The effect of microscopic diversity
2000 · External reference
Current applications of artificial intelligence in sarcoidosis
10.1007/s00408-023-00641-7 · 2023 · External reference
A survey on deep learning in medical image analysis
10.1016/j.media.2017.07.005 · 2017 · External reference
Novel strategies for cancer immunotherapy: counter-immunoediting therapy
10.1186/s13045-023-01430-8 · 2023 · External reference
Antimicrobial resistance crisis: could artificial intelligence be the solution?
2024 · External reference
Phase transitions in tumor growth: Iii vascular and metastasis behavior
10.1016/j.physa.2016.06.086 · 2016 · External reference
Unresolved reference
1925 · External reference
Machine learning models for prognosis prediction in regenerative endodontic procedures
10.1186/s12903-025-05531-3 · 2025 · External reference
Learning nonlinear operators via deeponet based on the universal approximation theorem of operators
10.1038/s42256-021-00302-5 · 2021 · External reference
Diagnostic performance of fetal intelligent navigation echocardiography (fine) in fetuses with double-outlet right ventricle (dorv)
10.1007/s10554-020-01932-3 · 2020 · External reference
Unresolved reference
External reference
Enhanced simulations of whole-brain dynamics using hybrid resting-state structural connectomes
10.3389/fncom.2023.1295395 · 2023 · External reference
A deep-learning view of chemical space designed to facilitate drug discovery
10.1021/acs.jcim.0c00321 · 2020 · External reference
Unresolved reference
1906 · External reference
Main genes in breast cancer primary tumor and first metastasis in lymph nodes revealed by information-theory-based genetic networks pattern analysis
10.1016/j.patrec.2024.07.006 · 2024 · External reference
Defining and analysis of multimorbidity pattern of diseases using markov random field approach: A comparative analysis
2022 · External reference
Evolving synergistic combinations of targeted immunotherapies to combat cancer
10.1038/nrc3973 · 2014 · External reference
The monte carlo method
10.1080/01621459.1949.10483310 · 1949 · External reference
Deep learning for healthcare: review, opportunities and challenges
10.1093/bib/bbx044 · 2018 · External reference
Artificial intelligence in clinical medicine: A state-of-the-art overview of systematic reviews with methodological recommendations for improved reporting
2025 · External reference
Mathematical biology: I. An introduction
10.1007/b98868 · 2002 · External reference
Cellular automaton model for freeway traffic
1992 · External reference
Markov models of metastatic tumor progression
2005 · External reference
A stochastic markov chain model to describe lung cancer growth and metastasis
10.1371/journal.pone.0034637 · 2012 · External reference
Markov modeling of metastatic progression
2020 · External reference
Spreaders and sponges define metastasis in lung cancer: A markov chain monte carlo mathematical model
10.1158/0008-5472.can-12-4488 · 2013 · External reference
Entropy, complexity, and markov diagrams for random walk cancer models
10.1038/srep07558 · 2014 · External reference
Spatiotemporal progression of metastatic breast cancer: A markov chain model highlighting the role of early metastatic sites
10.1038/npjbcancer.2015.18 · 2015 · External reference
Spatiotemporal bayesian networks for modeling disease progression
2015 · External reference
A stochastic markov chain model to describe lung cancer growth and metastasis
10.1371/journal.pone.0034637 · 2012 · External reference
Bayesian latent ising model for joint microbial and metabolomic network inference
10.1080/02664763.2026.2636648 · 2026 · External reference
Extended thermodynamic approach to tumor growth
2006 · External reference
Longevity, aging and cancer: Thermodynamics and complexity
10.3390/foundations2030045 · 2022 · External reference
Nonlinear dynamics and chaos in tumor growth models
2008 · External reference
Entropy production rate as a lyapunov function in chemical systems: Proof
10.1238/physica.regular.068a00163 · 2003 · External reference
Support vector machine applications in computational biology
2006 · External reference
Rise of the machines - artificial intelligence in healthcare epidemiology
10.1007/s11908-024-00854-8 · 2025 · External reference
Theory of tumor growth
1976 · External reference
Cancer immunoediting and resistance to t cell-based immunotherapy
10.1038/s41571-018-0142-8 · 2019 · External reference
Unresolved reference
2025 · External reference
Unresolved reference
2013 · External reference
Unresolved reference
1996 · External reference
Video-based ai for beat-to-beat assessment of cardiac function
10.1038/s41586-020-2145-8 · 2020 · External reference
Models of stochastic gene expression
10.1016/j.plrev.2005.03.003 · 2005 · External reference
Unresolved reference
1988 · External reference
Pre-metastatic niches: organ-specific homes for metastases
10.1038/nrc.2017.6 · 2017 · External reference
Unresolved reference
2011 · External reference
A network analysis of anxiety and depression symptoms among chinese nurses in the late stage of the covid-19 pandemic
2022 · External reference
Modelling viral and immune system dynamics
10.1038/nri700 · 2002 · External reference
Uncertainty and the management of multistate ecosystems: An example from grand canyon
2003 · External reference
Radial basis functions for multivariable interpolation: A review
1987 · External reference
Physics-informed neural networks: A deep learning framework for solving forward and inverse problems involving nonlinear partial differential equations
10.1016/j.jcp.2018.10.045 · 2019 · External reference
Ai in health and medicine
10.1038/s41591-021-01614-0 · 2022 · External reference
Machine learning and artificial intelligence for the analysis of large-scale complex biological data
2019 · External reference
Unresolved reference
2004 · External reference
Associations of hospitalisation - admission, readmission and length to stay - with multimorbidity patterns by age and sex in adults and older adults: the elsi-brazil study
10.1186/s12877-023-04167-8 · 2023 · External reference
Modeling cancer immunoediting in tumor microenvironment with system characterization through the ising-model hamiltonian
10.1186/s12859-022-04731-w · 2022 · External reference
Modeling and simulation of genotypic tumor mutational burden and phenotypic immunogenicity biomarkers in cancer immunoediting with ising-hamiltonian characterization
10.1016/j.compbiomed.2025.109717 · 2025 · External reference
Graphical representation and stability conditions of predator–prey interactions
10.1086/282272 · 1963 · External reference
Lsd-induced increase of ising temperature and algorithmic complexity of brain dynamics
10.1371/journal.pcbi.1010811 · 2023 · External reference
Bayesian network approach to cell signaling pathway modeling
2005 · External reference
Cancer niches and their kikuchi free energy
10.3390/e23050609 · 2021 · External reference
Ising-like modeling of cancer niche construction: Two-dimensional analysis
2020 · External reference
Unresolved reference
2001 · External reference
Artificial intelligence, computational simulations, and extended reality in cardiovascular interventions
2023 · External reference
Deep learning in neural networks: An overview
10.1016/j.neunet.2014.09.003 · 2015 · External reference
Personalized medicine: time for one-person trials
10.1038/520609a · 2015 · External reference
Artificial intelligence system reduces false-positive findings in the interpretation of breast ultrasound exams
10.1038/s41467-021-26023-2 · 2021 · External reference
Integrating clinical and multiomics evidence based on disease module theory: deciphering the comorbidity network of psoriasis vulgaris via the ising model for mechanistic insights
2026 · External reference
Boolean networks with probabilistic dynamics
2003 · External reference
10.1109/eit.2018.8500205
10.1109/eit.2018.8500205 · External reference
Probabilistic climate projections with neural networks
2009 · External reference
Pastoralscape: An environment-driven model of vaccination decision making within pastoralist groups in East Africa
2021 · External reference
Ising model of choriocapillaris flow
2018 · External reference
Epipredict: Agent-based modeling of infectious diseases
10.1007/s13218-023-00819-4 · 2024 · External reference
Prevalence and network structure of depression, insomnia and suicidality among mental health professionals who recovered from covid-19: A national survey in China
10.1038/s41398-024-02918-8 · 2024 · External reference
Unresolved reference
2018 · External reference
Quantitative analysis of glioma cell invasion
10.1016/j.jns.2003.06.001 · 2003 · External reference
Hybrid time series and machine learning models for forecasting cardiovascular mortality in India: An age specific analysis
2025 · External reference
Two-stage augmentation for detecting malignancy of bi-rads 3 lesions in early breast cancer
10.1186/s12885-025-13960-0 · 2025 · External reference
High-performance medicine: the convergence of human and artificial intelligence
10.1038/s41591-018-0300-7 · 2019 · External reference
Toward an ising model of cancer and beyond
10.1088/1478-3975/8/1/015017 · 2011 · External reference
Perspective: Sloppiness and emergent theories in physics, biology, and beyond
10.1063/1.4923066 · 2015 · External reference
A formal validation of a deep learning-based automated workflow for the interpretation of the echocardiogram
2022 · External reference
Automated interpretation of systolic and diastolic function on the echocardiogram: A multicohort study
10.1016/s2589-7500(21)00235-1 · 2022 · External reference
The chemical basis of morphogenesis
1952 · External reference
Random processes and the monte carlo method
1949 · External reference
Attention is all you need
2017 · External reference
Notice sur la loi que la population poursuit dans son accroissement
1838 · External reference
Translational systems biology of inflammation and healing
2010 · External reference
Variazioni e fluttuazioni del numero d’individui in specie animali conviventi
1926 · External reference
Unresolved reference
1966 · External reference
Mathematical modeling in complex diseases: A review of applications, challenges, and opportunities
2016 · External reference
Stochastic analysis of predator–prey models with lévy noise and impulsive effects
2021 · External reference
Automated interpretation of congenital heart disease from multi-view echocardiograms
10.1016/j.media.2020.101942 · 2021 · External reference
A note on the reverse michaelis-menten kinetics
10.1016/j.soilbio.2012.08.028 · 2013 · External reference
A statistical physics approach for disease module detection
2022 · External reference
Automatic learning of mortality in a cpn model of the systemic inflammatory response syndrome
10.1016/j.mbs.2016.11.004 · 2017 · External reference
The cellular ising model: A framework for phase transitions in multicellular environments
10.1098/rsif.2015.1092 · 2016 · External reference
Unresolved reference
2014 · External reference
Unresolved reference
2011 · External reference
Leveraging artificial intelligence in the fight against infectious diseases
10.1126/science.adh1114 · 2023 · External reference
Robust and efficient semi-supervised learning for ising model
10.1093/biomtc/ujaf060 · 2025 · External reference
Integrating artificial intelligence with mechanistic epidemiological modeling: A scoping review of opportunities and challenges
2025 · External reference
Immunological drug–drug interactions in immune checkpoint inhibitor therapy: Mechanisms, clinical evidence, and artificial intelligence
2026 · External reference
Structural knowledge: from brain to artificial intelligence
2025 · External reference
How does the covid-19 pandemic impact on population mental health? A network analysis of covid influences on depression, anxiety and traumatic stress in the UK population
10.1017/s0033291721000635 · 2022 · External reference
Fully automated echocardiogram interpretation in clinical practice
10.1161/circulationaha.118.034338 · 2018 · External reference
Multi-neurotransmitter synergistically regulated basal ganglia reinforcement learning model
10.1016/j.neunet.2026.108941 · 2026 · External reference
On-line prediction of products concentrations in glutamate fermentation using metabolic network model and linear programming
10.1016/j.bej.2005.03.012 · 2005 · External reference
Bayesian compositional regression with structured priors for microbiome feature selection
10.1111/biom.13335 · 2021 · External reference
Data-driven-based approach to identifying differentially methylated regions using modified 1d ising model
10.1155/2018/1070645 · 2018 · External reference
Unresolved reference
2012 · External reference
Identification of microbial interaction network: zero-inflated latent ising model based approach
10.1186/s13040-020-00226-7 · 2020 · External reference
Deciphering the coevolutionary dynamics of l2 β-lactamases via deep learning
10.1021/acs.jcim.4c00189 · 2024 · External reference
Allergen sensitization profiles and co-sensitization networks in children with allergic rhinitis and asthma: A propensity score-matched retrospective study
10.2147/jaa.s620785 · 2026 · External reference
