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References from Programmable microalgae: Engineering sense–decide–adapt systems for dynamic environmental performance. Local targets link to admitted publications; unresolved targets remain external evidence.
Flashing light in microalgae biotechnology
10.1016/j.biortech.2015.12.057 · 2016 · External reference
Acclimation of thermotolerant algae to light and temperature interaction
10.1111/jpy.12964 · 2020 · External reference
Exogenous abscisic acid confers salinity tolerance in Chlamydomonas reinhardtii during its life cycle
10.1111/jpy.13174 · 2021 · External reference
Light-independent regulation of algal photoprotection by CO2 availability
10.1038/s41467-023-37800-6 · 2023 · External reference
Lipid production in Nannochloropsis gaditana is doubled by decreasing expression of a single transcriptional regulator
10.1038/nbt.3865 · 2017 · External reference
A cybergenetic framework for engineering intein-mediated integral feedback control systems
10.1038/s41467-023-36863-9 · 2023 · External reference
Widening the landscape of transcriptional regulation of green algal photoprotection
10.1038/s41467-023-38183-4 · 2023 · External reference
Dynamic, autonomous gene expression system for self-adaptation and self-regulation in microbial production
10.1016/j.biotechadv.2026.108889 · 2026 · External reference
Expanding the upper-temperature boundary for the microalga Picochlorum sp. (BPE23) by adaptive laboratory evolution
10.1002/biot.202100659 · 2022 · External reference
Growth dependent silencing and resetting of DGA1 transgene in Nannochloropsis salina
10.1016/j.algal.2016.01.005 · 2016 · External reference
Inositol polyphosphates regulate resilient mechanisms in the green alga Chlamydomonas reinhardtii to adapt to extreme nutrient conditions
10.1111/ppl.70089 · 2025 · External reference
The role of glycerol in osmotic regulation of the halophilic alga Dunaliella parva
10.1104/pp.51.5.875 · 1973 · External reference
Analysis of Lhcsr3, a protein essential for feedback de-excitation in the green alga Chlamydomonas reinhardtii
10.1074/jbc.m111.304279 · 2012 · External reference
Dynamic metabolic engineering: new strategies for developing responsive cell factories
10.1002/biot.201400422 · 2015 · External reference
Unlocking the algae toolbox: cutting-edge tools for environmental and biotechnological solutions
10.1016/j.biotechadv.2025.108652 · 2025 · External reference
Alternative photosynthesis pathways drive the algal CO2-concentrating mechanism
10.1038/s41586-022-04662-9 · 2022 · External reference
Epigenetic dynamics in Chlamydomonas: new frontiers in unicellular algal research
10.1016/j.tplants.2025.08.013 · 2026 · External reference
Alternative pathway to photorespiration protects growth and productivity at elevated temperatures in a model crop
10.1111/pbi.13750 · 2022 · External reference
Burden-driven feedback control of gene expression
10.1038/nmeth.4635 · 2018 · External reference
Synergism between inositol polyphosphates and TOR kinase signaling in nutrient sensing, growth control, and lipid metabolism in Chlamydomonas
10.1105/tpc.16.00351 · 2016 · External reference
Inositol polyphosphates and target of rapamycin kinase signalling govern photosystem II protein phosphorylation and photosynthetic function under light stress in Chlamydomonas
10.1111/nph.17741 · 2021 · External reference
Genome engineering empowers the diatom Phaeodactylum tricornutum for biotechnology
10.1038/ncomms4831 · 2014 · External reference
A synchronized quorum of genetic clocks
10.1038/nature08753 · 2010 · External reference
The green algae CO2-concentrating mechanism and photorespiration jointly operate during acclimation to low CO2
10.1038/s41467-025-60525-7 · 2025 · External reference
Navigating microalgae under dynamic CO2 for waste-to-energy conversion
10.1016/j.tibtech.2025.06.014 · 2025 · External reference
Synchronized cycles of bacterial lysis for in vivo delivery
10.1038/nature18930 · 2016 · External reference
Chassis engineering for high light tolerance in microalgae and cyanobacteria
10.1080/07388551.2024.2357368 · 2025 · External reference
Molecular design of microalgae as sustainable cell factories
10.1016/j.tibtech.2023.11.010 · 2024 · External reference
A synthetic oscillatory network of transcriptional regulators
10.1038/35002125 · 2000 · External reference
Toward a modeling, optimization, and predictive control framework for fed-batch metabolic cybergenetics
10.1002/bit.28575 · 2024 · External reference
Resolving the consequences of gradual phenotypic plasticity for populations in variable environments
10.1002/ecm.1478 · 2021 · External reference
The eukaryotic CO2-concentrating organelle is liquid-like and exhibits dynamic reorganization
10.1016/j.cell.2017.08.008 · 2017 · External reference
Construction of a genetic toggle switch in Escherichia coli
10.1038/35002131 · 2000 · External reference
Co-cultivation of microalgae and bacteria for optimal bioenergy feedstock production in wastewater by using response surface methodology
10.1038/s41598-024-70033-1 · 2024 · External reference
Experimental study of substrate limitation and light acclimation in cultures of the microalgae Scenedesmus obliquus—parameter identification and model predictive control
10.3390/pr8121551 · 2020 · External reference
Dynamic regulation of metabolic flux in engineered bacteria using a pathway-independent quorum-sensing circuit
10.1038/nbt.3796 · 2017 · External reference
A mini review: photobioreactors for large scale algal cultivation
10.1007/s11274-015-1892-4 · 2015 · External reference
Dynamic control in metabolic engineering: theories, tools, and applications
10.1016/j.ymben.2020.08.015 · 2021 · External reference
Model predictive control coupled with economic and environmental constraints for optimum algal production
10.1016/j.biortech.2017.11.047 · 2018 · External reference
Quantifying thermal extremes and biological variation to predict evolutionary responses to changing climate
10.1098/rstb.2016.0147 · 2017 · External reference
Improving photosynthesis and crop productivity by accelerating recovery from photoprotection
10.1126/science.aai8878 · 2016 · External reference
Epigenetic and genetic contributions to adaptation in Chlamydomonas
10.1093/molbev/msx166 · 2017 · External reference
Interplay between high-energy quenching and state transitions in Chlamydomonas reinhardtii: a single-cell approach
10.1111/nph.71001 · 2026 · External reference
Adaptive laboratory evolution for algal strain improvement: methodologies and applications
10.1016/j.algal.2020.102122 · 2021 · External reference
Adaptive laboratory evolution for increased temperature tolerance of the diatom Nitzschia inconspicua
10.1002/mbo3.1343 · 2023 · External reference
Plasticity across levels: relating epigenomic, transcriptomic, and phenotypic responses to osmotic stress in a halotolerant microalga
10.1111/mec.16542 · 2022 · External reference
Synthetic biology: engineering Escherichia coli to see light
10.1038/nature04405 · 2005 · External reference
Harnessing microalgae for bioproducts: innovations in synthetic biology
10.1007/s11274-025-04727-7 · 2025 · External reference
Physiological performance curves: when are they useful?
10.3389/fphys.2021.805102 · 2021 · External reference
Balancing cell growth and product synthesis for efficient microbial cell factories
10.1002/advs.202510649 · 2025 · External reference
Engineering Nannochloropsis oceanica for concurrent production of canthaxanthin and eicosapentaenoic acid
10.1016/j.biortech.2024.131525 · 2024 · External reference
Synthetic memory circuits for stable cell reprogramming in plants
10.1038/s41587-022-01383-2 · 2022 · External reference
Engineering microalgae: transition from empirical design to programmable cells
10.1080/07388551.2021.1917507 · 2021 · External reference
The Chlamydomonas CO2-concentrating mechanism and its potential for engineering photosynthesis in plants
10.1111/nph.14749 · 2018 · External reference
Mutations in the circadian cycle drive adaptive plasticity in cyanobacteria
10.1073/pnas.2506928122 · 2025 · External reference
Light-dependent single-cell heterogeneity in the chloroplast redox state regulates cell fate in a marine diatom
10.7554/elife.47732 · 2019 · External reference
Double-strand break-free and transgene-free genome editing in the microalga Nannochloropsis oceanica using removable vectors containing the CRISPR base editing system
10.1038/s41598-025-26657-y · 2025 · External reference
Recent advancements in microbial carbon dioxide fixation: metabolic engineering strategies
10.1039/d5gc03349g · 2026 · External reference
CRISPR–Cas ribonucleoprotein mediated homology-directed repair for efficient targeted genome editing in microalgae Nannochloropsis oceanica IMET1
10.1186/s13068-019-1401-3 · 2019 · External reference
Estimate of the spontaneous mutation rate in Chlamydomonas reinhardtii
10.1534/genetics.112.145078 · 2012 · External reference
An epigenetic gene silencing pathway selectively acting on transgenic DNA in the green alga Chlamydomonas
10.1038/s41467-020-19983-4 · 2020 · External reference
A critical review of genome editing and synthetic biology applications in metabolic engineering of microalgae and cyanobacteria
10.1002/biot.201900228 · 2020 · External reference
Genetic circuit design automation
10.1126/science.aac7341 · 2016 · External reference
Engineering cellular metabolism
10.1016/j.cell.2016.02.004 · 2016 · External reference
Robustness: linking strain design to viable bioprocesses
10.1016/j.tibtech.2022.01.004 · 2022 · External reference
Enhancing industrial microalgae production through economic model predictive control
10.1016/j.compchemeng.2026.109714 · 2026 · External reference
Real-time tracking of intracellular prenyl phosphate pools in the marine diatom Phaeodactylum tricornutum with a metabolite protein-based biosensor
10.1021/acssynbio.5c00231 · 2026 · External reference
An ancient light-harvesting protein is critical for the regulation of algal photosynthesis
10.1038/nature08587 · 2009 · External reference
Modulation of xanthophyll cycle impacts biomass productivity in the marine microalga Nannochloropsis
10.1073/pnas.2214119120 · 2023 · External reference
A blue-light photoreceptor mediates the feedback regulation of photosynthesis
10.1038/nature19358 · 2016 · External reference
Quality by design for biopharmaceuticals
10.1038/nbt0109-26 · 2009 · External reference
Engineered autonomous dynamic regulation of metabolic flux
10.1038/s44222-023-00140-7 · 2024 · External reference
Predicting population genetic change in an autocorrelated random environment: insights from a large automated experiment
10.1371/journal.pgen.1009611 · 2021 · External reference
A response surface methodology study for Chlorella vulgaris mixotrophic culture optimization
10.3390/microorganisms12020379 · 2024 · External reference
Synthetic addiction extends the productive lifetime of engineered Escherichia coli populations
10.1073/pnas.1718622115 · 2018 · External reference
Diatom pyrenoids are encased in a protein shell that enables efficient CO2 fixation
10.1016/j.cell.2024.09.013 · 2024 · External reference
Synthetic biology and metabolic engineering of microalgae for sustainable lipid and terpenoid production: an updated perspective
10.1111/pbi.70405 · 2026 · External reference
Kinetics of the xanthophyll cycle and its role in photoprotective memory and response
10.1038/s41467-023-42281-8 · 2023 · External reference
Genotype-by-environment interactions in beef and dairy cattle populations: a review of methodologies and perspectives on research and applications
10.1111/age.13483 · 2024 · External reference
Synthetic photorespiratory bypass increases crop yield
2019 · External reference
Central transcriptional regulator controls photosynthetic growth and carbon storage in response to high light
10.1038/s41467-024-49090-7 · 2024 · External reference
Bet hedging in a unicellular microalga
10.1038/s41467-024-46297-6 · 2024 · External reference
Acclimation of Chlamydomonas reinhardtii to extremely strong light
10.1007/s11120-020-00802-2 · 2021 · External reference
High-throughput Raman-activated cell sorting of microalgal genome-wide edited library revealed a regulatory pathway for carotenoid synthesis
10.1038/s41467-026-74304-5 · 2026 · External reference
Large-scale design of robust genetic circuits with multiple inputs and outputs for mammalian cells
10.1038/nbt.3805 · 2017 · External reference
Design of a dynamic sensor-regulator system for production of chemicals and fuels derived from fatty acids
10.1038/nbt.2149 · 2012 · External reference
Combining mechanistic and machine learning models for predictive engineering and optimization of tryptophan metabolism
10.1038/s41467-020-17910-1 · 2020 · External reference
Exploring a blue-light-sensing transcription factor to double the peak productivity of oil in Nannochloropsis oceanica
10.1038/s41467-022-29337-x · 2022 · External reference
Ultrafast energy quenching mechanism of LHCSR3-dependent photoprotection in Chlamydomonas
10.1038/s41467-024-48789-x · 2024 · External reference