References

Medicinal chemistry, pharmacology, and potential therapeutic benefits of cannabinoid CB2 receptor agonists

10.1021/acs.chemrev.5b00411 · 2016 · External reference

Neurochemical basis of cannabis addiction

10.1016/j.neuroscience.2011.02.035 · 2011 · External reference

The endocannabinoid system and heart disease: the role of cannabinoid receptor type 2

10.2174/1871529x18666180206161457 · 2018 · External reference

The CB2 receptor and its role as a regulator of inflammation

10.1007/s00018-016-2300-4 · 2016 · External reference

Protective role of neuronal and lymphoid cannabinoid CB2 receptors in neuropathic pain

10.7554/elife.55582 · 2020 · External reference

Cannabidiol ameliorates PTSD-like symptoms by inhibiting neuroinflammation through its action on CB2 receptors in the brain of male mice

10.1016/j.bbi.2024.05.016 · 2024 · External reference

Advances in the study of pharmacotherapy for addiction to naturally-derived psychoactive substances

2025 · External reference

Targeting cannabinoid type 2 receptors alters human tau levels in ex vivo brain slice cultures

10.1002/alz.093442 · 2024 · External reference

Developing the cannabinoid receptor 2 (CB2) pharmacopoeia: past, present, and future

10.1016/j.tips.2022.06.010 · 2022 · External reference

The development and therapeutic potential of classical and next-generation cannabinoid ligands

10.1016/j.phrs.2025.108022 · 2025 · External reference

Applying structure-based drug design approaches to allosteric modulators of GPCRs

10.1016/j.tips.2017.05.010 · 2017 · External reference

Biased allosteric modulation in GPCR drug discovery

10.1007/164_2025_771 · 2026 · External reference

Elucidating biased signaling in class a GPCRs

10.1016/j.tips.2025.10.008 · 2025 · External reference

Mechanism of β2AR regulation by an intracellular positive allosteric modulator

10.1126/science.aaw8981 · 2019 · External reference

Antidepressant effects and mechanisms of group II mGlu receptor-specific negative allosteric modulators

10.1016/j.neuron.2019.12.011 · 2020 · External reference

Structural basis for allosteric agonism of human α7 nicotinic acetylcholine receptors

10.1038/s41421-025-00788-y · 2025 · External reference

Rational design of neutral allosteric modulators of the CB1 receptor with improved receptor interactions and unique pharmacology

10.1016/j.bpj.2012.11.2278 · 2013 · External reference

Allosteric modulation of G protein-coupled receptors as a novel therapeutic strategy in neuropathic pain

10.1016/j.apsb.2023.07.020 · 2024 · External reference

Structural perspectives on biased allostery of GPCR Signaling

10.1007/164_2025_767 · 2026 · External reference

State-specific peptide design targeting G protein-coupled receptors

10.1021/acs.jcim.5c00884 · 2025 · External reference

Pepcan-12 (RVD-hemopressin) is a CB2 receptor positive allosteric modulator constitutively secreted by adrenals and in liver upon tissue damage

10.1038/s41598-017-09808-8 · 2017 · External reference

In silico prediction and validation of CB2 allosteric binding sites to aid the design of allosteric modulators

10.3390/molecules27020453 · 2022 · External reference

Design of Negative and Positive Allosteric Modulators of the cannabinoid CB2 receptor derived from the natural product cannabidiol

10.1021/acs.jmedchem.1c00561 · 2021 · External reference

Osteogenic growth peptide is a potent anti-inflammatory and bone preserving hormone via cannabinoid receptor type 2

10.7554/elife.65834 · 2022 · External reference

Identification of an unexplored dynamic allosteric site on the activation pathway of the vasopressin V2 receptor

10.1021/acs.jmedchem.5c01619 · 2025 · External reference

Improving protein-peptide docking results via pose-clustering and rescoring with a combined knowledge-based and MM-GBSA scoring function

10.1021/acs.jcim.0c00058 · 2020 · External reference

Quantifying conformational changes in GPCRs: glimpse of a common functional mechanism

10.1186/s12859-015-0567-3 · 2015 · External reference

Discovery and development of macrocyclic peptide modulators of the cannabinoid 2 receptor

10.1016/j.jbc.2024.107330 · 2024 · External reference

Advances in cannabinoid receptors pharmacology: from receptor structural insights to ligand discovery

10.1038/s41401-024-01472-9 · 2025 · External reference

Allosterism in the adenosine A2A and cannabinoid CB2 heteromer

10.1111/bph.16502 · 2025 · External reference

Cryo-EM structure of the human cannabinoid receptor CB2-Gi signaling complex

10.1016/j.cell.2020.01.007 · 2020 · External reference

Identification of a cannabinoid receptor 2 allosteric site using computational modeling and pharmacological analysis

10.1021/acsptsci.4c00547 · 2025 · External reference