Research graph
References from Pralatrexate injection combined with oral leucovorin for mucositis management in PTCL/CTCL treatment: a multicenter phase 2 trial. Local targets link to admitted publications; unresolved targets remain external evidence.
Unresolved reference
External reference
TCR sequencing facilitates diagnosis and identifies mature T cells as the cell of origin in CTCL
10.1126/scitranslmed.aaa9122 · 2015 · External reference
Peripheral T-cell lymphomas, unspecified (or not otherwise specified): a review
10.1002/hon.836 · 2008 · External reference
Pralatrexate in patients with relapsed or refractory peripheral T-cell lymphoma: results from the pivotal PROPEL study
10.1200/jco.2010.29.9024 · 2011 · External reference
Oral mucositis: the hidden side of cancer therapy
10.1186/s13046-020-01715-7 · 2020 · External reference
Efficacy of short oral leucovorin rescue (SOLR) in managing recurrent pralatrexate (Folotyn) induced mucositis (RPIM) despite dose reduction
10.1182/blood.v118.21.4745.4745 · 2011 · External reference
Preemptive leucovorin administration minimizes pralatrexate toxicity without sacrificing efficacy
10.3109/10428194.2013.779688 · 2013 · External reference
Effect of leucovorin administration on mucositis and skin reactions in patients with peripheral T-cell lymphoma or cutaneous T-cell lymphoma treated with pralatrexate
10.1080/10428194.2019.1612061 · 2019 · External reference
Toxic Effects
1979 · External reference
Pralatrexate (PDX) is synergistic with the proteasome inhibitor bortezomib in in vitro and in vivo models of T-cell lymphoid malignancies
10.1158/1078-0432.ccr-10-0671 · 2010 · External reference
Goldman ID the impact of 5-formyltetrahydrofolate on the anti-tumor activity of pralatrexate, as compared to methotrexate, in HeLa cells in vitro
10.1007/s00280-014-2441-9 · 2014 · External reference
Leucovorin rescue allows effective high- dose pralatrexate treatment and an increase in therapeutic index in mesothelioma xenografts
10.1007/s00280-014-2580-z · 2014 · External reference
Pralatrexate injection combined with CHOP for treatment of PTCL: results from the Fol-CHOP dose-finding phase 1 trial
10.1182/bloodadvances.2023011095 · 2024 · External reference
Impact of leucovorin on mucositis and skin reactions in patients with PTCL and CTCL treated with pralatrexate
10.1200/jco.2016.34.15_suppl.7558 · 2016 · External reference
