Research graph
References from A novel 3-way translocation involving ETV6::IL3 drives AML with eosinophilia. Local targets link to admitted publications; unresolved targets remain external evidence.
Eosinophilia in acute myeloid leukemia: overlooked and underexamined
10.1016/j.blre.2019.03.007 · 2019 · External reference
M4 acute myeloid leukemia: the role of eosinophilia and cytogenetics in treatment response and survival. The GIMEMA experience
10.3324/haematol.11889 · 2008 · External reference
Five years since the discovery of FIP1L1-PDGFRA: what we have learned about the fusion and other molecularly defined eosinophilias
10.1038/leu.2008.287 · 2008 · External reference
ETV6 fusion genes in hematological malignancies: a review
10.1016/j.leukres.2012.04.010 · 2012 · External reference
Characterization of leukemias with ETV6-ABL1 fusion
10.3324/haematol.2016.144345 · 2016 · External reference
Cardiovascular manifestations of hypereosinophilic syndromes
10.1016/j.iac.2007.07.001 · 2007 · External reference
IL-5 triggers a cooperative cytokine network that promotes eosinophil precursor maturation
10.4049/jimmunol.1400732 · 2014 · External reference
A critical role for IL-18 in transformation and maturation of naive eosinophils to pathogenic eosinophils
10.1016/j.jaci.2018.02.011 · 2018 · External reference
RUNX1 loss renders hematopoietic and leukemic cells dependent on IL-3 and sensitive to JAK inhibition
10.1172/jci167053 · 2023 · External reference
A novel IL3-ETV6 fusion in chronic eosinophilic leukemia not otherwise specified with t(5; 12) (q31; p13): a case report and literature review
2022 · External reference
Myeloid neoplasm with ETV6::ACSl6 fusion: landscape of molecular and clinical features
10.1080/16078454.2022.2117206 · 2022 · External reference
ETV6::ACSL6 translocation-driven super-enhancer activation leads to eosinophilia in acute lymphoblastic leukemia through IL-3 overexpression
2024 · External reference
Super-enhancers in the control of cell identity and disease
10.1016/j.cell.2013.09.053 · 2013 · External reference
Super-enhancers and the super-enhancer reader BRD4: tumorigenic factors and therapeutic targets
10.1038/s41420-023-01775-6 · 2023 · External reference
Activation of the interleukin-3 gene by chromosome translocation in acute lymphocytic leukemia with eosinophilia
10.1182/blood.v76.2.285.285 · 1990 · External reference
Clinical utility of next generation sequencing to detect IGH/IL3 rearrangements [t(5;14)(q31.1;q32.1)] in B-lymphoblastic leukemia/lymphoma
10.1016/j.anndiagpath.2021.151761 · 2021 · External reference
World Health Organization-defined eosinophilic disorders: 2014 update on diagnosis, risk stratification, and management
10.1002/ajh.23664 · 2014 · External reference
Treatment of patients with the hypereosinophilic syndrome with mepolizumab
10.1056/nejmoa070812 · 2008 · External reference
Jak1 integrates cytokine sensing to regulate hematopoietic stem cell function and stress hematopoiesis
10.1016/j.stem.2017.08.011 · 2017 · External reference
