Research graph
References from Thymic peptides in immune reconstitution and clinical outcome after allogeneic hematopoietic cell transplantation. Local targets link to admitted publications; unresolved targets remain external evidence.
Immune reconstitution following stem cell transplantation
10.1182/asheducation-2015.1.215 · 2015 · External reference
CD4+ T-cell reconstitution predicts survival outcomes after acute graft-versus-host-disease: a dual-center validation
10.1182/blood.2020007905 · 2021 · External reference
Immune reconstitution after allogeneic hematopoietic stem cell transplantation: time to T up the thymus
10.4049/jimmunol.1601100 · 2017 · External reference
T cell regeneration after immunological injury
10.1038/s41577-020-00457-z · 2021 · External reference
Resetting the T cell compartment in autoimmune diseases with autologous hematopoietic stem cell transplantation: an update
10.3389/fimmu.2018.00767 · 2018 · External reference
The thymus road to a T cell: migration, selection, and atrophy
2024 · External reference
Cutting edge: homeostatic proliferation of peripheral T lymphocytes is regulated by clonal competition1
10.4049/jimmunol.170.2.672 · 2003 · External reference
Thymosin alpha 1: a comprehensive review of the literature
10.5501/wjv.v9.i5.67 · 2020 · External reference
Precursors of thymic peptides as stress sensors
10.1080/14712598.2020.1800636 · 2020 · External reference
Signaling pathways leading to the activation of IKK and MAPK by thymosin α1
10.1196/annals.1415.025 · 2007 · External reference
Thymosin alpha-1 treatment in chronic hepatitis B
10.1517/14712598.2015.1007948 · 2015 · External reference
Immunotherapy for hepatitis B in the direct acting antiviral era: reevaluating the thymosin α1 efficacy trials in the light of a combination therapy approach
10.1111/jvh.12807 · 2018 · External reference
The efficacy of thymosin in the treatment of chronic hepatitis B virus infection: a meta-analysis
10.1046/j.1365-2036.2001.01135.x · 2001 · External reference
Thymosin alpha 1 and HIV-1: recent advances and future perspectives
10.2217/fmb-2016-0125 · 2017 · External reference
Thymalfasin in the treatment of hepatitis B and C
10.1111/j.1749-6632.2010.05487.x · 2010 · External reference
Thymosin alpha 1 treatment for patients with sepsis
10.1080/14712598.2018.1484104 · 2018 · External reference
Thymosin alpha 1 restores the immune homeostasis in lymphocytes during post-acute sequelae of SARS-CoV-2 infection
10.1016/j.intimp.2023.110055 · 2023 · External reference
Thymosin α1 and its role in viral infectious diseases: the mechanism and clinical application
10.3390/molecules28083539 · 2023 · External reference
Jack of all trades: thymosin α1 and its pleiotropy
10.1111/j.1749-6632.2012.06716.x · 2012 · External reference
The role of Tα1 on the infective patients after hematopoietic stem cell transplantation
10.1007/s12185-012-1208-5 · 2013 · External reference
Augmentation of influenza antibody response in elderly men by thymosin alpha one. A double-blind placebo-controlled clinical study
10.1111/j.1532-5415.1989.tb01561.x · 1989 · External reference
Thymosin-alpha 1 (Zadaxin) enhances the immunogenicity of an adjuvated pandemic H1N1v influenza vaccine (Focetria) in hemodialyzed patients: a pilot study
10.1016/j.vaccine.2011.12.014 · 2012 · External reference
Higher plasma levels of thymosin-α1 are associated with a lower waning of humoral response after COVID-19 vaccination: an eight months follow-up study in a nursing home
10.1186/s12979-023-00334-y · 2023 · External reference
Thymosin alfa 1 administration improves immune reconstitution and decreases infection-related mortality after HLA-matched sibling T cell-depleted stem cell transplantation
10.1182/blood.v118.21.1013.1013 · 2011 · External reference
Thymosin alpha 1 effects, in vitro, on lymphokine-activated killer cells from patients with primary immunodeficiencies: preliminary results
10.1016/0192-0561(94)90081-7 · 1994 · External reference
Epigenetic therapy promotes the ratio of Th1/Th17 lineage to reverse immune evasion and treat leukemia relapse post-allogeneic stem cell transplantation in non-APL AML patients
10.3389/fmolb.2020.595395 · 2021 · External reference
Serum thymosin alpha 1 levels in normal and pathological conditions
10.1080/14712598.2018.1474197 · 2018 · External reference
A reappraisal of thymosin alpha1 in cancer therapy
10.3389/fonc.2019.00873 · 2019 · External reference
Thymosin alpha 1 reduces the mortality of severe coronavirus disease 2019 by restoration of lymphocytopenia and reversion of exhausted T cells
10.1093/cid/ciaa630 · 2020 · External reference
Thymomodulin: biological properties and clinical applications
10.1007/bf02985217 · 1989 · External reference
Thyroid dysfunctions in adult patients after allogeneic hematopoietic stem cell transplantation
10.1111/ctr.14049 · 2020 · External reference
Restorative effect of thymomodulin and zinc on interferon-gamma production in aged mice
10.1111/j.1749-6632.1992.tb27461.x · 1992 · External reference
The effect of a calf thymus acid lysate on bone marrow cell growth in vitro
10.3109/08923978809006453 · 1988 · External reference
Thymomodulin stimulates phagocytosis in vitro by rat macrophages and human polymorphonuclear cells
10.1080/1120009x.1993.11739251 · 1993 · External reference
A double-blind clinical trial for the evaluation of the therapeutical effectiveness of a calf thymus derivative (Thymomodulin) in children with recurrent respiratory infections
1986 · External reference
Thymomodulin increases HLA-DR expression by macrophages but not T-lymphocyte proliferation in autologous mixed leucocyte reaction
10.1183/09031936.93.06010102 · 1993 · External reference
Immunomodulatory role of thymulin in lung diseases
10.1517/14728220903512991 · 2010 · External reference
Thymulin treatment attenuates inflammatory pain by modulating spinal cellular and molecular signaling pathways
10.1016/j.intimp.2019.02.042 · 2019 · External reference
Thymulin and peroxiredoxin 6 have protective effects against streptozotocin-induced type 1 diabetes in mice
10.1177/20587384211005645 · 2021 · External reference
The thymus-neuroendocrine axis: physiology, molecular biology, and therapeutic potential of the thymic peptide thymulin
10.1111/j.1749-6632.2008.03964.x · 2009 · External reference
Thymulin-based gene therapy and pituitary function in animal models of aging
10.1159/000329495 · 2011 · External reference
Cytokine-mediated or direct effects of thymulin on the nervous system as assessed by pain-related behavior
10.1159/000026362 · 1999 · External reference
Targeting inflammatory components in neuropathic pain: the analgesic effect of thymulin related peptide
10.1016/j.neulet.2018.11.041 · 2019 · External reference
Thymulin and its role in immunomodulation
10.1016/0896-8411(92)90152-g · 1992 · External reference
Neonatal thymulin gene therapy in nude mice: effects on the morphology of the pituitary corticotrope population
2011 · External reference
The thymulin-lactotropic axis in rodents: thymectomy, immunoneutralization and gene transfer studies
10.1159/000346477 · 2013 · External reference
The emerging role of thymopoietin-antisense RNA 1 as long noncoding RNA in the pathogenesis of human cancers
10.1089/dna.2021.0024 · 2021 · External reference
Thymopoietin beta and gamma isoforms as a potential diagnostic molecular marker for breast cancer: preliminary data
10.1007/s12253-015-9907-x · 2015 · External reference
Immunoregulation by thymopoietin
10.1002/jss.400140312 · 1980 · External reference
Immunomodulation with thymopentin: in vitro studies
10.1007/bf02985219 · 1989 · External reference
Thymopoietin pentapeptide treatment of primary immunodeficiencies
10.1016/s0140-6736(83)92810-6 · 1983 · External reference
Clinicopathologic and prognostic significance of thymopoietin-α overexpression in gastric cancer
10.7150/jca.30738 · 2019 · External reference
Depletion of thymopoietin inhibits proliferation and induces cell cycle arrest/apoptosis in glioblastoma cells
10.1186/s12957-016-1018-y · 2016 · External reference
Thymopoietin enhances the allogeneic response and cyclic GMP levels of mouse peripheral, thymus-derived lymphocytes1
10.4049/jimmunol.120.5.1594 · 1978 · External reference
Immunopotentiating and immunotherapeutic effects of thymic hormones and factors with special emphasis on thymic humoral factor THF-gamma2
1999 · External reference
Degradation of thymic humoral factor γ2 in human, rat and mouse blood: an experimental and theoretical study
10.1016/j.bbapap.2020.140467 · 2020 · External reference
Treatment of chronic hepatitis D with thymus-derived polypeptide thymic humoral factor-gamma 2: a pilot study
10.1016/s1590-8658(02)80149-9 · 2002 · External reference
Prospects of AIDS therapy by thymic humoral factor, a thymic hormone
1990 · External reference
Thymic humoral factor effect on intracellular lymphocyte cAMP in patients with ankylosing spondylitis
1982 · External reference
Cellular immunity in patients with acquired immunodeficiency syndrome (AIDS) in Israel: effects of THF, a thymic hormone in vitro
1986 · External reference
Cell mediated immunity and effects of “thymic humoral factor” in 15 patients with SSPE
10.1016/s0387-7604(83)80006-0 · 1983 · External reference
The in vitro effect of thymic humoral factor and levamisole on peripheral blood lymphocytes in systemic lupus erythematosus patients
1978 · External reference
Thymic humoral factor, THF-gamma 2, enhances immunotherapy of murine cytomegalovirus (MCMV) infection by both CD4+ and CD8+ immune T cells
10.1016/0165-2478(93)90160-4 · 1993 · External reference
Protective effect of thymic humoral factor on porcine serum-induced hepatic fibrosis and liver damage in Wistar rats
10.1016/s1665-2681(19)31523-6 · 2011 · External reference
THF, a thymic hormone, promotes interleukin-2 production in intact and thymus-deprived mice
1984 · External reference
Thymic humoral factor-gamma 2 augments immune cell response and exerts antitumor activity in murine model systems
2000 · External reference
Thymic humoral factor-gamma 2 (THF-gamma 2) immunotherapy reduces the metastatic load and restores immunocompetence in 3LL tumor-bearing mice receiving anticancer chemotherapy
10.3109/08923979609052733 · 1996 · External reference
Thymosin alpha 1 and thymosin beta 4 in serum: comparison of normal, cord, homosexual and AIDS serum
10.1016/0192-0561(86)90001-9 · 1986 · External reference
Localization of thymosin alpha 1 production to thymus medullary epithelial cells by use of monoclonal antibodies
10.1089/hyb.1987.6.47 · 1987 · External reference
Serum levels of immunoreactive thymosin alpha 1 and thymosin beta 4 in large cohorts of healthy adults
1992 · External reference
Comprehensive review of the safety and efficacy of thymosin alpha 1 in human clinical trials
2024 · External reference
A calf thymus acid lysate improves clinical symptoms and T-cell defects in the early stages of HIV infection: second report
10.1016/0277-5379(87)90059-9 · 1987 · External reference
Thymomodulin increases the depressed production of superoxide anion by alveolar macrophages in patients with chronic bronchitis
1989 · External reference
Thyroid function modulates thymic endocrine activity
10.1210/jcem-62-3-474 · 1986 · External reference
The thymus is a common target in malnutrition and infection
10.1017/s0007114507832880 · 2007 · External reference
Thymus, undernutrition, and infection: approaching cellular and molecular interactions
10.3389/fnut.2022.948488 · 2022 · External reference
Thymulin (Zn-facteur thymique serique) activity in anorexia nervosa patients
10.1093/ajcn/42.2.275 · 1985 · External reference
Evidence that appearance of thymulin in plasma follows lymphoid chimerism and precedes development of immunity in patients with lethal combined immunodeficiency transplanted with T cell-depleted haploidentical marrow
1990 · External reference
Serum thymulin in human zinc deficiency
10.1172/jci113717 · 1988 · External reference
Activation of the zinc-sensing receptor GPR39 promotes T-cell reconstitution after hematopoietic cell transplant in mice
10.1182/blood.2021013950 · 2022 · External reference
Bioassay determinations of thymopoietin and thymic hormone levels in human plasma
10.1073/pnas.74.6.2541 · 1977 · External reference
Immunomodulatory effect and acetylcholine receptor binding of a thymopeptide (Tp4) on human peripheral blood lymphocytes
10.1177/039463209100400101 · 1991 · External reference
Thymopoietin radioreceptor assay utilizing lectin-purified glycoprotein from a biologically responsive T cell line
10.1016/0003-9861(84)90338-2 · 1984 · External reference
Thymopoietin pentapeptide (TP-5) improves clinical parameters and lymphocyte subpopulations in atopic dermatitis
10.1016/s0190-9622(83)70042-3 · 1983 · External reference
Attempted treatment of acquired immunodeficiency syndrome (AIDS) with thymic humoral factor
1984 · External reference
Clinical experience of thymic regeneration with thymus extracts, thymic peptides and stem cells in general medicine, oncology and anti-aging medicine: a review
2023 · External reference
IL-2-based approaches to Treg enhancement
10.1093/cei/uxac105 · 2023 · External reference
Biology of interleukin-10
10.1016/j.cytogfr.2010.09.002 · 2010 · External reference
TNFR2 signaling modulates immunity after allogeneic hematopoietic cell transplantation
10.1016/j.cytogfr.2019.05.001 · 2019 · External reference
Graft-versus-solid-tumor effect: from hematopoietic stem cell transplantation to adoptive cell therapies
10.1093/stmcls/sxac021 · 2022 · External reference
Role of natural killer cell alloreactivity in HLA-mismatched hematopoietic stem cell transplantation
10.1182/blood.v94.1.333.413a31_333_339 · 1999 · External reference
Inflammatory cytokine inhibition with combination daclizumab and infliximab for steroid-refractory acute GVHD
10.1038/bmt.2010.117 · 2011 · External reference
Tumor necrosis factor-alpha blockade for the treatment of acute GVHD
10.1182/blood-2003-12-4241 · 2004 · External reference
IFN-γ promotes graft-versus-leukemia effects without directly interacting with leukemia cells in mice after allogeneic hematopoietic cell transplantation
10.1182/blood-2010-05-283887 · 2011 · External reference
Paradoxical effects of IFN-gamma in graft-versus-host disease reflect promotion of lymphohematopoietic graft-versus-host reactions and inhibition of epithelial tissue injury
10.1182/blood-2008-07-168419 · 2009 · External reference
Novel strategies for improving hematopoietic reconstruction after allogeneic hematopoietic stem cell transplantation or intensive chemotherapy
10.1080/14712598.2017.1269167 · 2017 · External reference
Use of glycosylated recombinant human G-CSF (lenograstim) during and/or after induction chemotherapy in patients 61 years of age and older with acute myeloid leukemia: final results of AML-13, a randomized phase-3 study
10.1182/blood-2004-09-3728 · 2005 · External reference
Colony-stimulating factors for prevention and treatment of infectious complications in patients with acute myelogenous leukemia
10.1002/14651858.cd008238.pub3 · 2012 · External reference