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References from Genomic landscape and clonal architecture in pediatric myeloid neoplasms with chromosome 7 deletions. Local targets link to admitted publications; unresolved targets remain external evidence.
Monosomy 7 in pediatric myelodysplastic syndromes
10.1016/j.hoc.2018.04.007 · 2018 · External reference
Juvenile myelomonocytic leukemia-a comprehensive review and recent advances in management
2021 · External reference
Cytogenetic and molecular delineation of a region of chromosome 7 commonly deleted in malignant myeloid diseases
1996 · External reference
Functional evidence implicating chromosome 7q22 haploinsufficiency in myelodysplastic syndrome pathogenesis
10.7554/elife.07839 · 2015 · External reference
The enigma of monosomy 7
10.1182/blood-2017-12-822262 · 2018 · External reference
The significance of CUX1 and chromosome 7 in myeloid malignancies
10.1097/moh.0000000000000699 · 2022 · External reference
Genomics of deletion 7 and 7q in myeloid neoplasm: from pathogenic culprits to potential synthetic lethal therapeutic targets
10.1038/s41375-023-02003-x · 2023 · External reference
Genomic characterization of AML with aberrations of chromosome 7: a multinational cohort of 519 patients
10.1186/s13045-024-01590-1 · 2024 · External reference
Genomes for kids: the scope of pathogenic mutations in pediatric cancer revealed by comprehensive DNA and RNA sequencing
10.1158/2159-8290.cd-20-1631 · 2021 · External reference
The genomic landscape of pediatric myelodysplastic syndromes
10.1038/s41467-017-01590-5 · 2017 · External reference
The acquisition of molecular drivers in pediatric therapy-related myeloid neoplasms
10.1038/s41467-021-21255-8 · 2021 · External reference
Integrated genomic analysis identifies UBTF tandem duplications as a recurrent lesion in pediatric acute myeloid leukemia
10.1158/2643-3230.bcd-21-0160 · 2022 · External reference
A new genomic framework to categorize pediatric acute myeloid leukemia
10.1038/s41588-023-01640-3 · 2024 · External reference
SJPedPanel: a pan-cancer gene panel for childhood malignancies to enhance cancer monitoring and early detection
10.1158/1078-0432.ccr-24-1063 · 2024 · External reference
-7/7q- syndrome in myeloid-lineage hematopoietic malignancies: attempts to understand this complex disease entity
10.1038/onc.2014.196 · 2015 · External reference
CRISPR screening in human hematopoietic stem and progenitor cells reveals an enrichment for tumor suppressor genes within chromosome 7 commonly deleted regions
10.1038/s41375-021-01491-z · 2022 · External reference
Recurrent genetic defects on chromosome 7q in myeloid neoplasms
10.1038/leu.2014.25 · 2014 · External reference
Loss of heterozygosity in 7q myeloid disorders: clinical associations and genomic pathogenesis
10.1182/blood-2011-12-397620 · 2012 · External reference
Clinical evolution, genetic landscape and trajectories of clonal hematopoiesis in SAMD9/SAMD9L syndromes [published correction appears in Nat Med. 2021;27(12):2248]
10.1038/s41591-021-01511-6 · 2021 · External reference
Germline SAMD9 and SAMD9L mutations are associated with extensive genetic evolution and diverse hematologic outcomes
10.1172/jci.insight.121086 · 2018 · External reference
EVI1-rearranged acute myeloid leukemias are characterized by distinct molecular alterations
10.1182/blood-2014-07-591529 · 2015 · External reference
The genomic landscape of juvenile myelomonocytic leukemia [published correction appears in Nat Genet. 2015;47(11):1333, Nat Genet. 2016;48(1):101
10.1038/ng.3400 · 2015 · External reference
Juvenile myelomonocytic leukemia displays mutations in components of the RAS pathway and the PRC2 network
10.1038/ng.3420 · 2015 · External reference
Heterogeneous disease-propagating stem cells in juvenile myelomonocytic leukemia
10.1084/jem.20180853 · 2021 · External reference
The molecular landscape of pediatric acute myeloid leukemia reveals recurrent structural alterations and age-specific mutational interactions
10.1038/nm.4439 · 2018 · External reference
5G2 mutant mice model loss of a commonly deleted segment of chromosome 7q22 in myeloid malignancies
10.1038/s41375-024-02205-x · 2024 · External reference
Gene dosage effect of CUX1 in a murine model disrupts HSC homeostasis and controls the severity and mortality of MDS
10.1182/blood-2017-10-810028 · 2018 · External reference
High EVI1 expression predicts outcome in younger adult patients with acute myeloid leukemia and is associated with distinct cytogenetic abnormalities
10.1200/jco.2009.26.0646 · 2010 · External reference
Oncogene EVI1 drives acute myeloid leukemia via a targetable interaction with CTBP2
10.1126/sciadv.adk9076 · 2024 · External reference
EVI1 is critical for the pathogenesis of a subset of MLL-AF9-rearranged AMLs
10.1182/blood-2011-11-393827 · 2012 · External reference
Single-cell RNA-seq reveals a distinct transcriptome signature of aneuploid hematopoietic cells
10.1182/blood-2017-08-803353 · 2017 · External reference
Mutant Samd9l expression impairs hematopoiesis and induces bone marrow failure in mice
10.1172/jci158869 · 2022 · External reference
