Contact and support
Need help, have a question, or want to contact the ResearchHub team?
© 2026 ResearchHub. Built for responsible scholarly connection.
Research graph
References from From peripheral to central (Neuro)degeneration: Is heart-kidney a new axial paradigm for Parkinson’s disease?. Local targets link to admitted publications; unresolved targets remain external evidence.
Role of brain renin angiotensin system in neurodegeneration: an update
10.1016/j.sjbs.2020.01.026 · 2020 · External reference
Non-coding RNAs in the brain-heart axis
2020 · External reference
Indoxyl sulfate affects glial function increasing oxidative stress and neuroinflammation in chronic kidney disease: interaction between astrocytes and microglia
2017 · External reference
Does Parkinson’s disease increase the risk of cardiovascular events? A systematic review and meta-analysis
10.1111/ene.14076 · 2020 · External reference
The renin-angiotensin-aldosterone system and its suppression
10.1111/jvim.15454 · 2019 · External reference
The inflammatory reflex - introduction
10.1111/j.1365-2796.2004.01440.x · 2005 · External reference
10.1242/jcs.180737
10.1242/jcs.180737 · External reference
Gliotransmitters travel in time and space
10.1016/j.neuron.2014.02.007 · 2014 · External reference
The impact of uremic toxins on cerebrovascular and cognitive disorders
10.3390/toxins10070303 · 2018 · External reference
Augustine 03NRN Local Ca Review
10.1016/s0896-6273(03)00639-1 · 2003 · External reference
Effect of chronic kidney disease on excessive daytime sleepiness in Parkinson disease
10.1111/j.1468-1331.2011.03391.x · 2011 · External reference
Incident Parkinson’s disease in kidney transplantation recipients: a nationwide population-based cohort study in Korea
10.1038/s41598-021-90130-9 · 2021 · External reference
The central autonomic network: functional organization, dysfunction, and perspective
10.1016/s0025-6196(12)62272-1 · 1993 · External reference
Prodromal Parkinson disease subtypes — key to understanding heterogeneity
10.1038/s41582-021-00486-9 · 2021 · External reference
10.1016/bs.pmbts.2020.01.008
10.1016/bs.pmbts.2020.01.008 · External reference
Calcium phosphate metabolism and cardiovascular disease in patients with chronic kidney disease
10.1046/j.1525-139x.2003.160301.x · 2003 · External reference
Parkinson’s disease
10.1016/s0140-6736(21)00218-x · 2021 · External reference
Uremic toxins and the brain in chronic kidney disease
10.1007/s40620-024-01929-4 · 2024 · External reference
10.1016/s0197-4580(02)00065-9
10.1016/s0197-4580(02)00065-9 · External reference
Idiopathic Parkinson’s disease: possible routes by which vulnerable neuronal types may be subject to neuroinvasion by an unknown pathogen
10.1007/s00702-002-0808-2 · 2003 · External reference
乳鼠心肌提取 HHS public access
2019 · External reference
Dopamine outside the brain: the eye, cardiovascular system and endocrine pancreas
10.1016/j.pharmthera.2019.07.003 · 2019 · External reference
Pressor responses to brain dopaminergic stimulation
10.1111/j.1440-1681.1997.tb02129.x · 1997 · External reference
Unresolved reference
2016 · External reference
10.1016/b978-0-444-53491-0.00005-5
10.1016/b978-0-444-53491-0.00005-5 · External reference
Cellular Calcium Signaling in the Aging Brain
10.1016/j.jchemneu.2017.11.008 · 2019 · External reference
Rejuvenation” protects neurons in mouse models of Parkinson’s disease
10.1038/nature05865 · 2007 · External reference
Renal dopaminergic system: pathophysiological implications and clinical perspectives
10.5527/wjn.v4.i2.196 · 2015 · External reference
Calcium signaling
10.1016/j.cell.2007.11.028 · 2007 · External reference
Brain renin–angiotensin system at the intersect of physical and cognitive frailty
2020 · External reference
Environmental factors in cardiovascular disease
10.1038/nrcardio.2015.152 · 2015 · External reference
Cardiac changes in Parkinson’s disease: lessons from clinical and experimental evidence
10.3390/ijms222413488 · 2021 · External reference
Central autonomic network functional connectivity: correlation with baroreflex function and cardiovascular variability in older adults
10.1007/s00429-020-02075-w · 2020 · External reference
The therapeutic potential of dopamine modulators on the cardiovascular and renal systems
10.1517/13543784.11.5.631 · 2002 · External reference
The control of diastolic calcium in the heart: basic mechanisms and functional implications
10.1161/circresaha.119.315891 · 2020 · External reference
Calcium in the heart: from physiology to disease
10.1113/expphysiol.2013.077305 · 2014 · External reference
Calcium channel blockers
10.1111/j.1751-7176.2011.00513.x · 2011 · External reference
Calcium release from the sarcoplasmic reticulum
10.1152/physrev.1977.57.1.71 · 1977 · External reference
Hypocalcemia, morbidity, and mortality in end-stage renal disease
10.1159/000169030 · 1996 · External reference
The “Parkinsonian Heart”: from novel vistas to advanced therapeutic approaches in Parkinsons disease
10.2174/092986707782023631 · 2007 · External reference
Calcium channel blockers: differences between subclasses
2007 · External reference
New insight in cardiorenal syndrome: from biomarkers to therapy
10.3390/ijms24065089 · 2023 · External reference
The clinical heterogeneity of Parkinson’s disease and its therapeutic implications
10.1111/ejn.14094 · 2019 · External reference
Effects of levodopa therapy on global left ventricular systolic function in patients with Parkinson disease
10.1007/s00508-016-1026-5 · 2016 · External reference
Robust pacemaking in substantia Nigra dopaminergic neurons
10.1523/jneurosci.2519-09.2009 · 2009 · External reference
Neurologic conditions and disorders of uremic syndrome of chronic kidney disease: presentations, causes, and treatment strategies
10.1080/17512433.2019.1555468 · 2019 · External reference
Randomised study of effect of ibopamine on survival in patients with advanced severe heart failure. second prospective randomised study of ibopamine on mortality and efficacy (PRIME II) investigators
10.1016/s0140-6736(96)10488-8 · 1997 · External reference
Calcium transport in the kidney and disease processes
2022 · External reference
The role of inflammation in cardiovascular disease
10.3390/ijms232112906 · 2022 · External reference
Dopamine in critically Ill patients with cardiac dysfunction: a systematic review with meta-analysis and trial sequential analysis
10.1111/aas.13294 · 2019 · External reference
Calcium balance in chronic kidney disease
10.1007/s11914-017-0368-x · 2017 · External reference
Association between Parkinson’s disease and atrial fibrillation: a population-based study
2019 · External reference
Hypertension and diagnosis of Parkinson’s disease: a meta-analysis of cohort studies
2018 · External reference
Amlodipine improves spinal cord injury repair by inhibiting motoneuronal apoptosis through autophagy upregulation
10.1097/brs.0000000000004310 · 2022 · External reference
Heart-brain synchronization breakdown in Parkinson’s disease
2022 · External reference
Within the brain: the renin angiotensin system
10.3390/ijms19030876 · 2018 · External reference
Cardiovascular dysautonomia in Parkinson disease: from pathophysiology to pathogenesis
10.1016/j.nbd.2011.10.025 · 2012 · External reference
Physiological phenotype and vulnerability in Parkinson’s disease
2012 · External reference
Cardiovascular disease in chronic kidney disease: pathophysiological insights and therapeutic options
10.1161/circulationaha.120.050686 · 2021 · External reference
Lower serum calcium is independently associated with CKD progression
10.1038/s41598-018-23500-5 · 2018 · External reference
Cardiorenal syndrome: long road between kidney and heart
10.1007/s10741-022-10218-w · 2022 · External reference
Parkinson’s disease
10.1016/s0140-6736(14)61393-3 · 2015 · External reference
Permeabilization of lipid bilayers is a common conformation-dependent activity of soluble amyloid oligomers in protein misfolding diseases
10.1074/jbc.c400260200 · 2004 · External reference
Inflammation and stroke risk: a new target for prevention
10.1161/strokeaha.121.034388 · 2021 · External reference
Association between Parkinson’s disease and cardiovascular disease mortality: a prospective population-based study from NHANES
10.1186/s12944-024-02200-2 · 2024 · External reference
LRRK2 kinase plays a critical role in manganese-induced inflammation and apoptosis in microglia
10.1371/journal.pone.0210248 · 2019 · External reference
Mid- and late-life chronic kidney disease is associated with Parkinson’s disease, not with an increased risk of Alzheimer’s disease
10.3390/jpm14060597 · 2024 · External reference
Association between heart rate variability and striatal dopamine depletion in Parkinson’s Disease
10.1007/s00702-021-02418-9 · 2021 · External reference
Genetics in CHronic Kidney Disease: Conclusions from A Kidney Disease: Improving global outcomes (KDIGO) controversies conference
10.1016/j.kint.2022.03.019 · 2022 · External reference
Autophagy in cardiovascular biology
10.1172/jci73943 · 2015 · External reference
The links between cardiovascular diseases and Alzheimer’s disease
10.2174/1570159x18666200729093724 · 2020 · External reference
Chronic kidney disease is more prevalent among women but more men than women are under nephrological care: analysis from six outpatient clinics in Austria 2019
10.1007/s00508-022-02074-3 · 2023 · External reference
Chronic kidney disease and neurological disorders: are uraemic toxins the missing piece of the Puzzle?
10.1093/ndt/gfab223 · 2021 · External reference
Low serum calcium is associated with poor renal outcomes in chronic kidney disease stages 3-4 patients
10.1186/1471-2369-15-183 · 2014 · External reference
Brain renin–angiotensin system as novel and potential therapeutic target for Alzheimer’s disease
10.3390/ijms221810139 · 2021 · External reference
Mitochondrial calcium imbalance in Parkinson’s disease
10.1016/j.neulet.2017.08.044 · 2018 · External reference
Chronic kidney disease in the elderly: evaluation and management
10.2217/cpr.14.46 · 2014 · External reference
Glia, sympathetic activity and cardiovascular disease
10.1113/ep085713 · 2016 · External reference
Dihydropyridine calcium channel blockers and the progression of parkinsonism
10.1002/ana.22616 · 2012 · External reference
Ibopamine and survival in severe congestive heart failure: PRIME II (Multiple Letters) [16]
10.1016/s0140-6736(05)61857-0 · 1997 · External reference
Effect of felodipine on myocardial and renal injury induced by aldosterone-high salt hypertension in uninephrectomized rats
10.1590/s0100-879x2010007500037 · 2010 · External reference
Alpha-synuclein in peripheral tissues in Parkinson’s disease
10.1021/acschemneuro.8b00383 · 2019 · External reference
Linking chronic kidney disease and Parkinson’s disease: a literature review
10.1007/s11011-020-00623-1 · 2021 · External reference
Cardiovascular alterations and structural changes in the setting of chronic kidney disease: a review of cardiorenal syndrome type 4
10.1007/s42399-022-01347-2 · 2022 · External reference
CK-dmineral and bone disorder: core curriculum 2011
10.1053/j.ajkd.2011.08.009 · 2011 · External reference
Parkinson’s disease proteins: novel mitochondrial targets for cardioprotection
10.1016/j.pharmthera.2015.10.005 · 2015 · External reference
Takotsubo cardiomyopathy induced by dopamine infusion after carotid artery stenting
10.1016/j.ijcard.2015.12.023 · 2016 · External reference
Chronic renal dysfunction, proteinuria, and risk of Parkinson’s disease in the elderly
10.1002/mds.27704 · 2019 · External reference
Autophagy in Parkinson’s disease
10.3390/biom13101435 · 2023 · External reference
Role of dopamine in the heart in health and disease
10.3390/ijms24055042 · 2023 · External reference
The role of autophagy in the heart
10.1038/cdd.2008.163 · 2009 · External reference
Cardiovascular effects of levodopa in Parkinson’s disease
10.1016/j.parkreldis.2014.04.007 · 2014 · External reference
Calcium channel blocker in patients with chronic kidney disease
10.1007/s10157-021-02153-1 · 2022 · External reference
Olfactory dysfunction and cardiovascular dysautonomia in Parkinson’s disease
10.1007/s00415-009-5447-1 · 2010 · External reference
Renal nerves and long-term control of arterial pressure
10.1002/cphy.c150047 · 2017 · External reference
Targeting serum calcium in chronic kidney disease and end-stage renal disease: is normal too high?
10.1016/j.kint.2015.10.001 · 2016 · External reference
Serum levels of phosphorus, parathyroid hormone, and calcium and risks of death in individuals with chronic kidney disease
10.1001/jama.2011.308 · 2011 · External reference
Calcium signaling and molecular mechanisms underlying neurodegenerative diseases
10.1016/j.ceca.2017.06.008 · 2018 · External reference
Pathophysiology of Takotsubo Syndrome
10.1161/circulationaha.116.027121 · 2017 · External reference
Association between kidney function and Parkinson’s disease risk: a prospective study from the UK biobank
10.1186/s12889-024-19709-x · 2024 · External reference
The emerging role of metabolism in brain-heart axis: new challenge for the therapy and prevention of Alzheimer Disease: may thioredoxin interacting protein (Txnip) play a role?
10.3390/biom11111652 · 2021 · External reference
Structural and functional alterations of the heart in Parkinson’s disease
10.1080/01616412.2017.1390933 · 2018 · External reference
Cardiorenal syndrome: an updated classification based on clinical hallmarks
10.3390/jcm11102896 · 2022 · External reference
Roles of subthreshold calcium current and sodium current in spontaneous firing of mouse midbrain dopamine neurons
10.1523/jneurosci.4341-06.2007 · 2007 · External reference
The role of the renal dopaminergic system and oxidative stress in the pathogenesis of hypertension
10.3390/biomedicines9020139 · 2021 · External reference
From cardiorenal syndromes to cardionephrology: a reflection by nephrologists on renocardiac syndromes
10.1093/ckj/sfac113 · 2023 · External reference
Estimated glomerular filtration rate is a biomarker of cognitive impairment in Parkinson’s disease
2023 · External reference
CKD progression risk and subsequent cause of death: a population-based cohort study
10.1016/j.xkme.2023.100604 · 2023 · External reference
10.1161/cir.0000000000000664
10.1161/cir.0000000000000664 · External reference
Parkinson’s disease
10.1016/j.mcna.2018.10.014 · 2019 · External reference
Cardiovascular risks associated with gender and aging
2019 · External reference
Cardiorenal syndrome: an overview
10.1053/j.ackd.2018.08.004 · 2018 · External reference
Cardiorenal syndrome
10.1016/j.jacc.2008.07.051 · 2008 · External reference
Autophagy as a therapeutic target for chronic kidney disease and the roles of TGF-Β1 in autophagy and kidney fibrosis
10.3390/cells12030412 · 2023 · External reference
Movement disorders in chronic kidney disease – a descriptive review
10.1016/j.jstrokecerebrovasdis.2020.105408 · 2021 · External reference
Association of disorders in mineral metabolism with progression of chronic kidney disease
10.2215/cjn.02101205 · 2006 · External reference
Cardiac abnormalities in Parkinson’s disease and parkinsonism
10.1016/j.jocn.2018.04.031 · 2018 · External reference
Calcium channels in the heart: disease states and drugs
10.3390/cells11060943 · 2022 · External reference
Arterial calcification in chronic kidney disease: key roles for calcium and phosphate
10.1161/circresaha.110.234914 · 2011 · External reference
Parkinson’s disease outside the brain: targeting the autonomic nervous system
10.1016/s1474-4422(21)00219-2 · 2021 · External reference
Felodipine induces autophagy in mouse brains with pharmacokinetics amenable to repurposing
2019 · External reference
Cardiovascular and autonomic alterations in rats with parkinsonism induced by 6-OHDA and treated with L-DOPA
10.1016/j.lfs.2015.01.032 · 2015 · External reference
Degeneration of dopaminergic neurons due to metabolic alterations and Parkinson’s disease
2016 · External reference
Association of cardiovascular risk burden with risk of dementia and brain pathologies: a population-based cohort study
10.1002/alz.12343 · 2021 · External reference
Gender and CVD- Does It Really Matters?
10.1016/j.cpcardiol.2023.101604 · 2023 · External reference
Calcium, bioenergetics, and neuronal vulnerability in Parkinson’s disease
10.1074/jbc.r112.410530 · 2013 · External reference
Calcium and Parkinson’s disease
10.1016/j.bbrc.2016.08.168 · 2017 · External reference
The role of the tripartite synapse in the heart: how glial cells may contribute to the physiology and pathophysiology of the intracardiac nervous system
10.1152/ajpcell.00363.2020 · 2021 · External reference
Parkinson’s: a syndrome rather than a disease?
10.1007/s00702-016-1667-6 · 2017 · External reference
Environmental pollution and chronic kidney disease
10.7150/ijms.51594 · 2021 · External reference
Epidemiology of cardiorenal syndrome
10.1053/j.ackd.2018.08.009 · 2018 · External reference
Novel pathway for an old neurotransmitter: dopamine-induced neuronal calcium signalling via receptor-independent mechanisms
10.1016/j.ceca.2010.08.008 · 2010 · External reference
α-Synuclein and dopamine at the crossroads of Parkinson’s disease
10.1016/j.tins.2010.09.004 · 2010 · External reference
Disruption of mitochondrial homeostasis: the role of pink1 in Parkinson’s disease
10.3390/cells10113022 · 2021 · External reference
Genetics of cardiovascular disease: how far are we from personalized Cvd risk prediction and management?
10.3390/ijms22084182 · 2021 · External reference
10.1111/neup.12691
10.1111/neup.12691 · External reference
Autonomic control of ventricular function in health and disease: current state of the art
10.1007/s10286-023-00948-8 · 2023 · External reference
Cardiac dopamine D1 receptor triggers ventricular arrhythmia in chronic heart failure
10.1038/s41467-020-18128-x · 2020 · External reference
MicroRNA-124 regulates the expression of MEKK3 in the inflammatory pathogenesis of Parkinson’s disease
10.1186/s12974-018-1053-4 · 2018 · External reference
Correlation between striatal dopamine D2/D3 receptor binding and cardiovascular activity in healthy subjects
10.1016/j.amjhyper.2006.03.005 · 2006 · External reference
Helical α-synuclein forms highly conductive ion channels
10.1021/bi701275p · 2007 · External reference
Calcium-permeable ion channels in the kidney
10.1152/ajprenal.00117.2016 · 2016 · External reference
Relationship between Parkinson’s disease and cardio-cerebrovascular diseases: a mendelian randomized study
10.1038/s41598-023-47708-2 · 2023 · External reference
The role of microglial autophagy in Parkinson’s disease
2022 · External reference