Research graph
References from Aversive memory engrams in the hippocampus. Local targets link to admitted publications; unresolved targets remain external evidence.
Hippocampal neurogenesis regulates forgetting during adulthood and infancy
10.1126/science.1248903 · 2014 · External reference
Adult neurogenesis conserves hippocampal memory capacity
10.1523/jneurosci.2976-17.2018 · 2018 · External reference
Modulation of CA2 neuronal activity increases behavioral responses to fear conditioning in female mice
10.1016/j.nlm.2019.107044 · 2019 · External reference
Adult hippocampal neurogenesis and cognitive flexibility — linking memory and mood
10.1038/nrn.2017.45 · 2017 · External reference
Hippocampal neurogenesis confers stress resilience by inhibiting the ventral dentate gyrus
10.1038/s41586-018-0262-4 · 2018 · External reference
Ventral hippocampal afferents to the nucleus accumbens regulate susceptibility to depression
2015 · External reference
Inhibitory engrams in perception and memory
10.1073/pnas.1701812114 · 2017 · External reference
Aversive stimulus-tuned responses in the CA1 of the dorsal hippocampus
10.1038/s41467-023-42611-w · 2023 · External reference
Adult-born neurons promote cognitive flexibility by improving memory precision and indexing
10.1002/hipo.23373 · 2021 · External reference
Sharpening the blades of the dentate gyrus: how adult-born neurons differentially modulate diverse aspects of hippocampal learning and memory
10.15252/embj.2023113524 · 2023 · External reference
Dentate gyrus contributes to retrieval as well as encoding: evidence from context fear conditioning, recall, and extinction
10.1523/jneurosci.3029-16.2017 · 2017 · External reference
Adult hippocampal neurogenesis, fear generalization, and stress
10.1038/npp.2015.167 · 2016 · External reference
Distinct dorsal and ventral hippocampal CA3 outputs govern contextual fear discrimination
10.1016/j.celrep.2020.01.055 · 2020 · External reference
Assessments of dentate gyrus function: discoveries and debates
10.1038/s41583-023-00710-z · 2023 · External reference
A shared neural ensemble links distinct contextual memories encoded close in time
10.1038/nature17955 · 2016 · External reference
Sparse, environmentally selective expression of Arc RNA in the upper blade of the rodent fascia dentata by brief spatial experience
10.1002/hipo.20091 · 2005 · External reference
Artificially enhancing and suppressing hippocampus-mediated memories
10.1016/j.cub.2019.04.065 · 2019 · External reference
Interregional synaptic maps among engram cells underlie memory formation
10.1126/science.aas9204 · 2018 · External reference
Comorbid anxiety and depression: clinical and conceptual consideration and transdiagnostic treatment
10.1007/978-981-32-9705-0_14 · 2020 · External reference
Chronic activation of fear engrams induces extinction-like behavior in ethanol-exposed mice
10.1002/hipo.23263 · 2021 · External reference
Selective information routing by ventral hippocampal CA1 projection neurons
10.1126/science.aaa3245 · 2015 · External reference
Activity in prelimbic cortex is necessary for the expression of learned, but not innate, fears
10.1523/jneurosci.5327-06.2007 · 2007 · External reference
Dominant activities of fear engram cells in the dorsal dentate gyrus underlie fear generalization in mice
10.1371/journal.pbio.3002679 · 2024 · External reference
Prefrontal somatostatin interneurons encode fear memory
10.1038/s41593-019-0552-7 · 2019 · External reference
Genetic strategies to access activated neurons
10.1016/j.conb.2017.05.014 · 2017 · External reference
Temporal evolution of cortical ensembles promoting remote memory retrieval
10.1038/s41593-018-0318-7 · 2019 · External reference
Selection of distinct populations of dentate granule cells in response to inputs as a mechanism for pattern separation in mice
10.7554/elife.00312 · 2013 · External reference
Hippocampal memory traces are differentially modulated by experience, time, and adult neurogenesis
10.1016/j.neuron.2014.05.018 · 2014 · External reference
From Engrams to Pathologies of the Brain
10.3389/fncir.2017.00023 · 2017 · External reference
Neurogenesis-mediated forgetting minimizes proactive interference
10.1038/ncomms10838 · 2016 · External reference
Social reactivation of fear engrams enhances memory recall
10.1073/pnas.2114230119 · 2022 · External reference
The organization of recent and remote memories
10.1038/nrn1607 · 2005 · External reference
Neurogenesis-dependent remodeling of hippocampal circuits reduces PTSD-like behaviors in adult mice
10.1038/s41380-024-02585-7 · 2024 · External reference
No consolidation without representation: correspondence between neural and psychological representations in recent and remote memory
10.1016/j.neuron.2021.04.025 · 2021 · External reference
Permanent genetic access to transiently active neurons via TRAP: targeted recombination in active populations
10.1016/j.neuron.2013.03.025 · 2013 · External reference
Major dissociation between medial and lateral entorhinal input to dorsal hippocampus
10.1126/science.1110449 · 2005 · External reference
A fear memory engram and its plasticity in the hypothalamic oxytocin system
10.1016/j.neuron.2019.04.029 · 2019 · External reference
Chronic stress disrupts fear extinction and enhances amygdala and hippocampal Fos expression in an animal model of post-traumatic stress disorder
10.1016/j.nlm.2014.01.018 · 2014 · External reference
Inhibitory fear memory engram in the mouse central lateral amygdala
10.1016/j.celrep.2024.114468 · 2024 · External reference
Dorsal and ventral hippocampal adult-born neurons contribute to context fear memory
10.1038/s41386-018-0109-6 · 2018 · External reference
Hippocampal neurogenesis enhancers promote forgetting of remote fear memory after hippocampal reactivation by retrieval
10.7554/elife.17464 · 2016 · External reference
Chronic activation of a negative engram induces behavioral and cellular abnormalities
10.7554/elife.96281 · 2024 · External reference
Anxiety cells in a hippocampal-hypothalamic circuit
10.1016/j.neuron.2018.01.016 · 2018 · External reference
Paradox of pattern separation and adult neurogenesis: a dual role for new neurons balancing memory resolution and robustness
10.1016/j.nlm.2015.10.013 · 2016 · External reference
The rodent hippocampus as a bilateral structure: a review of hemispheric lateralization
10.1002/hipo.23188 · 2020 · External reference
Mnemonic functions for nonlinear dendritic integration in hippocampal pyramidal circuits
10.1016/j.neuron.2016.03.019 · 2016 · External reference
Preferential incorporation of adult-generated granule cells into spatial memory networks in the dentate gyrus
10.1038/nn1847 · 2007 · External reference
Differential control of learning and anxiety along the dorsoventral axis of the Dentate Gyrus
10.1016/j.neuron.2012.12.038 · 2013 · External reference
Adult neurogenesis modulates the hippocampus-dependent period of associative fear memory
10.1016/j.cell.2009.10.020 · 2009 · External reference
Engrams and circuits crucial for systems consolidation of a memory
10.1126/science.aam6808 · 2017 · External reference
Neurogenesis-dependent transformation of hippocampal engrams
10.1016/j.neulet.2021.136176 · 2021 · External reference
The hippocampus and neocortical inhibitory engrams protect against memory interference
10.1016/j.neuron.2018.11.042 · 2019 · External reference
Distinct hippocampal engrams control extinction and relapse of fear memory
10.1038/s41593-019-0361-z · 2019 · External reference
Behavioral pattern separation and its link to the neural mechanisms of fear generalization
10.1093/scan/nsx104 · 2017 · External reference
The role of hippocampal subregions in memory for stimulus associations
10.1016/j.bbr.2010.07.006 · 2010 · External reference
Reversible inactivation of the hippocampal mossy fiber synapses in mice impairs spatial learning, but neither consolidation nor memory retrieval, in the morris navigation task
10.1006/nlme.1999.3931 · 2000 · External reference
Engram size varies with learning and reflects memory content and precision
10.1523/jneurosci.2786-20.2021 · 2021 · External reference
Parallel processing streams in the hippocampus
10.1016/j.conb.2020.03.004 · 2020 · External reference
nature neuroscience Neocortical synaptic engrams for remote contextual memories
10.1038/s41593-022-01223-1 · 2023 · External reference
Reconstructing a new hippocampal engram for systems reconsolidation and remote memory updating
10.1016/j.neuron.2024.11.010 · 2025 · External reference
Stress-related dysfunction of adult hippocampal neurogenesis—an attempt for understanding resilience?
10.3390/ijms22147339 · 2021 · External reference
Brain-derived neurotrophic factor expression in serotonergic neurons improves stress resilience and promotes adult hippocampal neurogenesis
10.1016/j.pneurobio.2022.102333 · 2022 · External reference
Glucocorticoids promote fear generalization by increasing the size of a dentate gyrus engram cell population
10.1016/j.biopsych.2021.04.010 · 2021 · External reference
Stress disrupts engram ensembles in lateral amygdala to generalize threat memory in mice
10.1016/j.cell.2024.10.034 · 2025 · External reference
Pattern separation in the dentate gyrus and CA3 of the hippocampus
10.1126/science.1135801 · 2007 · External reference
The hippocampal-VTA loop: controlling the entry of information into long-term memory
10.1016/j.neuron.2005.05.002 · 2005 · External reference
Optogenetic stimulation of a hippocampal engram activates fear memory recall
10.1038/nature11028 · 2012 · External reference
Adult-born hippocampal neurons bidirectionally modulate entorhinal inputs into the dentate gyrus
10.1126/science.aat8789 · 2019 · External reference
Rapid erasure of hippocampal memory following inhibition of dentate gyrus granule cells
10.1038/ncomms10923 · 2016 · External reference
Retrograde abolition of conditional fear after excitotoxic lesions in the basolateral amygdala of rats: absence of a temporal gradient
10.1037/0735-7044.110.4.718 · 1996 · External reference
The brain in motion: how ensemble fluidity drives memory-updating and flexibility
10.7554/elife.63550 · 2020 · External reference
Modulating neuronal competition dynamics in the dentate gyrus to rejuvenate aging memory circuits
10.1016/j.neuron.2016.08.009 · 2016 · External reference
Functions of adult-born neurons in hippocampal memory interference and indexing
10.1038/s41593-019-0484-2 · 2019 · External reference
Adult hippocampal neurogenesis is abundant in neurologically healthy subjects and drops sharply in patients with Alzheimer’s disease
10.1038/s41591-019-0375-9 · 2019 · External reference
Memory retrieval along the proximodistal axis of CA1
10.1002/hipo.22596 · 2016 · External reference
CA3 retrieves coherent representations from degraded input: direct evidence for CA3 pattern completion and dentate gyrus pattern separation
10.1016/j.neuron.2013.11.017 · 2014 · External reference
CA3 sees the big picture while dentate gyrus splits hairs
10.1016/j.neuron.2014.01.004 · 2014 · External reference
Social memory engram in the hippocampus
10.1016/j.neures.2017.05.007 · 2018 · External reference
Ventral CA1 neurons store social memory
10.1126/science.aaf7003 · 2016 · External reference
Understanding the physical basis of memory: molecular mechanisms of the engram
10.1016/j.jbc.2022.101866 · 2022 · External reference
Hippocampal area CA2 activity supports social investigation following an acute social stress
2024 · External reference
Creating a false memory in the hippocampus
10.1126/science.1239073 · 2013 · External reference
Activating positive memory engrams suppresses depression-like behaviour
10.1038/nature14514 · 2015 · External reference
Neuronal responses to conspecifics in the ventral CA1
10.1016/j.celrep.2019.05.081 · 2019 · External reference
Bidirectional switch of the valence associated with a hippocampal contextual memory engram
10.1038/nature13725 · 2014 · External reference
Localization of a stable neural correlate of associative memory
10.1126/science.1143839 · 2007 · External reference
Stress-induced generalization of negative memories is mediated by an extended hippocampal circuit
10.1038/s41386-021-01174-4 · 2021 · External reference
Brain-wide mapping reveals that engrams for a single memory are distributed across multiple brain regions
10.1038/s41467-022-29384-4 · 2022 · External reference
Increasing adult hippocampal neurogenesis is sufficient to improve pattern separation
10.1038/nature09817 · 2011 · External reference
Left-right functional difference of the rat dorsal hippocampus for short-term memory and long-term memory
10.1016/j.bbr.2020.112478 · 2020 · External reference
Hippocampal cells segregate positive and negative engrams
10.1038/s42003-022-03906-8 · 2022 · External reference
A role for adult neurogenesis in spatial long-term memory
10.1016/j.neuroscience.2004.10.009 · 2005 · External reference
CA1 pyramidal cell diversity enabling parallel information processing in the hippocampus
10.1038/s41593-018-0118-0 · 2018 · External reference
Hippocampal somatostatin interneurons control the size of neuronal memory ensembles
10.1016/j.neuron.2016.01.024 · 2016 · External reference
Medial temporal lobe structures are needed to re-experience remote autobiographical memories: evidence from H.M. and W.R
10.1016/j.neuropsychologia.2005.01.001 · 2005 · External reference
Functional organization of the hippocampal longitudinal axis
10.1038/nrn3785 · 2014 · External reference
Proximodistal heterogeneity of hippocampal CA3 pyramidal neuron intrinsic properties, connectivity, and reactivation during memory recall
10.1016/j.neuron.2017.07.012 · 2017 · External reference
Extrinsic and local glutamatergic inputs of the rat hippocampal CA1 area differentially innervate pyramidal cells and interneurons
10.1002/hipo.20974 · 2012 · External reference
The hippocampal engram as a memory index
10.1177/1179069518815942 · 2018 · External reference
Cortical representations are reinstated by the hippocampus during memory retrieval
10.1016/j.neuron.2014.09.037 · 2014 · External reference
Reactivation of neural ensembles during the retrieval of recent and remote memory
10.1016/j.cub.2012.11.019 · 2013 · External reference
Adult hippocampal neurogenesis for systems consolidation of memory
10.1016/j.bbr.2019.112035 · 2019 · External reference
Dynamic and selective engrams emerge with memory consolidation
10.1038/s41593-023-01551-w · 2024 · External reference
Memory engram storage and retrieval
10.1016/j.conb.2015.07.009 · 2015 · External reference
Memory engram cells have come of age
10.1016/j.neuron.2015.08.002 · 2015 · External reference
The role of engram cells in the systems consolidation of memory
10.1038/s41583-018-0031-2 · 2018 · External reference
Adult-born neurons are necessary for extended contextual discrimination
10.1002/hipo.20895 · 2012 · External reference
Distinct functions of ventral CA1 and dorsal CA2 in social memory
10.1016/j.conb.2020.12.008 · 2021 · External reference
Behavioural and dopaminergic signatures of resilience
10.1038/s41586-022-05328-2 · 2022 · External reference
The perforant path: projections from the entorhinal cortex to the dentate gyrus
10.1016/s0079-6123(07)63003-9 · 2007 · External reference
Intrinsic and extrinsic wiring of CA3: indications for connectional heterogeneity
10.1101/lm.725207 · 2007 · External reference
A disinhibitory microcircuit mediates conditioned social fear in the prefrontal cortex
10.1016/j.neuron.2019.02.026 · 2019 · External reference
Pattern separation in the hippocampus
10.1016/j.tins.2011.06.006 · 2011 · External reference
Memory engram stability and flexibility
10.1038/s41386-024-01979-z · 2024 · External reference
Offline ensemble co-reactivation links memories across days
10.1038/s41586-024-08168-4 · 2025 · External reference
Negative memory engrams in the hippocampus enhance the susceptibility to chronic social defeat stress
10.1523/jneurosci.1958-18.2019 · 2019 · External reference
A ventral CA1 to nucleus accumbens core engram circuit mediates conditioned place preference for cocaine
10.1038/s41593-019-0524-y · 2019 · External reference