Research graph
References from Investigating Pleiotropy Between Depression and Autoimmune Diseases Using the UK Biobank. Local targets link to admitted publications; unresolved targets remain external evidence.
Autoimmune diseases and severe infections as risk factors for mood disorders: A nationwide study
10.1001/jamapsychiatry.2013.1111 · 2013 · External reference
The prevalence of comorbid depression in adults with diabetes
10.2337/diacare.24.6.1069 · 2001 · External reference
Major depression in multiple sclerosis: A population-based perspective
10.1212/01.wnl.0000095964.34294.b4 · 2003 · External reference
Depression and anxiety in people with inflammatory bowel disease
10.1136/jech.55.10.716 · 2001 · External reference
Depression and the risk of autoimmune disease: A nationally representative, prospective longitudinal study
10.1017/s0033291715001488 · 2015 · External reference
Genetic factors underlying the bidirectional relationship between autoimmune and mental disorders – Findings from a Danish population-based study
10.1016/j.bbi.2020.06.014 · 2021 · External reference
Classical human leukocyte antigen alleles and C4 haplotypes are not significantly associated with depression
10.1016/j.biopsych.2019.06.031 · 2020 · External reference
Immunity and mental illness: Findings from a Danish population-based immunogenetic study of seven psychiatric and neurodevelopmental disorders
10.1038/s41431-019-0402-9 · 2019 · External reference
What have we learned from six years of GWAS in autoimmune diseases, and what is next?
10.1016/j.coi.2012.09.001 · 2012 · External reference
A bidirectional relationship between depression and the autoimmune disorders - New perspectives from the National Child Development Study
10.1371/journal.pone.0173015 · 2017 · External reference
Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression
10.1038/s41588-018-0090-3 · 2018 · External reference
Cross-disorder analysis of schizophrenia and 19 immune-mediated diseases identifies shared genetic risk
10.1093/hmg/ddz145 · 2019 · External reference
The UK Biobank resource with deep phenotyping and genomic data
10.1038/s41586-018-0579-z · 2018 · External reference
Unresolved reference
1992 · External reference
Mental health in UK Biobank – Development, implementation and results from an online questionnaire completed by 157 366 participants: A reanalysis
10.1192/bjo.2019.100 · 2020 · External reference
Multiple measures of depression to enhance validity of major depressive disorder in the UK Biobank
10.1192/bjo.2020.145 · 2021 · External reference
Prevalence and characteristics of probable major depression and bipolar disorder within UK Biobank: Cross-sectional study of 172,751 participants
10.1371/journal.pone.0075362 · 2013 · External reference
Second-generation PLINK: Rising to the challenge of larger and richer datasets
10.1186/s13742-015-0047-8 · 2015 · External reference
Robust relationship inference in genome-wide association studies
10.1093/bioinformatics/btq559 · 2010 · External reference
Unresolved reference
External reference
FlashPCA2: Principal component analysis of Biobank-scale genotype datasets
10.1093/bioinformatics/btx299 · 2017 · External reference
Multiple common variants for celiac disease influencing immune gene expression
10.1038/ng.543 · 2010 · External reference
Association analyses identify 38 susceptibility loci for inflammatory bowel disease and highlight shared genetic risk across populations
10.1038/ng.3359 · 2015 · External reference
Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis
10.1038/nature10251 · 2011 · External reference
A genome-wide association study of myasthenia gravis
10.1001/jamaneurol.2014.4103 · 2015 · External reference
Large scale meta-analysis characterizes genetic architecture for common psoriasis associated variants
2017 · External reference
Genetic variation at the glycosaminoglycan metabolism pathway contributes to the risk of psoriatic arthritis but not psoriasis
10.1136/annrheumdis-2018-214158 · 2019 · External reference
Genetics of rheumatoid arthritis contributes to biology and drug discovery
10.1038/nature12873 · 2014 · External reference
Genetic association analyses implicate aberrant regulation of innate and adaptive immunity genes in the pathogenesis of systemic lupus erythematosus
10.1038/ng.3434 · 2015 · External reference
PRSice-2: Polygenic Risk Score software for biobank-scale data
10.1093/gigascience/giz082 · 2019 · External reference
Optimal management of pernicious anemia
2012 · External reference
Unravelling the genetic complexity of autoimmune thyroid disease: HLA, CTLA-4 and beyond
10.1111/j.1365-2249.2004.02424.x · 2004 · External reference
A genome-wide meta-analysis of six type 1 diabetes cohorts identifies multiple associated loci
10.1371/journal.pgen.1002293 · 2011 · External reference
Myasthenia gravis
10.1136/bmj.e8497 · 2012 · External reference
Identification of multiple risk variants for ankylosing spondylitis through high-density genotyping of immune-related loci
10.1038/ng.2667 · 2013 · External reference
Incidence, prevalence and treatment burden of polymyalgia rheumatica in the UK over two decades: A population-based study
10.1136/annrheumdis-2018-213883 · 2018 · External reference
The incidence of rheumatoid arthritis in the UK: Comparisons using the 2010 ACR/EULAR classification criteria and the 1987 ACR classification criteria. Results from the Norfolk Arthritis Register
10.1136/annrheumdis-2012-201960 · 2013 · External reference
Variants at multiple loci implicated in both innate and adaptive immune responses are associated with Sjögren's syndrome
10.1038/ng.2792 · 2013 · External reference
The incidence and prevalence of systemic lupus erythematosus in the UK, 1999–2012
10.1136/annrheumdis-2014-206334 · 2016 · External reference
A fast method that uses polygenic scores to estimate the variance explained by genome-wide marker panels and the proportion of variants affecting a trait
10.1016/j.ajhg.2015.06.005 · 2015 · External reference
LD score regression distinguishes confounding from polygenicity in genome-wide association studies
10.1038/ng.3211 · 2015 · External reference
Comorbid depression in medical diseases
10.1038/s41572-020-0200-2 · 2020 · External reference
Peripheral blood cell-stratified subgroups of inflamed depression
10.1016/j.biopsych.2019.11.017 · 2020 · External reference
Cumulative childhood stress and autoimmune diseases in adults
10.1097/psy.0b013e3181907888 · 2009 · External reference
The effect of multiple adverse childhood experiences on health: A systematic review and meta-analysis
10.1016/s2468-2667(17)30118-4 · 2017 · External reference
Comparison of sociodemographic and health-related characteristics of UK Biobank participants with those of the general population
10.1093/aje/kwx246 · 2017 · External reference
Generalisability of results from UK Biobank: Comparison with a pooling of 18 cohort studies
2019 · External reference
Analysis of polygenic risk score usage and performance in diverse human populations
2019 · External reference
