Research graph
References from Identifying the Common Genetic Basis of Antidepressant Response. Local targets link to admitted publications; unresolved targets remain external evidence.
Global, regional, and national incidence, prevalence, and years lived with disability for 310 diseases and injuries, 1990–2015: A systematic analysis for the Global Burden of Disease Study 2015
10.1016/s0140-6736(16)31678-6 · 2016 · External reference
Long-term suicide risk of depression in the Lundby cohort 1947–1997—Severity and gender
10.1111/j.1600-0447.2007.01136.x · 2008 · External reference
Cost of depression in Europe
2006 · External reference
Antidepressant use among persons aged 12 and over: United States, 2011-2014
2017 · External reference
NHS prescribed record number of antidepressants last year
10.1136/bmj.l1508 · 2019 · External reference
Comparative efficacy and acceptability of 21 antidepressant drugs for the acute treatment of adults with major depressive disorder: A systematic review and network meta-analysis
2018 · External reference
Evaluation of outcomes with citalopram for depression using measurement-based care in STAR∗ D: Implications for clinical practice
10.1176/appi.ajp.163.1.28 · 2006 · External reference
Switching antidepressant class does not improve response or remission in treatment-resistant depression
10.1097/jcp.0b013e3182228619 · 2011 · External reference
Addressing the side effects of contemporary antidepressant drugs: A comprehensive review
10.4068/cmj.2018.54.2.101 · 2018 · External reference
Impact of polymorphisms of cytochrome-P450 isoenzymes 2C9, 2C19 and 2D6 on plasma concentrations and clinical effects of antidepressants in a naturalistic clinical setting
10.1007/s00228-004-0766-8 · 2004 · External reference
Effect of cytochrome P450 enzyme polymorphisms on pharmacokinetics of venlafaxine
10.1097/ftd.0b013e3181fcf94d · 2011 · External reference
CYP2C19 genotype predicts steady state escitalopram concentration in GENDEP
10.1177/0269881111414451 · 2012 · External reference
Pharmacogenomics of antidepressant and antipsychotic treatment: How far have we got and where are we going?
10.3389/fpsyt.2020.00094 · 2020 · External reference
Does obtaining CYP2D6 and CYP2C19 pharmacogenetic testing predict antidepressant response or adverse drug reactions?
10.1016/j.psychres.2018.12.053 · 2019 · External reference
Common genetic variation and antidepressant efficacy in major depressive disorder: A meta-analysis of three genome-wide pharmacogenetic studies
10.1176/appi.ajp.2012.12020237 · 2013 · External reference
The International SSRI Pharmacogenomics Consortium (ISPC): A genome-wide association study of antidepressant treatment response
10.1038/tp.2015.47 · 2015 · External reference
Genome-wide association study of treatment-resistance in depression and meta-analysis of three independent samples, 2018/11/23
10.1192/bjp.2018.256 · 2019 · External reference
Genetic predictors of response to serotonergic and noradrenergic antidepressants in major depressive disorder: A genome-wide analysis of individual-level data and a meta-analysis
10.1371/journal.pmed.1001326 · 2012 · External reference
New insights into the pharmacogenomics of antidepressant response from the GENDEP and STAR∗ D studies: Rare variant analysis and high-density imputation
10.1038/tpj.2017.44 · 2018 · External reference
Contribution of common genetic variants to antidepressant response
10.1016/j.biopsych.2012.10.030 · 2013 · External reference
Genome-wide association study of antidepressant treatment resistance in a population-based cohort using health service prescription data and meta-analysis with GENDEP
10.1038/s41397-019-0067-3 · 2020 · External reference
RICOPILI: Rapid Imputation for COnsortias PIpeLIne
10.1093/bioinformatics/btz633 · 2020 · External reference
MAGMA: Generalized gene-set analysis of GWAS data
10.1371/journal.pcbi.1004219 · 2015 · External reference
Integrative approaches for large-scale transcriptome-wide association studies
10.1038/ng.3506 · 2016 · External reference
Novel insight into the aetiology of autism spectrum disorder gained by integrating expression data with genome-wide association statistics
10.1016/j.biopsych.2019.04.034 · 2019 · External reference
Bayesian test for colocalisation between pairs of genetic association studies using summary statistics
10.1371/journal.pgen.1004383 · 2014 · External reference
GCTA: A tool for genome-wide complex trait analysis
10.1016/j.ajhg.2010.11.011 · 2011 · External reference
Estimation of SNP heritability from dense genotype data
10.1016/j.ajhg.2013.10.015 · 2013 · External reference
PRSice-2: Polygenic Risk Score software for biobank-scale data
10.1093/gigascience/giz082 · 2019 · External reference
Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression
10.1038/s41588-018-0090-3 · 2018 · External reference
Genome-wide association study identifies 30 loci associated with bipolar disorder
10.1038/s41588-019-0397-8 · 2019 · External reference
Common schizophrenia alleles are enriched in mutation-intolerant genes and in regions under strong background selection
10.1038/s41588-018-0059-2 · 2018 · External reference
Discovery of the first genome-wide significant risk loci for attention deficit/hyperactivity disorder
10.1038/s41588-018-0269-7 · 2019 · External reference
Identification of common genetic risk variants for autism spectrum disorder
10.1038/s41588-019-0344-8 · 2019 · External reference
A major role for common genetic variation in anxiety disorders
10.1038/s41380-019-0559-1 · 2020 · External reference
Genome-wide association study meta-analysis of the Alcohol Use Disorders Identification Test (AUDIT) in two population-based cohorts
10.1176/appi.ajp.2018.18040369 · 2018 · External reference
Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals
10.1038/s41588-018-0147-3 · 2018 · External reference
A fast method that uses polygenic scores to estimate the variance explained by genome-wide marker panels and the proportion of variants affecting a trait
10.1016/j.ajhg.2015.06.005 · 2015 · External reference
An atlas of genetic correlations across human diseases and traits
10.1038/ng.3406 · 2015 · External reference
Effects of risperidone augmentation in patients with treatment-resistant depression: Results of open-label treatment followed by double-blind continuation
10.1038/sj.npp.1301113 · 2006 · External reference
Integrated genome-wide methylation and expression analyses reveal functional predictors of response to antidepressants
10.1038/s41398-019-0589-0 · 2019 · External reference
Efficacy, safety, and tolerability of augmentation pharmacotherapy with aripiprazole for treatment-resistant depression in late life: A randomised, double-blind, placebo-controlled trial
10.1016/s0140-6736(15)00308-6 · 2015 · External reference
Cohort profile: The Australian genetics of depression study
10.1136/bmjopen-2019-032580 · 2020 · External reference
Schizophrenia genetics: Where next?
10.1093/schbul/sbr031 · 2011 · External reference
A systematic meta-review of predictors of antidepressant treatment outcome in major depressive disorder
10.1016/j.jad.2018.09.067 · 2019 · External reference
Atypical antipsychotic augmentation for treatment-resistant depression: A systematic review and network meta-analysis
10.1093/ijnp/pyv060 · 2015 · External reference
Genetics of response to cognitive behavior therapy in adults with major depression: A preliminary report
10.1038/s41380-018-0289-9 · 2019 · External reference
Socioeconomic status and anxiety as predictors of antidepressant treatment response and suicidal ideation in older adults
10.1007/s00127-008-0436-8 · 2009 · External reference
Pea3 transcription factors, Etv4 and Etv5, are required for proper hippocampal dendrite development and plasticity
10.1093/cercor/bhw372 · 2018 · External reference
The role of neural plasticity in depression: From hippocampus to prefrontal cortex
10.1155/2017/6871089 · 2017 · External reference
Purification and characterization of native spliceosomes suitable for three-dimensional structural analysis
10.1017/s1355838202021088 · 2002 · External reference
A genomewide association study of citalopram response in major depressive disorder
10.1016/j.biopsych.2009.08.029 · 2010 · External reference
Genome-wide pharmacogenetics of antidepressant response in the GENDEP project
10.1176/appi.ajp.2009.09070932 · 2010 · External reference
Treatment outcomes of depression: The pharmacogenomic research network antidepressant medication pharmacogenomic study
10.1097/jcp.0000000000000099 · 2014 · External reference
