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References from High Polygenic Risk Scores Are Associated With Early Age of Onset of Alcohol Use Disorder in Adolescents and Young Adults at Risk. Local targets link to admitted publications; unresolved targets remain external evidence.
Prevalence, correlates, disability, and comorbidity of DSM–IV alcohol abuse and dependence in the United States: Results from the National Epidemiologic Survey on Alcohol and Related Conditions
10.1001/archpsyc.64.7.830 · 2007 · External reference
A family study of alcohol dependence: Coaggregation of multiple disorders in relatives of alcohol-dependent probands [published correction appears in Arch Gen Psychiatry 2005; 62:848]
10.1001/archpsyc.61.12.1246 · 2004 · External reference
Alcohol consumption in demographic subpopulations: An epidemiologic overview
10.35946/arcr.v38.1.02 · 2016 · External reference
Age trends in rates of substance use disorders across ages 18–90: Differences by gender and race/ethnicity
10.1016/j.drugalcdep.2017.08.027 · 2017 · External reference
10.1017/s0033291706007690
10.1017/s0033291706007690 · 2006 · External reference
Race-ethnicity and the prevalence and co-occurrence of Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, alcohol and drug use disorders and Axis I and II disorders: United States, 2001 to 2002
10.1016/j.comppsych.2005.11.001 · 2006 · External reference
Epidemiology of DSM-5 alcohol use disorder: Results from the National Epidemiologic Survey on Alcohol and Related Conditions III
10.1001/jamapsychiatry.2015.0584 · 2015 · External reference
Prevalence of 12-month alcohol use, high-risk drinking, and DSM-IV alcohol use disorder in the United States, 2001–2002 to 2012–2013: Results from the National Epidemiologic Survey on Alcohol and Related Conditions
10.1001/jamapsychiatry.2017.2161 · 2017 · External reference
Age at onset of alcohol use and its association with DSM-IV alcohol abuse and dependence: Results from the National Longitudinal Alcohol Epidemiologic Survey
10.1016/s0899-3289(97)90009-2 · 1997 · External reference
Age at first alcohol use: A risk factor for the development of alcohol disorders
10.1176/appi.ajp.157.5.745 · 2000 · External reference
Causal influence of age at first drink on alcohol involvement in adulthood and its moderation by familial context
10.15288/jsad.2013.74.703 · 2013 · External reference
Reporting bias in the association between age at first alcohol use and heavy episodic drinking
2011 · External reference
Age of first drinking and adult alcohol problems: Systematic review of prospective cohort studies
10.1136/jech-2013-203402 · 2014 · External reference
Is ‘age at first drink’ a useful concept in alcohol research and prevention? We doubt that
10.1111/add.12980 · 2016 · External reference
Relationship of age of first drink to child behavioral problems and family psychopathology
10.1097/01.alc.0000183190.32692.c7 · 2005 · External reference
A model to determine the likely age of an adolescent’s first drink of alcohol
10.1542/peds.2012-0880 · 2013 · External reference
A GABRA2 polymorphism improves a model for prediction of drinking initiation
10.1016/j.alcohol.2017.03.003 · 2017 · External reference
Evidence for an interaction between age at first drink and genetic influences on DSM-IV alcohol dependence symptoms
10.1111/j.1530-0277.2009.01044.x · 2009 · External reference
Lifetime co-morbidity of DSM-IV disorders in the US National Comorbidity Survey Replication Adolescent Supplement (NCS-A)
10.1017/s0033291712000025 · 2012 · External reference
Depressive and anxiety disorders predicting first incidence of alcohol use disorders: Results of the Netherlands Study of Depression and Anxiety (NESDA)
10.4088/jcp.12m08159 · 2013 · External reference
Psychiatric comorbidity among adolescents with substance use disorders: Findings from the MECA study
10.1097/00004583-199906000-00016 · 1999 · External reference
Comparison of parent, peer, psychiatric, and cannabis use influences across stages of offspring alcohol involvement: Evidence from the COGA prospective study
10.1111/acer.13293 · 2017 · External reference
Reliability and validity of an internalizing symptom scale based on the adolescent and adult Semi-Structured Assessment for the Genetics of Alcoholism (SSAGA)
10.1080/00952990.2018.1476520 · 2019 · External reference
Neurogenetic adaptive mechanisms in alcoholism
10.1126/science.2882604 · 1987 · External reference
Types of alcoholics, I. Evidence for an empirically derived typology based on indicators of vulnerability and severity
10.1001/archpsyc.1992.01820080007002 · 1992 · External reference
Developmental sequence from disruptive behavior diagnosis to adolescent alcohol dependence
10.1176/appi.ajp.158.12.2022 · 2001 · External reference
Childhood psychiatric disorders as risk factor for subsequent substance abuse: A meta-analysis
10.1016/j.jaac.2017.05.004 · 2017 · External reference
The boundaries of the internalizing and externalizing genetic spectra in men and women
10.1017/s0033291713000585 · 2014 · External reference
Prediction of individual genetic risk to disease from genome-wide association studies
10.1101/gr.6665407 · 2007 · External reference
Common polygenic variation contributes to risk of schizophrenia and bipolar disorder
10.1038/nature08185 · 2009 · External reference
Polygenic risk scores in clinical psychology: Bridging genomic risk to individual differences
10.1146/annurev-clinpsy-050817-084847 · 2018 · External reference
Polygenic risk scores in psychiatry: Will they be useful for clinicians?
10.12688/f1000research.18491.1 · 2019 · External reference
Genome-wide polygenic scores for common diseases identify individuals with risk equivalent to monogenic mutations
10.1038/s41588-018-0183-z · 2018 · External reference
Polygenic prediction of weight and obesity trajectories from birth to adulthood
10.1016/j.cell.2019.03.028 · 2019 · External reference
Exploring the predictive power of polygenic scores derived from genome-wide association studies: A study of 10 complex traits
10.1093/bioinformatics/btw745 · 2017 · External reference
Polygenic risk and progression to bipolar or psychotic disorders among individuals diagnosed with unipolar depression in early life
10.1176/appi.ajp.2020.19111195 · 2020 · External reference
Development of alcohol use disorder as a function of age, severity, and comorbidity with externalizing and internalizing disorders in a young adult cohort
2019 · External reference
Genome-wide polygenic scores for age at onset of alcohol dependence and association with alcohol-related measures
10.1038/tp.2016.27 · 2016 · External reference
Using polygenic scores for identifying individuals at increased risk of substance use disorders in clinical and population samples
10.1038/s41398-020-00865-8 · 2020 · External reference
A new, semi-structured psychiatric interview for use in genetic linkage studies: A report on the reliability of the SSAGA
10.15288/jsa.1994.55.149 · 1994 · External reference
Genome-wide association studies of alcohol dependence, DSM-IV criterion count and individual criteria
10.1111/gbb.12579 · 2019 · External reference
Genome-wide association studies of the self-rating of effects of ethanol (SRE)
10.1111/adb.12800 · 2020 · External reference
Unresolved reference
2013 · External reference
Unresolved reference
1994 · External reference
Genome-wide association study of alcohol consumption and use disorder in 274,424 individuals from multiple populations [published corrections appear in Nat Commun 2019; 10:2275 and Nat Commun 2019; 10:4050]
10.1038/s41467-019-09480-8 · 2019 · External reference
Genome-wide association study of maximum habitual alcohol intake in >140,000 U.S. European and African American veterans yields novel risk loci
10.1016/j.biopsych.2019.03.984 · 2019 · External reference
PLINK: A tool set for whole-genome association and population-based linkage analyses
10.1086/519795 · 2007 · External reference
Polygenic prediction via Bayesian regression and continuous shrinkage priors
10.1038/s41467-019-09718-5 · 2019 · External reference
Improving polygenic prediction in ancestrally diverse populations
10.1038/s41588-022-01054-7 · 2022 · External reference
Frailty models for survival data
10.1007/bf00985760 · 1995 · External reference
Unresolved reference
2016 · External reference
Polygenic risk scores for genetic counseling in psychiatry: Lessons learned from other fields of medicine
10.1016/j.neubiorev.2020.11.021 · 2021 · External reference
Assessment of a modified DSM-5 diagnosis of alcohol use disorder in a genetically informative population
10.1111/j.1530-0277.2012.01954.x · 2013 · External reference
Transancestral GWAS of alcohol dependence reveals common genetic underpinnings with psychiatric disorders
10.1038/s41593-018-0275-1 · 2018 · External reference
Genome-wide association study of more than 40,000 bipolar disorder cases provides new insights into the underlying biology
10.1038/s41588-021-00857-4 · 2021 · External reference
Unresolved reference
2018 · External reference
Analysis of polygenic risk score usage and performance in diverse human populations
10.1038/s41467-019-11112-0 · 2019 · External reference
Cognitive behavioral interventions for alcohol and drug use disorders: Through the stage model and back again
10.1037/adb0000311 · 2017 · External reference
Diagnosis and pharmacotherapy of alcohol use disorder: A review
10.1001/jama.2018.11406 · 2018 · External reference
Adolescent alcohol drinking and its long-range consequences. Studies with animal models
10.1007/0-306-48626-1_6 · 2005 · External reference
Gene expression changes in glutamate and GABA-A receptors, neuropeptides, ion channels, and cholesterol synthesis in the periaqueductal gray following binge-like alcohol drinking by adolescent alcohol-preferring (P) rats
10.1111/acer.13056 · 2016 · External reference
Gene expression changes in the ventral hippocampus and medial prefrontal cortex of adolescent alcohol-preferring (P) rats following binge-like alcohol drinking
10.1016/j.alcohol.2017.09.002 · 2018 · External reference
Drug addiction, dysregulation of reward, and allostasis
10.1016/s0893-133x(00)00195-0 · 2001 · External reference
Alcoholism: Allostasis and beyond
10.1097/01.alc.0000057122.36127.c2 · 2003 · External reference
What should a psychiatrist know about genetics? Review and recommendations from the Residency Education Committee of the International Society of Psychiatric Genetics
10.4088/jcp.17nr12046 · 2018 · External reference
Comprehensive functional genomic resource and integrative model for the human brain
10.1126/science.aat8464 · 2018 · External reference
Impact of pharmacogenomics on clinical outcomes in major depressive disorder in the GUIDED trial: A large, patient- and rater-blinded, randomized, controlled study
10.1016/j.jpsychires.2019.01.003 · 2019 · External reference