Research graph
References from Genome-wide by Environment Interaction Study of Stressful Life Events and Hospital-Treated Depression in the iPSYCH2012 Sample. Local targets link to admitted publications; unresolved targets remain external evidence.
The epidemiology of depression across cultures
10.1146/annurev-publhealth-031912-114409 · 2013 · External reference
Epidemiology of Adult DSM-5 major depressive disorder and its specifiers in the United States
10.1001/jamapsychiatry.2017.4602 · 2018 · External reference
Genetic epidemiology of major depression: Review and meta-analysis
10.1176/appi.ajp.157.10.1552 · 2000 · External reference
The effects of stressful life events on depression
10.1146/annurev.psych.48.1.191 · 1997 · External reference
Stress and depression
10.1146/annurev.clinpsy.1.102803.143938 · 2005 · External reference
Early adversity and risk for moderate to severe unipolar depressive disorder in adolescence and adulthood: A register-based study of 978,647 individuals
10.1016/j.jad.2017.03.014 · 2017 · External reference
Childhood adversity and adult psychiatric disorder in the US National Comorbidity Survey
10.1017/s0033291797005588 · 1997 · External reference
The enduring effects of abuse and related adverse experiences in childhood. A convergence of evidence from neurobiology and epidemiology
10.1007/s00406-005-0624-4 · 2006 · External reference
Adverse childhood experiences and the risk of depressive disorders in adulthood
10.1016/j.jad.2003.12.013 · 2004 · External reference
Stressful life events, genetic liability, and onset of an episode of major depression in women
10.1176/ajp.152.6.833 · 1995 · External reference
Influence of life stress on depression: Moderation by a polymorphism in the 5-HTT gene
10.1126/science.1083968 · 2003 · External reference
Interacting effect of BDNF Val66Met polymorphism and stressful life events on adolescent depression
10.1111/j.1601-183x.2012.00843.x · 2012 · External reference
Interaction between genetic polymorphisms and stressful life events in first episode depression
10.1016/j.jad.2009.02.023 · 2009 · External reference
Genetic variants in the DRD2 gene moderate the relationship between stressful life events and depressive symptoms in adults: Cardiovascular risk in young Finns study
10.1097/psy.0b013e31806bf365 · 2007 · External reference
Brain galanin system genes interact with life stresses in depression-related phenotypes
10.1073/pnas.1403649111 · 2014 · External reference
Interactions between life stressors and susceptibility genes (5-HTTLPR and BDNF) on depression in Korean elders
10.1016/j.biopsych.2006.11.020 · 2007 · External reference
Negative life events and corticotropin-releasing-hormone receptor1 gene in recurrent major depressive disorder
10.1038/srep01548 · 2013 · External reference
Interaction between serotonin transporter gene, catechol-O-methyltransferase gene and stressful life events in mood disorders
10.1017/s1461145706006882 · 2007 · External reference
Interaction of FKBP5 gene variants and adverse life events in predicting depression onset: Results from a 10-year prospective community study
10.1176/appi.ajp.2011.10111577 · 2011 · External reference
Gene-environment interactions between stress and 5-HTTLPR in depression: A meta-analytic update
10.1016/j.jad.2017.09.050 · 2018 · External reference
Collaborative meta-analysis finds no evidence of a strong interaction between stress and 5-HTTLPR genotype contributing to the development of depression
10.1038/mp.2017.44 · 2018 · External reference
Interaction between stress and the BDNF Val66Met polymorphism in depression: A systematic review and meta-analysis
10.1186/1741-7015-12-7 · 2014 · External reference
The serotonin transporter promoter variant (5-HTTLPR), stress, and depression meta-analysis revisited: Evidence of genetic moderation
10.1001/archgenpsychiatry.2010.189 · 2011 · External reference
Interaction between the serotonin transporter gene (5-HTTLPR), stressful life events, and risk of depression: A meta-analysis
10.1001/jama.2009.878 · 2009 · External reference
Serotonin transporter genotype 5HTTLPR as a marker of differential susceptibility? A meta-analysis of child and adolescent gene-by-environment studies
10.1038/tp.2012.73 · 2012 · External reference
Interaction between early-life stress and FKBP5 gene variants in major depressive disorder and post-traumatic stress disorder: A systematic review and meta-analysis
10.1016/j.jad.2017.08.066 · 2018 · External reference
BDNF Val66Met polymorphism, life stress and depression: A meta-analysis of gene-environment interaction
10.1016/j.jad.2017.10.024 · 2018 · External reference
Effect of polygenic risk scores on depression in childhood trauma
10.1192/bjp.bp.113.143081 · 2014 · External reference
Polygenic interactions with environmental adversity in the aetiology of major depressive disorder
10.1017/s0033291715002172 · 2016 · External reference
A direct test of the diathesis-stress model for depression
10.1038/mp.2017.130 · 2018 · External reference
Polygenic risk, stressful life events and depressive symptoms in older adults: A polygenic score analysis
10.1017/s0033291714002839 · 2015 · External reference
Does Childhood Trauma Moderate Polygenic Risk for Depression? A Meta-analysis of 5765 Subjects From the Psychiatric Genomics Consortium
10.1016/j.biopsych.2017.09.009 · 2018 · External reference
Polygenic liability, stressful life events and risk for secondary-treated depression in early life: A nationwide register-based case-cohort study [published online ahead of print May 5]
2021 · External reference
Poor replication of candidate genes for major depressive disorder using genome-wide association data
10.1038/mp.2010.38 · 2011 · External reference
A critical review of the first 10 years of candidate gene-by-environment interaction research in psychiatry
10.1176/appi.ajp.2011.11020191 · 2011 · External reference
No evidence that schizophrenia candidate genes are more associated with schizophrenia than noncandidate genes
10.1016/j.biopsych.2017.06.033 · 2017 · External reference
Genome-wide meta-analysis of depression identifies 102 independent variants and highlights the importance of the prefrontal brain regions
10.1038/s41593-018-0326-7 · 2019 · External reference
No support for historical candidate gene or candidate gene-by-interaction hypotheses for major depression across multiple large samples
10.1176/appi.ajp.2018.18070881 · 2019 · External reference
Genome-wide association study (GWAS) and genome-wide by environment interaction study (GWEIS) of depressive symptoms in African American and Hispanic/Latina Women
10.1002/da.22484 · 2016 · External reference
Genome-wide environment interaction between depressive state and stressful life events
10.4088/jcp.15l10127 · 2016 · External reference
The first pilot genome-wide gene-environment study of depression in the Japanese population
10.1371/journal.pone.0160823 · 2016 · External reference
Genome-wide by environment interaction studies of depressive symptoms and psychosocial stress in UK Biobank and Generation Scotland
10.1038/s41398-018-0360-y · 2019 · External reference
Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression
10.1038/s41588-018-0090-3 · 2018 · External reference
Agreement between prospective and retrospective measures of childhood maltreatment: A systematic review and meta-analysis
10.1001/jamapsychiatry.2019.0097 · 2019 · External reference
Consistency in adult reporting of adverse childhood experiences
10.1017/s0033291715002032 · 2016 · External reference
Could polygenic risk scores be useful in psychiatry?: A review
10.1001/jamapsychiatry.2020.3042 · 2021 · External reference
The iPSYCH2012 case-cohort sample: New directions for unravelling genetic and environmental architectures of severe mental disorders
10.1038/mp.2017.196 · 2018 · External reference
Analysis of case-cohort designs
10.1016/s0895-4356(99)00102-x · 1999 · External reference
Asymptotic distribution theory and efficiency results for case-cohort studies
10.1214/aos/1176350691 · 1988 · External reference
A case-cohort design for epidemiologic cohort studies and disease prevention trials
10.1093/biomet/73.1.1 · 1986 · External reference
Association of polygenic liabilities for major depression, bipolar disorder, and schizophrenia with risk for depression in the Danish population
10.1001/jamapsychiatry.2018.4166 · 2019 · External reference
The Danish Psychiatric Central Research Register
10.1177/1403494810395825 · 2011 · External reference
The Danish Civil Registration System
10.1177/1403494810387965 · 2011 · External reference
The Danish National Patient Register
10.1177/1403494811401482 · 2011 · External reference
Danish registers on personal labour market affiliation
10.1177/1403494811408483 · 2011 · External reference
Storage policies and use of the Danish Newborn Screening Biobank
10.1007/s10545-007-0631-x · 2007 · External reference
RICOPILI: Rapid Imputation for COnsortias PIpeLIne
10.1093/bioinformatics/btz633 · 2020 · External reference
Analysis of case-cohort data: A comparison of different methods
10.1016/j.jclinepi.2006.06.022 · 2007 · External reference
LocusZoom: Regional visualization of genome-wide association scan results
10.1093/bioinformatics/btq419 · 2010 · External reference
The UK Biobank resource with deep phenotyping and genomic data
10.1038/s41586-018-0579-z · 2018 · External reference
Genome-wide gene-environment analyses of major depressive disorder and reported lifetime traumatic experiences in UK Biobank
10.1038/s41380-019-0546-6 · 2020 · External reference
Second-generation PLINK: Rising to the challenge of larger and richer datasets
10.1186/s13742-015-0047-8 · 2015 · External reference
Drug resistance in brain diseases and the role of drug efflux transporters
10.1038/nrn1728 · 2005 · External reference
Cerebral amyloid-beta proteostasis is regulated by the membrane transport protein ABCC1 in mice
10.1172/jci57867 · 2011 · External reference
Proteomics. Tissue-based map of the human proteome
10.1126/science.1260419 · 2015 · External reference
Genetic contributions to variation in general cognitive function: A meta-analysis of genome-wide association studies in the CHARGE consortium (N = 53949)
10.1038/mp.2014.188 · 2015 · External reference
The novel membrane-bound proteins MFSD1 and MFSD3 are putative SLC transporters affected by altered nutrient intake
10.1007/s12031-016-0867-8 · 2017 · External reference
Gene--environment-wide association studies: Emerging approaches
10.1038/nrg2764 · 2010 · External reference
Psychiatric genomics: An update and an agenda
10.1176/appi.ajp.2017.17030283 · 2018 · External reference
Incidence of medically treated depression in Denmark among individuals 15-44 years old: A comprehensive overview based on population registers
10.1111/acps.13028 · 2019 · External reference