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References from Somatostatin Receptor 4 Agonism Normalizes Stress-Related Excessive Amygdala Glutamate Release and Pavlovian Aversion Learning and Memory in Rodents. Local targets link to admitted publications; unresolved targets remain external evidence.
A role for the neuropeptide somatostatin in the neurobiology of behaviors associated with substances abuse and affective disorders
10.1016/j.neuropharm.2020.107983 · 2020 · External reference
Somatostatin, neuronal vulnerability and behavioral emotionality
10.1038/mp.2014.184 · 2015 · External reference
Amygdala microcircuits controlling learned fear
10.1016/j.neuron.2014.04.042 · 2014 · External reference
Molecular evidence for BDNF- and GABA-related dysfunctions in the amygdala of female subjects with major depression
10.1038/mp.2011.113 · 2012 · External reference
GABA-related transcripts in the dorsolateral prefrontal cortex in mood disorders
10.1017/s1461145710001616 · 2011 · External reference
Reduced somatostatin in subgenual anterior cingulate cortex in major depression
10.1016/j.nbd.2011.01.014 · 2011 · External reference
Characterization of neurons expressing the novel analgesic drug target somatostatin receptor 4 in mouse and human brains
10.3390/ijms21207788 · 2020 · External reference
Somatostatin receptor subtype 4 activation is involved in anxiety and depression-like behavior in mouse models
10.1016/j.neuropharm.2015.09.021 · 2016 · External reference
Higher susceptibility of somatostatin 4 receptor gene-deleted mice to chronic stress-induced behavioral and neuroendocrine alterations
10.1016/j.neuroscience.2017.01.039 · 2017 · External reference
Roles of hippocampal somatostatin receptor subtypes in stress response and emotionality
10.1038/npp.2016.281 · 2017 · External reference
Acute corticosterone treatment is sufficient to induce anxiety and amygdaloid dendritic hypertrophy
10.1073/pnas.0705615105 · 2008 · External reference
Behavioral and neurobiological consequences of prolonged glucocorticoid exposure in rats: Relevance to depression
10.1016/j.pnpbp.2010.03.005 · 2010 · External reference
Differential effects of peripheral and brain tumor necrosis factor on inflammation, sickness, emotional behavior and memory in mice
10.1016/j.bbi.2016.08.001 · 2016 · External reference
Mouse social stress induces increased fear conditioning, helplessness and fatigue to physical challenge together with markers of altered immune and dopamine function
10.1016/j.neuropharm.2014.05.039 · 2014 · External reference
Pharmacological inhibition of TRPC4 and TRPC5 with HC-070 ameliorates behaviors associated with anxiety and depression in mice
2018 · External reference
Mouse chronic social stress increases blood and brain kynurenine pathway activity and fear behaviour: Both effects are reversed by inhibition of indoleamine 2,3-dioxygenase
10.1016/j.bbi.2015.12.020 · 2016 · External reference
Mouse psychosocial stress reduces motivation and cognitive function in operant reward tests: A model for reward pathology with effects of agomelatine
10.1016/j.euroneuro.2016.06.009 · 2016 · External reference
Chronic social stress induces peripheral and central immune activation, blunted mesolimbic dopamine function, and reduced reward-directed behaviour
10.1016/j.ynstr.2018.01.004 · 2018 · External reference
Chronic social stress leads to reduced gustatory reward salience and effort valuation in mice
10.3389/fnbeh.2018.00134 · 2018 · External reference
Chronic social stress in mice alters energy status including higher glucose need but lower brain utilization
10.1016/j.psyneuen.2020.104747 · 2020 · External reference
The stressed synapse: The impact of stress and glucocorticoids on glutamate transmission
10.1038/nrn3138 · 2012 · External reference
Cortical functional hyperconnectivity in a mouse model of depression and selective network effects of ketamine
10.1093/brain/awx142 · 2017 · External reference
Molecular mechanisms of fear learning and memory
10.1016/j.cell.2011.10.009 · 2011 · External reference
Oligodendrocyte gene expression is reduced by and influences effects of chronic social stress in mice
10.1111/gbb.12475 · 2019 · External reference
Both mineralocorticoid and glucocorticoid receptors regulate emotional memory in mice
10.1016/j.nlm.2010.09.005 · 2010 · External reference
Amygdala inhibitory circuits and the control of fear memory
10.1016/j.neuron.2009.05.026 · 2009 · External reference
Synaptic encoding of fear extinction in mPFC-amygdala circuits
10.1016/j.neuron.2013.09.025 · 2013 · External reference
Amygdala interneuron subtypes control fear learning through disinhibition
10.1038/nature13258 · 2014 · External reference
Prefrontal somatostatin interneurons encode fear memory
10.1038/s41593-019-0552-7 · 2020 · External reference
Hippocampal SSTR4 somatostatin receptors control the selection of memory strategies
10.1007/s00213-008-1204-x · 2009 · External reference
A neural circuit for excessive feeding driven by environmental context in mice
10.1038/s41593-021-00875-9 · 2021 · External reference
Activation of brain somatostatin 2 receptors stimulates feeding in mice: Analysis of food intake microstructure
10.1016/j.physbeh.2010.09.009 · 2010 · External reference
Human somatostatin SST4 receptor transgenic mice: construction and brain expression pattern characterization
10.3390/ijms22073758 · 2021 · External reference