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References from Alcohol disrupts long-term potentiation at hippocampus-medium spiny neuron synapses in the medial shell of the nucleus accumbens. Local targets link to admitted publications; unresolved targets remain external evidence.
Chronic ethanol exposures leads to a negative affective state in female rats that is accompanied by a paradoxical decrease in ventral hippocampus excitability
10.3389/fnins.2021.669075 · 2021 · External reference
A hippocampus-accumbens code guides goal-directed appetitive behavior
10.1038/s41467-024-47361-x · 2024 · External reference
Synaptic and behavioral profile of multiple glutamatergic inputs to the nucleus accumbens
10.1016/j.neuron.2012.09.040 · 2012 · External reference
10.1523/eneuro.0087-23.2023
10.1523/eneuro.0087-23.2023 · External reference
Closing the gate in the limbic striatum: prefrontal suppression of hippocampal and thalamic inputs
10.1016/j.neuron.2013.01.032 · 2013 · External reference
Biological substrates of reward and aversion: a nucleus accumbens activity hypothesis
10.1016/j.neuropharm.2008.06.075 · 2009 · External reference
Dependence-induced increases in ethanol self-administration in mice are blocked by the CRF1 receptor antagonist antalarmin and by CRF1 receptor knockout
10.1016/j.pbb.2007.03.009 · 2007 · External reference
Sex-specific mechanisms underlie long-term potentiation at hippocampus→medium spiny neuron synapses in the medial shell of the nucleus accumbens
10.1523/jneurosci.0100-24.2024 · 2024 · External reference
Sex differences in low-dose ethanol effects on motivated behavior and limbic corticostriatal activity in mice
10.1111/acer.70264 · 2026 · External reference
An upside to reward sensitivity: the hippocampus supports enhanced reinforcement learning in adolescence
10.1016/j.neuron.2016.08.031 · 2016 · External reference
Addiction, anhedonia, and comorbid mood disorder. A narrative review
10.3389/fpsyt.2019.00311 · 2019 · External reference
Chronic intermittent ethanol exposure in mice leads to an up-regulation of CRH/CRHR1 signaling
10.1111/acer.12686 · 2015 · External reference
Chronic intermittent ethanol exposure selectively increases synaptic excitability in the ventral domain of the rat hippocampus
10.1016/j.neuroscience.2018.11.028 · 2019 · External reference
Dopamine and hippocampal input to the nucleus accumbens play an essential role in the search for food in an unpredictable environment
10.3758/bf03332121 · 1999 · External reference
Emerging role for nucleus accumbens medium spiny neuron subtypes in depression
10.1016/j.biopsych.2016.09.007 · 2017 · External reference
Anhedonia in substance use disorders: a systematic review of its nature, course and clinical correlates
10.1177/0004867413508455 · 2014 · External reference
Differential effects of acute and repeated stress on hippocampus and amygdala inputs to the nucleus accumbens shell
10.1017/s1461145713000618 · 2013 · External reference
Limbic and cortical information processing in the nucleus accumbens
10.1016/j.tins.2008.08.002 · 2008 · External reference
Network synchrony in the nucleus accumbens in vivo
10.1523/jneurosci.21-12-04498.2001 · 2001 · External reference
Alcohol dependence and the ventral hippocampal influence on alcohol drinking in male mice
10.1016/j.alcohol.2022.10.004 · 2023 · External reference
Association between real-world experiential diversity and positive affect relates to hippocampal-striatal functional connectivity
10.1038/s41593-020-0636-4 · 2020 · External reference
Suppression of L-type voltage-gated calcium channel-dependent synaptic plasticity by ethanol: analysis of miniature synaptic currents and dendritic calcium transients
10.1124/jpet.103.055137 · 2003 · External reference
Adolescent substance use and functional connectivity between the ventral striatum and hippocampus
10.1016/j.bbr.2020.112678 · 2020 · External reference
Functional interaction between the hippocampus and nucleus accumbens shell is necessary for the acquisition of appetitive spatial context conditioning
10.1523/jneurosci.1615-08.2008 · 2008 · External reference
Acute effects of ethanol on hippocampal long-term potentiation and long-term depression are mediated by different mechanisms
10.1016/j.neuroscience.2005.08.002 · 2005 · External reference
Cell type-specific synaptic encoding of ethanol exposure in the nucleus accumbens shell
10.1016/j.neuroscience.2014.06.063 · 2014 · External reference
Specific and nonspecific effects of ethanol vapor on plasma corticosterone in mice
10.1016/0741-8329(92)90092-o · 1992 · External reference
Ethanol experience enhances glutamatergic ventral hippocampal inputs to D1 receptor-expressing medium spiny neurons in the nucleus accumbens shell
2019 · External reference
Neurocircuitry of addiction
10.1038/npp.2009.110 · 2010 · External reference
Reward behaviour is regulated by the strength of hippocampus–nucleus accumbens synapses
10.1038/s41586-018-0740-8 · 2018 · External reference
Anhedonia requires MC4R-mediated synaptic adaptations in nucleus accumbens
10.1038/nature11160 · 2012 · External reference
Synaptic plasticity mechanisms common to learning and alcohol use disorder
10.1101/lm.046722.117 · 2018 · External reference
NMDA receptor-mediated synaptic excitation selectively inhibited by ethanol in hippocampal slice from adult rat
10.1523/jneurosci.10-04-01372.1990 · 1990 · External reference
Synaptic interactions among excitatory afferents to nucleus accumbens neurons: Hippocampal gating of prefrontal cortical input
10.1523/jneurosci.15-05-03622.1995 · 1995 · External reference
Selective alterations of NMDAR function and plasticity in D1 and D2 medium spiny neurons in the nucleus accumbens shell following chronic intermittent ethanol exposure
10.1016/j.neuropharm.2016.03.004 · 2017 · External reference
The brain reward circuitry in mood disorders
10.1038/nrn3381 · 2013 · External reference
The nucleus accumbens: mechanisms of addiction across drug classes reflect the importance of glutamate homeostasis
10.1124/pr.116.012484 · 2016 · External reference
Cannabinoids and glucocorticoids in the basolateral amygdala modulate hippocampal–accumbens plasticity after stress
10.1038/npp.2015.238 · 2016 · External reference
Cocaine place conditioning strengthens location-specific hippocampal coupling to the nucleus accumbens
10.1016/j.neuron.2018.04.015 · 2018 · External reference
Dorsal and ventral hippocampal sharp-wave ripples activate distinct nucleus accumbens networks
10.1016/j.neuron.2019.11.022 · 2020 · External reference
Membrane potential synchrony of simultaneously recorded striatal spiny neuronsin vivo
10.1038/28848 · 1998 · External reference
Optogenetic modulation of neural circuits that underlie reward seeking
10.1016/j.biopsych.2011.11.010 · 2012 · External reference
A hippocampus-accumbens tripartite neuronal motif guides appetitive memory in space
10.1016/j.cell.2018.12.037 · 2019 · External reference
Acute alcohol and cognition: remembering what it causes us to forget
10.1016/j.alcohol.2019.03.006 · 2019 · External reference
The brain on drugs: from reward to addiction
10.1016/j.cell.2015.07.046 · 2015 · External reference
The origins of two-state spontaneous membrane potential fluctuations of neostriatal spiny neurons
10.1523/jneurosci.16-07-02397.1996 · 1996 · External reference
A ventral CA1 to nucleus accumbens core engram circuit mediates conditioned place preference for cocaine
10.1038/s41593-019-0524-y · 2019 · External reference
Acute and chronic effects of ethanol on learning-related synaptic plasticity
10.1016/j.alcohol.2013.09.045 · 2014 · External reference