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References from Central and peripheral changes in oxygenation and temperatures induced by intravenous nicotine in freely moving male rats. Local targets link to admitted publications; unresolved targets remain external evidence.
Antinociceptive action of nicotine and its methiodide derivatives in mice and rats
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The neuronal pathways mediating the behavioral and addictive properties of nicotine
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Influence of nicotine on cardiovascular and hormonal effects of cigarette smoking
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Smoking produces rapid rise of [11C]nicotine in human brain
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Brain temperature effects of intravenous heroin: State dependency, environmental modulation, and the effects of dose
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In a Rat Model of Opioid Maintenance, the G Protein-Biased Mu Opioid Receptor Agonist TRV130 Decreases Relapse to Oxycodone Seeking and Taking and Prevents Oxycodone-Induced Brain Hypoxia
10.1016/j.biopsych.2020.02.014 · 2020 · External reference
Nicotine addiction and nicotinic receptors: lessons from genetically modified mice
10.1038/nrn2849 · 2010 · External reference
Combined treatment with naloxone and the alpha2 adrenoceptor antagonist atipamezole reversed brain hypoxia induced by a fentanyl-xylazine mixture in a rat model
10.1038/s41386-023-01782-2 · 2024 · External reference
Understanding brain mechanisms in nicotine reinforcement
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Nicotine self-administration in rats
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Neuroanatomical circuitry mediating the sensory impact of nicotine in the central nervous system
10.1002/jnr.23477 · 2015 · External reference
Nicotine self-administration in rats
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Neurovascular coupling: motive unknown
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Nicotine-induced activation of locus coeruleus neurons–an analysis of peripheral versus central induction
10.1007/bf00169131 · 1994 · External reference
Excitatory and inhibitory responses of dopamine neurons in the ventral tegmental area to nicotine
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Molecular Mechanisms Associated with Nicotine Pharmacology and Dependence
10.1007/164_2019_252 · 2020 · External reference
The importance of sensory nerve endings as sites of drug action
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Effect of repeated nicotine exposure on core temperature and motor activity in male and female rats
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Expression of neuronal nicotinic acetylcholine receptors in rat vagal pulmonary sensory neurons
10.1016/j.resp.2007.11.006 · 2008 · External reference
Role of primary sensory neurons in the central effects of nicotine
10.1007/bf00212839 · 1988 · External reference
Hypothermia produced by nicotine perfused through the cerabral ventricles of the unanaesthetized monkey
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Acid-sensitive ion channels and receptors
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Influence of mecamylamine and atropine on tolerance development to nicotine hypothermia in rats
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Impact of intravenous nicotine on BOLD signal response to photic stimulation
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Effects of smoking and smoking abstinence on cognition in adolescent tobacco smokers
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Nicotinic nociceptors on perivascular sensory nerve endings
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Brain temperature and its role in physiology and pathophysiology: Lessons from 20 years of thermorecording
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Functional role of peripheral vasoconstriction: not only thermoregulation but much more
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Brain oxygen responses induced by opioids: focus on heroin, fentanyl, and their adulterants
2024 · External reference
The peripheral vascular consequences of smoking
10.1007/bf02329389 · 1991 · External reference
The neurovascular unit in brain function and disease
10.1111/j.1748-1716.2011.02256.x · 2011 · External reference
Blood volume in the rat
1985 · External reference
Critical role of peripheral actions of intravenous nicotine in mediating its central effects
10.1038/npp.2011.104 · 2011 · External reference
Brain oxygen responses induced by arousing stimuli and fentanyl: generalized or structure-specific?
10.1152/ajpregu.00332.2025 · 2026 · External reference
Comparison of fentanyl-induced brain oxygen responses following intravenous and intraperitoneal injections in rats
10.1016/j.neuropharm.2025.110412 · 2025 · External reference
Capsaicin and nicotine both activate a subset of rat trigeminal ganglion neurons
1996 · External reference
Nicotine and behavioral sensitization
10.1007/s12031-009-9230-7 · 2010 · External reference
A diallel analysis of nicotine-induced hypothermia
10.1016/s0091-3057(84)80079-9 · 1984 · External reference
Guidelines on nicotine dose selection for in vivo research
10.1007/s00213-006-0441-0 · 2007 · External reference
Chapter 9 - Nicotine Chemistry, Pharmacology, and Pharmacokinetics
2016 · External reference
Preferential metabolic activation of subcortical brain areas by acute administration of nicotine to rats
10.1038/jcbfm.1990.7 · 1990 · External reference
Nicotine effects on skin: are they positive or negative?
10.1111/j.0906-6705.2004.00274.x · 2004 · External reference
Brain hyperthermia and temperature fluctuations during sexual interaction in female rats
10.1016/j.brainres.2003.12.024 · 2004 · External reference
The neurovascular unit - concept review
10.1111/apha.12250 · 2014 · External reference
Evolution of acid nociception: ion channels and receptors for detecting acid
10.1098/rstb.2019.0291 · 2019 · External reference
AChE-stained horizontal sections of the rat brain in stereotaxic coordinates
10.1016/0165-0270(80)90021-7 · 1980 · External reference
Molecular mechanisms underlying behaviors related to nicotine addiction
10.1101/cshperspect.a012112 · 2013 · External reference
Adolescent and adult rats respond differently to nicotine and alcohol: motor activity and body temperature
10.1016/j.ijdevneu.2004.03.007 · 2004 · External reference
Arterial nicotine kinetics during cigarette smoking and intravenous nicotine administration: implications for addiction
10.1016/s0376-8716(99)00025-3 · 1999 · External reference
Nicotine self-administration in animals and humans: similarities and differences
10.1007/s002130050209 · 1997 · External reference
Kinetics of brain nicotine accumulation in dependent and nondependent smokers assessed with PET and cigarettes containing 11C-nicotine
10.1073/pnas.0909184107 · 2010 · External reference
Acid-base balance: a review of normal physiology
10.1016/j.bjae.2022.06.003 · 2022 · External reference
Nicotine self-administration, extinction responding and reinstatement in adolescent and adult male rats: evidence against a biological vulnerability to nicotine addiction during adolescence
10.1038/sj.npp.1301454 · 2008 · External reference
Influence of smoking and nicotine on cerebral blood flow and metabolic rate of oxygen in man
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Rapid Brain Nicotine Uptake from Electronic Cigarettes
10.2967/jnumed.119.230748 · 2020 · External reference
Nicotine-Induced Limbic Cortical Activation in the Human Brain: A Functional MRI Study
10.1176/ajp.155.8.1009 · 1998 · External reference
Fluctuations in central and peripheral temperatures induced by intravenous nicotine: central and peripheral contributions
10.1016/j.brainres.2011.01.092 · 2011 · External reference
Relationships between oxygen changes in the brain and periphery following physiological activation and the actions of heroin and cocaine
10.1038/s41598-021-85798-y · 2021 · External reference
Nitric oxide-mediated blood flow regulation as affected by smoking and nicotine
10.1016/j.ejphar.2010.09.042 · 2010 · External reference
Cerebral Cortical Vasodilation via Nicotinic Receptors by Heated Tobacco Product Aerosol Extract in Rats
2024 · External reference
Exposure to nicotine and sensitization of nicotine-induced behaviors
10.1016/j.pnpbp.2007.08.038 · 2007 · External reference
Neurobiological Mechanisms of Nicotine Reward and Aversion
10.1124/pharmrev.121.000299 · 2022 · External reference
