Research graph
References from Plant‐based production and characterization of monoclonal antibodies targeting extracellular enveloped proteins of the Mpox Virus. Local targets link to admitted publications; unresolved targets remain external evidence.
Unresolved reference
External reference
Global transmission characteristics of mpox outbreaks: a systematic review and meta-analysis
10.1016/j.eclinm.2025.103526 · 2025 · External reference
Mpox global health crisis: implications and actions
10.4103/apjtm.apjtm_527_24 · 2025 · External reference
10.1080/22221751.2024.2401931
10.1080/22221751.2024.2401931 · External reference
Potent neutralization by antibodies targeting the MPXV A28 protein
10.1038/s41467-025-66344-0 · 2025 · External reference
Human monoclonal antibodies targeting A35 protect from death caused by mpox
10.1016/j.cell.2025.08.004 · 2025 · External reference
Two long-lasting human monoclonal antibodies cross-react with monkeypox virus A35 antigen
10.1038/s41421-023-00556-w · 2023 · External reference
10.1038/s41467-024-48312-2
10.1038/s41467-024-48312-2 · External reference
Biopharmaceutical benchmarks 2022
10.1038/s41587-022-01582-x · 2022 · External reference
Molecular farming for immunization: current advances and future prospects in plant-produced vaccines
10.3390/vaccines13020191 · 2025 · External reference
Plant Molecular farming: a viable platform for recombinant biopharmaceutical production
10.3390/plants9070842 · 2020 · External reference
Molecular farming for new drugs and vaccines: current perspectives on the production of pharmaceuticals in transgenic plants
10.1038/sj.embor.7400470 · 2005 · External reference
Techno-economic analysis of a transient plant-based platform for monoclonal antibody production
10.1080/19420862.2016.1227901 · 2016 · External reference
10.1002/btpr.2896
10.1002/btpr.2896 · External reference
10.1155/2014/256135
10.1155/2014/256135 · External reference
Application of a scalable plant transient gene expression platform for malaria vaccine development
10.3389/fpls.2015.01169 · 2015 · External reference
Rapid production of SARS-CoV-2 receptor binding domain (RBD) and spike specific monoclonal antibody CR3022 in Nicotiana benthamiana
10.1038/s41598-020-74904-1 · 2020 · External reference
Plant-produced biopharmaceuticals: a case of technical developments driving clinical deployment
10.1126/science.aaf6638 · 2016 · External reference
10.1111/pbi.13657
10.1111/pbi.13657 · External reference
10.1111/pbi.13658
10.1111/pbi.13658 · External reference
Plant molecular farming: much more than medicines
10.1146/annurev-anchem-071015-041706 · 2016 · External reference
Plant molecular farming for the production of valuable proteins - critical evaluation of achievements and future challenges
10.1016/j.jplph.2020.153359 · 2021 · External reference
Phase 1 randomized trial of a plant-derived virus-like particle vaccine for COVID-19
10.1038/s41591-021-01370-1 · 2021 · External reference
Efficacy, immunogenicity, and safety of a plant-derived, quadrivalent, virus-like particle influenza vaccine in adults (18-64 years) and older adults (≥65 years): two multicentre, randomised phase 3 trials
10.1016/s0140-6736(20)32014-6 · 2020 · External reference
Monoclonal antibodies B38 and H4 produced in Nicotiana benthamiana neutralize SARS-CoV-2 in vitro
10.3389/fpls.2020.589995 · 2020 · External reference
Characterisation of chikungunya virus neutralising monoclonal antibodies expressed in tobacco plants
10.1016/j.jbiotec.2025.06.014 · 2025 · External reference
Monoclonal antibody produced in plants efficiently treats West Nile virus infection in mice
10.1073/pnas.0914503107 · 2010 · External reference
Engineering, expression in transgenic plants and characterisation of E559, a rabies virus-neutralising monoclonal antibody
10.1093/infdis/jiu085 · 2014 · External reference
A randomized, controlled trial of ZMapp for Ebola virus infection
10.1056/nejmoa1604330 · 2016 · External reference
A broad and potent H1-specific human monoclonal antibody produced in plants prevents influenza virus infection and transmission in guinea pigs
10.3390/v12020167 · 2020 · External reference
Characterization of a plant-derived monoclonal antibody targeting extracellular enveloped virions of Monkeypox virus
2024 · External reference
Advanced plant-based glycan engineering
10.3389/fbioe.2018.00081 · 2018 · External reference
Point-of-care biosensors for infectious disease diagnosis: recent updates and prospects
10.1039/d5ra03897a · 2025 · External reference
10.1007/s00253-026-13736-x
10.1007/s00253-026-13736-x · External reference
Disease-related detection with electrochemical biosensors: a review
10.3390/s17102375 · 2017 · External reference
Geminiviral vectors based on bean yellow dwarf virus for production of vaccine antigens and monoclonal antibodies in plants
10.4161/hv.7.3.14262 · 2011 · External reference
High-level expression and enrichment of norovirus virus-like particles in plants using modified geminiviral vectors
10.1016/j.pep.2018.06.011 · 2018 · External reference
Plant-produced anti-enterovirus 71 (EV71) monoclonal antibody efficiently protects mice against EV71 infection
10.3390/plants8120560 · 2019 · External reference
Evidence of Mpox clade IIb infection in primary human alveolar epithelium
10.1080/22221751.2025.2477845 · 2025 · External reference
Heterogeneity in the A33 protein impacts the cross-protective efficacy of a candidate smallpox DNA vaccine
10.1016/j.virol.2008.04.003 · 2008 · External reference
Examination of the cross-reactivity between vaccinia virus Tiantan strain and monkeypox virus
10.1016/j.jviromet.2023.114772 · 2023 · External reference
L1R, A27L, A33R and B5R vaccinia virus genes expressed by fowlpox recombinants as putative novel orthopoxvirus vaccines
10.1186/1479-5876-11-95 · 2013 · External reference
Pilot production of SARS-CoV-2 related proteins in plants: a proof of concept for rapid repurposing of indoor farms into biomanufacturing facilities
10.3389/fpls.2020.612781 · 2020 · External reference
The production of hemagglutinin-based virus-like particles in plants: a rapid, efficient and safe response to pandemic influenza
10.1111/j.1467-7652.2009.00496.x · 2010 · External reference
High-density transfection with HEK-293 cells allows doubling of transient titers and removes need for a priori DNA complex formation with PEI
10.1002/bit.21596 · 2008 · External reference
CHO cells in biotechnology for production of recombinant proteins: current state and further potential
10.1007/s00253-011-3758-5 · 2012 · External reference
Production of recombinant protein therapeutics in cultivated mammalian cells
10.1038/nbt1026 · 2004 · External reference
High-titer expression of recombinant antibodies by transiently transfected HEK 293-6E cell cultures
10.1186/1753-6561-9-s9-p40 · 2015 · External reference
A simple, robust and highly efficient transient expression system for producing antibodies
10.1016/j.ymeth.2013.07.018 · 2014 · External reference
Systematic review and data-driven insights into CHO cell engineering for next-generation antibody production
10.1080/19420862.2026.2615475 · 2026 · External reference
Development of predictable and high-yield CHO cell line by site-specific integration
10.1186/s13036-025-00610-z · 2025 · External reference
The extracellular domain of vaccinia virus protein B5R affects plaque phenotype, extracellular enveloped virus release, and intracellular actin tail formation
10.1128/jvi.72.3.2429-2438.1998 · 1998 · External reference
Clinical features and management of human monkeypox: a retrospective observational study in the UK
10.1016/s1473-3099(22)00228-6 · 2022 · External reference
Viral dynamics in patients with monkeypox infection: a prospective cohort study in Spain
10.1016/s1473-3099(22)00794-0 · 2023 · External reference
Frequent detection of monkeypox virus DNA in saliva, semen, and other clinical samples from 12 patients, Barcelona, Spain, May to June 2022
10.2807/1560-7917.es.2022.27.28.2200503 · 2022 · External reference
Detecting, quantifying, and isolating Monkeypox virus in suspected cases, Spain
10.3201/eid2907.221229 · 2023 · External reference
