Research graph
References from Enzymatic metal hydride and hydrogen atom transfer reactions: recent developments for synthetic applications. Local targets link to admitted publications; unresolved targets remain external evidence.
Metal-hydrogen bond cleavage reactions of transition metal hydrides: Hydrogen atom, hydride, and proton transfer reactions
1991 · External reference
Catalytic hydrogen atom transfer to alkenes: a roadmap for metal hydrides and radicals
10.1039/d0sc04112b · 2020 · External reference
The high chemofidelity of metal-catalyzed hydrogen atom transfer
10.1021/acs.accounts.8b00337 · 2018 · External reference
Catalytic hydrofunctionalizations of alkenes via hydrogen atom transfer with 3d transition metal complexes (MHAT): a pragmatic approach to recent contributions
10.1016/j.apcata.2025.120379 · 2025 · External reference
Biocatalytic reductions and chemical versatility of the old yellow enzyme family of flavoprotein oxidoreductases
10.1002/cctc.201000094 · 2010 · External reference
Redox out of the box: catalytic versatility across NAD(P)H-dependent oxidoreductases
10.1002/anie.202314740 · 2024 · External reference
Biocatalytic reductive aminations with NAD(P)H-dependent enzymes: enzyme discovery, engineering and synthetic applications
10.1039/d3cs00391d · 2024 · External reference
Engineering ketoreductases for the enantioselective synthesis of chiral alcohols
10.1039/d3cc01474f · 2023 · External reference
Hydrogenase enzymes and their synthetic models: the role of metal hydrides
10.1021/acs.chemrev.6b00180 · 2016 · External reference
Hybrid Chemo-, Bio-, and electrocatalysis for atom-efficient deuteration of cofactors in heavy water
10.1021/acscatal.0c03437 · 2021 · External reference
Abiotic reduction of ketones with silanes catalysed by carbonic anhydrase through an enzymatic zinc hydride
10.1038/s41557-020-00633-7 · 2021 · External reference
Carbonic anhydrase variants catalyze the reduction of dialkyl ketones with high enantioselectivity
2024 · External reference
Conversion of a zinc disilazide to a zinc hydride mediated by LiCl
10.1021/ja102323g · 2010 · External reference
Zinc catalysts for On-Demand hydrogen generation and carbon dioxide functionalization
10.1021/ja308500s · 2012 · External reference
Chemoenzymatic sequential catalysis with carbonic anhydrase for the synthesis of chiral alcohols from alkanes, alkenes, and alkynes
10.1021/acscatal.4c02481 · 2024 · External reference
Designing γ-Carbonic anhydrase as a broad-scope metalloreductase with ultrathermostability and organic-solvent tolerance
10.1021/acscatal.5c02152 · 2025 · External reference
De Novo Design of Miniature and Efficient Metallo-Ketoreductases
10.1021/jacs.6c00732 · 2026 · External reference
Repurposing myoglobin into an abiological asymmetric ketoreductase
10.1016/j.chempr.2024.06.010 · 2024 · External reference
Metalloporphyrins as catalytic models for studying hydrogen and oxygen evolution and oxygen reduction reactions
10.1021/acs.accounts.1c00753 · 2022 · External reference
Stereoconvergent reduction of alkenes using a repurposed iron-based dioxygenase
10.1038/s44160-025-00788-6 · 2025 · External reference
Stereoconvergent reduction of activated alkenes by a nicotinamide free synergistic photobiocatalytic system
10.1021/acscatal.0c02489 · 2020 · External reference
Cooperative asymmetric reactions combining photocatalysis and enzymatic catalysis
10.1038/s41586-018-0413-7 · 2018 · External reference
Metalloenzyme-catalyzed asymmetric transfer hydrogenation for the synthesis of chiral amines
10.1002/anie.202511298 · 2025 · External reference
Biocatalytic hydrogen atom transfer: an invigorating approach to free-radical reactions
10.1016/j.cbpa.2018.09.001 · 2019 · External reference
Mn-, Fe-, and Co-Catalyzed radical hydrofunctionalizations of Olefins
10.1021/acs.chemrev.6b00334 · 2016 · External reference
Recent advances in applications of metal hydride hydrogen atom transfer for natural product synthesis
10.1039/d5ob01671a · 2026 · External reference
Metal-hydride hydrogen atom transfer (MHAT) reactions in natural product synthesis
10.1039/d1qo01139a · 2021 · External reference
Repurposing Iron- and 2-Oxoglutarate-Dependent oxygenases to catalyze olefin hydration
2023 · External reference
Repurposing haemoproteins for asymmetric metal-catalysed H atom transfer
10.1038/s41586-025-09308-0 · 2025 · External reference
Biocatalytic metal hydrogen atom transfer for asymmetric olefin–olefin coupling
10.1021/jacs.6c01998 · 2026 · External reference
Biocatalytic, asymmetric radical hydrogenation of unactivated alkenes
10.1126/science.aea4737 · 2025 · External reference
Bayesian Optimization–Guided Development of P450BM3-Catalyzed Metal–Hydride Hydrogen Atom Transfer
10.1007/s10562-026-05429-x · 2026 · External reference
Unresolved reference
2026 · External reference
Insights into substrate specificity of geranylgeranyl reductases revealed by the structure of digeranylgeranylglycerophospholipid reductase, an essential enzyme in the biosynthesis of archaeal membrane lipids
10.1016/j.jmb.2010.09.032 · 2010 · External reference
Carbon–carbon double-bond reductases in nature
10.3109/03602532.2014.910219 · 2014 · External reference
Enzymatic asymmetric reduction of unfunctionalized C=C bonds with archaeal geranylgeranyl reductases
10.1002/cbic.202100290 · 2021 · External reference
Hydrogenation of alkenes via cooperative hydrogen atom transfer
10.1021/jacs.0c09544 · 2020 · External reference
Engineered nonheme iron enzymes enable asymmetric hydrogenation of alkenes
10.1021/jacs.6c08443 · 2026 · External reference
Orchestrating metal-hydride reactivity in engineered metalloenzymes: electronic and electrostatic determinants of the reaction mechanism
10.1021/jacs.6c04303 · 2026 · External reference
Electrocatalytic CO2 reduction by a cobalt porphyrin mini-enzyme
10.1039/d4sc07026g · 2025 · External reference
Controlling non-native cobalamin reactivity and catalysis in the transcription factor CarH
10.1021/acscatal.1c04748 · 2022 · External reference
Non-native intramolecular radical cyclization catalyzed by a B12-Dependent enzyme
10.1002/anie.202312893 · 2023 · External reference
An evolved artificial radical cyclase enables the construction of bicyclic terpenoid scaffolds via an H-atom transfer pathway
10.1038/s41557-024-01562-5 · 2024 · External reference
Molecular determinants of efficient cobalt-substituted hemoprotein production in E. coli
10.1021/acssynbio.3c00481 · 2023 · External reference
De novo biosynthesis of a nonnatural cobalt porphyrin cofactor in E. coli and incorporation into hemoproteins
10.1073/pnas.2017625118 · 2021 · External reference
Cobalt-substituted hemoprotein expression
2025 · External reference
Enzymatic metal–hydrogen atom transfer with a cobalt protoporphyrin cofactor
10.1021/jacs.5c19000 · 2026 · External reference
Efficient O-deallylation triggered by cobalt hydride-catalyzed oxidative hydrofunctionalization
2023 · External reference
Evaluating the aqueous stability of Alkyl-/Aryl-Hydrosilanes by NMR spectroscopy and GC-MS
10.1002/cplu.202500310 · 2025 · External reference
Use of in situ FTIR to ensure safe quench of phenylsilane
10.1021/acs.oprd.5c00137 · 2025 · External reference
Cobalt-catalyzed HAT reaction for asymmetric hydrofunctionalization of alkenes and nucleophiles
2023 · External reference
